447 research outputs found
HRTS: A Hierarchical Reactive Time Synchronization Protocol for Wireless Sensor Networks
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
The Inflammatory Response to Double Stranded DNA in Endothelial Cells Is Mediated by NFÎşB and TNFÎą
- Author
- A Shimony
- A Takaoka
- AB Imaeda
- Arno W. Tilles
- BL Bennett
- C Dong
- C Fiuza
- CJ Chen
- DA Muruve
- DB Stetson
- F Takeshita
- H Hemmi
- H Kono
- Holger K. Eltzschig
- J Heidemann
- JC Lee
- JE Grundy
- JR Vane
- JS Pober
- JS Pober
- JT Kuvin
- JW Jones
- K Jones
- KA Fitzgerald
- Kevin R. King
- KJ Ishii
- KJ Wieder
- L Unterholzner
- LL Stoll
- Martin L. Yarmush
- MW Covert
- N Yan
- O Takeuchi
- R Jindal
- R Schreck
- RM Levy
- Rohit Jindal
- S Rafii
- SE Warren
- SJ Patel
- SL Gerson
- SL Werner
- Suraj J. Patel
- V Hornung
- V Hornung
- VA Rathinam
- Y Okabe
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/02/2011
- Field of study
Endothelial cells represent an important barrier between the intravascular compartment and extravascular tissues, and therefore serve as key sensors, communicators, and amplifiers of danger signals in innate immunity and inflammation. Double stranded DNA (dsDNA) released from damaged host cells during injury or introduced by pathogens during infection, has emerged as a potent danger signal. While the dsDNA-mediated immune response has been extensively studied in immune cells, little is known about the direct and indirect effects of dsDNA on the vascular endothelium. In this study we show that direct dsDNA stimulation of endothelial cells induces a potent proinflammatory response as demonstrated by increased expression of ICAM1, E-selectin and VCAM1, and enhanced leukocyte adhesion. This response was dependent on the stress kinases JNK and p38 MAPK, required the activation of proinflammatory transcription factors NFÎşB and IRF3, and triggered the robust secretion of TNFÎą for sustained secondary activation of the endothelium. DNA-induced TNFÎą secretion proved to be essential in vivo, as mice deficient in the TNF receptor were unable to mount an acute inflammatory response to dsDNA. Our findings suggest that the endothelium plays an active role in mediating dsDNA-induced inflammatory responses, and implicate its importance in establishing an acute inflammatory response to sterile injury or systemic infection, where host or pathogen derived dsDNA may serve as a danger signal.United States. Dept. of Defense (CDMRP Predoctoral Training Award)National Institutes of Health (U.S.) (NIH BioMEMS Resource Center Grant P41 EB-002503)National Institutes of Health (U.S.) (NIH Grant RO1AI063795)Shriners Hospital for Childre
Clinical and Functional Characterization of a Patient Carrying a Compound Heterozygous Pericentrin Mutation and a Heterozygous IGF1 Receptor Mutation
- Author
- A Juul
- A Rauch
- A Schmidt
- B Delaval
- B Ducos
- C Dumitrescu
- D Kotzot
- D Kotzot
- D LeRoith
- Daniela Friebe
- Desiree Dunstheimer
- Eva MĂźller
- F Brancati
- F Majewski
- F Majewski
- Hironori Waki
- I Huang-Doran
- I Kjaer
- J Klammt
- J Klammt
- JG Hall
- JL Badano
- JM Sorof
- JP Liu
- JS Choi
- JS Waldron
- JĂźrgen Klammt
- JĂźrgen Kratzsch
- K Inagaki
- K Raile
- L Faivre
- M Willems
- MB Bober
- MH Muders
- MH Muders
- MJ Abuzzahab
- MJ Walenkamp
- O Larsson
- P Fang
- P Fang
- P Kannu
- Peter H. Heidemann
- R Di Bartolomeo
- RA Booth
- Roland Pfäffle
- S Tartare-Deckert
- Sandy Laue
- SN Naccache
- T Kruis
- T Ligensa
- T Wallborn
- Tassilo Kruis
- Tillmann Wallborn
- Wieland Kiess
- X Lou
- Y Kawashima
- Publication venue
- Public Library of Science
- Publication date
- 31/05/2012
- Field of study
Intrauterine and postnatal longitudinal growth is controlled by a strong genetic component that regulates a complex network of endocrine factors integrating them with cellular proliferation, differentiation and apoptotic processes in target tissues, particularly the growth centers of the long bones. Here we report on a patient born small for gestational age (SGA) with severe, proportionate postnatal growth retardation, discreet signs of skeletal dysplasia, microcephaly and moyamoya disease. Initial genetic evaluation revealed a novel heterozygous IGF1R p.Leu1361Arg mutation affecting a highly conserved residue with the insulin-like growth factor type 1 receptor suggestive for a disturbance within the somatotropic axis. However, because the mutation did not co-segregate with the phenotype and functional characterization did not reveal an obvious impairment of the ligand depending major IGF1R signaling capabilities a second-site mutation was assumed. Mutational screening of components of the somatotropic axis, constituents of the IGF signaling system and factors involved in cellular proliferation, which are described or suggested to provoke syndromic dwarfism phenotypes, was performed. Two compound heterozygous PCNT mutations (p.[Arg585X];[Glu1774X]) were identified leading to the specification of the diagnosis to MOPD II. These investigations underline the need for careful assessment of all available information to derive a firm diagnosis from a sequence aberration
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arora S
- Asawatangtrakuldee C
- Asghar MI
- Askew A
- Assran Y
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baeni L
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ban Y
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Bardak C
- Barfuss AF
- Bargassa P
- Barge D
- Baringer P
- Barker A
- Barnes VE
- Barnett BA
- Barney D
- Barone L
- Barrett M
- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
- Baty C
- Bauer G
- Bauerdick LAT
- Baumgartel D
- Baur U
- Bayshev I
- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
- Beaupere N
- Bedjidian M
- Beernaert K
- Behrenhoff W
- Behrens U
- Belforte S
- Beliy N
- Belknap D
- Bell AJ
- Bell KW
- Bellan P
- Bellan R
- Bellato M
- Bellinger JN
- Belotelov I
- Belyaev A
- Belyaev A
- Benaglia A
- Bencze G
- Bendavid J
- Benedetti D
- Benelli G
- Benhabib L
- Beni N
- Benucci L
- Benussi L
- Benvenuti AC
- Beranek S
- Beretvas A
- Bergauer T
- Berger J
- Bergholz M
- Beri SB
- Bernardes CA
- Bernardini J
- Bernet C
- Berry D
- Berry E
- Berryhill J
- Bertl W
- Berzano U
- Besancon M
- Betchart B
- Bethani A
- Betts RR
- Beuselinck R
- Bhat PC
- Bhatnagar V
- Bhattacharya S
- Bhattacharya S
- Bhatti A
- Bialas W
- Bialkowska H
- Bian JG
- Bianchi G
- Bianchini L
- Bianco S
- Biasini M
- Biino C
- Bilei GM
- Bilin B
- Bilinskas MJ
- Bilki B
- Bilmis S
- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
- Blobel V
- Bloch D
- Bloch I
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Blyweert S
- Bobrovskyi S
- Boccali T
- Bocci A
- Bochenek J
- Bodek A
- Bodin D
- Boimska B
- Boldizsar L
- Bolla G
- Bolognesi S
- Bolton T
- Bonacorsi D
- Bonato A
- Bondu O
- Bontenackels M
- Boos E
- Bornheim A
- Borras K
- Borrello L
- Bortignon P
- Bortoletto D
- Bose S
- Bose T
- Bostock F
- Botta C
- Boudoul G
- Boulahouache C
- Boumediene D
- Bourilkov D
- Boutemeur M
- Boutle S
- Braibant-Giacomelli S
- Branca A
- Branson JG
- Breedon R
- Breto G
- Breuker H
- Brew C
- Brigliadori L
- Brigljevic V
- Brinkerhoff A
- Broccolo G
- Brochero Cifuentes JA
- Brom JM
- Brona G
- Brooke JJ
- Broutin C
- Brown RM
- Brownson E
- Brun H
- Bruno G
- Bryer AG
- Buchmann MA
- Buchmuller O
- Bunkowski K
- Bunn J
- Buontempo S
- Burgmeier A
- Burkett K
- Busson P
- Busza W
- Butler JN
- Butler PH
- Butt J
- Butz E
- Bylsma B
- Cabrera A
- Cabrillo IJ
- Caebergs T
- Cakir A
- Calabria C
- Calderon De La Barca Sanchez M
- Calderon A
- Cali IA
- Calligaris L
- Callner J
- Calvert B
- Calvo E
- Campagnari C
- Campbell A
- Camporesi T
- Capiluppi P
- Caponeri B
- Cappello G
- Cardaci M
- Carlin R
- Carlsmith D
- Carrillo Moreno S
- Carroll R
- Cartiglia N
- Carvalho W
- Casal B
- Casimiro Linares E
- Castaldi R
- Castello R
- Castilla-Valdez H
- Castro A
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- Caudron J
- Caulfield M
- Cavallari F
- Cavallo FR
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- Cavanaugh R
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- Ceballos GG
- Cepeda M
- Cerati GB
- Cerci DS
- Cerci S
- Cerizza G
- Cerminara G
- Cerrada M
- Chabert EC
- Chadwick M
- Chakaberia I
- Chamizo Llatas M
- Chan M
- Chang P
- Chang S
- Chang YH
- Chang YH
- Chang YW
- Chanon N
- Chao Y
- Charaf O
- Charlot C
- Chasco M
- Chasserat J
- Chatrchyan S
- Chatterjee A
- Chauhan S
- Checchia P
- Chen GM
- Chen HS
- Chen J
- Chen KF
- Chen KH
- Chen M
- Chen Y
- Chen Z
- Cherepanov V
- Chertok M
- Chetluru V
- Cheung HWK
- Chhibra SS
- Chierici R
- Chiochia V
- Chiorboli M
- Chlebana F
- Cho Y
- Choi M
- Choi S
- Choi Y
- Choi YK
- Chou JP
- Choudhary BC
- Choudhury RK
- Choudhury S
- Christiansen T
- Chuang SH
- Chung J
- Chung YS
- Chwalek T
- Ciesielski R
- Cihangir S
- Cimmino A
- Cipriano PMR
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clarida W
- Clement E
- Clerbaux B
- Cline D
- CMS Collaboration
- Cockerill DJA
- Codispoti G
- Colafranceschi S
- Colaleo A
- Cole JE
- Colino N
- Collard C
- Colling D
- Conetti S
- Contardo D
- Conte E
- Contreras-Campana C
- Contreras-Campana E
- Conway J
- Conway R
- Cooper SI
- Cooper W
- Cornelis T
- Correa Martins Junior M
- Cortezon EP
- Cossutti F
- Costa M
- Costa S
- Costantini S
- Coughlan JA
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Creanza D
- Cremaldi LM
- Cripps N
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cuplov V
- Cure B
- Cushman P
- Cussans D
- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
- Daci N
- Dahmes B
- Dahms T
- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- Dauncey P
- David A
- Davids M
- Davies G
- de Barbaro P
- De Benedetti A
- De Boer W
- de Cassagnac RG
- De Cosa A
- de Fatis TT
- De Filippis N
- De Gruttola M
- De Guio F
- De Jeneret JD
- De La Cruz B
- De La Cruz-Burelo E
- De Lentdecker G
- De Mattia M
- de Monchenault GH
- De Oliveira Martins C
- De Palma M
- De Roeck A
- de Troconiz JF
- De Visscher S
- De Wolf EA
- Deisher A
- Deiters K
- Dejardin M
- del Arbol PMR
- Del Re D
- Delaere C
- Delgado Peris A
- Deliomeroglu M
- Dell'Orso R
- Della Negra M
- Della Ricca G
- Demaria N
- Demina R
- Demortier L
- Denegri D
- Deniz M
- Depasse P
- Dermenev A
- Dero V
- Dhingra N
- Di Giovanni GP
- Di Guida S
- Di Marco E
- Di Matteo L
- Diamond B
- Dias FA
- Diemoz M
- Dierlamm A
- Dietz C
- Dietz-Laursonn E
- Diez Pardos C
- Dimitrov A
- Dinardo ME
- Dirkes G
- Dissertori G
- Dittmar M
- Djordjevic M
- Dobrzynski L
- Dobson M
- Dobur D
- Doesburg R
- Dogangun O
- Dolen J
- Dominguez Vazquez D
- Dominguez A
- Dominik W
- Don CKK
- Dorigo T
- Dorney B
- Doroba K
- Dozen C
- Draeger J
- Dragicevic M
- Dragoiu C
- Drell BR
- Dremin I
- Drouhin F
- Drozdetskiy A
- du Pree T
- Duarte Campderros J
- Duarte J
- Dubinin M
- Dudero PR
- Dudko L
- Duenser M
- Dugad S
- Duggan D
- Dumanoglu I
- Dupont-Sagorin N
- Duric S
- Duris J
- Durkin LS
- Duru F
- Dutta D
- Dutta S
- Dutta V
- Dzelalija M
- Eads M
- Eartly DP
- Eckerlin G
- Ecklund KM
- Eckstein D
- Edelhoff M
- Edelmaier CJ
- Eerola P
- Efron J
- Eggert N
- Ekmedzic M
- El Mamouni H
- Elgammal S
- Elliott-Peisert A
- Ellison J
- Elmer P
- Elvira VD
- Enderle H
- Engh D
- Eno SC
- Epshteyn V
- Erbacher R
- Erdmann M
- Erdmann W
- Erfle J
- Erhan S
- Ero J
- Erofeeva M
- Ershov A
- Esen S
- Eshaq Y
- Eskut E
- Etesami SM
- Eugster J
- Eusebi R
- Evangelou I
- Evans D
- Everaerts P
- Everett A
- Evstyukhin S
- Fabbri F
- Fabbri F
- Fabbricatore P
- Fabbro B
- Fabjan C
- Fabozzi F
- Faccioli P
- Fahim A
- Falkiewicz A
- Fanelli C
- Fanfani A
- Fano L
- Fantasia C
- Farrell C
- Fasanella D
- Fassi F
- Faure JL
- Favaro C
- Favart D
- Fay J
- Fedi G
- Fehling D
- Feindt M
- Felcini M
- Feld L
- Ferapontov A
- Ferencek D
- Ferguson T
- Ferguson W
- Fernandez Bedoya C
- Fernandez Menendez J
- Fernandez Perez Tomei TR
- Fernandez Ramos JP
- Fernandez M
- Ferrando A
- Ferri F
- Ferro C
- Field RD
- Finger M
- Finger M
- Fiore L
- Fiorendi S
- Fiori F
- Fisher M
- Fisk I
- Flacher H
- Flanagan W
- Flix J
- Florez C
- Flossdorf A
- Flowers K
- Flucke G
- Flugge G
- Foa L
- Focardi E
- Folgueras S
- Fonseca De Souza S
- Fontaine J-C
- Ford WT
- Forthomme L
- Foudas C
- Fouz MC
- Franci D
- Francis B
- Franzoni G
- Frazier R
- Freeman J
- Freudenreich K
- Friedl M
- Friis E
- Frisch B
- Frosali S
- Frueboes T
- Fruhwirth R
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- Fulcher J
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- Furic IK
- Futyan D
- Gabathuler K
- Gabella W
- Gabusi M
- Gaddi A
- Galanti M
- Gallinaro M
- Gallo E
- Gamsizkan H
- Ganguly S
- Ganjour S
- Gao Y
- Garcia G
- Garcia-Abia P
- Garcia-Bellido A
- Gardner M
- Garrido RGR
- Gartner J
- Gary JW
- Gascon S
- Gasparini F
- Gataullin M
- Gaultney V
- Gauthier L
- Gavrilov V
- Gay APR
- Gaz A
- Gebbert U
- Geenen H
- Geffert P
- Geiser A
- Geisler M
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- Genchev V
- Gennai S
- Georgiou G
- Geralis T
- Gerbaudo D
- Gerber CE
- Gershtein Y
- Gerwig H
- Geurts FJM
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- Giammanco A
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- Giordano D
- Giordano F
- Girgis S
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- Gleyzer SV
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- Guo ZJ
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- Guthoff M
- Gutsche O
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- Hadley NJ
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- Hegner B
- Heidemann C
- Heikkinen A
- Heinrich M
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- Heister A
- Hektor A
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- Henderson C
- Heo SG
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- Heredia-de La Cruz I
- Hermanns T
- Hernandez JM
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- Hofman DJ
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- Hoorani HR
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- Ignatenko M
- Iii RPK
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- Ingram Q
- Innocente V
- Iorio AOM
- Isildak B
- Issah M
- Ivanov A
- Ivanov Y
- Jabeen S
- Jackson J
- Jafari A
- Jain S
- Jain S
- Jain S
- Jang DW
- Janot P
- Janssen X
- Janulis M
- Jarrin EC
- Jarry P
- Jarvis C
- Jarvis M
- Jeitler M
- Jeng GY
- Jenkins M
- Jensen H
- Jeong C
- Jessop C
- Jiang CH
- Jindal M
- Jindal P
- Jindariani S
- Jo HY
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- Johnson KF
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- Josa MI
- Joshi U
- Juillot P
- Jun SY
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- Jussen R
- Justus C
- Kaadze K
- Kachanov V
- Kadastik M
- Kadija K
- Kaestli HC
- Kailas S
- Kalakhety H
- Kalavase P
- Kalinowski A
- Kalogeropoulos A
- Kamel AE
- Kamenev A
- Kamon T
- Kang S
- Kangal EE
- Kanishchev K
- Kao KY
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- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
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- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
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- Akgun B
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- Akin IV
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- Albajar C
- Albayrak EA
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- Alda Junior WL
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- Aliev T
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- Alves GA
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- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
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- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
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- Antunes JR
- Antunovic Z
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- Apollinari G
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- Xiao H
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- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Afanasiev S
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
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- Xiao H
- Xie S
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- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
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- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
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- Ziebarth EB
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- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The azimuthal anisotropy of charged particles in PbPb collisions at
nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS
detector at the LHC over an extended transverse momentum (pt) range up to
approximately 60 GeV. The data cover both the low-pt region associated with
hydrodynamic flow phenomena and the high-pt region where the anisotropies may
reflect the path-length dependence of parton energy loss in the created medium.
The anisotropy parameter (v2) of the particles is extracted by correlating
charged tracks with respect to the event-plane reconstructed by using the
energy deposited in forward-angle calorimeters. For the six bins of collision
centrality studied, spanning the range of 0-60% most-central events, the
observed v2 values are found to first increase with pt, reaching a maximum
around pt = 3 GeV, and then to gradually decrease to almost zero, with the
decline persisting up to at least pt = 40 GeV over the full centrality range
measured.Comment: Replaced with published version. Added journal reference and DO
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
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- Adiguzel A
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- Aguilar-Benitez M
- Aguilo E
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- Ahmad WH
- Ahuja S
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- Akin IV
- Alagoz E
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- Albayrak EA
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- Alcaraz Maestre J
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- Aldaya Martin M
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- Yilmaz Y
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- Zielinski M
- Zito G
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
A search for new physics is performed in events with two same-sign isolated
leptons, hadronic jets, and missing transverse energy in the final state. The
analysis is based on a data sample corresponding to an integrated luminosity of
4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of
7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of
140 increase in integrated luminosity over previously published results. The
observed yields agree with the standard model predictions and thus no evidence
for new physics is found. The observations are used to set upper limits on
possible new physics contributions and to constrain supersymmetric models. To
facilitate the interpretation of the data in a broader range of new physics
scenarios, information on the event selection, detector response, and
efficiencies is provided.Comment: Published in Physical Review Letter
Compressed representation of a partially defined integer function over multiple arguments
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim AA
- Abdullin S
- Abdulsalam A
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- Calderon De La Barca Sanchez M
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- Cepeda M
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- Choudhary BC
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- Christiansen T
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- Chwalek T
- Ciesielski R
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- Cimmino A
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- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
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- Clarida W
- Clement E
- Clerbaux B
- Cline D
- CMS Collaboration
- Coarasa Perez JA
- Cockerill DJA
- Colafranceschi S
- Colaleo A
- Cole JE
- Colino N
- Collard C
- Colling D
- Contardo D
- Conte E
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- Correa Martins Junior M
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- Costantini S
- Costanza F
- Couderc F
- Coughlan JA
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- Cremaldi LM
- Cripps N
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cussans D
- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one
Measurement of jet fragmentation into charged particles in pp and PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
Jet fragmentation in pp and PbPb collisions at a centre-of-mass energy of
2.76 TeV per nucleon pair was studied using data collected with the CMS
detector at the LHC. Fragmentation functions are constructed using
charged-particle tracks with transverse momenta pt > 4 GeV for dijet events
with a leading jet of pt > 100 GeV. The fragmentation functions in PbPb events
are compared to those in pp data as a function of collision centrality, as well
as dijet-pt imbalance. Special emphasis is placed on the most central PbPb
events including dijets with unbalanced momentum, indicative of energy loss of
the hard scattered parent partons. The fragmentation patterns for both the
leading and subleading jets in PbPb collisions agree with those seen in pp data
at 2.76 TeV. The results provide evidence that, despite the large parton energy
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within the jet cone into high-pt particles is not strongly modified in
comparison to that observed for jets in vacuum.Comment: Submitted to the Journal of High Energy Physic
Combined impact of healthy lifestyle factors on colorectal cancer: a large European cohort study
- Author
- A Qasim
- Alessio Naccarati
- AM Leufkens
- Anne Tjønneland
- Antonia Trichopoulou
- AS Whittemore
- Aurelio Barricarte
- Bodil Ohlsson
- C Friedenreich
- C Heidemann
- CA Gonzalez
- D Romaguera
- Dimitrios Trichopoulos
- DJ Harriss
- Domenico Palli
- Dora Romaguera
- E Fieller
- E Riboli
- EA Platz
- EK Wei
- Elio Riboli
- Elisabete Weiderpass
- ES Ford
- FE Ahmed
- FJ van Duijnhoven
- GE Eide
- Genevieve Buckland
- GR Bramer
- Guri Skeie
- H Bas Bueno-de-Mesquita
- H Kirkegaard
- Heather A Ward
- Heiner Boeing
- Ingegerd Johansson
- Ingrid Ljuslinder
- Isabelle Romieu
- JosĂŠ RamĂłn QuirĂłs
- Joyce Kong
- JS Ferlay
- K Aleksandrova
- K Aleksandrova
- K Aleksandrova
- K Hoffmann
- Kathryn E Bradbury
- Kay-Tee Khaw
- KG Alberti
- Kim Overvad
- Krasimira Aleksandrova
- Kristin Benjaminsen Borch
- Kuanrong Li
- Laure Dossus
- Laureen Dartois
- M Jenab
- M Lunn
- M Wiseman
- M Zavoral
- Marc J Gunter
- Maria-Dolores Chirlaque
- Marie-Christine Boutron-Ruault
- MarĂa JosĂŠ SĂĄnchez
- Mazda Jenab
- Miren Dorronsoro
- MP Correa Lima
- N Murphy
- N Murphy
- N Slimani
- Nicholas J Wareham
- OS Miettinen
- P Bruzzi
- P Ferrari
- Pagona Lagiou
- Peter D Siersema
- Petra HM Peeters
- R Kaaks
- Rosario Tumino
- Rudolf Kaaks
- S Bingham
- SA Bingham
- Sabina Rinaldi
- Salvatore Panico
- Sven KnĂźppel
- T Norat
- T Pischon
- T Pischon
- TE Robsahm
- Teresa Norat
- Tobias Pischon
- Ulrika Ericson
- Veronika Fedirko
- Vittorio Krogh
- Z Fu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Background: Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually related to colorectal cancer (CRC) risk; however, little is known about their joint effects. The aim of this study was to develop a healthy lifestyle index (HLI) composed of five potentially modifiable lifestyle factors â healthy weight, physical activity, non-smoking, limited alcohol consumption and a healthy diet, and to explore the association of this index with CRC incidence using data collected within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: In the EPIC cohort, a total of 347,237 men and women, 25- to 70-years old, provided dietary and lifestyle information at study baseline (1992 to 2000). Over a median follow-up time of 12 years, 3,759 incident CRC cases were identified. The association between a HLI and CRC risk was evaluated using Cox proportional hazards regression models and population attributable risks (PARs) have been calculated. Results: After accounting for study centre, age, sex and education, compared with 0 or 1 healthy lifestyle factors, the hazard ratio (HR) for CRC was 0.87 (95% confidence interval (CI): 0.44 to 0.77) for two factors, 0.79 (95% CI: 0.70 to 0.89) for three factors, 0.66 (95% CI: 0.58 to 0.75) for four factors and 0.63 (95% CI: 0.54 to 0.74) for five factors; P-trend <0.0001. The associations were present for both colon and rectal cancers, HRs, 0.61 (95% CI: 0.50 to 0.74; P for trend <0.0001) for colon cancer and 0.68 (95% CI: 0.53 to 0.88; P-trend <0.0001) for rectal cancer, respectively (P-difference by cancer sub-site = 0.10). Overall, 16% of the new CRC cases (22% in men and 11% in women) were attributable to not adhering to a combination of all five healthy lifestyle behaviours included in the index. Conclusions: Combined lifestyle factors are associated with a lower incidence of CRC in European populations characterized by western lifestyles. Prevention strategies considering complex targeting of multiple lifestyle factors may provide practical means for improved CRC prevention. Electronic supplementary material The online version of this article (doi:10.1186/s12916-014-0168-4) contains supplementary material, which is available to authorized users
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