El papel de los hogares sustitutos en el proceso de restablecimiento de los derechos de los niños, niñas y adolescentes en Colombia.

En Colombia existe una amplia legislación con respecto al proceso de restablecimiento de los derechos de los niños, niñas y adolescentes (N.N.A) llevada a la práctica a través de distintos instrumentos, entre ellos los hogares sustitutos, los cuales son una de las formas para adelantar dicho proceso. Sin embargo, estos hogares se ven enfrentados a múltiples problemas, desde los recortes económicos por parte del Estado, hasta una alta demanda de sus servicios en todo el país a raíz de problemas sociales, familiares y de violencia que se viven en los diferentes departamentos, situaciones que dificultan el papel que deben cumplir los hogares sustitutos para el restablecimiento de los derechos de los N.N.A. Por otra parte, es necesario reconocer el papel que desempeña el defensor de familia, el cual es de vital importancia con respecto a las decisiones que se deben tomar frente a los N.N.A relacionados con sus situaciones legales. Así mismo la corresponsabilidad que debe existir entre los diferentes actores sociales como veedores y garantes de los derechos de los N.N.A.Corporación Universitaria Minuto de Dio

El papel de los hogares sustitutos en el proceso de restablecimiento de los derechos de los niños, niñas y adolescentes en Colombia.

En Colombia existe una amplia legislación con respecto al proceso de restablecimiento de los derechos de los niños, niñas y adolescentes (N.N.A) llevada a la práctica a través de distintos instrumentos, entre ellos los hogares sustitutos, los cuales son una de las formas para adelantar dicho proceso. Sin embargo, estos hogares se ven enfrentados a múltiples problemas, desde los recortes económicos por parte del Estado, hasta una alta demanda de sus servicios en todo el país a raíz de problemas sociales, familiares y de violencia que se viven en los diferentes departamentos, situaciones que dificultan el papel que deben cumplir los hogares sustitutos para el restablecimiento de los derechos de los N.N.A. Por otra parte, es necesario reconocer el papel que desempeña el defensor de familia, el cual es de vital importancia con respecto a las decisiones que se deben tomar frente a los N.N.A relacionados con sus situaciones legales. Así mismo la corresponsabilidad que debe existir entre los diferentes actores sociales como veedores y garantes de los derechos de los N.N.A.Corporación Universitaria Minuto de Dio

Memorias que habitan…

El presente artículo de investigación recoge parte del trabajo realizado durante el año 2017 por el semillero “memoria y resistencia” adscrito a la Universidad Católica Luis Amigó, Centro Regional Manizales. El proceso investigativo giró en torno a la pregunta: ¿cómo habitan en nosotros las memorias y las resistencias del conflicto armado en los municipios de Samaná, Salamina, Riosucio y Manizales, durante el periodo comprendido entre 1990 - 2016? Investigación cualitativa de índole documental, entendiendo documento como todas aquellas fuentes producidas por la sociedad (escritas, orales, visuales, audiovisuales, entre otras) que permiten estudiar un fenómeno determinado. Durante el proceso investigativo se identifica que habitar el conflicto armado varía de acuerdo con el nosotros; es así, como hablaremos desde dos nosotros-victimarios-colectivos artísticos- en los que a su vez aparecen distintas formas de habitar. Para el caso de los Victimarios como recuerdo no simbólico, habitó como lucha ideológica o como mal llamado deber cívico. En cuanto a los colectivos artísticos como resistencia y denuncia

La articulación integrada entre academia, investigación y extensión como una experiencia de innovación en educación en Informática para los Cursos de Ingreso de la UNSJ en el marco de SIED UNSJ

En el marco de SIED UNSJ, coordinado por Mg. Rosa Pósito, surgen dos capacitaciones: Curso Taller de Estudiantes Tutores/Tutores Guías/Ayudantes y Curso Taller Docentes de Ingreso para toda la UNSJ, dictadas secuencialmente a niveles de tiempos, donde el resultado obtenido en la primera capacitación es usado como insumo para la segunda capacitación, quienes evaluaron lo realizado en la capacitación anterior. Estas actividades de capacitación académica tienen su innovación y sustento teórico en la articulación de distintos proyectos de investigación que se proponen colaborar en especial con el momento en que los estudiantes aspirantes a ingresar a la UNSJ están decidiendo su carrera por medio de los Cursos de Ingreso que brindan las distintas Facultades y Escuela de Ciencias de la Salud.. El diseño innovador se presenta en el enfoque de meta-modelo pedagógico elegido de aprendizaje inverso/invertido/aula inversa on-line en articulación con el diseño de aula tradicional en un entorno Moodle, de SIED UNSJ mostrando claramente la complementariedad de ambos modelos y en el equipo interdisciplinario de Profesores e Investigadores de UNSJ, de las distintas unidades académicas.Eje: Innovación en Educación Informática.Red de Universidades con Carreras en Informátic

Pulmonary function and radiologic features in survivors of critical COVID-19: a 3-month prospective cohort

© 2021 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/BACKGROUND: More than 20% of hospitalized patients with COVID-19 demonstrate ARDS requiring ICU admission. The long-term respiratory sequelae in such patients remain unclear. RESEARCH QUESTION: What are the major long-term pulmonary sequelae in critical patients who survive COVID-19? STUDY DESIGN AND METHODS: Consecutive patients with COVID-19 requiring ICU admission were recruited and evaluated 3 months after hospitalization discharge. The follow-up comprised symptom and quality of life, anxiety and depression questionnaires, pulmonary function tests, exercise test (6-min walking test [6MWT]), and chest CT imaging. RESULTS: One hundred twenty-five patients admitted to the ICU with ARDS secondary to COVID- 19 were recruited between March and June 2020. At the 3-month follow-up, 62 patients were available for pulmonary evaluation. The most frequent symptoms were dyspnea (46.7%) and cough (34.4%). Eighty-two percent of patients showed a lung diffusing capacity of less than 80%. The median distance in the 6MWT was 400 m (interquartile range, 362-440 m). CT scans showed abnormal results in 70.2% of patients, demonstrating reticular lesions in 49.1% and fibrotic patterns in 21.1%. Patients with more severe alterations on chest CT scan showed worse pulmonary function and presented more degrees of desaturation in the 6MWT. Factors associated with the severity of lung damage on chest CT scan were age and length of invasive mechanical ventilation during the ICU stay. INTERPRETATION: Three months after hospital discharge, pulmonary structural abnormalities and functional impairment are highly prevalent in patients with ARDS secondary to COVID- 19 who required an ICU stay. Pulmonary evaluation should be considered for all critical COVID-19 survivors 3 months after discharge.This study was supported in part by the Instituto de Salud Carlos III [Grant CIBERESUCICOVID, COV20/00110] and was cofunded by European Regional Development Funds, “Una manera de hacer Europa.” D. d. G.-C. has received financial support from the Instituto de Salud Carlos III [Grant Miguel Servet 2020: CP20/00041], co-funded by the European Social Fund “Investing in Your Future.” L. P. acknowledges receiving financial support from the Ministry of Science, Innovation and Universities for the Training of University Lecturers (FPU19 / 03526).Peer ReviewedPostprint (author's final draft

Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

The authors wish to make the following corrections to this paper [...]

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery

Analysis of the common genetic component of large-vessel vasculitides through a meta- Immunochip strategy

Giant cell arteritis (GCA) and Takayasu's arteritis (TAK) are major forms of large-vessel vasculitis (LVV) that share clinical features. To evaluate their genetic similarities, we analysed Immunochip genotyping data from 1,434 LVV patients and 3,814 unaffected controls. Genetic pleiotropy was also estimated. The HLA region harboured the main disease-specific associations. GCA was mostly associated with class II genes (HLA-DRB1/HLA-DQA1) whereas TAK was mostly associated with class I genes (HLA-B/MICA). Both the statistical significance and effect size of the HLA signals were considerably reduced in the cross-disease meta-analysis in comparison with the analysis of GCA and TAK separately. Consequently, no significant genetic correlation between these two diseases was observed when HLA variants were tested. Outside the HLA region, only one polymorphism located nearby the IL12B gene surpassed the study-wide significance threshold in the meta-analysis of the discovery datasets (rs755374, P?=?7.54E-07; ORGCA?=?1.19, ORTAK?=?1.50). This marker was confirmed as novel GCA risk factor using four additional cohorts (PGCA?=?5.52E-04, ORGCA?=?1.16). Taken together, our results provide evidence of strong genetic differences between GCA and TAK in the HLA. Outside this region, common susceptibility factors were suggested, especially within the IL12B locus

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016