1,230 research outputs found

    Quantum Effects of the Conformal Anomaly in a 2D Model of Gravitational Collapse

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    The macroscopic effects of the quantum conformal anomaly are evaluated in a simplified two-dimensional model of gravitational collapse. The effective action and stress tensor of the anomaly can be expressed in a local quadratic form by the introduction of a scalar conformalon field which satisfies a linear wave equation. A wide class of non-vacuum initial state conditions is generated by different solutions of this equation. An interesting subclass of solutions corresponds to initial states that give rise to an arbitrarily large semi-classical stress tensor on the future horizon of the black hole formed in classical collapse. These lead to modification and suppression of Hawking radiation at late times after the collapse, and potentially large backreaction effects on the horizon scale due to the conformal anomaly. The probability of non-vacuum initial conditions large enough to produce these effects is estimated from the Gaussian vacuum wave functional in the Schrodinger representation and shown to be of order 1. These results indicate that quantum effects of the conformal anomaly in non-vacuum states are relevant for gravitational collapse in the effective theory of gravity in four dimensions as well.Comment: 40 pages, 5 figure

    Rheumatoid arthritis patient antibodies highly recognize IL-2 in the immune response pathway involving IRF5 and EBV antigens

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    Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by a progressive joint damage due to largely unknown environmental factors acting in concert with risk alleles conferring genetic susceptibility. A major role has been attributed to viral infections that include past contacts with Epstein-Barr virus (EBV) and, more recently, to non-protein coding sequences of human endogenous retrovirus K (HERV-K) integrated in the human genome. Molecular mimicry between viral and self proteins is supposed to cause the loss of immune tolerance in predisposed hosts. There are evidences that anti-IL-2 antibodies (Abs) are present in subjects affected by autoimmune diseases and may be responsible for alterations in regulatory T cell responses. In this study, we evaluated the levels of Abs against IL-2, viral epitopes and interferon regulatory factor 5 (IRF5) in 140 RA patients and 137 healthy controls (HCs). Ab reactivity reached the highest levels for IRF5, EBV and IL-2 (56%, 44% and 39%, respectively) in RA with significantly lower values among HCs (7–9%, p <  0.0001), which suggests a possible cross-reaction between IRF5/EBV homologous antigens and shifts in T cell balance disrupted by anti-IL-2 Abs

    Dynamical non-axisymmetric instabilities in rotating relativistic stars

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    We present new results on dynamical instabilities in rapidly rotating neutron-stars. In particular, using numerical simulations in full General Relativity, we analyse the effects that the stellar compactness has on the threshold for the onset of the dynamical bar-mode instability, as well as on the appearance of other dynamical instabilities. By using an extrapolation technique developed and tested in our previous study [1], we explicitly determine the threshold for a wide range of compactnesses using four sequences of models of constant baryonic mass comprising a total of 59 stellar models. Our calculation of the threshold is in good agreement with the Newtonian prediction and improves the previous post-Newtonian estimates. In addition, we find that for stars with sufficiently large mass and compactness, the m=3 deformation is the fastest growing one. For all of the models considered, the non-axisymmetric instability is suppressed on a dynamical timescale with an m=1 deformation dominating the final stages of the instability. These results, together with those presented in [1], suggest that an m=1 deformation represents a general and late-time feature of non-axisymmetric dynamical instabilities both in full General Relativity and in Newtonian gravity.Comment: To appear on CQG, NFNR special issue. 16 pages, 5 color figures, movies from http://www.fis.unipr.it/numrel/BarMode/ResearchBarMode.htm

    Critical slowing down of topological modes

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    We investigate the critical slowing down of the topological modes using local updating algorithms in lattice 2-d CP^(N-1) models. We show that the topological modes experience a critical slowing down that is much more severe than the one of the quasi-Gaussian modes relevant to the magnetic susceptibility, which is characterized by τmagξz\tau_{\rm mag} \sim \xi^z with z2z\approx 2. We argue that this may be a general feature of Monte Carlo simulations of lattice theories with non-trivial topological properties, such as QCD, as also suggested by recent Monte Carlo simulations of 4-d SU(N) lattice gauge theories.Comment: 16 pages, 4 figure

    Accurate simulations of the dynamical bar-mode instability in full General Relativity

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    We present accurate simulations of the dynamical bar-mode instability in full General Relativity focussing on two aspects which have not been investigated in detail in the past. Namely, on the persistence of the bar deformation once the instability has reached its saturation and on the precise determination of the threshold for the onset of the instability in terms of the parameter β=T/W\beta={T}/{|W|}. We find that generic nonlinear mode-coupling effects appear during the development of the instability and these can severely limit the persistence of the bar deformation and eventually suppress the instability. In addition, we observe the dynamics of the instability to be strongly influenced by the value β\beta and on its separation from the critical value βc\beta_c marking the onset of the instability. We discuss the impact these results have on the detection of gravitational waves from this process and provide evidence that the classical perturbative analysis of the bar-mode instability for Newtonian and incompressible Maclaurin spheroids remains qualitatively valid and accurate also in full General Relativity.Comment: RevTeX4, 23 pages, 19 figures. Version in prin

    An embedding technique to determine ττ backgrounds in proton-proton collision data

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    An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe

    Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

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    Measurement of the Splitting Function in &ITpp &ITand Pb-Pb Collisions at root&ITsNN&IT=5.02 TeV

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    Data from heavy ion collisions suggest that the evolution of a parton shower is modified by interactions with the color charges in the dense partonic medium created in these collisions, but it is not known where in the shower evolution the modifications occur. The momentum ratio of the two leading partons, resolved as subjets, provides information about the parton shower evolution. This substructure observable, known as the splitting function, reflects the process of a parton splitting into two other partons and has been measured for jets with transverse momentum between 140 and 500 GeV, in pp and PbPb collisions at a center-of-mass energy of 5.02 TeV per nucleon pair. In central PbPb collisions, the splitting function indicates a more unbalanced momentum ratio, compared to peripheral PbPb and pp collisions.. The measurements are compared to various predictions from event generators and analytical calculations.Peer reviewe
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