272 research outputs found
Observation of a Coherence Length Effect in Exclusive Rho^0 Electroproduction
Exclusive incoherent electroproduction of the rho^0(770) meson from 1H, 2H,
3He, and 14N targets has been studied by the HERMES experiment at squared
four-momentum transfer Q**2>0.4 GeV**2 and positron energy loss nu from 9 to 20
GeV. The ratio of the 14N to 1H cross sections per nucleon, known as the
nuclear transparency, was found to decrease with increasing coherence length of
quark-antiquark fluctuations of the virtual photon. The data provide clear
evidence of the interaction of the quark- antiquark fluctuations with the
nuclear medium.Comment: RevTeX, 5 pages, 3 figure
Measurement of the Neutron Spin Structure Function with a Polarized ^3He Target
Results are reported from the HERMES experiment at HERA on a measurement of
the neutron spin structure function in deep inelastic scattering
using 27.5 GeV longitudinally polarized positrons incident on a polarized
He internal gas target. The data cover the kinematic range
and . The integral evaluated at a fixed of is . Assuming Regge behavior at low , the first
moment is .Comment: 4 pages TEX, text available at
http://www.krl.caltech.edu/preprints/OAP.htm
Healthcare system engagement and algorithm-identified cancer incidence following initiation of a new medication
Purpose: Implausibly high algorithm-identified cancer incidence within a new user study after medication initiation may result from increased healthcare utilization (HU) around initiation (“catch-up care”) that increases diagnostic opportunity. Understanding the relationships between HU prior to and around initiation and subsequent cancer rates and timing is important to avoiding protopathic bias. Methods: We identified a cohort of 417 458 Medicare beneficiaries (2007–2014) aged ≥66 initiating an antihypertensive (AHT) after ≥180 days of non-use. Initiators were stratified into groups of 0, 1, 2–3, and ≥4 outpatient visits (OV) 60–360 days before initiation. We calculated algorithm-identified colorectal cancer (aiCRC) rates stratified by OVs and time since AHT initiation: (0–90, 91–180, 181–365, 366–730, and 731+ days). We summarized HU -360/+60 days around AHT initiation by aiCRC timing: (0–29, 30–89, 90–179, and ≥180 days). Results: AiCRC incidence (311 per 100 000 overall) peaked in the first 0–90 days, was inversely associated with HU before initiation, and stabilized ≥180 days after AHT initiation. Catch-up care was greatest among persons with aiCRCs identified <30 days in follow-up. Catch-up care magnitude decreased as time to the aiCRC date increased, with aiCRCs identified ≥180 days after AHT initiation exhibiting similar HU compared with the full cohort. Conclusion: Lower HU before—and increased HU around AHT initiation—seem to drive excess short-term aiCRC incidence. Person-time and case accrual should only begin when incidence stabilizes. When comparison groups within a study differ by HU, outcome-detection bias may exist. Similar observations may exist in other settings when typical HU is delayed (e.g., cancer screening during SARS-CoV-2)
Data Transformation and Semantic Log Purging for Process Mining
Existing process mining approaches are able to tolerate a certain degree of noise in the process log. However, processes that contain infrequent paths, multiple (nested) parallel branches, or have been changed in an ad-hoc manner,
still pose major challenges. For such cases, process mining typically returns "spaghetti-models", that are hardly usable even as a starting point for process (re-)design. In this paper, we address these challenges by introducing data transformation and pre-processing steps that improve and ensure the quality of mined models for existing process mining approaches. We propose the concept of semantic log purging, the cleaning of logs based on domain specific
constraints utilizing semantic knowledge which typically complements processes. Furthermore we demonstrate the feasibility and effectiveness of the approach based
on a case study in the higher education domain. We think that semantic log purging will enable process mining to yield better results, thus giving process (re-)designers a valuable tool
Measurement of the mass difference between top quark and antiquark in pp collisions at root s=8 TeV
Peer reviewe
Assessment of completeness of reporting in intervention studies using livestock: an example from pain mitigation interventions in neonatal piglets
Accurate and complete reporting of study methods, results and interpretation are essential components for any scientific process, allowing end-users to evaluate the internal and external validity of a study. When animals are used in research, excellence in reporting is expected as a matter of continued ethical acceptability of animal use in the sciences. Our primary objective was to assess completeness of reporting for a series of studies relevant to mitigation of pain in neonatal piglets undergoing routine management procedures. Our second objective was to illustrate how authors can report the items in the Reporting guidElines For randomized controLled trials for livEstoCk and food safety (REFLECT) statement using examples from the animal welfare science literature. A total of 52 studies from 40 articles were evaluated using a modified REFLECT statement. No single study reported all REFLECT checklist items. Seven studies reported specific objectives with testable hypotheses. Six studies identified primary or secondary outcomes. Randomization and blinding were considered to be partially reported in 21 and 18 studies, respectively. No studies reported the rationale for sample sizes. Several studies failed to report key design features such as units for measurement, means, standard deviations, standard errors for continuous outcomes or comparative characteristics for categorical outcomes expressed as either rates or proportions. In the discipline of animal welfare science, authors, reviewers and editors are encouraged to use available reporting guidelines to ensure that scientific methods and results are adequately described and free of misrepresentations and inaccuracies. Complete and accurate reporting increases the ability to apply the results of studies to the decision-making process and prevent wastage of financial and animal resources
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