Análisis estructural 3D de los invernaderos multitunel del sudeste de España. Elementos verticales

Este trabajo analiza la capacidad estructural de los elementos verticales que componen el pórtico resistente más limitativo de la variante de invernadero multitúnel más utilizada en el sudeste de España. Se estudia la influencia de la longitud y anchura del invernadero en la distribución de tensiones que se produce en dichos elementos. Se ha realizado un modelo tridimensional de elementos finitos con el programa ROBOT MILLENNIUM en su versión 20.1 en el que se ha representado la estructura de barras que conforma el invernadero. Se han analizado los resultados de tensiones normales máximas de 16 estructuras con geometría de túnel similar, pero de diferente anchura y longitud, de tal forma que la superficie en planta oscila entre los 600 m 2 y los 38.400 m 2 . El cálculo de las acciones existentes sobre los invernaderos se ha realizado según la norma UNE-EN 13031-1. Los resultados numéricos obtenidos han sido estudiados para determinar la influencia de las dimensiones del invernadero en la distribución de tensiones. Aunque se observan significativas reducciones en las tensiones con la adición de túneles, no se puede generalizar la influencia del aumento de las dimensiones del invernadero en los cambios tensionales del mismo. Los resultados obtenidos se consideran de gran utilidad para la optimización de las estructuras de los invernaderos multitúnel así como para garantizar la seguridad mecánica de las misma

SHARDS: A global view of the star formation activity at z∼ 0.84 and z∼ 1.23

et al.In this paper, we present a comprehensive analysis of star-forming galaxies (SFGs) at intermediate redshifts (z ∼ 1). We combine the ultra-deep optical spectro-photometric data from the Survey for High-z Absorption Red and Dead Sources (SHARDS) with deep UV-to-FIR observations in the GOODS-N field. Exploiting two of the 25 SHARDS medium-band filters, F687W17 and F823W17, we select [O ii] emission line galaxies at z ∼ 0.84 and z ∼ 1.23 and characterize their physical properties. Their rest-frame equivalent widths (EW([O ii])), line fluxes, luminosities, star formation rates (SFRs), and dust attenuation properties are investigated. The evolution of EW([O ii]) closely follows the SFR density evolution of the universe, with a trend of EW([O ii]) (1 + z) up to redshift z ≃ 1, followed by a possible flattening. The SF properties of the galaxies selected on the basis of their [O ii] emission are compared with complementary samples of SFGs selected by their MIR and FIR emission, and also with a general mass-selected sample of galaxies at the same redshifts. We demonstrate observationally that the UVJ diagram (or, similarly, a cut in the specific SFR) is only partially able to distinguish the quiescent galaxies from the SFGs. The SFR-M relation is investigated for the different samples, yielding a logarithmic slope ∼1, in good agreement with previous results. The dust attenuations derived from different SFR indicators (UV(1600), UV(2800), [O ii], IR) are compared and show clear trends with respect to both the stellar mass and total SFR, with more massive and highly star-forming galaxies being affected by stronger dust attenuation.The work of A.C. is supported by the STARFORM Sinergia Project funded by the Swiss National Science Foundation, and also benefited from a MERAC Funding and Travel Award. P.G.P.-G. acknowledges support from the Spanish Programa Nacional de Astronomía y Astrofísica under grants AYA2012-31277. A.V.G. acknowledges support from the ERC via an Advanced Grant under grant agreement no. 321323-NEOGAL. N.C. acknowledges support from the Spanish Ministry of Economy and Competitiveness under grant AYA2013-46724-P. A.A.H. and A.H.C. acknowledge financial support from the Spanish Ministry of Economy and Competitiveness through grant AYA2012-31447, which is partly funded by the FEDER program. A.J.C. is a Ramón y Cajal Fellow of the Spanish Ministry of Science and Innovation and acknowledges financial support from the Spanish Ministry of Economy and Competitiveness through grant AYA2012-30789, partly funded by the FEDER program.Peer Reviewe

A strongly first order electroweak phase transition from strong symmetry-breaking interactions

We argue that a strongly first order electroweak phase transition is natural in the presence of strong symmetry-breaking interactions, such as technicolor. We demonstrate this using an effective linear scalar theory of the symmetry-breaking sector.Comment: LaTex, 15 pages, 3 figures in EPS format. Phys. Rev. D approved Typographically Correct version, minor grammatical change

Complementarity of the CERN Large Hadron Collider and the e+e−e^+e^- International Linear Collider

The next-generation high-energy facilities, the CERN Large Hadron Collider (LHC) and the prospective $e^+e^-$ International Linear Collider (ILC), are expected to unravel new structures of matter and forces from the electroweak scale to the TeV scale. In this report we review the complementary role of LHC and ILC in drawing a comprehensive and high-precision picture of the mechanism breaking the electroweak symmetries and generating mass, and the unification of forces in the frame of supersymmetry.Comment: 14 pages, 17 figures, to be published in "Supersymmetry on the Eve of the LHC", a special volume of European Physical Journal C, Particles and Fields (EPJC) in memory of Julius Wes

Action on the social determinants for advancing health equity in the time of COVID-19: perspectives of actors engaged in a WHO Special Initiative.

Since the 2008 publication of the reports of the Commission on Social Determinants of Health and its nine knowledge networks, substantial research has been undertaken to document and describe health inequities. The COVID-19 pandemic has underscored the need for a deeper understanding of, and broader action on, the social determinants of health. Building on this unique and critical opportunity, the World Health Organization is steering a multi-country Initiative to reduce health inequities through an action-learning process in 'Pathfinder' countries. The Initiative aims to develop replicable and reliable models and practices that can be adopted by WHO offices and UN staff to address the social determinants of health to advance health equity. This paper provides an overview of the Initiative by describing its broad theory of change and work undertaken in three regions and six Pathfinder countries in its first year-and-a-half. Participants engaged in the Initiative describe results of early country dialogues and promising entry points for implementation that involve model, network and capacity building. The insights communicated through this note from the field will be of interest for others aiming to advance health equity through taking action on the social determinants of health, in particular as regards structural determinants

Blood pressure-lowering effects of nifedipine/candesartan combinations in high-risk individuals: Subgroup analysis of the DISTINCT randomised trial

The DISTINCT study (reDefining Intervention with Studies Testing Innovative Nifedipine GITS - Candesartan Therapy) investigated the efficacy and safety of nifedipine GITS/candesartan cilexetil combinations vs respective monotherapies and placebo in patients with hypertension. This descriptive sub-analysis examined blood pressure (BP)-lowering effects in high-risk participants, including those with renal impairment (estimated glomerular filtration rate<90 ml min-1, n=422), type 2 diabetes mellitus (n=202), hypercholesterolaemia (n=206) and cardiovascular (CV) risk factors (n=971), as well as the impact of gender, age and body mass index (BMI). Participants with grade I/II hypertension were randomised to treatment with nifedipine GITS (N) 20, 30, 60 mg and/or candesartan cilexetil (C) 4, 8, 16, 32 mg or placebo for 8 weeks. Mean systolic BP and diastolic BP reductions after treatment in high-risk participants were greater, overall, with N/C combinations vs respective monotherapies or placebo, with indicators of a dose-response effect. Highest rates of BP control (ESH/ESC 2013 guideline criteria) were also achieved with highest doses of N/C combinations in each high-risk subgroup. The benefits of combination therapy vs monotherapy were additionally observed in patient subgroups categorised by gender, age or BMI. All high-risk participants reported fewer vasodilatory adverse events in the pooled N/C combination therapy than the N monotherapy group. In conclusion, consistent with the DISTINCT main study outcomes, high-risk participants showed greater reductions in BP and higher control rates with N/C combinations compared with respective monotherapies and lesser vasodilatory side-effects compared with N monotherapy

Natural History of MYH7-Related Dilated Cardiomyopathy

BACKGROUND Variants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to 5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and natural history of MYH7-related DCM are poorly described. OBJECTIVES We sought to determine the phenotype and prognosis of MYH7-related DCM. We also evaluated the influence of variant location on phenotypic expression. METHODS We studied clinical data from 147 individuals with DCM-causing MYH7 variants (47.6% female; 35.6 +/- 19.2 years) recruited from 29 international centers. RESULTS At initial evaluation, 106 (72.1%) patients had DCM (left ventricular ejection fraction: 34.5% +/- 11.7%). Median follow-up was 4.5 years (IQR: 1.7-8.0 years), and 23.7% of carriers who were initially phenotype-negative developed DCM. Phenotypic expression by 40 and 60 years was 46% and 88%, respectively, with 18 patients (16%) first diagnosed at <18 years of age. Thirty-six percent of patients with DCM met imaging criteria for LV noncompaction. During follow-up, 28% showed left ventricular reverse remodeling. Incidence of adverse cardiac events among patients with DCM at 5 years was 11.6%, with 5 (4.6%) deaths caused by end-stage heart failure (ESHF) and 5 patients (4.6%) requiring heart transplantation. The major ventricular arrhythmia rate was low (1.0% and 2.1% at 5 years in patients with DCM and in those with LVEF of <= 35%, respectively). ESHF and major ventricular arrhythmia were significantly lower compared with LMNA-related DCM and similar to DCM caused by TTN truncating variants. CONCLUSIONS MYH7-related DCM is characterized by early age of onset, high phenotypic expression, low left ventricular reverse remodeling, and frequent progression to ESHF. Heart failure complications predominate over ventricular arrhythmias, which are rare. (C) 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation

Search for leptophobic Z ' bosons decaying into four-lepton final states in proton-proton collisions at root s=8 TeV

Peer reviewe