167 research outputs found
Breaking the Cycle of Pain In Diabetic Peripheral Neuropathy
An attitude of helplessness pervades both patients and health professionals when dealing with the problems of dia betic peripheral neuropathy. Those afflicted are often over whelmed by the pain and find themselves unable to fulfill the daily requirements of their diabetes regimen. The in consistencies in amounts and timing of meals, levels of ac tivity, and scheduling of insulin injections can result in hyperglycemia, a state that has been found to correlate strongly with the occurrence of nerve damage. Thus the pain perpetrates itself. For the health professional, having to confront this devastating pain without objective factors to assess and few scientific treatment measures to offer con tributes to a sense of inadequacy and ignorance. It is fre quently assumed that "nothing can be done." In reality, health professionals do have something to offer the person suffering from this condition. First, they can provide infor mation about the relationship between control and compli cations, and explain the need for the patient to change those behaviors that may be perpetuating the pain. Sec ond, and most importantly, health professionals can con vey support and confidence, without which many patients will be unable to make the changes in their behavior neces sary to resolve their pain.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68854/2/10.1177_014572178501100103.pd
Probing Primordial Non-Gaussianity with Large-Scale Structure
We consider primordial non-Gaussianity due to quadratic corrections in the
gravitational potential parametrized by a non-linear coupling parameter fnl. We
study constraints on fnl from measurements of the galaxy bispectrum in redshift
surveys. Using estimates for idealized survey geometries of the 2dF and SDSS
surveys and realistic ones from SDSS mock catalogs, we show that it is possible
to probe |fnl|~100, after marginalization over bias parameters. We apply our
methods to the galaxy bispectrum measured from the PSCz survey, and obtain a
2sigma-constraint |fnl|< 1800. We estimate that an all sky redshift survey up
to z~1 can probe |fnl|~1. We also consider the use of cluster abundance to
constrain fnl and find that in order to be sensitive to |fnl|~100, cluster
masses need to be determined with an accuracy of a few percent, assuming
perfect knowledge of the mass function and cosmological parameters.Comment: 15 pages, 7 figure
[Accepted Manuscript] Smartphone tool to collect repeated 24 h dietary recall data in Nepal.
To outline the development of a smartphone-based tool to collect thrice-repeated 24 h dietary recall data in rural Nepal, and to describe energy intakes, common errors and researchers' experiences using the tool.
We designed a novel tool to collect multi-pass 24 h dietary recalls in rural Nepal by combining the use of a CommCare questionnaire on smartphones, a paper form, a QR (quick response)-coded list of foods and a photographic atlas of portion sizes. Twenty interviewers collected dietary data on three non-consecutive days per respondent, with three respondents per household. Intakes were converted into nutrients using databases on nutritional composition of foods, recipes and portion sizes.
Dhanusha and Mahottari districts, Nepal.
Pregnant women, their mothers-in-law and male household heads. Energy intakes assessed in 150 households; data corrections and our experiences reported from 805 households and 6765 individual recalls.
Dietary intake estimates gave plausible values, with male household heads appearing to have higher energy intakes (median (25th-75th centile): 12 079 (9293-14 108) kJ/d) than female members (8979 (7234-11 042) kJ/d for pregnant women). Manual editing of data was required when interviewers mistook portions for food codes and for coding items not on the food list. Smartphones enabled quick monitoring of data and interviewer performance, but we initially faced technical challenges with CommCare forms crashing.
With sufficient time dedicated to development and pre-testing, this novel smartphone-based tool provides a useful method to collect data. Future work is needed to further validate this tool and adapt it for other contexts
Forward jet production in deep inelastic ep scattering and low-x parton dynamics at HERA
Differential inclusive jet cross sections in neutral current deep inelastic
ep scattering have been measured with the ZEUS detector. Three phase-space
regions have been selected in order to study parton dynamics where the effects
of BFKL evolution might be present. The measurements have been compared to the
predictions of leading-logarithm parton shower Monte Carlo models and
fixed-order perturbative QCD calculations. In the forward region, QCD
calculations at order alpha_s^1 underestimate the data up to an order of
magnitude at low x. An improved description of the data in this region is
obtained by including QCD corrections at order alpha_s^2, which account for the
lowest-order t-channel gluon-exchange diagrams, highlighting the importance of
such terms in parton dynamics at low x.Comment: 25 pages, 4 figure
Time-integrated luminosity recorded by the BABAR detector at the PEP-II e+e- collider
This article is the Preprint version of the final published artcile which can be accessed at the link below.We describe a measurement of the time-integrated luminosity of the data collected by the BABAR experiment at the PEP-II asymmetric-energy e+e- collider at the Ï(4S), Ï(3S), and Ï(2S) resonances and in a continuum region below each resonance. We measure the time-integrated luminosity by counting e+e-âe+e- and (for the Ï(4S) only) e+e-âÎŒ+ÎŒ- candidate events, allowing additional photons in the final state. We use data-corrected simulation to determine the cross-sections and reconstruction efficiencies for these processes, as well as the major backgrounds. Due to the large cross-sections of e+e-âe+e- and e+e-âÎŒ+ÎŒ-, the statistical uncertainties of the measurement are substantially smaller than the systematic uncertainties. The dominant systematic uncertainties are due to observed differences between data and simulation, as well as uncertainties on the cross-sections. For data collected on the Ï(3S) and Ï(2S) resonances, an additional uncertainty arises due to Ïâe+e-X background. For data collected off the Ï resonances, we estimate an additional uncertainty due to time dependent efficiency variations, which can affect the short off-resonance runs. The relative uncertainties on the luminosities of the on-resonance (off-resonance) samples are 0.43% (0.43%) for the Ï(4S), 0.58% (0.72%) for the Ï(3S), and 0.68% (0.88%) for the Ï(2S).This work is supported by the US Department of Energy and National Science Foundation, the Natural Sciences and Engineering Research Council (Canada), the Commissariat Ă lâEnergie Atomique and Institut National de Physique NuclĂ©aire et de Physiquedes Particules (France), the Bundesministerium fĂŒr Bildung und Forschung and Deutsche Forschungsgemeinschaft (Germany), the Istituto Nazionale di Fisica Nucleare (Italy), the Foundation for Fundamental Research on Matter (The Netherlands), the Research Council of Norway, the Ministry of Education and Science of the Russian Federation, Ministerio de Ciencia e InnovaciĂłn (Spain), and the Science and Technology Facilities Council (United Kingdom). Individuals have received support from the Marie-Curie IEF program (European Union) and the A.P. Sloan Foundation (USA)
Measurement of (anti)deuteron and (anti)proton production in DIS at HERA
The first observation of (anti)deuterons in deep inelastic scattering at HERA
has been made with the ZEUS detector at a centre-of-mass energy of 300--318 GeV
using an integrated luminosity of 120 pb-1. The measurement was performed in
the central rapidity region for transverse momentum per unit of mass in the
range 0.3<p_T/M<0.7. The particle rates have been extracted and interpreted in
terms of the coalescence model. The (anti)deuteron production yield is smaller
than the (anti)proton yield by approximately three orders of magnitude,
consistent with the world measurements.Comment: 26 pages, 9 figures, 5 tables, submitted to Nucl. Phys.
Multifunctional Magnetic-fluorescent Nanocomposites for Biomedical Applications
Nanotechnology is a fast-growing area, involving the fabrication and use of nano-sized materials and devices. Various nanocomposite materials play a number of important roles in modern science and technology. Magnetic and fluorescent inorganic nanoparticles are of particular importance due to their broad range of potential applications. It is expected that the combination of magnetic and fluorescent properties in one nanocomposite would enable the engineering of unique multifunctional nanoscale devices, which could be manipulated using external magnetic fields. The aim of this review is to present an overview of bimodal âtwo-in-oneâ magnetic-fluorescent nanocomposite materials which combine both magnetic and fluorescent properties in one entity, in particular those with potential applications in biotechnology and nanomedicine. There is a great necessity for the development of these multifunctional nanocomposites, but there are some difficulties and challenges to overcome in their fabrication such as quenching of the fluorescent entity by the magnetic core. Fluorescent-magnetic nanocomposites include a variety of materials including silica-based, dye-functionalised magnetic nanoparticles and quantum dots-magnetic nanoparticle composites. The classification and main synthesis strategies, along with approaches for the fabrication of fluorescent-magnetic nanocomposites, are considered. The current and potential biomedical uses, including biological imaging, cell tracking, magnetic bioseparation, nanomedicine and bio- and chemo-sensoring, of magnetic-fluorescent nanocomposites are also discussed
Clustering of dark matter tracers: generalizing bias for the coming era of precision LSS
On very large scales, density fluctuations in the Universe are small,
suggesting a perturbative model for large-scale clustering of galaxies (or
other dark matter tracers), in which the galaxy density is written as a Taylor
series in the local mass density, delta, with the unknown coefficients in the
series treated as free "bias" parameters. We extend this model to include
dependence of the galaxy density on the local values of nabla_i nabla_j phi and
nabla_i v_j, where phi is the potential and v is the peculiar velocity. We show
that only two new free parameters are needed to model the power spectrum and
bispectrum up to 4th order in the initial density perturbations, once symmetry
considerations and equivalences between possible terms are accounted for. One
of the new parameters is a bias multiplying s_ij s_ji, where s_ij=[nabla_i
nabla_j \nabla^-2 - 1/3 delta^K_ij] delta. The other multiplies s_ij t_ji,
where t_ij=[nabla_i nabla_j nabla^-2 - 1/3 delta^K_ij](theta-delta), with
theta=-(a H dlnD/dlna)^-1 nabla_i v_i. (There are other, observationally
equivalent, ways to write the two terms, e.g., using theta-delta instead of
s_ij s_ji.) We show how short-range (non-gravitational) non-locality can be
included through a controlled series of higher derivative terms, starting with
R^2 nabla^2 delta, where R is the scale of non-locality (this term will be a
small correction as long as k^2 R^2 is small, where k is the observed
wavenumber). We suggest that there will be much more information in future huge
redshift surveys in the range of scales where beyond-linear perturbation theory
is both necessary and sufficient than in the fully linear regime.Comment: 24 pg., 5 fi
Observation of the baryonic decay B \uaf 0 \u2192 \u39bc+ p \uaf K-K+
We report the observation of the baryonic decay B\uaf0\u2192\u39bc+p\uafK-K+ using a data sample of 471
7106 BB\uaf pairs produced in e+e- annihilations at s=10.58GeV. This data sample was recorded with the BABAR detector at the PEP-II storage ring at SLAC. We find B(B\uaf0\u2192\u39bc+p\uafK-K+)=(2.5\ub10.4(stat)\ub10.2(syst)\ub10.6B(\u39bc+))
710-5, where the uncertainties are statistical, systematic, and due to the uncertainty of the \u39bc+\u2192pK-\u3c0+ branching fraction, respectively. The result has a significance corresponding to 5.0 standard deviations, including all uncertainties. For the resonant decay B\uaf0\u2192\u39bc+p\uaf\u3c6, we determine the upper limit B(B\uaf0\u2192\u39bc+p\uaf\u3c6)<1.2
710-5 at 90% confidence level
Deep inelastic inclusive and diffractive scattering at values from 25 to 320 GeV with the ZEUS forward plug calorimeter
Deep inelastic scattering and its diffractive component, , have been studied at HERA with the ZEUS
detector using an integrated luminosity of 52.4 pb. The method has
been used to extract the diffractive contribution. A wide range in the
centre-of-mass energy (37 -- 245 GeV), photon virtuality (20 -- 450
GeV) and mass (0.28 -- 35 GeV) is covered. The diffractive cross
section for GeV rises strongly with , the rise becoming
steeper as increases. The data are also presented in terms of the
diffractive structure function, , of the proton. For fixed
and fixed , \xpom F^{\rm D(3)}_2 shows a strong rise as \xpom \to
0, where \xpom is the fraction of the proton momentum carried by the
Pomeron. For Bjorken-, \xpom F^{\rm D(3)}_2 shows
positive scaling violations, while for
negative scaling violations are observed. The diffractive structure function is
compatible with being leading twist. The data show that Regge factorisation is
broken.Comment: 89 pages, 27 figure
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