Archaeological Landscapes during the 10–8 ka Lake Stanley Lowstand on the Alpena‐Amberley Ridge, Lake Huron

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/136243/1/gea21590.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136243/2/gea21590_am.pd

Associations of autozygosity with a broad range of human phenotypes

In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. Here, using genomic inbreeding coefficients (FROH) for >1.4 million individuals, we show that FROH is significantly associated (p < 0.0005) with apparently deleterious changes in 32 out of 100 traits analysed. These changes are associated with runs of homozygosity (ROH), but not with common variant homozygosity, suggesting that genetic variants associated with inbreeding depression are predominantly rare. The effect on fertility is striking: FROH equivalent to the offspring of first cousins is associated with a 55% decrease [95% CI 44–66%] in the odds of having children. Finally, the effects of FROH are confirmed within full-sibling pairs, where the variation in FROH is independent of all environmental confounding

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits : A Multi-Ethnic Meta-Analysis of 45,891 Individuals

J. Kaprio, S. Ripatti ja M.-L. Lokki työryhmien jäseniä.Peer reviewe

CAPITAL FORMATION IN AUSTRALIAN AGRICULTURE: DISCUSSION

Agricultural Finance,

The production of single crystals of AgI

A method is described for growing crystals of hexagonal silver iodide from a solution of AgI in concentrated aqueous KI solution. This method relies on convective circulation of the growth solution between two chambers held at different temperatures and produces large single crystals much more rapidly than previous methods. A successful method of transforming these crystals to the high temperature cubic phase is also described