“Interpretación patogénica de los tumores de mieloplaxias de los tendones”: Conferencia inaugural del Instituto Médico de Posgraduados de la Casa de Salud Valdecilla (1930) impartida por el Dr. González- Aguilar.

RESUMEN: La Casa de Salud Valdecilla se inaugura oficialmente en octubre de 1929. Uno de sus vectores de desarrollo era la investigación. El Instituto Médico de Posgraduados, dedicado a investigación, se inaugura en enero de 1930. El acto de inauguración tuvo una figura destacada: el Dr. González-Aguilar, Profesor Jefe de la Clínica de Huesos y Articulaciones de la Casa de Salud Valdecilla. Su conferencia inaugural, que ahora se recupera, fue también el primer artículo publicado en los Anales de la Casa de Salud Valdecilla.ABSTRACT: The Casa de Salud Valdecilla was officially inaugurated in October 1929. One of its vectors of development was research. The Medical Institute of Postgraduates, dedicated to research, was inaugurated in January 1930. The inauguration ceremony had a prominent figure: Dr. González-Aguilar, Chief Professor of the Clinic of Bones and Joints of the Casa de Salud Valdecilla. His inaugural conference, now recovered, was also the first article published in the Annals of the Casa de Salud Valdecilla

Effect of cutting height, a bacterial inoculant and a fibrolytic enzyme on corn (Zea mays L.) silage quality

This study aimed to evaluate cutting height (CH) effects on ensiled corn without additives (C), with a lactic acid bacteria inoculant (L), a fibrolytic enzyme (F), or a mixture of both (FL), considering chemical composition and both in vitro digestibility dry matter (IVDMD) and in vitro neutral detergent fiber (IVNDFD). Corn was harvested at three different cutting heights (12, 25 or 42 cm above the soil) and ensiled with or without additives (AD). Data was analyzed according to a factorial design, with a 3 x 4 arrangement of treatments and three repeats. Dry matter content was highest in C12 and lowest in F12 (P<0.05) silages. As cutting height was higher, cell wall content was lower (P<0.05). Even considering it increased after the use of additives (P<0.05), the highest values occurred with FL silages. Crude protein was equal (P˃0.05) between CH and increased (P<0.05) with AD. The highest IVDMD was observed for 42 cm CH, while IVDMD and IVNDFD were higher in C and F, but lower with FL. None of the inoculation treatments, alone or combined improved corn silage quality. In fact, FL combination decreased such quality. Highlights: The efficacy of lactic acid bacteria (LAB) and exogenous fibrolytic enzyme (EFE) is a funtion of the amount of cell walls and sugars present in the maize plant at harvest. Adding LAB and EFE to maize forage harvested at different cutting heights did not improve silage quality, in fact, the combination of both additives decreased silage quality. Further studies are needed to prove the efficacy of EFE and its combination with LAB on maize silage quality.This study aimed to evaluate cutting height (CH) effects on ensiled corn without additives (C), with a lactic acid bacteria inoculant (L), a fibrolytic enzyme (F), or a mixture of both (FL), considering chemical composition and both in vitro digestibility dry matter (IVDMD) and in vitro neutral detergent fiber (IVNDFD). Corn was harvested at three different cutting heights (12, 25 or 42 cm above the soil) and ensiled with or without additives (AD). Data was analyzed according to a factorial design, with a 3 x 4 arrangement of treatments and three repeats. Dry matter content was highest in C12 and lowest in F12 (P<0.05) silages. As cutting height was higher, cell wall content was lower (P<0.05). Even considering it increased after the use of additives (P<0.05), the highest values occurred with FL silages. Crude protein was equal (P˃0.05) between CH and increased (P<0.05) with AD. The highest IVDMD was observed for 42 cm CH, while IVDMD and IVNDFD were higher in C and F, but lower with FL. None of the inoculation treatments, alone or combined improved corn silage quality. In fact, FL combination decreased such quality. Highlights: The efficacy of lactic acid bacteria (LAB) and exogenous fibrolytic enzyme (EFE) is a funtion of the amount of cell walls and sugars present in the maize plant at harvest. Adding LAB and EFE to maize forage harvested at different cutting heights did not improve silage quality, in fact, the combination of both additives decreased silage quality. Further studies are needed to prove the efficacy of EFE and its combination with LAB on maize silage quality.

Ética Profesional y Responsabilidad Social Universitaria

este libro compila reflexiones y experiencias en responsabilidad social y ética profesional desde instituciones de Educación Superior. La responsabilidad social universitaria, como ámbito de investigación y de desarrollo conceptual y metodológico es transversal a las universidades, tanto desde el punto de vista organizacional, como desde el misional e investigativo. Quienes impulsen la responsabilidad social, requieren de ética profesional, que debe ser la clave para la construcción de principios que guíen a empresarios, políticos, gestores sociales, investigadores, entre otros, para lograr consensuar el a veces difícil equilibrio entre el bien común y el desarrollo personal

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

HE-LHC: The High-Energy Large Hadron Collider: Future Circular Collider Conceptual Design Report Volume 4

In response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre-of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries

FCC-ee: The Lepton Collider: Future Circular Collider Conceptual Design Report Volume 2

In response to the 2013 Update of the European Strategy for Particle Physics, the Future Circular Collider (FCC) study was launched, as an international collaboration hosted by CERN. This study covers a highest-luminosity high-energy lepton collider (FCC-ee) and an energy-frontier hadron collider (FCC-hh), which could, successively, be installed in the same 100 km tunnel. The scientific capabilities of the integrated FCC programme would serve the worldwide community throughout the 21st century. The FCC study also investigates an LHC energy upgrade, using FCC-hh technology. This document constitutes the second volume of the FCC Conceptual Design Report, devoted to the electron-positron collider FCC-ee. After summarizing the physics discovery opportunities, it presents the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan. FCC-ee can be built with today’s technology. Most of the FCC-ee infrastructure could be reused for FCC-hh. Combining concepts from past and present lepton colliders and adding a few novel elements, the FCC-ee design promises outstandingly high luminosity. This will make the FCC-ee a unique precision instrument to study the heaviest known particles (Z, W and H bosons and the top quark), offering great direct and indirect sensitivity to new physics