The origin of abundance gradients in the Milky Way: the predictions of different models

We aim at studying the abundance gradients along the Galactic disk and their dependence upon several parameters: a threshold in the surface gas density regulating star formation, the star formation efficiency, the timescale for the formation of the thin disk and the total surface mass density of the stellar halo. We test a model which considers a cosmological infall law. This law does not predict an inside-out disk formation, but it allows to well fit the properties of the solar vicinity. We study several cases. We find that to reproduce at the same time the abundance, star formation rate and surface gas density gradients along the Galactic disk it is necessary to assume an inside-out formation for the disk. The threshold in the gas density is not necessary and the same effect could be reached by assuming a variable star formation efficiency. A cosmologically derived infall law with an inside-out process for the disk formation and a variable star formation efficiency can indeed well reproduce all the properties of the disk. However, the cosmological model presented here does not have sufficient resolution to capture the requested inside-out formation for the disk.Comment: 13 pages, 17 figures and 2 tables. Accepted for publication in Astronomy & Astrophysic

Chemical gradients in the Milky Way from the RAVE data

Aims. We aim at measuring the chemical gradients of the elements Mg, Al, Si, and Fe along the Galactic radius to provide new constraints on the chemical evolution models of the Galaxy and Galaxy models such as the Besancon model. Thanks to the large number of stars of our RAVE sample we can study how the gradients vary as function of the distance from the Galactic plane. Methods. We analysed three different samples selected from three independent datasets: a sample of 19 962 dwarf stars selected from the RAVE database, a sample of 10 616 dwarf stars selected from the Geneva-Copenhagen Survey (GCS) dataset, and a mock sample (equivalent to the RAVE sample) created by using the GALAXIA code, which is based on the Besancon model. The three samples were analysed by using the very same method for comparison purposes. We integrated the Galactic orbits and obtained the guiding radii (R-g) and the maximum distances from the Galactic plane reached by the stars along their orbits (Z(max)). We measured the chemical gradients as functions of R-g at different Z(max). Results. We found that the chemical gradients of the RAVE and GCS samples are negative and show consistent trends, although they are not equal: at Z(max) < 0.4 kpc and 4.5 < R-g(kpc) < 9.5, the iron gradient for the RAVE sample is d[Fe/H]/dR(g) = -0.065 dex kpc(-1), whereas for the GCS sample it is d[Fe/H]/dR(g) = -0.043 dex kpc(-1) with internal errors of +/-0.002 and +/-0.004 dex kpc(-1), respectively. The gradients of the RAVE and GCS samples become flatter at larger Z(max). Conversely, the mock sample has a positive iron gradient of d[Fe/H]/dR(g) = +0.053 +/- 0.003 dex kpc(-1) at Z(max) < 0.4 kpc and remains positive at any Z(max). These positive and unrealistic values originate from the lack of correlation between metallicity and tangential velocity in the Besancon model. In addition, the low metallicity and asymmetric drift of the thick disc causes a shift of the stars towards lower R-g and metallicity which, together with the thin-disc stars with a higher metallicity and R-g, generates a fictitious positive gradient of the full sample. The flatter gradient at larger Z(max) found in the RAVE and the GCS samples may therefore be due to the superposition of thin-and thick-disc stars, which mimicks a flatter or positive gradient. This does not exclude the possibility that the thick disc has no chemical gradient. The discrepancies between the observational samples and the mock sample can be reduced by i) decreasing the density; ii) decreasing the vertical velocity; and iii) increasing the metallicity of the thick disc in the Besancon model

Open clusters towards the Galactic center: chemistry and dynamics. A VLT spectroscopic study of NGC6192, NGC6404, NGC6583

In the framework of the study of the Galactic metallicity gradient and its time evolution, we present new high-resolution spectroscopic observations obtained with FLAMES and the fiber link to UVES at VLT of three open clusters (OCs) located within $\sim$7~kpc from the Galactic Center (GC): NGC~6192, NGC~6404, NGC~6583. We also present new orbit determination for all OCs with Galactocentric distances (R$_{\rm{GC}}) \leq$8~kpc and metallicity from high-resolution spectroscopy. We aim to investigate the slope of the inner disk metallicity gradient as traced by OCs and at discussing its implication on the chemical evolution of our Galaxy. We have derived memberships of a group of evolved stars for each clusters, obtaining a sample of 4, 4, and 2 member stars in NGC~6192, NGC~6404, and NGC~6583, respectively. Using standard LTE analysis we derived stellar parameters and abundance ratios for the iron-peak elements Fe, Ni, Cr, and for the $\alpha$-elements Al, Mg, Si, Ti, Ca. We calculated the orbits of the OCs currently located within 8~kpc from the GC, and discuss their implication on the present-time radial location. {The average metallicities of the three clusters are all oversolar: [Fe/H]= $+0.12\pm0.04$ (NGC~6192), $+0.11\pm0.04$ (NGC 6404), $+0.37\pm0.03$ (NGC 6583). They are in qualitative agreement with their Galactocentric distances, being all internal OCs, and thus expected to be metal richer than the solar neighborhood. The abundance ratios of the other elements over iron [X/Fe] are consistent with solar values. The clusters we have analysed, together with other OC and Cepheid data, confirm a steep gradient in the inner disk, a signature of an evolutionary rate different than in the outer disk.Comment: 17 pages, 13 figures, A&A accepted for publicatio

A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

Increases in cellular Reactive Oxygen Species (ROS) concentration with age have been observed repeatedly in mammalian tissues. Concomitant increases in the proportion of replicatively senescent cells in ageing mammalian tissues have also been observed. Populations of mitotic human fibroblasts cultured in vitro, undergoing transition from proliferation competence to replicative senescence are useful models of ageing human tissues. Similar exponential increases in ROS with age have been observed in this model system. Tracking individual cells in dividing populations is difficult, and so the vast majority of observations have been cross-sectional, at the population level, rather than longitudinal observations of individual cells

The chemical evolution of a Milky Way-like galaxy: the importance of a cosmologically motivated infall law

We aim at finding a cosmologically motivated infall law to understand if the LambdaCDM cosmology can reproduce the main chemical characteristics of a Milky Way-like spiral galaxy. In this work we test several different gas infall laws, starting from that suggested in the two-infall model for the chemical evolution of the Milky Way by Chiappini et al., but focusing on laws derived from cosmological simulations which follows a concordance LambdaCDM cosmology. By means of a detailed chemical evolution model for the solar vicinity, we study the effects of the different gas infall laws on the abundance patterns and the G-dwarf metallicity distribution. The cosmological gas infall law predicts two main gas accretion episodes. By means of this cosmologically motivated infall law, we study the star formation rate, the SNIa and SNII rate, the total amount of gas and stars in the solar neighbourhood and the behaviour of several chemical abundances. We find that the results of the two-infall model are fully compatible with the evolution of the Milky Way with cosmological accretion laws. A gas assembly history derived from a DM halo, compatible with the formation of a late-type galaxy from the morphological point of view, can produce chemical properties in agreement with the available observations.Comment: This paper has 26 pages, 19 figures and 5 table

The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A

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