Direct electrocatalytic CO2 reduction in a pressurized tubular protonic membrane reactor

[EN] Power-to-methane technology enables storage of renewable elec-tricity in chemical energy, which can be transported and converted us-ing existing infrastructure. The moderate energy efficiency of this pro-cess is associated with high reactor exothermicity and complex thermal integration. Proton-ceramic electrochemical cells (PCECs) enable ther-mal combination of methanation and electrochemically driven H2 steps via endothermic reactions, boosting energy efficiency and heat man-agement. Here, we report single-step methane production from CO2 in a tubular PCEC at 450 degrees C and less than 30 bar. The H2 reactant is sup-plied by electrochemical pumping of protons from H2 in the external chamber. The electrochemical cell consists of an -25-mm-thick electro-lyte (BaZr0.8Ce0.1Y0.1O3-8) supported on a BaZr0.8Ce0.1Y0.1O3-8/Ni com-posite acting as a methanation catalyst. The reaction was studied as a function of total pressure, H2/CO2 ratio, and current density, reaching CH4 yields greater than 99% above 20 bar. High pressure and a CO2- rich atmosphere ameliorated the electrochemical behavior because of higher electrolyte hydration and boosted electrode kinetics.This study has received European Union Horizon 2020 Research and Innovation funding under grant agreement 838077 (eCOCO2 project) and financial support from the Spanish Government (PID2022-139663OB-I00, PRE2019-090959, and CEX2021-001230-S funded by MCIN/AEI/10.13039/501100011033) and MCIN with funding from NextGenerationEU (PRTR-C17.I1) within the Planes Complementarios con CCAA (Area of Green Hydrogen and Energy) and was carried out in the CSIC Interdisciplinary Thematic Platform (PTI+) Transicion Energetica Sostenible+ (PTI-TRANSENER+). Support from Camilla Vigen (CoorsTek Membrane Sciences) with manufacture of tubular cells is gratefully acknowledged.Quina-García, I.; Almar-Liante, L.; Catalán-Martínez, D.; Dayaghi, AM.; Martinez Feliu, A.; Norby, T.; Escolástico Rozalén, S.... (2023). Direct electrocatalytic CO2 reduction in a pressurized tubular protonic membrane reactor. Chem Catalysis (Online). 3(10):1-17. https://doi.org/10.1016/j.checat.2023.10076611731

Famílies botàniques de plantes medicinals

Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia, Assignatura: Botànica Farmacèutica, Curs: 2013-2014, Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són els recull de 175 treballs d’una família botànica d’interès medicinal realitzats de manera individual. Els treballs han estat realitzat per la totalitat dels estudiants dels grups M-2 i M-3 de l’assignatura Botànica Farmacèutica durant els mesos d’abril i maig del curs 2013-14. Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pel professor de l’assignatura i revisats i finalment co-avaluats entre els propis estudiants. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe

Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study

Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk

The Mid-Crustal Seismic Discontinuity In The Iberian Massif

19th International Symposium on Deep Seismic Profiling of the Continents and their Margins, 15th – 20 th March 2020, Perth, AustraliaA number of deep vertical incidence seismic experiments have been conducted in the Iberian Massif (SW Spain) since the 1990¿s, in order to unravel the architecture of the crust. The images obtained revealed an outstanding seismic signature change in the different sub-domains of the Iberian Massif and a conspicuous boundary separating the upper and lower crust. In this work we present the most complete and homogeneous image of all the vertical incidence seismic data acquired up to date, and use it to unravel the characteristics of this mid crustal feature, in order to shed light on the evolution of this portion of the Variscan Orogen. We use the depth and geometry of the mid-crustal boundary to estimate the amount of crustal thickening, later extension and partial melting underwent by the Gondwanan crust during the Variscan collision with the peri-Godwanan terranes and Laurussia. In the South Portuguese Zone (SW Iberia), the discontinuity divides the crust into two layers with similar thickness but featuring opposite vergence reflectivity, probably related to Variscan deformation. To the north, the mid-crustal discontinuity becomes shallower while the crustal thickness stays remains relatively constant in the Ossa Morena and Central Iberian zones. This could be an indication of that either the upper crust was originally thinner or that the whole crust thickened and was later isostatically re-equilibrated through erosion and uplift processes. The northwestern part of the Iberian Massif, in the Central Iberian and Galicia-Trás-os-Montes zones, show little remnants of the mid-crustal discontinuity or it is located very deep, resulting in a very thin lower crust. These areas were generally affected by the late Variscan crustal melting, while in the Central Iberian Zone, melting seems to be limited to the upper crust. The conspicuous mid-crustal feature divides an upper and a lower crust exhibiting contrasting reflectivity and geometry, and provide evidences of the different mechanisms to accommodate deformation, and may represent the Iberian equivalent to what in other areas worldwide are interpreted as Conrad Discontinuity.Funding resources: EU EIT-RawMaterials Ref: 17024_20170331_92304; MINECO: CGL2016-81964-REDE CGL2014-56548-P: JCYL: SA065P17

Geometry and Evolution of the Iberian Massif as Deduced from the Geometry of a Mid-Crustal Seismic Discontinuity

AGU General Meeting 2019, in San Francisco, 9-13 december 2019Normal incidence deep seismic reflection experiments conducted in the Iberian Massif since the 90's show an outstanding change in the seismic signature at upper and lower crustal levels and a conspicuous boundary separating both domains. This mid crustal feature gives us insights on the evolution of this part of the Variscan Orogen. Its depth and geometry can be related with the amount of crustal thickening, later extension and partial melting underwent by the Gondwanan crust during the Variscan collision with peri-Godwanan terranes and Laurussia. To the SW, in the South Portuguese Zone, this discontinuity divides the crust into two layers of similar thickness but featuring opposite vergence reflectivity, which probably represents Variscan deformation. As we move to the N, in the Ossa Morena and Central Iberian zones, the discontinuity becomes shallower, but crustal thickness stays relatively constant. This indicates that either the upper crust was originally thinner or that the whole crust thickened and was later re-equilibrated isostatically through erosion and uplift. To the NW of the Iberian Massif, the Central Iberian and Galicia-Trás-os-Montes zones, both affected by generalized late Variscan crustal melting, show little remnants of this feature or it is rather deep, leaving an extremely thin lower crust. Contrarily, in Central Spain, but still in the Central Iberian Zone, melting seems to have affected the upper crust but has left part of the lower crust unaffected. The geometry of this mid crustal boundary, as observed in the most complete and homogeneous seismic image of all the vertical incidence seismic data acquired in the Iberian Massif up to date and here presented, can help to understand its significance. This striking feature evidences contrasting deformation and different mechanisms to accommodate it at upper and lower crustal levels and may represent the Iberian equivalent of what, in other areas worldwide, has been named as Conrad Discontinuity

Mixed proton and electron conducting double perovskite anodes for stable and efficient tubular proton ceramic electrolysers

Hydrogen production from water electrolysis is a key enabling energy storage technology for the large-scale deployment of intermittent renewable energy sources. Proton ceramic electrolysers (PCEs) can produce dry pressurized hydrogen directly from steam, avoiding major parts of cost-driving downstream separation and compression. However, the development of PCEs has suffered from limited electrical efficiency due to electronic leakage and poor electrode kinetics. Here, we present the first fully operational BaZrO3-based tubular PCE, with 10 cm2 active area and a hydrogen production rate above 15 Nml min−1. The novel steam anode Ba1−xGd0.8La0.2+xCo2O6−δ exhibits mixed p-type electronic and protonic conduction and low activation energy for water splitting, enabling total polarization resistances below 1 Ω cm2 at 600 °C and Faradaic efficiencies close to 100% at high steam pressures. These tubular PCEs are mechanically robust, tolerate high pressures, allow improved process integration and offer scale-up modularity

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

The interaction between intercellular adhesion molecules (ICAM) and the integrin leukocyte function-associated antigen-1 (LFA-1) is crucial for the regulation of several physiological and pathophysiological processes like cell-mediated elimination of tumor or virus infected cells, cancer metastasis, or inflammatory and autoimmune processes. Using purified proteins it was reported a species restriction for the interaction of ICAM-1 and LFA-1, being mouse ICAM-1 able to interact with human LFA-1 but not human ICAM-1 with mouse LFA-1. However, in vivo results employing tumor cells transfected with human ICAM-1 suggest that functionally mouse LFA-1 can recognize human ICAM-1. In order to clarify the interspecies cross-reactivity of the ICAM-1/LFA-1 interaction, we have performed functional studies analyzing the ability of human soluble ICAM-1 and human/mouse LFA-1 derived peptides to inhibit cell aggregation and adhesion as well as cell-mediated cytotoxicity in both mouse and human systems. In parallel, the affinity of the interaction between mouse LFA-1-derived peptides and human ICAM-1 was determined by calorimetry assays. According to the results obtained, it seems that human ICAM-1 is able to interact with mouse LFA-1 on intact cells, which should be taking into account when using humanized mice and xenograft models for the study of immune-related processes

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

The interaction between intercellular adhesion molecules (ICAM) and the integrin leukocyte function-associated antigen-1 (LFA-1) is crucial for the regulation of several physiological and pathophysiological processes like cell-mediated elimination of tumor or virus infected cells, cancer metastasis, or inflammatory and autoimmune processes. Using purified proteins it was reported a species restriction for the interaction of ICAM-1 and LFA-1, being mouse ICAM-1 able to interact with human LFA-1 but not human ICAM-1 with mouse LFA-1. However, in vivo results employing tumor cells transfected with human ICAM-1 suggest that functionally mouse LFA-1 can recognize human ICAM-1. In order to clarify the interspecies cross-reactivity of the ICAM-1/LFA-1 interaction, we have performed functional studies analyzing the ability of human soluble ICAM-1 and human/mouse LFA-1 derived peptides to inhibit cell aggregation and adhesion as well as cell-mediated cytotoxicity in both mouse and human systems. In parallel, the affinity of the interaction between mouse LFA-1-derived peptides and human ICAM-1 was determined by calorimetry assays. According to the results obtained, it seems that human ICAM-1 is able to interact with mouse LFA-1 on intact cells, which should be taking into account when using humanized mice and xenograft models for the study of immune-related processes