1,019 research outputs found
Studies on growth rates in pigs and the effect of birth weight
End of project reportThe purpose of this study was to assess some environmental and management factors that affect growth performance on commercial pig units. In experiment 1, a survey was carried out on 22 pig units of known growth performance in south-west Ireland to compare management factors between those showing poor and good growth rates. Low growth rate appears to be due to the cumulative effect of a combination of factors. Experiment 2 was conducted to determine the effects of providing an
additional feeder on performance of weaned piglets. No benefits were
recorded. Feed consumed from the additional feeder was a replacement for
feed that otherwise would have been consumed from the control hopper
feeder.
Experiment 3 was designed to determine if pig performance and efficiency of
growth were affected by weight at birth and at weaning. Lightweight pigs
showed inferior growth performance up to the finisher period. Although they
compensated some of the inferior growth towards the time of slaughter, they
never reached the weights of the heavy birth-weight animals. Males were
either significantly heavier or tended to be heavier than females throughout.
There was no significant difference between the sexes in the number of days
to slaughter. Light and heavy pigs did not differ in the levels of IGF-1 in their
blood plasma; however lightweight pigs had significantly lower IgG preweaning.
Experiment 4 aimed to determine whether piglet birth weight influenced
growth performance, plasma IGF-1 concentrations and muscle fibre
characteristics at day 42 of life. At slaughter (Day 42) light birth weight pigs
were significantly (P < 0.001) lighter. Plasma IGF-1 concentration was lower
by 28% (P=0.06) in light pigs. Muscle fibre cross sectional area and total fibre
number were not significantly different between groups. This study should be
repeated with bigger numbers
The Design of 4××4 4 Multimode Interference Coupler Based Microring Resonators on an SOI Platform, Journal of Telecommunications and Information Technology, 2009, nr 2
This paper would like to propose a novel microring resonator based on 4 ×4 multimode interference (MMI) couplers. The device acts as two separate microring resonators just in one structure. The transfer matrix method and the three dimensional beam propagation method (3D-BPM) are used to verify the working principle of the device. The device is then designed on silicon on insulator (SOI) technology. This device may be a very promising building block for optical switches, filters, add-drop multiplexers, delay lines and modulators
Heavy--light mesons in a bilocal effective theory
Heavy--light mesons are described in an effective quark theory with a
two--body vector--type interaction. The bilocal interaction is taken to be
instantaneous in the rest frame of the bound state, but formulated covariantly
through the use of a boost vector. The chiral symmetry of the light flavor is
broken spontaneously at mean field level. The framework for our discussion of
bound states is the effective bilocal meson action obtained by bosonization of
the quark theory. Mesons are described by 3--dimensional wave functions
satisfying Salpeter equations, which exhibit both Goldstone solutions in the
chiral limit and heavy--quark symmetry for . We present
numerical solutions for pseudoscalar -- and --mesons. Heavy--light meson
spectra and decay constants are seen to be sensitive to the description of
chiral symmetry breaking (dynamically generated vs.\ constant quark mass).Comment: (34 p., standard LaTeX, 7 PostScript figures appended)
UNITUE-THEP-17/9
Dyson-Schwinger Equations: Density, Temperature and Continuum Strong QCD
Continuum strong QCD is the application of models and continuum quantum field
theory to the study of phenomena in hadronic physics, which includes; e.g., the
spectrum of QCD bound states and their interactions; and the transition to, and
properties of, a quark gluon plasma. We provide a contemporary perspective,
couched primarily in terms of the Dyson-Schwinger equations but also making
comparisons with other approaches and models. Our discourse provides a
practitioners' guide to features of the Dyson-Schwinger equations [such as
confinement and dynamical chiral symmetry breaking] and canvasses
phenomenological applications to light meson and baryon properties in cold,
sparse QCD. These provide the foundation for an extension to hot, dense QCD,
which is probed via the introduction of the intensive thermodynamic variables:
chemical potential and temperature. We describe order parameters whose
evolution signals deconfinement and chiral symmetry restoration, and chronicle
their use in demarcating the quark gluon plasma phase boundary and
characterising the plasma's properties. Hadron traits change in an equilibrated
plasma. We exemplify this and discuss putative signals of the effects. Finally,
since plasma formation is not an equilibrium process, we discuss recent
developments in kinetic theory and its application to describing the evolution
from a relativistic heavy ion collision to an equilibrated quark gluon plasma.Comment: 103 Pages, LaTeX, epsfig. To appear in Progress in Particle and
Nuclear Physics, Vol. 4
Treatment Motivation Differences between Minnesota and Methadone Program Patients with Substance Use Disorder in Latvia
publishersversionPeer reviewe
Asymmetric recurrent laryngeal nerve conduction velocities and dorsal cricoarytenoid muscle electromyographic characteristics in clinically normal horses
The dorsal cricoarytenoid (DCA) muscles, are a fundamental component of the athletic horse’s respiratory system: as the sole abductors of the airways, they maintain the size of the rima glottis which is essential for enabling maximal air intake during intense exercise. Dysfunction of the DCA muscle leads to arytenoid collapse during exercise, resulting in poor performance. An electrodiagnostic study including electromyography of the dorsal cricoarytenoid muscles and conduction velocity testing of the innervating recurrent laryngeal nerves (RLn) was conducted in horses with normal laryngeal function. We detected reduced nerve conduction velocity of the left RLn, compared to the right, and pathologic spontaneous activity (PSA) of myoelectrical activity within the left DCA muscle in half of this horse population and the horses with the slowest nerve conduction velocities. The findings in this group of horses are consistent with left sided demyelination and axonal loss, consistent with Recurrent Laryngeal Neuropathy (RLN), a highly prevalent degenerative disorder of the RLn in horses that predominantly affects the left side. The detection of electromyographic changes compatible with RLN in clinically unaffected horses is consistent with previous studies that identified “subclinical” subjects, presenting normal laryngeal function despite neuropathologic changes within nerve and muscle confirmed histologically
Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma
SummaryTumor heterogeneity has been implicated in tumor growth and progression as well as resistance to therapy. We present an example of genetic heterogeneity in human malignant brain tumors in which multiple closely related driver genes are amplified and activated simultaneously in adjacent intermingled cells. We have observed up to three different receptor tyrosine kinases (EGFR, MET, PDGFRA) amplified in single tumors in different cells in a mutually exclusive fashion. Each subpopulation was actively dividing, and the genetic changes resulted in protein production, and coexisting subpopulations shared common early genetic mutations indicating their derivation from a single precursor cell. The stable coexistence of different clones within the same tumor will have important clinical implications for tumor resistance to targeted therapies
A new Perspective on the Scalar meson Puzzle, from Spontaneous Chiral Symmetry Breaking Beyond BCS
We introduce coupled channels of Bethe-Salpeter mesons both in the boundstate
equation for mesons and in the mass gap equation for chiral symmetry.
Consistency is insured by the Ward Identities for axial currents, which
preserve the Goldstone boson nature of the pion and prevents a systematic shift
of the hadron spectrum. We study the decay of a scalar meson coupled to a pair
of pseudoscalars. We also show that coupled channels reduce the breaking of
chiral symmetry, with the same Feynman diagrams that appear in the coupling of
a scalar meson to a pair of pseudoscalar mesons. Exact calculations are
performed in a particular confining quark model, where we find that the
groundstate meson is the f_0(980) with a partial decay
width of 40MeV. We also find a 30% reduction of the chiral condensate due to
coupled channels.Comment: 17 pages, Revtex, 8 eps figures, and several eps diagrams in
equation
Regular breakfast consumption and type 2 diabetes risk markers in 9- to 10-year-old children in the child heart and health study in England (CHASE): a cross-sectional analysis.
BACKGROUND: Regular breakfast consumption may protect against type 2 diabetes risk in adults but little is known about its influence on type 2 diabetes risk markers in children. We investigated the associations between breakfast consumption (frequency and content) and risk markers for type 2 diabetes (particularly insulin resistance and glycaemia) and cardiovascular disease in children.
METHODS AND FINDINGS: We conducted a cross-sectional study of 4,116 UK primary school children aged 9-10 years. Participants provided information on breakfast frequency, had measurements of body composition, and gave fasting blood samples for measurements of blood lipids, insulin, glucose, and glycated haemoglobin (HbA1c). A subgroup of 2,004 children also completed a 24-hour dietary recall. Among 4,116 children studied, 3,056 (74%) ate breakfast daily, 450 (11%) most days, 372 (9%) some days, and 238 (6%) not usually. Graded associations between breakfast frequency and risk markers were observed; children who reported not usually having breakfast had higher fasting insulin (percent difference 26.4%, 95% CI 16.6%-37.0%), insulin resistance (percent difference 26.7%, 95% CI 17.0%-37.2%), HbA1c (percent difference 1.2%, 95% CI 0.4%-2.0%), glucose (percent difference 1.0%, 95% CI 0.0%-2.0%), and urate (percent difference 6%, 95% CI 3%-10%) than those who reported having breakfast daily; these differences were little affected by adjustment for adiposity, socioeconomic status, and physical activity levels. When the higher levels of triglyceride, systolic blood pressure, and C-reactive protein for those who usually did not eat breakfast relative to those who ate breakfast daily were adjusted for adiposity, the differences were no longer significant. Children eating a high fibre cereal breakfast had lower insulin resistance than those eating other breakfast types (p for heterogeneity <0.01). Differences in nutrient intakes between breakfast frequency groups did not account for the differences in type 2 diabetes markers.
CONCLUSIONS: Children who ate breakfast daily, particularly a high fibre cereal breakfast, had a more favourable type 2 diabetes risk profile. Trials are needed to quantify the protective effect of breakfast on emerging type 2 diabetes risk. Please see later in the article for the Editors' Summary
Haptoglobin Phenotype, Preeclampsia Risk and the Efficacy of Vitamin C and E Supplementation to Prevent Preeclampsia in a Racially Diverse Population
Haptoglobin's (Hp) antioxidant and pro-angiogenic properties differ between the 1-1, 2-1, and 2-2 phenotypes. Hp phenotype affects cardiovascular disease risk and treatment response to antioxidant vitamins in some non-pregnant populations. We previously demonstrated that preeclampsia risk was doubled in white Hp 2-1 women, compared to Hp 1-1 women. Our objectives were to determine whether we could reproduce this finding in a larger cohort, and to determine whether Hp phenotype influences lack of efficacy of antioxidant vitamins in preventing preeclampsia and serious complications of pregnancy-associated hypertension (PAH). This is a secondary analysis of a randomized controlled trial in which 10,154 low-risk women received daily vitamin C and E, or placebo, from 9-16 weeks gestation until delivery. Hp phenotype was determined in the study prediction cohort (n = 2,393) and a case-control cohort (703 cases, 1,406 controls). The primary outcome was severe PAH, or mild or severe PAH with elevated liver enzymes, elevated serum creatinine, thrombocytopenia, eclampsia, fetal growth restriction, medically indicated preterm birth or perinatal death. Preeclampsia was a secondary outcome. Odds ratios were estimated by logistic regression. Sampling weights were used to reduce bias from an overrepresentation of women with preeclampsia or the primary outcome. There was no relationship between Hp phenotype and the primary outcome or preeclampsia in Hispanic, white/other or black women. Vitamin supplementation did not reduce the risk of the primary outcome or preeclampsia in women of any phenotype. Supplementation increased preeclampsia risk (odds ratio 3.30; 95% confidence interval 1.61-6.82, p<0.01) in Hispanic Hp 2-2 women. Hp phenotype does not influence preeclampsia risk, or identify a subset of women who may benefit from vitamin C and E supplementation to prevent preeclampsia
- …