First Confirmed Detection of a Bipolar Molecular Outflow from a Young Brown Dwarf

Studying the earliest stages in the birth of stars is crucial for understanding how they form. Brown dwarfs with masses between that of stars and planets are not massive enough to maintain stable hydrogen-burning fusion reactions during most of their lifetime. Their origins are subject to much debate in recent literature because their masses are far below the typical mass where core collapse is expected to occur. We present the first confirmed evidence that brown dwarfs undergo a phase of molecular outflow that is typical of young stars. Using the Submillimeter Array, we have obtained a map of a bipolar molecular outflow from a young brown dwarf. We estimate an outflow mass of 1.6 x 10^-4 M_Sun and a mass-loss rate of 1.4 x 10^-9 M_Sun. These values are over two orders of magnitude smaller than the typical ones for T Tauri stars. From our millimiter continuum data and our own analysis of Spitzer infrared photometry, we estimate that the brown dwarf has a disk with a mass of 8 x 10^-3 M_Sun and an outer disk radius of 80 AU. Our results demonstrate that the bipolar molecular outflow operates down to planetary masses, occurring in brown dwarfs as a scaled-down version of the universal process seen in young stars.Comment: accepted by ApJ Letter

Herschel Observations of Disks around Late-type Stars

A set of twenty late-type (K5-M5) stars were observed with the Herschel Space Observatory at 100 and 160 microns with the goal of searching for far-infrared excesses indicative of the presence of circumstellar disks. Out of this sample, four stars (TYC 7443-1102-1, TYC 9340-437-1, GJ 784 and GJ 707) have infrared excesses above their stellar photospheres at either 100 or 160 μm or both. At 100 microns TYC 9340-437-1 is spatially resolved with a shape that suggests it is surrounded by a face-on disk. The 100 μm excess flux associated with GJ 707 is marginal at around 3σ. The excess flux associated with GJ 784 is most likely due to a background galaxy as the dust radius estimated from the spectral energy fit implies that any associated dust disk should have been resolved in the Herschel images but is not. TYC 7443-1102-1 has been observed with ALMA which resolves the emission at its location into two distinct sources making the Herschel excess most likely also due to a background galaxy. It is worth noting that this star is in the 23 Myr old β Pic association. With a disk luminosity on the order of 10⁻³ L_*, this system is an ideal follow-up target for high-contrast imaging and ALMA

Elusive Majority of Young Moving Groups. I. Young Binaries and Lithium-rich Stars in the Solar Neighborhood

Young stars in the solar neighborhood serve as nearby probes of stellar evolution and represent promising targets to directly image self-luminous giant planets. We have carried out an all-sky search for late-type (≈K7–M5) stars within 100 pc selected primarily on the basis of activity indicators from the Galaxy Evolution Explorer and ROSAT. Approximately 2000 active and potentially young stars are identified, of which we have followed up over 600 with low-resolution optical spectroscopy and over 1000 with diffraction-limited imaging using Robo-AO at the Palomar 1.5 m telescope. Strong lithium is present in 58 stars, implying ages spanning ≈10–200 Myr. Most of these lithium-rich stars are new or previously known members of young moving groups including TWA, β Pic, Tuc-Hor, Carina, Columba, Argus, AB Dor, Upper Centaurus Lupus, and Lower Centaurus Crux; the rest appear to be young low-mass stars without connections to established kinematic groups. Over 200 close binaries are identified down to 0.”2—the vast majority of which are new—and will be valuable for dynamical mass measurements of young stars with continued orbit monitoring in the future

Elusive Majority of Young Moving Groups. I. Young Binaries and Lithium-rich Stars in the Solar Neighborhood

Young stars in the solar neighborhood serve as nearby probes of stellar evolution and represent promising targets to directly image self-luminous giant planets. We have carried out an all-sky search for late-type (≈K7–M5) stars within 100 pc selected primarily on the basis of activity indicators from the Galaxy Evolution Explorer and ROSAT. Approximately 2000 active and potentially young stars are identified, of which we have followed up over 600 with low-resolution optical spectroscopy and over 1000 with diffraction-limited imaging using Robo-AO at the Palomar 1.5 m telescope. Strong lithium is present in 58 stars, implying ages spanning ≈10–200 Myr. Most of these lithium-rich stars are new or previously known members of young moving groups including TWA, β Pic, Tuc-Hor, Carina, Columba, Argus, AB Dor, Upper Centaurus Lupus, and Lower Centaurus Crux; the rest appear to be young low-mass stars without connections to established kinematic groups. Over 200 close binaries are identified down to 0.”2—the vast majority of which are new—and will be valuable for dynamical mass measurements of young stars with continued orbit monitoring in the future

Herschel observations of disks around late-type stars

A set of twenty late-type (K5-M5) stars were observed with the Herschel Space Observatory at 100 and 160 microns with the goal of searching for far-infrared excesses indicative of the presence of circumstellar disks. Out of this sample, four stars (TYC 7443-1102-1, TYC 9340-437-1, GJ 784 and GJ 707) have infrared excesses above their stellar photospheres at either 100 or 160 μm or both. At 100 microns TYC 9340-437-1 is spatially resolved with a shape that suggests it is surrounded by a face-on disk. The 100 μm excess flux associated with GJ 707 is marginal at around 3σ. The excess flux associated with GJ 784 is most likely due to a background galaxy as the dust radius estimated from the spectral energy fit implies that any associated dust disk should have been resolved in the Herschel images but is not. TYC 7443-1102-1 has been observed with ALMA which resolves the emission at its location into two distinct sources making the Herschel excess most likely also due to a background galaxy. It is worth noting that this star is in the 23 Myr old β Pic association. With a disk luminosity on the order of 10-3 L*, this system is an ideal follow-up target for high-contrast imaging and ALMA

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Characterizing the disk around the TW Hydrae Association brown dwarf 2MASSW J1207334-393254

We present detailed modeling of the disk around the TW Hydrae Association (TWA) brown dwarf 2MASSW J1207334 - 393254 (2M1207), using Spitzer observations from 3.6 to 24 mu m. The spectral energy distribution (SED) does not show a high amount of flaring. We have obtained a good fit using a flat disk of mass between 10(-4) and 10(-6) M-circle dot, M less than or similar to 10(-11) M-circle dot yr(-1), and a large inclination angle between 60 degrees and 70 degrees. We have used three different grain models to fit the 10 mu m Si emission feature, and have found the results to be consistent with ISM-like dust. In comparison with other TWA members, this suggests lesser dust processing for 2M1207, which could be explained by mechanisms such as aggregate fragmentation and/or turbulent mixing. We have found a good fit using an inner disk radius equal to the dust sublimation radius, which indicates the absence of an inner hole in the disk. This suggests the presence of a small K - L' excess, similar to the observed K - [3.6] excess.Peer reviewe

Infrared Observations of a Mid-L Dwarf with Strong Hα Emission

We present Spitzer/IRAC observations of the L5 dwarf, 2MASSI J1315309-264951 (2M 1315). This ultracool dwarf is known to display strong emission in the H alpha line. The spectral energy distribution (SED) for this object does not show any IR excess that would indicate the presence of an accretion disk. Although the IRAC colors for 2M 1315 are consistent with other L dwarfs, they seem to be redder by similar to 0.1 mag than the other L5 dwarfs, and more like the late-type L dwarfs. The existing six epochs of spectroscopy suggest that the emission in H alpha is not persistent, but shows long-term variability between a flare value of similar to 100 angstrom and a quiescent value of similar to 25 angstrom. Chromospheric activity seems to be the most likely cause, which is also indicated by the detection of Na I D lines in emission (Fuhrmeister et al.). We have measured a proper motion of 0.79 '' +/- 0.06 '' yr(-1), which corresponds to a tangential velocity of similar to 81 km s(-1) at a distance of similar to 22 pc. The high V-tan for this object suggests an old age. Evolutionary models indicate lower limits of 3.3 Gyr (Chabrier et al.) or 1.4 Gyr (Burrows et al.) for this magnetically active L dwarf to be a stable hydrogen burning star. There seem to be no observational differences between this old L dwarf that has H alpha emission and the other field L dwarfs withoutPeer reviewe