48 research outputs found
Preparing for generation Z:how can technology enhanced learning be firmly embedded in our students' learning experience? A case study from Abertay University
Abertay is a relatively small, modern university (undergraduate population of around 4000) with a wide portfolio and a diverse student population. Around 35% of our students are direct entry from local partner colleges to years 2 and 3 of our programmes and a significant number are first generation higher education within their families. As such, partnership working with colleges and support to aid student transitions are key aspects of Abertay’s provision. Since 2013/14, the university has developed and implemented a new Teaching and Learning Enhancement strategy that has catalysed wholescale transformation across the institution. This paper provides an overview of technology enhanced learning at the university with the drivers for change being to the quality of our students' learning experience, improve student retention and progression and enhance learners’ engagement
Land use change in a Mediterranean metropolitan region and its periphery: Assessment of conservation policies through CORINE land cover data and Markov models
Sustainable territorial management requires reliable assessment of the impact of conservation policies on landscape structure and dynamics. Euro-Mediterranean regions present a remarkable biodiversity which is linked in part to traditional land use practices and which is currently threatened by global change. The effectiveness of one-decade conservation policies against land use changes was examined in Central Spain (Madrid Autonomous Community). A Markov model of landscape dynamics was parameterized with CORINE Land Cover information and transition matrices were obtained. The methods were applied in both protected and unprotected areas to examine whether the intensity and direction of key land use changes —urbanisation, agricultural intensification and land abandonment— differed significantly depending on the protection status of those areas. Protected areas experienced slower rates of agricultural intensification processes and faster rates of land abandonment, with respect to those which occurred in unprotected areas. It illustrates how simple mathematical tools and models —parameterized with available data— can provide to managers and policy makers useful indicators for conservation policy assessment and identification of land use transitions
Caracterización hidrogeoquímica de efluentes de escombreras en el grupo minero la Zarza-Perruna
info:eu-repo/semantics/publishedVersio
Proyecto MINENERGYDESIGN: modelo de aplicación de la metodología Design Thinking en el aprendizaje en la gestión de proyectos de ingeniería
La gestión de proyectos en ingeniería se está transformando hacia un proceso dinámico y ágil, donde la interacción e iteración continua con el cliente/usuario es una realidad. Para el éxito del proyecto, y la resolución del problema de ingeniería, se deben considerar nuevas herramientas de aprendizaje, donde el alumno debe trabajar entre otras competencias, la creatividad (aplicada a la resolución de problemas), el trabajo en equipo, la comunicación y el liderazgo. El objetivo de este trabajo es mostrar cómo la metodología Design Thinking incrementa el aprendizaje en el área de gestión de proyectos proponiendo una sencilla iteración en tres etapas hasta alcanzar un prototipo funcional. De esta forma, el alumnado adquiere de una forma práctica las competencias demandadas por el entorno profesional, permitiendo tener una primera aproximación y experiencia en aula sobre la gestión de proyectos
VR-STEREO: La enseñanza de la Proyección Estereográfica en asignaturas de Expresión Gráfica y Mecánica de Rocas a través de la Realidad Virtual y el Laboratorio de Impresión 3D
La investigación resumida en este trabajo se orienta hacia la mejora en el proceso de aprendizaje de los estudiantes de ingeniería en el bloque dedicado a la Proyección Estereográfica. Es un sistema de representación ampliamente utilizado en los proyectos de ingeniería (estabilidad de taludes, estudio de discontinuidades, Geología Estructural), que, al no estar incluido en el curriculum de ninguna asignatura de cursos previos al ciclo universitario, dificulta la comprensión de sus conceptos teóricos. Por ello, se ha desarrollado un plan de inmersión en este sistema, que incluye el desarrollo de un software para resolver problemas de Estereográfica y la grabación de videos (aula invertida) en canteras y taludes sobre la toma de los datos in situ que serán utilizados posteriormente. La aplicación de animaciones (Blender®), la utilización de Realidad Virtual (RV) y el modelado con impresión 3D completan las estrategias incluidas para mejorar el grado de comprensión de los alumnos
Implantación de un sistema de vídeo-tutoría basado en dudas frecuentes: vFAQ
La tutoría, es un recurso didáctico imprescindible en el proceso de aprendizaje. Con ella, el alumnado recibe una atención específica sobre dudas y problemas de comprensión concretos. Sin embargo, la atención personalizada de la duda ocurrida durante el proceso de aprendizaje autónomo fuera de aula se produce con un retraso cuando la tutoría se da de forma presencial. En este proyecto, se presentan los resultados preliminares de la implantación de las vFAQ en titulaciones de Graduado en Ingeniería. Estas consisten en la recopilación sistemática de vídeos que responden a dudas frecuentes, errores más comunes en ejercicios y pruebas de evaluación y descripciones metodológicas. Los resultados obtenidos muestran una relación directa entre el empleo de este recurso didáctico y la calificación final obtenida, sugiriendo que los vFAQ pueden ser una herramienta que mejore la participación del alumnado en las actividades de las asignaturas
Konsumsi Minyak Goreng dan Vitamin A pada Beberapa Kelompok Umur di Dua Kabupaten
Indonesia plans to implement mandatory vitamin A fortification of cooking oil. A pilot study of voluntary vitamin A fortification in unbranded cooking oil showed that vitamin A status improved significantly a year afterfortification for five age groups except for children 12-23 months of age. The objective of the study was to measure cooking oil consumption and dietary consumption of vitamin A in children, women of reproductive age(WRA), and lactating mothers. The study was a cross-sectional study in Tasikmalaya and Ciamis, Indonesia, covering 1.594 samples randomly selected of poor households. Cooking oil was collected at household byrecall of usual cooking oil purchase and individual sample by 2x24h recall of food consumption. The results showed that households prefer bought unbranded cooking oil sold in plastic pouch at foodstall (warung) nearbyhome (96.2%), purchased oil every 1-3 days (60.6%), each purchace contained < 250 mL oil (73.9%). The average (mean+SE) cooking oil consumption at household was 27.5+1.0 mL/capita/day. Cooking oilconsumption at individual level on the average was 22.3+0.5 mL/capita/day lower compared to household consumption of oil, varied significantly of 2.4+0.4, 13.3+0.8, 23.0+1.0, 30.5+1.3, 33.5+1.2, 33.1+1.3 mL/day in 6-11, 12-23, 24-59 month old, 6-9 year old, WRA, and lactating mothers respectively. Cooking oil consumptionwas lower in children 6-11 and 12-23 months old which contributed to non-significant improvement of serum vitamin A level particularly in children 12-23 months old but not other groups since they consumed higher intake of cooking oil or still brestfed for children 6-11 month old
Vídeo-tutoriales y su influencia en el aprendizaje
En la última década se han desarrollado multitud de metodologías de enseñanza alternativas englobadas en el marco de la innovación educativa, con el objeto de fomentar la motivación de los alumnos, adaptarse a las nuevas tecnologías y mejorar el aprendizaje. En concreto, este estudio se centra en el uso de vídeo-tutoriales en los que se explica parte de la materia de la asignatura, de modo que los estudiantes pueden hacer uso de los vídeos como material de apoyo en un marco metodológico de “aula invertida”. Para evaluar el impacto de los vídeo-tutoriales, los alumnos se sometieron a dos pruebas de cuyos resultados se desprende la utilidad del método en la mejora de la adquisición de los resultados de aprendizaje. Además, se ha realizado una comparativa entre los resultados obtenidos en años anteriores con metodologías tradicionales y en este año con la nueva técnica para obtener una visión global de los resultados de su implementación y cuantificar la mejora en los resultados obtenidos por los alumnos
Impact of COVID-19 Lockdown in Eating Disorders: A Multicentre Collaborative International Study
Background. The COVID-19 lockdown has had a significant impact on mental health. Patients with eating disorders (ED) have been particularly vulnerable. Aims. (1) To explore changes in eating-related symptoms and general psychopathology during lockdown in patients with an ED from various European and Asian countries; and (2) to assess differences related to diagnostic ED subtypes, age, and geography. Methods. The sample comprised 829 participants, diagnosed with an ED according to DSM-5 criteria from specialized ED units in Europe and Asia. Participants were assessed using the COVID-19 Isolation Scale (CIES). Results. Patients with binge eating disorder (BED) experienced the highest impact on weight and ED symptoms in comparison with other ED subtypes during lockdown, whereas individuals with other specified feeding and eating disorders (OFSED) had greater deterioration in general psychological functioning than subjects with other ED subtypes. Finally, Asian and younger individuals appeared to be more resilient. Conclusions. The psychopathological changes in ED patients during the COVID-19 lockdown varied by cultural context and individual variation in age and ED diagnosis. Clinical services may need to target preventive measures and adapt therapeutic approaches for the most vulnerable patients
SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
© 2024 The Author(s). This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that regulates the function of the RNA-binding protein Hu antigen R (HuR), a hub in liver cancer. Here, we show that HuR is SUMOylated in the tumor sections of patients with hepatocellular carcinoma in contrast to the surrounding tissue, as well as in human cell line and mouse models of the disease. SUMOylation of HuR promotes major cancer hallmarks, namely proliferation and invasion, whereas the absence of HuR SUMOylation results in a senescent phenotype with dysfunctional mitochondria and endoplasmic reticulum. Mechanistically, SUMOylation induces a structural rearrangement of the RNA recognition motifs that modulates HuR binding affinity to its target RNAs, further modifying the transcriptomic profile toward hepatic tumor progression. Overall, SUMOylation constitutes a mechanism of HuR regulation that could be potentially exploited as a therapeutic strategy for liver cancer.This work was supported by grants to M.L.M.-C. from Departamento de Industria del Gobierno Vasco, Spain; Ministerio de Ciencia e Innovación, Spain (grant no. PID2020-117116RB-I00); European Regional Development Fund (ERDF), EU; and CIBERehd, which is funded by Instituto de Salud Carlos III (ISCIII), Spain. M.L.M.-C. and J.S. received funding from Ministerio de Ciencia e Innovación (grant no. RTC2019-007125-1) and ISCIII (grant no. DTS20/00138). M.L.M.-C. and R.M.L. acknowledge Ministerio de Ciencia e Innovación (grant no. RED2022-134397-T). M.L.M.-C. and J.M.B. were awarded with a grant from Fundación la Caixa, Spain (grant no. HR17-00601). M.L.M.-C., J.M.B., M.A.A., and J.J.G.M. acknowledge financial support from Fundación Científica de la Asociación Española Contra el Cáncer (AECC), Spain. M.S.R. recognizes funding from Fondo Sectorial de Investigación SRE - CONACYT, Mexico (grant no. 0280365); Horizon 2020 Research and Innovation Program funded under Marie Skłodowska-Curie Actions, EU (grant no. 765445); and REPÈRE and Programme de Prématuration from Région Occitanie, France. M.G., S.D., and K.M.-M. were supported by the National Institute on Aging (NIA), National Institutes of Health (NIH), US (grant no. Z01-AG000511-23). I.D.-M. is grateful for the grants received from Junta de Andalucía, Spain (grant no. BIO-198, US-1254317, P18-FR-3487, and P18-HO-4091); Ministerio de Ciencia, Innovación y Universidades, Spain (grant no. PGC2018-096049-BI00); and Fundación Ramón Areces, Spain. T.D. acknowledges Fondation ARC, France (grant no. 208084). J.J.G.M. was supported by Junta de Castilla y León, Spain (grant no. SA063P17); Fundación La Marató TV3, Spain (grant no. 201916-31); ISCIII (grant no. PI19/00819); CIBERehd; and ERDF (grant no. OLD-HEPAMARKER). M.A.A. recognizes Gobierno de Navarra, Spain (grant no. GºNa 42/21); Eurorregión Nueva Aquitania-Euskadi-Navarra, Spain; Ministerio de Ciencia e Innovación (grant no. PID2019-104878RB-I00); and CIBERehd. A.P. expresses gratitude to the European Research Council (ERC), EU (grant no. 804236) for their support. M.D.G. received financial support from Junta de Andalucía (grant no. PEMP-0036-2020 and BIO-0139); Ministerio de Universidades, Spain (grant no. FPU20/03957); ISCIII (grant no. PI20/01301), Fundación Sociedad Española de Endocrinología y Nutrición (FSEEN), Spain; CIBERehd; and CIBERobn, which is also funded by ISCIII. J.M.B. acknowledges Euskadi RIS3 (grant no. 2019222054, 2020333010, and 2021333003) and Elkartek programs from Gobierno Vasco (grant no. KK-2020/00008); ISCIII (grant no. PI18/01075, CPII19/00008, and PI21/00922); CIBERehd; PSC Support, UK; AMMF The Cholangiocarcinoma Charity, UK (grant no. EU/2019/AMMFt/001); Horizon 2020 Research and Innovation Program (grant no. 825510); ERDF; and PSC Partners Seeking a Cure, US. A.L. received financial support from the Damon Runyon-Rachleff Innovation Award, US (grant no. DR52-18) and the MERIT Award (R37) from the National Cancer Institute (NCI), NIH (grant no. R37CA230636). F.E. expresses his gratitude to ProteoRed from ISCIII (grant no. PT13/0001/0027) and CIBERehd. N.G.A.A. was funded by Ministerio de Ciencia, Innovación y Universidades (grant no. RTI2018-095700-B-I00). R.B. acknowledges financial support from Gobierno Vasco (grant no. IT1165-19); Ministerio de Economía, Industria y Competitividad, Spain (grant no. SAF2017-90900-REDT); Ministerio de Economía, Industria y Competitividad, ERDF (grant no. BFU2017-84653-P); Ministerio de Ciencia e Innovación (grant no. PID2020-114178GB-I00); and Horizon 2020 funded under Marie Skłodowska-Curie Actions (grant no. 765445-EU). A.M.A. acknowledges CIBERehd. L.A.M.-C. obtained grants from Ministerio de Economía y Competitividad (grant no. CSD2008-00005); Ministerio de Economía, Industria y Competitividad (grant no. BFU2016-77408-R); ISCIII; and EJP RD, EU (grant no. EJPRD19-040). I.G.-R. was supported by Ministerio de Economía, Industria y Competitividad (grant no. BES-2017-080435 ). M.S.-M. is grateful to the AECC, Sede de Bizkaia, Spain for the financial support. J.D.Z. was awarded with a grant from Ministerio de Economía, Industria y Competitividad (grant no. SEV-2016-0644-18-2). C.M. acknowledges Gobierno Vasco (grant no. IT-1264-19) and Ministerio de Ciencia e Innovación (grant no. PID2022-136788OB-I00). A.V.-C. was supported by Ministerio de Educación, Cultura y Deporte, Spain (grant no. FPU016/01513). C.F.-R. thanks Tekniker, Spain and CIC bioGUNE, Spain for financial support. A.G.-d.R. was funded by Bikaintek program from Gobierno Vasco (grant no. 48-AF-W1-2019-00012). N.G.-U. obtained a grant from Gobierno Vasco. T.C.D. expresses gratitude to AECC. J.S. received financial support from CIBERehd. C.M.R.-G. was supported by Ayudas a la Recualificación Margarita Salas from Universidad de Extremadura, Ministerio de Universidades financed by NextGenerationEU.Peer reviewe