Resistencia a la compresión del concreto F C =210 KG/cm" elaborado con cemento antisalitre MS y aditivo retardante de fragua plastiment TM - 12

En el presente informe de tesis se tiene como objetivos poder determinar el efecto de los aditivos retardantes plastificantes TM-12 en su resistencia frente a la comprensión del concreto mostrado en diferentes muestras de edades del concreto f´c = 210kg/cm2. Para ello, se tuvo una investigación descriptiva, correlacional y cuantitativa. Se consideraron 02 tipos de concreto: Concreto Patrón y Concreto experimental, para el último se tomó en cuenta dos dosificaciones con el mínimo y el máximo porcentaje de aditivo. Además, el número de muestras será de 4, para cada tipo de concreto (concentración), a las edades de 7 días, 14 días y 28 días, haciendo un total de 40 probetas. Con todo ello, se tuvo que: la Resistencia a la compresión de concreto óptimo y máximo que se puede obtener (457.9253), para valores óptimos y altos de cada una de las variables independientes como son: concentración de aditivo (Elemento vaciado = 0.0090) y el tiempo de fraguado de concreto (Edad del testigo = 28.0). Por ello, se concluyó con el cumplimiento de objetivos general y específicosThe objectives of this thesis was to determines the effect of the plasticizing retarding additives TM – 12 on the compressives strengths of concrete at differents ages of the concretes f'c = 210kg/cm2. For this, a descriptive, correlational and quantitative investigation was carried out. 02 types of concretes weres consideres: Standard Concretes and Experimental Concrete, for the latter two dosages were taken into account with the minimum and maximum percentage of additive. In additions, the number of samples will be 4, for each type of concrete (concentration), at the ages of 7 days, 14 days and 28 days, making a total of 40 specimens. With all this, it was necessary: the optimum and maximum concrete compressive strength that can be obtained (457.9253), for optimal and high values of each of the independent variables such as: additive concentration (Empty element = 0.0090) and the setting time of concrete (Age of the witness = 28.0). Therefore, it was concluded with the fulfillment of general and specific objectivesTesi

Factores de riesgo de injuria renal aguda en pacientes hospitalizados con Covid 19 en el Hospital Nacional Adolfo Guevara Velasco – Essalud Cusco. periodo marzo 2020 – 2022.

Introducción: A fines de 2019, surgió un nuevo coronavirus, este desató una pandemia mundial, el virus daña las células del riñón, las tubulares y los podocitos, lo que provoca lesión renal aguda. 3 Objetivo: Identificar los factores de riesgo de Injuria Renal Aguda en pacientes hospitalizados con COVID 19 en el Hospital Nacional Adolfo Guevara Velasco. Periodo Marzo 2020 – 2022. Materiales y método: Es un estudio analítico de casos y controles. Se utilizó ficha de recolección de datos de las historias clínicas de 250 pacientes hospitalizados con COVID 19 en el Hospital Nacional Adolfo Guevara Velasco, 125 casos y 125 controles. Consideramos casos a los pacientes con el diagnóstico de Injuria Renal Aguda y controles a los pacientes sin Injuria Renal Aguda. Se realizó un análisis univariado y bivariado. Resultados: Los factores de riesgo fueron: sepsis (P= 0.000, OR= 14.40 [Li=6.48; Ls=31.95]), estancias más de 30 días (P= 0.000, OR= 13.94 [Li= 6.28; Ls=30.95]), inmunosupresores (P=0.006; OR= 10.78 [Li= 1.36; Ls=85.56]), vasopresores (P= 0.000, OR= 4.70 [Li= 2.49; Ls= 8.86]), obesidad (P= 0.00; OR= 4.87 [Li= 2.54; Ls= 9.33]), ERC (P= 0.000, OR= 6.46 [Li= 2.16; Ls=19.36], hipertensión Arterial (P= 0.000, OR= 3.43 [Li= 1.99; Ls= 5.89]) y ventilación mecánica (P= 0.001, OR= 2.37 [Li= 1.40; Ls= 4.01]). Conclusiones: El principal factor de riesgo en este estudio fue sepsis. Seguido de estancia hospitalaria > 30 días, inmunosupresores, vasopresores, obesidad, ERC, HTA.Introduction: At the end of At the end of 2019, a new coronavirus emerged, it spread rapidly and became a global pandemic, the virus damages kidney cells, such as tubular cells and podocytes, what causes acute kidney injury.3 Objective: Identify the risk factors for Acute Kidney Injury in patients hospitalized with COVID 19 at the Adolfo Guevara Velasco National Hospital - ESSALUD Cusco. Period March 2020 – 2022. Materials and method: It is an analytical study of cases and controls. A data collection sheet was used from the medical records of 250 patients hospitalized with COVID 19 at the Adolfo Guevara Velasco National Hospital, 125 cases and 125 controls. We considered patients with the diagnosis of Acute Kidney Injury as cases and patients without Acute Kidney Injury as controls. A univariate and bivariate analysis was performed. Results: The risk factors were sepsis (P= 0.000, OR= 14.40 [Li= 6.48; Ls= 31.95, stays longer than 30 days (P= 0.000, OR= 13.94 [Li= 6.28; Ls= 30.95]), Inmunosupppressive (P=0.006; OR= 10.78 [Li= 1.36; Ls=85.56]), vasopressors (P= 0.000, OR= 4.70 [Li= 2.49; Ls= 8.86]), obesity (P= 0.00; OR= 4.87 [Li= 2.54; Ls= 9.33]), CKD (P= 0.000, OR= 6.46 [Li= 2.16; Ls=19.36], Arterial Hypertension (P= 0.000, OR= 3.43 [Li= 1.99; Ls= 5.89]), mechanical ventilation (P= 0.001, OR= 2.37 [Li= 1.40; Ls= 4.01]) y diabetes (P=0.000; OR=1.68 [Li= 1.34; Ls= 2.11]). Conclusions: The main risk factors was sepsis. Followed by prolonged hospital stay, obesity, diabetes mellitus, arterial hypertension, mechanical ventilation

Construction and Characterization of E3-Deleted Bovine Adenovirus Type 3 Expressing Full-Length and Truncated Form of Bovine Herpesvirus Type 1 Glycoprotein gD

AbstractUsing the homologous recombination machinery ofE. coli,a 1.245-kb deletion was introduced in the E3 region of bovine adenovirus 3 (BAV3) genomic DNA cloned in a plasmid. Transfection of the restriction enzyme-excised, linear E3-deleted BAV3 genomic DNA into primary fetal bovine retina cells produced infectious virus (BAV3.E3d), suggesting that all the E3-specific open reading frames are nonessential for virus replicationin vitro. Using a similar approach, we constructed replication-competent (BAV3.E3gD and BAV3.E3gDt) BAV3 recombinant expressing full-length (gD) or truncated (gDt) glycoprotein of bovine herpes virus 1. Recombinant gD and gDt proteins expressed by BAV3.E3gD and BAV3.E3gDt, respectively, were recognized by gD-specific monoclonal antibodies directed against conformational epitopes, suggesting that antigenicity of recombinant gD and gDt was similar to that of the native gD expressed in bovine herpes virus 1-infected cells. Intranasal immunization of cotton rats induced strong gD- and BAV3-specific IgA and IgG immune responses. These results suggest that replication-competent bovine adenovirus 3-based vectors have potential for the delivery of vaccine antigens to the mucosal surfaces of animals

Web Service SWePT: A Hybrid Opinion Mining Approach

[EN] The increasing use of social networks and online sites where people can express their opinions has created a growing interest in Opinion Mining. One of the main tasks of Opinion Mining is to determine whether an opinion is positive or negative. Therefore, the role of the feelings expressed on the web has become crucial, mainly due to the concern of businesses and government to automatically identify the semantic orientation of the views of customers or citizens. This is also a concern, in the area of health to identify psychological disorders. This research focuses on the development of a web application called SWePT (Web Service for Polarity detection in Spanish Texts), which implements the Sequential Minimal Optimization (SMO) algorithm, extracting its features from an affective lexicon in Mexican Spanish. For this purpose, a corpus and an affective lexicon in Mexican Spanish were created. The experiments using three (positive, neutral, negative) and five categories (very positive, positive, neutral, negative, and very negative) allow us to demonstrate the effectiveness of the presented method. SWePT has also been implemented in the Emotion-bracelet interface, which shows the opinion of a user graphically.This work has been partially supported by the Sectorial Fund CONACyT-INEGI: Project with ref. 208471, INFOTEC, Mexico. And, also by the project CNDT-PYR2015-0016, CENIDET, Mexico. The work of the third author was in the framework of the SomEMBED MINECO TIN2015-71147-C2-1-P research project. The National Council for Science and Technology (CONACyT Mexico) has funded the research work of Delia Irazu Hernandez Farias (Grant No. 218109/313683 CVU-369616).Baca-Gomez, YR.; Martínez, A.; Rosso, P.; Estrada Esquivel, H.; Hernandez-Farias, DI. (2016). Web Service SWePT: A Hybrid Opinion Mining Approach. Journal of Universal Computer Science. 22(5):671-690. https://doi.org/10.3217/jucs-022-05-067167169022

Comparison of immune responses in parenteral FaeG DNA primed pigs boosted orally with F4 protein or reimmunized with the DNA vaccine

A

Antimicrobial Effect of Lactobacillus reuteri on Cariogenic Bacteria Streptococcus gordonii, Streptococcus mutans,and Periodontal Diseases Actinomyces naeslundii and Tannerella forsythia

Lactic acid bacteria (LAB) are well known for their beneficial effects on human health in the intestine and immune system; however, there are few studies on the impact they can generate in oral health. The aim of this study was to test and compare in vitro antimicrobial activity of L. reuteri on pathogenic bacteria involved in the formation of dental caries: S. mutans, S. gordonii, and periodontal disease: A. naeslundii and T. forsythia. Also, we determined the growth kinetics of each bacterium involved in this study. Before determining the antimicrobial action of L. reuteri on cariogenic bacteria and periodontal disease, the behavior and cell development time of each pathogenic bacterium were studied. Once the conditions for good cell growth of each of selected pathogens were established according to their metabolic requirements, maximum exponential growth was determined, this being the reference point for analyzing the development or inhibition by LAB using the Kirby Bauer method. Chlorhexidine 0.12 % was positive control. L. reuteri was shown to have an inhibitory effect against S. mutans, followed by T. forsythia and S. gordonii, and a less significant effect against A. naeslundii. Regarding the effect shown by L. reuteri on the two major pathogens, we consider its potential use as a possible functional food in the prevention or treatment of oral diseases

Puntos de alivio: Proyecto de comunicación para mejorar la ruta del paciente del Instituto Nacional de Enfermedades Neoplásicas (INEN)

Si bien la salud es un derecho fundamental de las personas, aún existe una gran brecha para lograr el acceso universal a salud de calidad. A nivel nacional, una de las problemáticas se vincula al cáncer. En dicho sector de atención de salud, uno de los grandes problemas son las necesidades de información de los pacientes con cáncer que asisten al Instituto Nacional de Enfermedades Neoplásicas (INEN) ubicado en Lima. En ese sentido, con el fin de plantear un proyecto comunicacional, se plantean los resultados de un diagnóstico comunicacional que presenta como objetivo principal conocer la información disponible para los pacientes, así como las vivencias y necesidades que tienen durante su ruta en el tratamiento. Entonces, la investigación se centra en analizar los recursos informativos, identificar dificultades de acceso a la información, identificar percepciones y discursos, y evidenciar las funciones de la Oficina de Comunicaciones del Instituto desde un enfoque cualitativo, basado en el uso de entrevistas a profundidad, análisis de contenido y observación no participante, principalmente. Así, desde el enfoque de Comunicación para el Desarrollo, se identifica que hay diversas necesidades de información no cubiertas en los pacientes y que pueden entenderse como ‘puntos de dolor’. Hay tres problemas específicos: desubicación de los pacientes al llegar al INEN por la falta de información completa, necesaria y oportuna; el estado de estrés de los pacientes les dificulta la comprensión de recursos comunicacionales complejos; y, el desconocimiento de las redes de apoyo, sus derechos, y los lugares y procedimientos para reclamar. Es así que, se plantea el proyecto comunicacional “Puntos de Alivio”, el cual busca Contribuir a que los pacientes del INEN gocen de mayor bienestar durante su tránsito por el instituto a través de una experiencia de comunicación empática y articulada, a través del trabajo con la Oficina de Comunicaciones del INEN.Even health is a fundamental right for people, there is still a wide gap to achieve universal health access of good quality. Nationally, one of the problems is related to cancer. In the healthcare sector, one of the big problems is the information needs of cancer patients attending the National Institute of Neoplastic Diseases (INEN, by its acronym in Spanish) located in Lima. Accordingly, in order to propose a communication project, the following text presents first the results of a communicational diagnosis, which main objective is to know the information available to patients, as well as the experiences and needs they have during their treatment route. Then, the research focuses on analyzing information resources, identifying difficulties in accessing information, gathering perceptions and speeches, and demonstrating the functions of the Institute's Office of Communications from a qualitative approach, based on the use of in-depth interviews, content analysis and non-participant observation. Thus, from the Communication for Development approach, it is identified that there are various information needs not met in patients which can be understood as ‘pain points’. There are three specific problems: patient disorientation upon arrival at INEN due to the lack of complete and adequate information given in time; the state of stress of the patients makes it difficult for them to understand complex communication resources; and, the lack of knowledge of support networks, their rights, places and procedures to claim. As a result, the “Relief Points” communication project is proposed, and seeks to help INEN cancer patients enjoy greater wellfare during their transit into and out of the institute through an experience of empathic and articulated communication, with the efforts of the INEN Communications Office.Trabajo de investigació

Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

This paper presents measurements of the $W^+ \rightarrow \mu^+\nu$ and $W^- \rightarrow \mu^-\nu$ cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13