La Necesidad de incorporar en la legislación nacional el régimen separación de patrimonios en la unión de hecho – 2021

El objetivo de la investigación es definir si es necesario incorporar en la legislación nacional el régimen separación de patrimonios en la unión de hecho; los convivientes reconocidos notarialmente o judicialmente solicitan a la SUNARP la inscripción de sustitución de régimen patrimonial a pesar por ley no les corresponde; sin embargo, la SUNARP mediante pleno registral de 2019 autorizó la inscripción de cambio de régimen de los convivientes; por consiguiente, el Tribunal Registral solo resuelve administrativamente las observaciones del operador registral tomando como referencia el acuerdo del pleno; ante este problema la investigación se desarrolló mediante la siguiente metodología: enfoque cualitativo, tipo básica y con diseño de teoría fundamentada, cuyos resultados finales determinaron que a pesar de contar con una norma a nivel registral para inscribir sustitución de régimen patrimonial, la carencia de una norma legal para acceder libremente al régimen de separación de patrimonios, origina confusión del patrimonio de los convivientes, vulneran sus derecho a la igualdad y autonomía de la voluntad para regular sus patrimonios; en conclusión, para que los convivientes accedan al régimen de separación de patrimonios si es necesario incorporar en la legislación nacional el régimen separación de patrimonios en la unión de hech

Cluster abundances and S-Z power spectra: effects of non-Gaussianity and early dark energy

In the standard Lambda CDM cosmological model with a Gaussian primordial density fluctuation field, the relatively low value of the mass variance parameter (sigma_8=0.74{+0.05}{-0.06}, obtained from the WMAP 3-year data) results in a reduced likelihood that the measured level of CMB anisotropy on the scales of clusters is due to the Sunyaev-Zeldovich (S-Z) effect. To assess the feasibility of producing higher levels of S-Z power, we explore two alternative models which predict higher cluster abundance. In the first model the primordial density field has a chi^2_1 distribution, whereas in the second an early dark energy component gives rise to the desired higher cluster abundance. We carry out the necessary detailed calculations of the levels of S-Z power spectra, cluster number counts, and angular 2-point correlation function of clusters, and compare (in a self-consistent way) their predicted redshift distributions. Our results provide a sufficient basis upon which the viability of the three models may be tested by future high quality measurements.Comment: 12 pages, 5 figures, accepted for publication in MNRA

Model-based Fault-tolerant Control to Guarantee the Performance of a Hybrid Wind-Diesel Power System in a Microgrid Configuration

AbstractThis paper presents a comparison of two different adaptive control schemes for improving the performance of a hybrid wind-diesel power system in an islanded microgrid configuration against the baseline controller, IEEE type 1 automatic voltage regulator (AVR). The first scheme uses a model reference adaptive controller (MRAC) with a proportional-integral-derivative (PID) controller tuned by a genetic algorithm (GA) to control the speed of the diesel engine (DE) for regulating the frequency of the power system and uses a classical MRAC for controlling the voltage amplitude of the synchronous machine (SM). The second scheme uses a MRAC with a PID controller tuned by a GA to control the speed of the DE, and a MRAC with an artificial neural network (ANN) and a PID controller tuned by a GA for controlling the voltage amplitude of the SM. Different operating conditions of the microgrid and fault scenarios in the diesel engine generator (DEG) were tested: 1) decrease in the performance of the diesel engine actuator (40% and 80%), 2) sudden connection of 0.5 MW load, and 3) a 3-phase fault with duration of 0.5seconds. Dynamic models of the microgrid components are presented in detail and the proposed microgrid and its fault-tolerant control (FTC) are implemented and tested in the Simpower Systems of MATLAB/Simulink® simulation environment. The simulation results showed that the use of ANNs in combination with model-based adaptive controllers improves the FTC system performance in comparison with the baseline controller

Déterminants socioéconomiques de la fréquence des relations sexuelles dans la population universitaire.

This research analyze socioeconomic factors, and sexuality awareness among undergraduate students in order to evaluate the implementation (or not) of prevention public campaigns associated to sexuality. Results indicate that age of individuals, their starting age of sexual activity, alcohol consumption and family planning affect sexual relations frequency of undergraduate students. In addition, youngsters consider most the risks of unwanted pregnancy than sexually trasnmitted diseases.El objetivo de este documento es evaluar algunos factores socioeconómicos, de índole social y en especial del grado de conocimiento y sensibilidad alrededor del tema de la sexualidad de la población joven universitaria, con la finalidad de brindar soporte a la necesidad o no de la puesta en marcha de campañas de prevención de factores de riesgo asociados a la actividad sexual. Los resultados indican que la edad del individuo, la edad de inicio de las relaciones sexuales, el consumo de alcohol y la puesta en práctica de técnicas de planificación, inciden en la frecuencia sexual de los jóvenes universitarios. Se concluye que la población joven pondera en mayor medida los riesgos a tener un embarazo no deseado que a las enfermedades de transmisión sexual.Cette recherche analyse les facteurs socioéconomiques et la sensibilisation à la sexualité chez les étudiants de premier cycle afin d’évaluer la mise en œuvre (ou non) de campagnes publiques de prévention associées à la sexualité. Les résultats indiquent que l’âge des individus, leur âge de début d’activité sexuelle, la consommation d’alcool et la planification familiale affectent la fréquence des relations sexuelles des étudiants de premier cycle. En outre, les jeunes considèrent plus les risques de grossesse non désirée que les maladies sexuellement transmissibles

What is an emerging technology?

There is considerable and growing interest in the emergence of novel technologies, especially from the policy-making perspective. Yet as an area of study, emerging technologies lacks key foundational elements, namely a consensus on what classifies a technology as ’emergent’ and strong research designs that operationalize central theoretical concepts. The present paper aims to fill this gap by developing a definition of ’emerging technologies’ and linking this conceptual effort with the development of a framework for the operationalisation of technological emergence. The definition is developed by combining a basic understanding of the term and in particular the concept of ’emergence’ with a review of key innovation studies dealing with definitional issues of technological emergence. The resulting definition identifies five attributes that feature in the emergence of novel technologies. These are: (i) radical novelty, (ii) relatively fast growth, (iii) coherence, (iv) prominent impact, and (v) uncertainty and ambiguity. The framework for operationalising emerging technologies is then elaborated on the basis of the proposed attributes. To do so, we identify and review major empirical approaches (mainly in, although not limited to, the scientometric domain) for the detection and study of emerging technologies (these include indicators and trend analysis, citation analysis, co-word analysis, overlay mapping, and combinations thereof) and elaborate on how these can be used to operationalise the different attributes of emergence

Are There Gains to Joining a Union? Evidence from Mexico

Union density in Mexico has been in decline since the 1980s. This article provides evidence on the worker compensation gains (losses) made by males upon joining (leaving) a union. These are estimated using a nationally representative labour market survey covering 2005q1–2016q1. The transitions between non‐union and union status are investigated using a difference‐in‐difference estimator. The findings suggest that joining a union is associated with modest wage gains, contrary to what the literature has shown for most industrialized nations. However, in contrast to this, some union leavers are found to experience a decrease in wages. This article also contributes to the wider literature by providing the first estimates of the longitudinal gain (loss) associated with joining (leaving) a union with respect to non‐wage benefits. The findings show joining (leaving) a union increases (decreases) the probability of being in receipt of legally guaranteed benefits such as bonuses and paid holidays. This suggests that although union density may be in decline, unions still have an important role to play in voicing worker's preferences with respect to compensation and ensuring that employers comply with the law

Role of frailty assessment in patients undergoing cardiac interventions.

Average life expectancy is increasing in the western world resulting in a growing number of frail individuals with coronary heart disease, often associated with comorbidities. Decisions to proceed to invasive interventions in elderly frail patients is challenging because they may gain benefit, but are also at risk of procedure-related complications. Current risk scores designed to predict mortality in cardiac procedures are mainly based on clinical and angiographic factors, with limitations in the elderly because they are mainly derived from a middle-aged population, do not account for frailty and do not predict the impact of the procedure on quality of life which often matters more to elderly patients than mortality. Frailty assessment has emerged as a measure of biological age that correlates well with quality of life, hospital admissions and mortality. Potentially, the incorporation of frailty into current risk assessment models will cause a shift towards more appropriate care. The need for a more accurate method of risk stratification incorporating frailty, particularly for elderly patients is pressing. This article reviews the association between frailty and cardiovascular disease, the impact of frailty on outcomes of cardiac interventions and suggests ways in which frailty assessment could be incorporated into cardiology clinical practice

Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis

OBJECTIVE: Hepatic stellate cells (HSC) transdifferentiation into myofibroblasts is central to fibrogenesis. Epigenetic mechanisms, including histone and DNA methylation, play a key role in this process. Concerted action between histone and DNA-mehyltransferases like G9a and DNMT1 is a common theme in gene expression regulation. We aimed to study the efficacy of CM272, a first-in-class dual and reversible G9a/DNMT1 inhibitor, in halting fibrogenesis. DESIGN: G9a and DNMT1 were analysed in cirrhotic human livers, mouse models of liver fibrosis and cultured mouse HSC. G9a and DNMT1 expression was knocked down or inhibited with CM272 in human HSC (hHSC), and transcriptomic responses to transforming growth factor-β1 (TGFβ1) were examined. Glycolytic metabolism and mitochondrial function were analysed with Seahorse-XF technology. Gene expression regulation was analysed by chromatin immunoprecipitation and methylation-specific PCR. Antifibrogenic activity and safety of CM272 were studied in mouse chronic CCl4 administration and bile duct ligation (BDL), and in human precision-cut liver slices (PCLSs) in a new bioreactor technology. RESULTS: G9a and DNMT1 were detected in stromal cells in areas of active fibrosis in human and mouse livers. G9a and DNMT1 expression was induced during mouse HSC activation, and TGFβ1 triggered their chromatin recruitment in hHSC. G9a/DNMT1 knockdown and CM272 inhibited TGFβ1 fibrogenic responses in hHSC. TGFβ1-mediated profibrogenic metabolic reprogramming was abrogated by CM272, which restored gluconeogenic gene expression and mitochondrial function through on-target epigenetic effects. CM272 inhibited fibrogenesis in mice and PCLSs without toxicity. CONCLUSIONS: Dual G9a/DNMT1 inhibition by compounds like CM272 may be a novel therapeutic strategy for treating liver fibrosis