Spontaneous iliopsoas muscle hematoma in a patient with von Willebrand disease: a case report

Abstract Introduction Iliopsoas hemorrhage is a serious complication of bleeding disorders that occurs most commonly in patients with hemophilia and less commonly in patients with von Willebrand disease. It causes severe pain, muscle dysfunction and occasionally femoral nerve palsy. We describe the case of a patient with von Willebrand disease type 3 with a large iliopsoas hematoma who was treated with a von Willebrand factor concentrate (Humate-P). Case presentation A 20-year-old Iranian man was referred to our emergency ward because of the gradual onset of right flank pain. He was known to have been diagnosed with von Willebrand disease type 3 at age two years old. Magnetic resonance imaging showed a mass in the right iliopsoas muscle. The diagnosis of iliopsoas hemorrhage and partial femoral nerve palsy was established, and he responded to medical treatment. Conclusion We report a case of von Willebrand disease type 3 with spontaneous iliopsoas hematoma associated with femoral nerve palsy that was well managed with Humate-P treatment.</p

Adrenal extramedullary hematopoiesis associated with β-thalassemia major

The presence of apparently normal hematopoietic tissue outside of bone marrow cavity is defined as extramedullary hema - topoiesis (EMH). EMH is a rare complication in thalassemia major (TM) and adrenal gland as well. This report describes a case of adrenal EMH in a 26-year-old man with β-TM. He has been transfused with regular blood transfusion since 9 months. During the routine physical examination he was incidentally found to have a hypoechoic mass at his abdominal ultrasonography. Abdominal computed tomography scan revealed a right well-defined suprarenal mass 7.7¥7.3¥5.8 cm in size. The diagnosis of EMH was confirmed with ultrasonographic-guided fine needle biopsy. Treatment options which include intensified regular blood transfusion and hydroxyurea have been started

Recent advances in using nanofluids in renewable energy systems and the environmental implications of their uptake

It has been more than two decades since the discovery of ‘nanofluids’ – mixtures of common liquids and solid nanoparticles with at least one dimension below 100 nm in size. While colloidal suspensions of particles (which include larger particles) have been studied for several decades, the term ‘nanofluids’ designates fluid systems that have enhanced thermal and optical properties. Although barriers to their commercial adoption remain, the field of nanofluids has continued to grow. Many studies have considered the effects of adding nanoparticles on the thermal efficiency and exergy efficiency of renewable energy systems particularly solar systems, however, few have investigated their potential for emission reductions. Critically, since renewable energy technologies aim to reduce the environmental impact of energy systems, this review focuses on whether nanofluids provide a net environmental benefit. Thus, in addition to providing a comprehensive overview of this body of literature from an environmental perspective, this review also highlights areas for future work that could help ensure that nanofluids have a net positive environmental impact in renewable energy systems going forward