Constraints on North Anatolian Fault Zone Width in the Crust and Upper Mantle From S Wave Teleseismic Tomography

We present high-resolution S wave teleseismic tomography images of the western segment of the North Anatolian Fault Zone (NAFZ) in Turkey using teleseismic data recorded during the deployment period of the Dense Array for Northern Anatolia array. The array comprised 66 stations with a nominal station spacing of 7 km, thus permitting a horizontal and vertical resolution of approximately 15 km. We use the current S wave results with previously published P wave teleseismic tomography to produce maps of relative VP/VSanomalies, which we use to highlight the difference in overall composition of the three terranes separated by the northern (NNAF) and southern branches of the NAFZ. Our results show a narrow S wave low-velocity anomaly beneath the northern branch of the NAFZ extending from the upper crust, where it has a width of ∼10 km, to the lower crust, where it widens to ∼30 km. This low-velocity zone most likely extends into the upper mantle, where we constrain its width to be ≤ 50 km and interpret it as indicative of localized shear beneath the NNAF; this structure is similar to what has been observed for the NAFZ west of 32°, and therefore, we propose that the structure of the NNAF is similar to that of the NAFZ in the east. The southern branch of the NAFZ does not show a very strong signature in our images, and we conclude that it is most likely rooted in the crust, possibly accommodating deformation related to rotation of the Armutlu/Almacik Blocks situated between the two NAFZ branches

Gas emissions and active tectonics within the submerged section of the North Anatolian Fault zone in the Sea of Marmara

The submerged section of the North Anatolian fault within the Marmara Sea was investigated using acoustic techniques and submersible dives. Most gas emissions in the water column were found near the surface expression of known active faults. Gas emissions are unevenly distributed. The linear fault segment crossing the Central High and forming a seismic gap – as it has not ruptured since 1766, based on historical seismicity, exhibits relatively less gas emissions than the adjacent segments. In the eastern Sea of Marmara, active gas emissions are also found above a buried transtensional fault zone, which displayed micro-seismic activity after the 1999 events. Remarkably, this zone of gas emission extends westward all along the southern edge of Cinarcik basin, well beyond the zone where 1999 aftershocks were observed. The long term monitoring of gas seeps could hence be highly valuable for the understanding of the evolution of the fluid-fault coupling processes during the earthquake cycle within the Marmara Sea

Gas and seismicity within the Istanbul seismic gap

Understanding micro-seismicity is a critical question for earthquake hazard assessment. Since the devastating earthquakes of Izmit and Duzce in 1999, the seismicity along the submerged section of North Anatolian Fault within the Sea of Marmara (comprising the “Istanbul seismic gap”) has been extensively studied in order to infer its mechanical behaviour (creeping vs locked). So far, the seismicity has been interpreted only in terms of being tectonic-driven, although the Main Marmara Fault (MMF) is known to strike across multiple hydrocarbon gas sources. Here, we show that a large number of the aftershocks that followed the M 5.1 earthquake of July, 25th 2011 in the western Sea of Marmara, occurred within a zone of gas overpressuring in the 1.5–5 km depth range, from where pressurized gas is expected to migrate along the MMF, up to the surface sediment layers. Hence, gas-related processes should also be considered for a complete interpretation of the micro-seismicity (~M < 3) within the Istanbul offshore domain

Hydrology in the Sea of Marmara during the last 23 ka : implications for timing of Black Sea connections and sapropel deposition

Author Posting. © American Geophysical Union, 2010. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Paleoceanography 25 (2010): PA1205, doi:10.1029/2009PA001735.Sediments deposited under lacustrine and marine conditions in the Sea of Marmara hold a Late Quaternary record for water exchange between the Black Sea and the Mediterranean Sea. Here we report a multiproxy data set based on oxygen and strontium isotope results obtained from carbonate shells, major and trace elements, and specific organic biomarker measurements, as well as a micropaleontological study from a 14C-dated sediment core retrieved from the Sea of Marmara. Pronounced changes occurred in δ18O and 87Sr/86Sr values at the fresh and marine water transition, providing additional information in relation to micropaleontological data. Organic biomarker concentrations documented the marine origin of the sapropelic layer while changes in n-alkane concentrations clearly indicated an enhanced contribution for organic matter of terrestrial origin before and after the event. When compared with the Black Sea record, the results suggest that the Black Sea was outflowing to the Sea of Marmara from the Last Glacial Maximum until the warmer Bølling-Allerød. The first marine incursion in the Sea of Marmara occurred at 14.7 cal ka B.P. However, salinification of the basin was gradual, indicating that Black Sea freshwaters were still contributing to the Marmara seawater budget. After the Younger Dryas (which is associated with a high input of organic matter of terrestrial origin) both basins were disconnected, resulting in a salinity increase in the Sea of Marmara. The deposition of organic-rich sapropel that followed was mainly related to enhanced primary productivity characterized by a reorganization of the phytoplankton population.We acknowledge support from INSU and the French Polar Institute IPEV

Adaptive independent sticky MCMC algorithms

Monte Carlo methods have become essential tools to solve complex Bayesian inference problems in different fields, such as computational statistics, machine learning, and statistical signal processing. In this work, we introduce a novel class of adaptive Monte Carlo methods, called adaptive independent sticky Markov Chain Monte Carlo (MCMC) algorithms, to sample efficiently from any bounded target probability density function (pdf). The new class of algorithms employs adaptive non-parametric proposal densities, which become closer and closer to the target as the number of iterations increases. The proposal pdf is built using interpolation procedures based on a set of support points which is constructed iteratively from previously drawn samples. The algorithm’s efficiency is ensured by a test that supervises the evolution of the set of support points. This extra stage controls the computational cost and the convergence of the proposal density to the target. Each part of the novel family of algorithms is discussed and several examples of specific methods are provided. Although the novel algorithms are presented for univariate target densities, we show how they can be easily extended to the multivariate context by embedding them within a Gibbs-type sampler or the hit and run algorithm. The ergodicity is ensured and discussed. An overview of the related works in the literature is also provided, emphasizing that several well-known existing methods (like the adaptive rejection Metropolis sampling (ARMS) scheme) are encompassed by the new class of algorithms proposed here. Eight numerical examples (including the inference of the hyper-parameters of Gaussian processes, widely used in machine learning for signal processing applications) illustrate the efficiency of sticky schemes, both as stand-alone methods to sample from complicated one-dimensional pdfs and within Gibbs samplers in order to draw from multi-dimensional target distributions

Imaging of subsurface lineaments in the southwestern part of the Thrace Basin from gravity data

Linear anomalies, as an indicator of the structural features of some geological bodies, are very important for the interpretation of gravity and magnetic data. In this study, an image processing technique known as the Hough transform (HT) algorithm is described for determining invisible boundaries and extensions in gravity anomaly maps. The Hough function implements the Hough transform used to extract straight lines or circles within two-dimensional potential field images. It is defined as image and Hough space. In the Hough domain, this function transforms each nonzero point in the parameter domain to a sinusoid. In the image space, each point in the Hough space is transformed to a straight line or circle. Lineaments are depicted from these straight lines which are transformed in the image domain. An application of the Hough transform to the Bouguer anomaly map of the southwestern part of the Thrace Basin, NW Turkey, shows the effectiveness of the proposed approach. Based on geological data and gravity data, the structural features in the southwestern part of the Thrace Basin are investigated by applying the proposed approach and the Blakely and Simpson method. Lineaments identified by these approaches are generally in good accordance with previously-mapped surface faults

Reconciling the stratigraphy and depositional history of the Lycian orogen-top basins, SW Anatolia

Terrestrial fossil records from the SWAnatolian basins are crucial both for regional correlations and palaeoenvironmental reconstructions. By reassessing biostratigraphic constraints and incorporating new fossil data, we calibrated and reconstructed the late Neogene andQuaternary palaeoenvironments within a regional palaeogeographical framework. The culmination of the Taurides inSWAnatolia was followed by a regional crustal extension from the late Tortonian onwards that created a broad array of NE-trending orogen-top basins with synchronic associations of alluvial fan, fluvial and lacustrine deposits. The terrestrial basins are superimposed on the upper Burdigalian marine units with a c. 7 myr of hiatus that corresponds to a shift from regional shortening to extension. The initial infill of these basins is documented by a transition from marginal alluvial fans and axial fluvial systems into central shallow-perennial lakes coinciding with a climatic shift from warm/humid to arid conditions. The basal alluvial fan deposits abound in fossil macro-mammals of an early Turolian (MN11–12; late Tortonian) age. The Pliocene epoch in the region was punctuated by subhumid/humid conditions resulting in a rise of local base levels and expansion of lakes as evidenced by marsh-swamp deposits containing diverse fossilmammal assemblages indicating late Ruscinian (lateMN15; late Zanclean) ageWe are grateful for the support of the international bilateral project between The Scientific and Technological Research Council of Turkey (TUBITAK) and The Russian Scientific Foundation (RFBR) with grant a number of 111Y192. M.C.A. is grateful to the Turkish Academy of Sciences (TUBA) for a GEBIP (Young Scientist Award) grant. T.K. and S.M. are grateful to the Ege University Scientific Research Center for the TTM/002/2016 and TTM/001/2016 projects. M.C.A., H.A., S.M. and M.B. have obtained Martin and Temmick Fellowships at Naturalis Biodiversity Center (Leiden). F.A.D. is supported by a Mehmet Akif Ersoy University Scientific Research Grant. T.A.N. is supported by an Alexander-von-Humboldt Scholarship. L.H.O. received support from TUBITAK under the 2221 program for visiting scientists

The stratigraphic architecture and evolution of the Burdigalian carbonate—siliciclastic sedimentary systems of the Mut Basin, Turkey

This study describes the coeval development of the depositional environments in three areas across the Mut Basin (Southern Turkey) throughout the Late Burdigalian (early Miocene). Antecedent topography and rapid high-amplitude sea-level change are the main controlling factors on stratigraphic architecture and sediment type. Stratigraphic evidence is observed for two high-amplitude (100–150 m) sea-level cycles in the Late Burdigalian to Langhian. These cycles are interpreted to be eustatic in nature and driven by the long-term 400-Ka orbital eccentricity-cycle-changing ice volumes in the nascent Antarctic icecap. We propose that the Mut Basin is an exemplary case study area for guiding lithostratigraphic predictions in early Miocene shallow-marine carbonate and mixed environments elsewhere in the world. The Late Burdigalian in the Mut Basin was a time of relative tectonic quiescence, during which a complex relict basin topography was flooded by a rapid marine transgression. This area was chosen for study because it presents extraordinary large-scale 3D outcrops and a large diversity of depositional environments throughout the basin. Three study transects were constructed by combining stratal geometries and facies observations into a high-resolution sequence stratigraphic framework. 3346 m of section were logged, 400 thin sections were studied, and 145 biostratigraphic samples were analysed for nannoplankton dates (Bassant, P., 1999. The high-resolution stratigraphic architecture and evolution of the Burdigalian carbonate-siliciclastic sedimentary systems of the Mut Basin, Turkey. PhD Thesis. GeoFocus 3. University of Fribourg, 277 p.). The first transect (Alahan) is on the northwestern basin margin. Here, the siliciclastic input is high due to the presence of a river system. The siliciclastic depocentre migrates landwards during transgressions, creating an ecological window allowing carbonates to develop in the distal part of the delta. Carbonate production shuts down during the regression when siliciclastics return. The second transect (Pirinç) is also situated on the northern basin margin 12 km to the east of the Alahan section. It shows a complete platform-to-basin transition. An isolated carbonate platform complex develops during the initial flooding, which is drowned during a time of rapid sea-level rise and environmental stress, associated with prograding siliciclastics. The shelf margin then retrogrades forming large-scale clinoform geometries and progrades before a major sea-level fall provokes slumping collapse, followed by rebuilding of the shelf margin as sea level rises again. The third transect (Silifke) has a steep asymmetric Pre-Miocene valley-topography, forming a narrow strait, linking the Mut Basin to the Mediterranean. Strong tidal currents are generated in this strait area. Siliciclastic input is low and localised. Eighty metres of cross-bedded bioclastic sands are deposited in a tidal regime at the base. Subsequently, carbonate platforms backstep against the shallow-dipping northern flank, while platforms only develop on the steep southern flank when a firm wide shallow-marine substrate is provided by a bench on the footwall block. The energy of the environment decreases with increased flooding of the strait area. Third-order sequences and higher-order parasequences have been identified in each transect and correlated between transects. Correlations were made using biostratigraphic data and high-resolution sequence stratigraphy in combination with the construction of the relative sea-level curve for each site. The third-order highstands are stacked in a proximal position and separated by exposure surfaces, while the lowstands, deposited in a distal setting, are separated by deep-marine (offshore or subphotic) deposits. The parasequences produce dominantly aggradational and progradational geometries with transgressive ravinement surfaces and exposure surfaces developing at times. Reconstruction of the depositional profile shows that the third-order sequences are driven by relative sea-level oscillations of 100–150 m, and that these may be attributed to 400-Ka orbital eccentricity cycles. The parasequences are driven by eustatic 20–30 m sea-level oscillations, which may be attributed to the 100-Ka orbital eccentricity cycles. The isolated carbonate build-ups in the Pirinç and Alahan transects develop at the same time as bioclastic tidal deposits in the Silifke area during the transgression of sequence 1. This is caused by a difference in hydrodynamic regime: a direct result of basin morphology funneling tidal currents in the Silifke area. We also demonstrate how during the highstands a siliciclastic delta system progrades in the Alahan area, while only 12 km to the east, a fringing carbonate platform develops, showing how siliciclastic input can have a very localised effect on carbonate environments. The exceptional quality of the outcrops with its variety of environments and its location at the Tethyan margin make this site a good candidate for a reference model for Burdigalian reef and platform architectures

TCR gene therapy for cancer

The protocol describes the procedure of antigen-specific T cell generation and TCR identification for the use in adoptive T cell therapy. We describe two paths of generating antigen-specific T cells, first, T cell stimulation with autologous dendritic cells pulsed with antigen peptide, second, in vivo T cell stimulation with peptide or DNA by gene gun application in a suitable mouse model followed by in vitro enrichment of peptide-reactive T cells. Peptide-stimulated T cells are sorted by fluorescence-activated cell sorting for CD107α or IFNγ expression and subsequently isolated RNA is used in a 5' rapid amplification of cDNA ends (RACE )-PCR specific for TCR for TCR chain identification. After retroviral cloning, it is re-expressed on human T cells to test its applicability in adoptive T cell therapy