259 research outputs found

    Satisfacción laboral del personal del servicio de Farmacia del Centro Médico Naval “CMST” - Bellavista 2021

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    Objetivo: El propósito de este estudio es identificar el nivel de satisfacción laboral entre los trabajadores del Centro Médico Naval “Cirujano Mayor Santiago Távara” en relación con los factores ambientales, sociodemográficos e individuales, de forma tal que permita diseñar y/o elaborar planes que introduzcan mejoras que redunden en la calidad del servicio prestado por los servidores del área de farmacia del referido nosocomio. Material y métodos: Veintiséis farmacéuticos de hospital fueron incluidos en la investigación. Se utilizó la Escala de Satisfacción Laboral para medir el nivel de satisfacción con su trabajo actual, y el TAS-20 para evaluar la experiencia y la conciencia emocional. A partir de los criterios expuestos, el tipo de investigación que se adecuó más al presente trabajo, fue el cuantitativo. A partir de ese enfoque, se determinó la mensura de las variables consideradas en el estudio. El método que se seleccionó fue el descriptivo con corte transversal. En cuanto al diseño el estudio es transversal y expost-facto. Los datos se analizaron con la versión 25 de IBM SPSS Statistics. Resultados: Los análisis de los datos revelaron un bajo nivel de satisfacción con respecto a la subescala de remuneración-promoción, un alto nivel de satisfacción con respecto a la dimensión dirección-relaciones interpersonales y un alto nivel de satisfacción con respecto a la subescala organización-comunicación. El 74% de los encuestados está insatisfecho con el presupuesto anual y el 86,3% no está nada satisfecho con la legislación actual. Conclusiones: Estos resultados son importantes para los farmacéuticos de dicho centro hospitalario y para la dirección del hospital, con el fin de enfocar las políticas sanitarias, la gestión y los aspectos ambientales, con el propósito de aumentar el nivel de satisfacción de los farmacéuticos del hospital.http://repositorio.unid.edu.pe/handle/unid/341?show=ful

    Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study

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    : The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135-15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359-5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138-5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184-5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598-9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090-6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286-5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p < 0.001; 95% CI 1.912-7.442; aOR 3.772), whereas endoscopic drainage of pancreatic necrosis (p = 0.018; 95% CI 0.138-0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143-0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible. Study protocol registered in ClinicalTrials.Gov (I.D. Number NCT04747990)

    Evaluación de parámetros productivos y económicos en la alimentación de porcinos en engorda

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    The objective was to evaluate the production cost for pigs in different stages from farrow-to-finish that were fed with commercial and not commercial diets. 28 Landrace-Yorkshire pigs were used (males and females) at an initial weight of 14.028 ± 2.587 kg and were distributed in three diets: 1) commercial feed 1; 2) commercial feed 2; and 3) not commercial feed. The experiment was developed for 86 days. The evaluated variables for each one of the production stages were: initiation weight gain (IWG), final weight gain (FWG), daily weight gain (DWG), feed conversion (FC) and the cost of the feed for kg of live weight gained (/kgLWG).Thedatawasanalyzedthroughavarianceanalysisafterarandomizeddesign,usingtheinitialweightascovariable.Therewerenosignificantdifferencesinthestudiedvariablesatthefirstfatteningandsecondfatteningstages(P>0.05).Atthedevelopmentstage,diet2(commercialfeed2)wasthemostefficient(P<0.05).ButtherewasnodifferenceinFCbetweentreatment2and3,anditwasthelowestinT1.Feedcostperkgofweightgainwaslowerwithdiet3comparedtodiet1and2atstarting,growingandfinishingstage.Itisconcludedthatinthesameconditions,itisfeasibletomakeacompletefeedformulabasedonavailablerawmaterialsthatcoversalltheporcinerequirementsmaintainingtheproductivevariablesatalowercostcomparedtothecommercialfeeds.Elobjetivofueevaluarelcomportamientoproductivoycostoalimenticiodeporcinosendiferentesetapas,alimentadoscondietascomercialesyunanocomercial.Seutilizaron28lechones(hembrasymachos)F1LandracexYorkshireconunpesoinicialpromediode14.028±2.587kg,distribuidosaleatoriamenteentresdietasexperimentales:1)comercial1;2)comercial2;y3)nocomercial.Elexperimentosedesarrolloˊdurante86dıˊas,ofreciendoelalimentoalibreaccesopreviamentepesadoymidiendolorechazado.Lasvariablesevaluadasfueron:gananciadiariadepesoporetapas:[iniciacioˊn(GDPI),desarrollo(GDPD)yfinalizacioˊn(GDPF)];conversioˊnalimenticiaporetapas(CA)yelcostodealimentacioˊnporkilogramodepesovivoproducidoporetapas(/kg LWG). The data was analyzed through a variance analysis after a randomized design, using the initial weight as covariable. There were no significant differences in the studied variables at the first fattening and second fattening stages (P>0.05). At the development stage, diet 2 (commercial feed 2) was the most efficient (P<0.05). But there was no difference in FC between treatment 2 and 3, and it was the lowest in T1. Feed cost per kg of weight gain was lower with diet 3 compared to diet 1 and 2 at starting, growing and finishing stage. It is concluded that in the same conditions, it is feasible to make a complete feed formula based on available raw materials that covers all the porcine requirements maintaining the productive variables at a lower cost compared to the commercial feeds.El objetivo fue evaluar el comportamiento productivo y costo alimenticio de porcinos en diferentes etapas, alimentados con dietas comerciales y una no comercial. Se utilizaron 28 lechones (hembras y machos) F1 Landrace x Yorkshire con un peso inicial promedio de 14.028 ± 2.587 kg, distribuidos aleatoriamente en tres dietas experimentales: 1) comercial 1; 2) comercial 2; y 3) no comercial. El experimento se desarrolló durante 86 días, ofreciendo el alimento a libre acceso previamente pesado y midiendo lo rechazado. Las variables evaluadas fueron: ganancia diaria de peso por etapas: [iniciación (GDPI), desarrollo (GDPD) y finalización (GDPF)]; conversión alimenticia por etapas (CA) y el costo de alimentación por kilogramo de peso vivo producido por etapas (/kg PVP). Los datos fueron analizados con análisis de varianza bajo un diseño completamente al azar, utilizando peso inicial como covariable. Para GDPD, comercial 2 resultó ser más eficiente 906±129 gr (P<0.05). Para CA no hubo diferencia entre comercial 2 y no comercial, 2.68 y 2.61 respectivamente, siendo diferente comercial 1 2.94 (P<0.05). El $/kg de PVP (MN) en las etapas de iniciación, desarrollo y finalización, 9.42, 10.12 y 15.97 fue menor en la dieta no comercial (P<0.05). Con las condiciones de este experimento se obtuvieron resultados similares con la dieta no comercial y las dietas comerciales en las ganancias diarias de peso en las etapas de iniciación y finalización, 634 y 945 gramos respectivamente; para CA en iniciación fue similar con las dietas comerciales 1 y 2, en desarrollo fue similar con la comercial 2, y en finalización fue mejor la dieta no comercial; en el costo alimenticio la dieta no comercial fue mejor en iniciación y finalización, y similar con la dieta comercial 2 en la etapa de desarrollo

    EFFECT OF EXOGENOUS GLUTAMATE SUPPLY ON THE ONSET OF PUBERTY IN GOATS: I. SERUM LEVELS OF INSULIN

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    Glutamate, the main neuroexcitatory amino acid of the central nervous system has a marked stimulatory effect on the reproductive axis in mammals. Precocious puberty occurs in response to glutamate administration in several mammals. The aim of this study was to evaluate the effect of exogenous glutamate supply upon the onset of puberty and possible links to changes in serum insulin levels in prepuberal goats. . The study was carried out in northern Mexico at the Southern Goat Research Unit, URUZA-UACH (26° NL, 103° WL, 1,117 m altitude), from June to September. Three-month-old 7/8 Saanen-1/8 Criollo goats (n=18) were fed a diet formulated to met 120% of their nutritional requirements, adjusted for live weight (LW). Both LW and body condition score (BCS) were registered every 15 days prior to feeding. In June, goats were randomly allocated to two experimental groups: 1). Excitatory amino acids (AA, n=10; 16.52±1.04 kg, 3.4±0.12 BCS) and 2). Control, (CC, n=8; 16.1±1.04 kg, 3.1±0.12 BCS). The AA group received an intravenous infusion of 7 mg kg-1 LW of L-glutamate, while the C group received saline. From mid-June to late September, blood samples were obtained from all goats once a week, to asses P4, by RIA. Goats with serum P4 levels ≥ 1 ng mL-1 in two consecutive blood samples were considered reproductively active,(onset of puberty). Comparisons between groups for both LW and BCS were made using ANOVA-CRD. Percentage of goats depicting or not ovarian activity was tested with a Xi2 analysis. The initial averages for LW and BCS were 16.65±1.04 kg, and 3.31±0.12 units, with no differences (P>0.05) between treatments. Goats in the AA group showed earlier (

    EFFECT OF EXOGENOUS GLUTAMATE SUPPLY ON THE ONSET OF PUBERTY IN GOATS. II. SERUM LEVELS OF TRIIODOTHYRONINE

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    Thyroid hormones and their receptors in the ovaries are active regulators of reproductive function; both hyper- and hypo-thyroidism may result in estrous cycle disturbances. In addition, thyroid hormones elicit an extraordinary multiplicity of biochemical, cellular, and physiological responses, both in the simplest and the most complex organisms. On the other hand, glutamate, the main excitatory amino acid of the central nervous system has a marked stimulatory effect on the reproductive axis in mammals. In fact, occurrence of precocious puberty in response to administration of glutamate agonists has been reported in several species. The aim of the present study was to evaluate the effect of administration of glutamate on the onset of puberty in goats, and the association with serum triiodothyronine levels (T3), as a possible metabolic signal for the onset of ovarian activity in juvenile goats. The study was carried out in northern Mexico (26Ëš N) from June to October. Goats (n=18) were offered alfalfa hay (14% PC; 1.14 Mkal Kg-1 ENm), corn silage (8.1% PC, 1.62 ENm Mcal kg-1), and ground corn grain (11.2% PC, 2.38 ENm Mcal kg-1) under natural photoperiod. Location, animals, treatment design, preparation of the glutamate buffer solution, blood sampling scheme and quantification of serum P4 were described in the first part of this study. Serum samples were also evaluated for their content of T3 by RIA. Final averages for live weight (LW) and body condition score (BCS) did not differ (P>0.05) between the Glutamate-supplemented and control groups (23.7±0.72 vs. 22.7±0.72 kg) and (3.69±0.10 vs. 3.38±0.10 units), respectively. The overall average for T3 during the study was 1.47 ng mL-1, with higher levels (

    Multiplicity dependence of light (anti-)nuclei production in p–Pb collisions at sNN=5.02 TeV

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    The measurement of the deuteron and anti-deuteron production in the rapidity range −1 < y < 0 as a function of transverse momentum and event multiplicity in p–Pb collisions at √sNN = 5.02 TeV is presented. (Anti-)deuterons are identified via their specific energy loss dE/dx and via their time-of- flight. Their production in p–Pb collisions is compared to pp and Pb–Pb collisions and is discussed within the context of thermal and coalescence models. The ratio of integrated yields of deuterons to protons (d/p) shows a significant increase as a function of the charged-particle multiplicity of the event starting from values similar to those observed in pp collisions at low multiplicities and approaching those observed in Pb–Pb collisions at high multiplicities. The mean transverse particle momenta are extracted from the deuteron spectra and the values are similar to those obtained for p and particles. Thus, deuteron spectra do not follow mass ordering. This behaviour is in contrast to the trend observed for non-composite particles in p–Pb collisions. In addition, the production of the rare 3He and 3He nuclei has been studied. The spectrum corresponding to all non-single diffractive p-Pb collisions is obtained in the rapidity window −1 < y < 0 and the pT-integrated yield dN/dy is extracted. It is found that the yields of protons, deuterons, and 3He, normalised by the spin degeneracy factor, follow an exponential decrease with mass number

    A community-derived classification for extant lycophytes and ferns

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    Phylogeny has long informed pteridophyte classification. As our ability to infer evolutionary trees has improved, classifications aimed at recognizing natural groups have become increasingly predictive and stable. Here, we provide a modern, comprehensive classification for lycophytes and ferns, down to the genus level, utilizing a community-based approach. We use monophyly as the primary criterion for the recognition of taxa, but also aim to preserve existing taxa and circumscriptions that are both widely accepted and consistent with our understanding of pteridophyte phylogeny. In total, this classification treats an estimated 11 916 species in 337 genera, 51 families, 14 orders, and two classes. This classification is not intended as the final word on lycophyte and fern taxonomy, but rather a summary statement of current hypotheses, derived from the best available data and shaped by those most familiar with the plants in question. We hope that it will serve as a resource for those wanting references to the recent literature on pteridophyte phylogeny and classification, a framework for guiding future investigations, and a stimulus to further discourse

    A community-derived classification for extant lycophytes and ferns

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    Phylogeny has long informed pteridophyte classification. As our ability to infer evolutionary trees has improved, classifications aimed at recognizing natural groups have become increasingly predictive and stable. Here, we provide a modern, comprehensive classification for lycophytes and ferns, down to the genus level, utilizing a community-based approach. We use monophyly as the primary criterion for the recognition of taxa, but also aim to preserve existing taxa and circumscriptions that are both widely accepted and consistent with our understanding of pteridophyte phylogeny. In total, this classification treats an estimated 11 916 species in 337 genera, 51 families, 14 orders, and two classes. This classification is not intended as the final word on lycophyte and fern taxonomy, but rather a summary statement of current hypotheses, derived from the best available data and shaped by those most familiar with the plants in question. We hope that it will serve as a resource for those wanting references to the recent literature on pteridophyte phylogeny and classification, a framework for guiding future investigations, and a stimulus to further discourse

    Revista Temas Agrarios Volumen 26; Suplemento 1 de 2021

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    1st International and 2nd National Symposium of Agronomic Sciences: The rebirth of the scientific discussion space for the Colombian Agro.1 Simposio Intenacional y 2 Nacional de Ciencias Agronómicas: El renacer del espacio de discusión científica para el Agro colombiano
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