Whitehead, CD Projekt RED e desenvolvimento de jogos: entrevista com Marcin Blacha

Interview with Marcin Blacha, game designer and Narrative Director of CD Projekt RED game studio about the relationship between academic studies and game development. Blacha addresses the approach of Whitehead's Philosophy and game design, issues concerning the singularities of games developed outside the anglophone world.Entrevista com Marcin Blacha, designer de jogos e Diretor de Narrativa do estúdio CD Projekt RED sobre as conexões entre os estudos acadêmicos e o desenvolvimento de jogos. Blacha aborda a aproximação da Filosofia de Whitehead e o design de jogos, assim como temas referentes as singularidades dos jogos desenvolvidos fora do eixo anglófono

O CONCEITO DE “PARTICIPAÇÃO ATIVA” NA TEOLOGIA LITÚRGICA DE JOSEPH RATZINGER

O termo participação do latim participatio.onis, significa “ação ou efeito de participar”, fazer parte de alguma coisa. Em liturgia significa tomar parte na obra de salvação e da glória de Deus por meio de Nosso Senhor Jesus Cristo. Depois do Concílio Vaticano II, com a constituição litúrgica Sacrosantum Concilium, o termo participação ativa em relação a liturgia foi estudado e, de muitas maneiras, foi interpretado na Igreja, mas tal termo ainda não é bem compreendido por boa parte dos fiéis membros da mesma. A participação ativa não consiste movimentar-se na liturgia ou mesmo só exercer nela algum ministério específico. Para aprofundar o verdadeiro sentido da expressão e para remetê-la ao próprio Vaticano II, escolheu-se a teologia litúrgica de J. Ratzinger como expressão adequada e correta da perspectiva que subjaz a reforma litúrgica conciliar. Assim, o intérprete da actuosa participatio esperada pelo Concílio aqui é Ratzinger, pois em seu pensamento a participação na liturgia remete à ação externa, sim, e não só aos sentidos, mas vai além

OCURRENCIA DE HETERAKIS GALLINARUM (SCHRANK, 1788) (NEMATODA: HETERAKIDAE) EN GALLUS GALLUS DOMESTICUS LINNAEUS, 1758 EN VITORIA, ESPIRITO SANTO, BRASIL

Heterakis Dujardin, 1845 es un nemátodo que parasita las aves y presenta distribución cosmopolita. En Brasil, se registran 14 especies que ocurren en diferentes especies domesticadas y silvestres. Entre las especies reportadas, Heterakis gallinarum (Schrank, 1788) representa una amenaza potencial para los criaderos comerciales ya que es un vector de Histomonas meleagridis Smith, 1895, protozoario Trichomonadida que causa histomoniasis en las aves, una infección grave que puede ser letal y causar pérdidas económicas catastróficas. El presente estudio regsitra la ocurrencia de H. gallinarum en el ciego de pollos de corral (Gallus gallus domesticus Linnaeus, 1758) vendidos en un gran centro comercial de Vitoria, Espirito Santo, Brasil. En este estudio se describen e ilustran los tres ejemplares machos y tres hembras encontrados

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis

Background: Carbapenem-resistant Gram-negative bacteria are recognized as a cause of difficult-to-treat infections associated with high mortality. Objectives: To perform a systematic review of currently available data on distribution, characteristics and outcome associated with carbapenem-resistant bloodstream infections in adult neutropenic patients. Methods: Included studies were identified through Medline, Embase and Cochrane databases between January 1995 and April 2016. Random effect meta-analysis was used to quantify the association between carbapenem resistance and mortality and between carbapenem exposure and resistance. Results: A total of 30 studies from 21 countries were included. Overall carbapenem resistance varied from 2% to 53% (median 9%) among studies. Infections due to carbapenem-resistant Pseudomonas spp. were reported in 18 (60%) studies showing high median resistance rates (44% of all carbapenem-resistant Gram-negatives and 19% of Pseudomonas isolates). Resistance of Enterobacteriaceae was less commonly reported and bloodstream infections due to carbapenem-resistant Klebsiella spp. were mainly documented from endemic areas (Greece, Italy, Israel). Carbapenem resistance in Acinetobacter spp. was reported in 9 (30%) studies (median resistance 58% of Acinetobacter isolates). Mortality rates ranged from 33% to 71% (median 50%) in patients with carbapenem-resistant infections. Carbapenemresistance appeared to correlate with mortality (OR 4.89, 95% CI 3.30-7.26) and previous exposure to carbapenems (OR 4.63, 95% CI 3.08-6.96). Conclusions: Carbapenem resistance represents a threat to neutropenic patients. In this group, resistance is likely promoted by previous carbapenem use and leads to high mortality rates. The knowledge of resistance patterns is crucial and can direct clinicians in the use of alternatives to carbapenem-based regimens

Proceedings of Abstracts Engineering and Computer Science Research Conference 2019

© 2019 The Author(s). This is an open-access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For further details please see https://creativecommons.org/licenses/by/4.0/. Note: Keynote: Fluorescence visualisation to evaluate effectiveness of personal protective equipment for infection control is © 2019 Crown copyright and so is licensed under the Open Government Licence v3.0. Under this licence users are permitted to copy, publish, distribute and transmit the Information; adapt the Information; exploit the Information commercially and non-commercially for example, by combining it with other Information, or by including it in your own product or application. Where you do any of the above you must acknowledge the source of the Information in your product or application by including or linking to any attribution statement specified by the Information Provider(s) and, where possible, provide a link to this licence: http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/This book is the record of abstracts submitted and accepted for presentation at the Inaugural Engineering and Computer Science Research Conference held 17th April 2019 at the University of Hertfordshire, Hatfield, UK. This conference is a local event aiming at bringing together the research students, staff and eminent external guests to celebrate Engineering and Computer Science Research at the University of Hertfordshire. The ECS Research Conference aims to showcase the broad landscape of research taking place in the School of Engineering and Computer Science. The 2019 conference was articulated around three topical cross-disciplinary themes: Make and Preserve the Future; Connect the People and Cities; and Protect and Care

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected

Sequential morphological characteristics of murine fetal liver hematopoietic microenvironment in Swiss Webster mice

Embryonic hematopoiesis occurs via dynamic development with cells migrating into various organs. Fetal liver is the main hematopoietic organ responsible for hematopoietic cell expansion during embryologic development. We describe the morphological sequential characteristics of murine fetal liver niches that favor the settlement and migration of hematopoietic cells from 12 days post-coitum (dpc) to 0 day post-partum. Liver sections were stained with hematoxylin and eosin, Lennert’s Giemsa, Sirius Red pH 10.2, Gomori’s Reticulin, and Periodic Acid Schiff/Alcian Blue pH 1.0 and pH 2.5 and were analyzed by bright-field microscopy. Indirect imunohistochemistry for fibronectin, matrix metalloproteinase-1 (MMP-1), and MMP-9 and histochemistry for naphthol AS-D chloroacetate esterase (NCAE) were analyzed by confocal microscopy. The results showed that fibronectin was related to the promotion of hepatocyte and trabecular differentiation; reticular fibers did not appear to participate in fetal hematopoiesis but contributed to the physical support of the liver after 18 dpc. During the immature phase, hepatocytes acted as the fundamental stroma for the erythroid lineage. The appearance of myeloid cells in the liver was related to perivascular and subcapsular collagen, and NCAE preceded MMP-1 expression in neutrophils, an occurrence that appeared to contribute to their liver evasion. Thus, the murine fetal liver during ontogenesis shows two different phases: one immature and mainly endodermic (<14 dpc) and the other more developed (endodermic-mesenchymal; >15 dpc) with the maturation of hepatocytes, a better definition of trabecular pattern, and an increase in the connective tissue in the capsule, portal spaces, and liver parenchyma. The decrease of hepatic hematopoiesis (migration) coincides with hepatic maturation