14 research outputs found
Statistical methods for the detection of major genes in farm animal populations
- Author
- Publication venue
- The University of Edinburgh
- Publication date
- 01/01/1990
- Field of study
Recommended from our members
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
- Author
- Abbass Hakam
- Adhikari Neill
- Affleck Julia
- Agno Sathianathan Ronan
- Ahmad Norfaizan
- Ahmed Iram
- Ainscough Kate
- Al Qasim Eman
- Al Swaidan Lolowa
- Al-Bassam Wisam
- Al-Beidh Farah
- Al-Beidh Farah
- Albert Martin
- Alegria Ana
- Alexander Brian
- Alexander Peter
- Allan Angela
- Allan Elizabeth
- Allen Louise
- Allibone Suzanne
- Amaro dos Santos Catorze Teodoro
- Anderson Tom
- Andric Zdravko
- Angus Derek
- Angus Derek C
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Annane Djillali
- Anstey Matthew
- Antcliffe David
- Aparicio Christelle
- Appelt Peter
- Arabi Yaseen
- Arabi Yaseen
- Arbane Gill
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arishi Hatim
- Arnold Donald
- Asghar Adeeba
- Ashelford Angela
- Attwood Ben
- Austin Karen
- Aysel Florescu Simin
- Azaiz Amine
- Babel JakĆĄa
- Babio-Galan Maite
- Badie Julio
- Bagshaw Sean
- Baillie Kenneth
- Baker Evelyn
- Bakthavatsalam Dhanalakshmi
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbazza Leanne
- Barber Russell
- Barge Deborah
- Barnes Nicky
- BarĆĄiÄ Bruno
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bates Michelle
- Bauchmuller Kris
- Bean Sarah
- Beane Abigail
- Beane Abigail
- Beasley Richard
- Begin Phillipe
- Bellemare David
- Benettaib Fatna
- Benzekri Dalila
- Berdaguer Fernando Daniel
- Bergin Colin
- Berry Lindsay
- Berry Lindsay
- Berry Scott
- Berry Scott
- Bhimani Zahra
- Bhimani Zahra
- Bihari Shailesh
- Bihari Shilesh
- Binnie Alexandra
- Bion Julian
- Biradar Vishwanath
- Birch Janine
- Birch Jenny
- Birchall Katie
- Birkinshaw Isobel
- Black Ethel
- Bloos Frank
- Board Jasmin
- Bone Allsion
- Bonner Stephen
- Bonten Marc
- Bonten Marc
- Borgatta Barbara
- Borrill Zoe
- Bosch Ziekenhuis Jeroen
- Boschert Catherine
- Bossard Isabelle
- Boumahni Dounia
- Bourgoin Charlotte
- Bourne Michelle
- Bourne Richard
- Bouwman Wietske
- Bowler Helen
- Boyd Craig
- Bracke Stephanie
- Bradbury Charlotte
- Bradbury Charlotte
- Bradley-Potts Joanne
- Brailsford Jane
- Brain Matthew
- Brant Emily
- Breen Patrick
- Brett Stephen
- Brewer Chris
- Brickell Kathy
- Brightling Chris
- Brillinger Nicole
- Brimfield Lutece
- Brinkerhoff Gail
- Brochard Laurent
- Brohi Farooq
- Browne Troy
- Brunkhorst Frank
- Brunkhorst Frank
- Budd Joanna
- Buehner Ulrike
- Buhr Heidi
- Bullman Laetitia
- Burns Karen
- Burt Karen
- Buscher Hergen
- Butler Amelia
- Butler M
- Buxton Meredith
- Buxton Meredith
- Buzgau Adrian
- Byrne Deborah
- Byrne Kathleen
- BĂ©lteczki JĂĄnos
- Cabreros Leilani
- Calfee Carolyn
- Callender Owen
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- Campbell Hilary
- Campbell Lewis
- Camsooksai Julie
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- Carbonneau Elaine
- Carmona Flores Rosario
- Carr-Knott Lisa
- Carrier François Martin
- Carrier Marc
- Cartner Brittney
- Casey Ruth
- Casey Siobhan
- Castro Ferreira Ricardo Manuel
- Cate Heidi
- Cathcart Susanne
- Cavayas Alexandros
- Cawley Kathryn
- Cazzola Federica
- Centofanti John
- Chablani Manish
- Chamara Warnapura Loku
- Chan Carmen
- Chan Charles
- Chan Peter
- Charlewood Richard
- Charron Cyril
- Chartier Delphine
- Chasse Michael
- Chassé Michaël
- Chen Yan
- Cheng Allen
- Cheng Allen C
- Cherian Shiney
- Cheung Winston
- Chhablani Manish
- Chudeau Nicolas
- Cirstea Emanuel
- Clarey Emma
- Claridge Helen
- Clark Michele
- Clark Sarah
- Claxton Andrew
- Clermont Giles
- Cloutier Ăve
- Coburn Susan
- Codreanu Daniel
- Coghlan Phoebe
- Cole Jade
- Coles Holly
- Coles Jennifer
- Colin Gwenhael
- Collier Dawn
- Collins Daniel
- Collins Emma
- Collins Joanne
- Connor Jason
- Cooke Jill
- Cooper Jamie
- Cooper Melanie
- Cornell Sarah
- Cort Jon
- Courtin Laura
- Cowdrey Keri-Anne
- Cowley Nicholas
- Cowton Amanda
- Coyne Mark
- Craner Michelle
- Craven Thomas
- Creagh-Brown Ben
- Crisp Nikki
- Croft Maria
- Cusack Rebecca
- Cutler Sean
- Cviljevic Sabina
- CĂĄrcel FernĂĄndez Sheila
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- Daly Zoe
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- Dark Paul
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- Dasgin Joanne
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- Davies Michelle
- Dawda Ashlish
- Day Christopher
- De Beaux Fiona
- De Bus Liesbet
- de Courcy-Golder Kim
- de Jager P
- de Jong Menno
- De Jong Menno
- de Jonge E
- de la Fuente Martos Carmen
- de Lima Pereira Tiago Nuno Alfaro
- de Man Angelique
- De Waele Jan
- Dearden Joy
- Dechert William
- Deelchand Vashish
- Dela Rosa Arnold
- Dell Amanda
- Demetriou Carrie
- Depante Maria Theresa
- Depuydt Pieter
- Dequin PierreFrançois
- Derde Lennie
- Derde Lennie
- Detry Michelle
- Detry Michelle
- Deye Nicolas
- Digby Stephen
- Distler Michael
- Doble Patricia
- Donnelly Adrian
- Donnison Phil
- Doran Peter
- Dragija Lidija
- Driscoll Alana
- Drummond Andrew
- Duan Erick
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- Duke Graeme
- Duncan Tracey
- Duplaix Mathilde
- Dushianthan Ahilanandan
- Dyas Sarah
- DâAragon FrĂ©dĂ©rick
- DâSouza Ramsy
- Effelaar Evelien
- Elhassan Munzir
- Elin Hall Rebecca
- Ellis Christine
- Elmahi Einas
- Elsefi Tarek
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- Estcourt Lise
- Estcourt Lise
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- Everitt Robert
- Evers Mirjam
- Farahi Neda
- Fartoukh Muriel
- Faulkner Beverley
- Faulkner Maria
- Fazekas Ăgnes
- Felton Tim
- Ferguson Niall
- Ferguson Susan
- Fergusson Dean
- FernĂĄndez de Pinedo Artaraz Ziortza
- Ferrier Janet
- Fierens Jan
- Finn André
- Finn Stephanie
- Fischer Roy
- Fitzgerald Mark
- Fitzgerald Mark
- Fletcher Simon
- Flint Neil
- Forbes Andrew
- Forbes Loretta
- Forton Daniel
- Fortune Louise
- Fottrell-Gould Deirdre
- Fowler Rob
- Fowler Robert
- Fox Claire
- Francia Federica
- Francoeur Charles
- Frey Anna
- Friedrich Hinrichs Carl
- Frohlich Stephen
- Fysh Ed
- Gallagher Linda Jude
- Ganguly Saibal
- Ganpat Radhika
- Garcia Rebecca
- Gardiner-Hill Caroline
- Garrard Hywel
- Garrard William
- Gates Simon
- Gattas David
- Gellamucho Minerva
- Gendall Emma
- Genetu Roman Mary
- Geng Wenli
- Geri Guillaume
- Ghamraoui Ali
- Ghosh Alison
- Gibson Charly
- Girard Timothy
- Girijadevi Dinu
- Gledhill Lisa
- Godement Mathieu
- Golden David
- Goligher Ewan
- Gomm Linda
- Goodson Jennifer
- Goodwin Jayne
- Goossens Herman
- Goossens Herman
- Gopal Shameer
- Gopinath Amitha
- Gordon Anthony
- Gordon Anthony C
- Gordon Elizabeth
- Gosbell Iain
- Gould Richard
- Grecu Irina
- Green Cameron
- Green Cameron
- Gregory Jane
- Gresha Rebecca
- Grimmer Lisa
- Grimwade Kate
- Guilder E
- Guitton Christophe
- Hacking Danielle
- Hadebe Bernard
- Hagel Stefan
- Haidar Ghady
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- Hall Kathryn
- Hamilton David Oliver
- Hamilton-Davies Colin
- Hamlyn Vincent
- Hammond Naomi
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- Haniffa Rashan
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- Harland Cain
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- Harward Meg
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- Heinonen Jonna
- Heming Nicholas
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- Henderson Steven
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- Heritier Stephane
- Hickey Naomi
- Higgins Alisa M
- Higgins Lisa
- Hill Helen
- Hills Thomas
- Hills Tom
- Hird Clare
- Hodgson Carol
- Hoff Uwe
- Hoiting Oscar
- Holland Nicky
- Hollos Laszlo
- Homes Jennifer
- Hope David
- Hopkins Phil
- Hormis Anil
- Horton Michelle
- Horton Sarah
- Horvat Christopher
- Horvat Christopher
- Howcroft Clare
- Howle Ryan
- Huang David
- Huckle Abby
- Hughes Emma
- Hugill Keith
- Hullegie Sebastiaan
- Hullegie Sebastiaan J
- Hulley Amanda
- Hulme Jonathan
- Hunt Beverley
- Hunter Stephanie
- Hutter Joanne
- Hutton Paula
- Innes Richard
- Ireland Jane
- Isgro Graziella
- Ivatt Helen
- Jackson Matthew
- Jackson Shane
- Jackson Susan
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- Jacquier Sophie
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- Jarczak Dominik
- Jeblaoui Asma
- Jeffrey Helen
- Jenkins Sarah
- Jha Rajeev
- Jhanji Shaman
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- Johnson David
- Johnson Rebekah
- Johnston Paul
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- Jones Jo
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- José Nuno
- Juhaz Vera
- Kalchthaler Kyle
- Kalogirou Michael
- Kamel Toufik
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- Karlikowski Michal
- Karlsson Sari
- Kasipandian Vidya
- Kayani Abdul
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- Keen Alexandra
- Keenan Samantha
- Keet Owen
- Kell Kay
- Kelly Martin
- Kelsall Olivia
- Kernan Maeve
- Kersiake Ian
- Khalid Imrana
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- Kinney Fiona
- Kirkby Amy
- Klinikum Neukölln Vivantes
- Kluge Stefan
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- Krishnamurthy Vinodh
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- Kruger Peter
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- Kumar Anand
- Kumar Nikhil
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- Kyeremeh Lynsey
- Labbe Vincent
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- Lamontagne Francois
- Lamontagne François
- Landais Mickaël
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- Lankester Liana
- Laver Russell
- Lawler Patrick
- Lawler Patrick R
- Lawless Patrick
- Lazaro Juan Martin
- Leaver Susannah
- Leblond Julie
- Lee Kelvin
- Lee Stephanie
- Leparco CĂ©cile
- Lesona Eden
- Leszkoven JĂĄnos
- Lewis Roger
- Lewis Roger J
- Lewis Sarah
- LeĂłn LĂłpez Rafael
- Limb James
- Linstrum Kelsey
- Linstrum Kelsey
- Litton Ed
- Litton Edward
- Litton Edward
- Lomme Kaatje
- London Emily
- Lorenzi Elizabeth
- Lorenzi Elizabeth
- Lother Sylvain
- Lowe Benjamin
- Lowrey Julie
- Luis David
- Luk Tracy
- LâHotellier Sylvie
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- Mackay Euan
- MacLennan Sheila
- Maguire Teena
- Magyar IstvĂĄn
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- Mandadapu Vineela
- Mangindaan Yara
- Maquigneau Natacham
- Marabi Yaseen
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- Marin-Corral Judith
- Markgraf Rene
- Marroquin Oscar
- Marshall John
- Marshall John
- Marshall Nicola
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- Marten Nicole
- Martin Jane
- Martin Timothy
- Martynoga Robert
- Maselli Astrid
- Masse Marie-Helene
- Mateo LĂłpez Maria Isabel
- Matsa Ramprasad
- Mattocks Lehentha
- Maxime Virginie
- Mc Goldrick Clare
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- McArthur Colin
- McArthur Colin
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- McAuley Daniel
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- Montgomery Stephanie
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- Moviat M
- Mullan Dee
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- Oczkowski Simon
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- Orath Prabakaran Rajalakshmi
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- OâDywer Michael
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- OâKane SinĂ©ad
- OâMalley Laura
- OâNeill Aisling
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- Panwar Rakshit
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- Patel Kamal
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- Paterson David
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- Pereira Rita
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- PettilÀ Leena
- Phalod Gunjan
- Philbin Jennifer
- Phillips Barbara
- Phull Mandeep-Kaur
- Pillai Suresh
- Pinder Meredith
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- Pletz Mathias
- Pletz Mathias
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- Pogreban Tatiana
- Pogson David
- Polderman F
- Polgarova Petra
- Pomeroy Fiona
- Porteous Rebecca
- Porter David
- Potter Alison
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- Powell Elizabeth
- Powell Matthew
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- Pugh Richard
- Pulletz Mark
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- Purohit Dharam
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- Puthucheary Zudin
- Puxty Kathryn
- Quayle Rachael
- Quinn Kevin
- Qureshi Hafiz
- Rad Laura
- Rademaker Emma
- Rae Nicola
- Raithatha Ajay
- Ramali Mohamed
- Ramanan Mahesh
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- Randell Georgina
- Rauniyar Rashmi
- Raymakers Kik
- Reddy Amie
- Reddy Harsha
- Rees Tabitha
- Reeve Brenda
- Regli Adrian
- Reill Lorenz
- Rengers Els
- Reschreiter Henrik
- Reynolds Claire
- Reynolds John
- Rhodes Jonathan
- Richards-Belle Alvin
- Ricketts Daniel
- Rietveld Ilse
- RistimÀki Sanna
- Ritzema Carter Jay
- Robert Alain
- Roberts David
- Robertson Yvonne
- Robinson Matt
- Robinson Philip
- Rochwerg Bram
- Rodden Natalie
- Rodriguez Fernandez Jorge
- Roedl Kevin
- Rohde Gernot
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- Rook Clare
- Rooney Kevin
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- Selvamoni Selvin
- Senya Ho Jan
- Seppelt Ian
- Serri Karim
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- Seymour Christopher
- Seymour Christopher
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- Shakih Arif
- Shankar-Hari Manu
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- Shaw Joanne
- Shearer Audrey
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- Shehabi Yahya
- Shovelton Charmaine
- Shrestha Tapaswi
- Shyamsundar Murali
- Siami Shidasp
- Silversides Jon
- Sim Malcolm
- Simmonds Catherine
- Simons Koen
- Simpson Joanne
- Simpson Scott
- Singh Vanessa
- Singleton Jo
- Sinha Pratik
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- Small Charlotte
- Smallwood Andrew
- Smee Joanna
- Smith Joanne
- Smith John
- Smith Judith
- Smith Julie
- Smith Kirsy
- Smith Margaret
- Smith Roger
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- Smith Tim
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- Spittle Nick
- Spivey Michael
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- Stanworth Simon
- Sterba Martin
- Stevenson Hannah
- Stewart Richard
- Strzelecka Anna
- Sundara Raman Ajay
- Sundaran Dhinesh
- Sutherland Helen
- Sutterlin Laetitia
- Sutu Mihaela
- Sweet Katie
- Szakmany Tamas
- Szigligeti GĂĄbor
- SzĆke ViktĂłria
- Tallott Mandy
- Tatham Kate Colette
- Templeton Maie
- Thomas Amy
- Thomas Helen
- Thomas Matt
- Thomas Matthew
- Thompson Taylor
- Thomson Nicola
- Thrush Jessica
- Tilney Emma
- Tinmouth Alan
- Tong Steve
- Tooley Joe
- Touma Omar
- Trapani Tony
- Trask Kara
- Triulzi Darrell
- Trodd Dawn
- Tsang Jennifer
- Tully Redmond
- Turgeon Alexis
- Turki Salah
- Turner Anne
- Turner Anne
- Turner-Bone Ian
- Turns Margaret
- Uddin Ruzena
- Udy Andrew
- Uyeki Tim
- Vaara Suvi
- Vahtera Annukka
- Vamplew Luke
- van Bentum Puijk Wilma
- van Bentum-Puijk Wilma
- van Bentum-Puijk Wilma
- van Beurden Marloes
- van de Veerdonk Frank
- van de Veerdonk Frank
- Van Der Heyden Kym
- van der Poll Tom
- vanât Hoff Willian
- Vates Jennifer
- Vautier Sarah
- Vazquez-Grande Gloria
- Venkatesh Bala
- Venkatesh Balasubramanian
- Venz Ellen
- Verlander Mark
- Verrier Nathalie
- Victor Saji
- Vieillard-Baron Antoine
- Voicu Sebastian
- Vowell Emma
- Vujaklija BrajkoviÄ Ana
- Vuylsteke Alain
- Wagh Atul
- Walden Andrew
- Walker Rachel
- Walsh Joanne
- Walsh Tim
- Walsham James
- Ward Kathryn
- Warnock Majella
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watters Malcolm
- Waugh Victoria
- Webb Steve
- Webb Steven A
- Wedd Steve
- Weismann Dirk
- Weissman Alexandra
- Wells Colin
- Welters Ingeborg
- Wetherill Bill
- Whelan Ruth
- Whileman Amanda
- Whitbread Jennifer
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Wibrow Bradley
- Wigbers J
- Wilby Elizabeth
- Wild Laura
- Wild Laura
- Wilding Laura
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Erin
- Williams Hannah
- Williams Karen
- Williams Patricia
- Williams Patricia
- Williams Penny
- Williams Tony
- Williams Virginie
- Williamson Dawn
- Williamson James
- Wilson Karen
- Wilson Maggie
- Wiseman Sophie
- Wong Helen
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Writing Committee for the REMAP-CAP Investigators
- Xavier Kugan
- Xia Le Tai Charlotte
- Yarad Elizabeth
- Yates David
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Yusuff Hakeem
- Zaharia Miahela Florentina
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zarychanski Ryan
- Zhao Xiao Bei
- Zinzoni Vanessa
- Zitter Letizia
- Äimoti Renata
- Publication venue
- JAMA: Journal of the American Medical Association
- Publication date
- 06/10/2020
- Field of study
Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (nâ=â143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (nâ=â152), or no hydrocortisone (nâ=â108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (nâ=â137), shock-dependent (nâ=â146), and no (nâ=â101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
- Author
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Akil Huda
- Albani Diego
- Albus Margot
- Alda Martin
- Alexander Madeline
- Alliey-Rodriguez Ney
- Als Thomas D
- Amin Farooq
- Andreassen Ole A
- Anjorin Adebayo
- Arranz Maria J
- Awasthi Swapnil
- Bacanu Silviu A
- Badner Judith A
- Baekvad-Hansen Marie
- Bakker Steven
- Band Gavin
- Barchas Jack D
- Barroso Ines
- Bass Nicholas
- Bauer Michael
- Baune Bernhard T
- Begemann Martin
- Bellenguez Celine
- Bellivier Frank
- Bender Stephan
- Bene Judit
- Bergen Sarah E
- Berrettini Wade H
- Bevilacqua Elizabeth
- Biernacka Joanna M
- Bigdeli Tim B
- Black Donald W
- Blackburn Hannah
- Blackwell Jenefer M
- Blackwood Douglas HR
- Boehnke Michael
- Boks Marco
- Boocock James
- Borglum Anders D
- Bramon Elvira
- Breen Gerome
- Brown Matthew A
- Bruggeman Richard
- Buccola Nancy G
- Buckner Randy L
- Budde Monika
- Bulik-Sullivan Brendan
- Bumpstead Suzannah J
- Bunney William
- Burmeister Margit
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William
- Cahn Wiepke
- Cai Guiqing
- Cairns Murray J
- Campion Dominique
- Cantor Rita M
- Carr Vaughan J
- Carrera Noa
- Casas Juan P
- Casas Miquel
- Case-Control Wellcome Trust
- Catts Stanley V
- Cervantes Pablo
- Chambert Kimberley D
- Chan Raymond CK
- Charney Alexander W
- Chen Eric YH
- Chen Ronald YL
- Cheng Wei
- Cheung Eric FC
- Chong Siow Ann
- Cichon Sven
- Clarke Toni-Kim
- Cloninger C Robert
- Cohen David
- Cohen Nadine
- Coleman Jonathan RI
- Collier David A
- Consortium Psychiat Genomics
- Consortium Psychiat Genomics
- Cormican Paul
- Corvin Aiden
- Coryell William
- Craddock Nicholas
- Craig David W
- Crespo-Facorro Benedicto
- Crowley James J
- Cruceanu Cristiana
- Cuellar-Barboza Alfredo B
- Curtis David
- Czerski Piotr M
- Dale Anders M
- Daly Mark J
- Dannlowski Udo
- Darvasi Ariel
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- de Leeuw Christiaan A
- Degenhardt Franziska
- Del Favero Jurgen
- DeLisi Lynn E
- Deloukas Panos
- Demontis Ditte
- DePaulo J Raymond
- Di Florio Arianna
- di Forti Marta
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Dobbyn Amanda L
- Domenici Enrico
- Donnelly Peter
- Donohoe Gary
- Drapeau Elodie
- Dronov Serge
- Duan Jubao
- Dudbridge Frank
- Duncanson Audrey
- Edenberg Howard
- Edkins Sarah
- Ehrenreich Hannelore
- Eichhammer Peter
- Elvsashagen Torbjorn
- Eriksson Johan
- Escott-Price Valentina
- Esko Tonu
- Essioux Laurent
- Etain Bruno
- Fan Chun Chieh
- Fanous Ayman H
- Farh Kai-How
- Farrell Martilias S
- Flickinger Matthew
- Foroud Tatiana M
- Forstner Andreas J
- Forty Liz
- Frank Josef
- Franke Lude
- Fraser Christine
- Freedman Robert
- Freeman Colin
- Freimer Nelson B
- Friedman Joseph I
- Fromer Menachem
- Frye Mark A
- Fullerton Janice M
- Gade Katrin
- Garnham Julie
- Gaspar Helena A
- Gejman Pablo V
- Genovese Giulio
- Georgieva Lyudmila
- Gershon Elliot S
- Giambartolomei Claudia
- Giannoulatou Eleni
- Giegling Ina
- Gill Michael
- Gillman Matthew
- Giusti-Rodriguez Paola
- Godard Stephanie
- Goes Fernando
- Goldstein Jacqueline I
- Gopal Srihari
- Gordon Scott D
- Gordon-Smith Katherine
- Gratten Jacob
- Gray Emma
- Green Elaine K
- Green Melissa J
- Greenwood Tiffany A
- Grigoroiu-Serbanescu Maria
- Grove Jakob
- Guan Weihua
- Gurling Hugh
- Gwilliam Rhian
- Hall Jeremy
- Hall Mei-Hua
- Hammer Christian
- Hammond Naomi
- Hamshere Marian L
- Hansen Christine Soholm
- Hansen Mark
- Hansen Thomas
- Haroutunian Vahram
- Hartmann Annette M
- Hauser Joanna
- Hautzinger Martin
- Heilbronner Urs
- Hellenthal Garrett
- Henskens Frans A
- Herms Stefan
- Hipolito Maria
- Hirschhorn Joel N
- Hoffmann Per
- Hollegaard Mads V
- Holmans Peter A
- Hougaard David M
- Huang Hailiang
- Huckins Laura
- Hultman Christina M
- Hunt Sarah E
- Ikeda Masashi
- Inter Psychosis Endophenotypes
- Iwata Nakao
- Iyegbe Conrad
- Jablensky Assen V
- Jamain Stephane
- Jankowski Janusz
- Jayakumar Alagurevathi
- Joa Inge
- Jones Ian
- Jones Lisa A
- Jonsson Erik G
- Jr Belliveau Richard A
- Jr Macek Milan
- Julia Antonio
- Jureus Anders
- Kahler Anna K
- Kahn Rene S
- Kalaydjieva Luba
- Kalman Janos L
- Kandaswamy Radhika
- Karachanak-Yankova Sena
- Karjalainen Juha
- Karlsson Robert
- Kavanagh David
- Keller Matthew C
- Kelly Brian J
- Kelsoe John
- Kendler Kenneth S
- Kennedy James L
- Keong Jimmy Lee Chee
- Khrunin Andrey
- Kim Yunjung
- Kirov George
- Kittel-Schneider Sarah
- Klovins Janis
- Knight Jo
- Knott Sarah V
- Knowles James A
- Kogevinas Manolis
- Konte Bettina
- Kravariti Eugenia
- Kucinskas Vaidutis
- Kucinskiene Zita Ausrele
- Kupka Ralph
- Kuzelova-Ptackova Hana
- Landen Mikael
- Langford Cordelia
- Laurent Claudine
- Lawrence Jacob
- Lawrie Stephen
- Lawson William B
- Leber Markus
- Leboyer Marion
- Lee Phil H
- Lee S Hong
- Legge Sophie E
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F
- Levy Shawn E
- Lewis Cathryn M
- Li Jun Z
- Li Miaoxin
- Li Qingqin S
- Li Tao
- Liang Kung-Yee
- Liddle Jennifer
- Lieberman Jeffrey
- Limborska Svetlana
- Lin Kuang
- Linszen Don H
- Lissowska Jolanta
- Liu Chunyu
- Liu Jianjun
- Lonnqvist Jouko
- Loohuis Loes M Olde
- Loughland Carmel M
- Lubinski Jan
- Lucae Susanne
- MacIntyre Donald J
- Magnusson Patrik KE
- Maher Brion S
- Mahon Pamela B
- Maier Wolfgang
- Malhotra Anil K
- Mallet Jacques
- Malt Ulrik F
- Markus Hugh S
- Marsal Sara
- Martin Nicholas G
- Mata Ignacio
- Mathew Christopher G
- Mattheisen Manuel
- Mattingsdal Morten
- Mayoral Fermin
- McCann Owen T
- McCarley Robert W
- McCarroll Steven A
- McCarthy Mark I
- McDonald Colm
- McElroy Susan L
- McGuffin Peter
- McInnis Melvin G
- McIntosh Andrew M
- Mckay James D
- McMahon Francis J
- McQuillin Andrew
- Medeiros Helena
- Medland Sarah E
- Meier Sandra
- Meijer Carin J
- Melegh Bela
- Melle Ingrid
- Meng Fan
- Mesholam-Gately Raquelle I
- Metspalu Andres
- Michie Patricia T
- Milani Lili
- Milanova Vihra
- Mitch-Ell Philip B
- Mokrab Younes
- Montgomery Grant W
- Moran Jennifer L
- Morken Gunnar
- Morris Derek W
- Mors Ole
- Mortensen Preben B
- Mowry Bryan J
- Muhleisen Thomas W
- Muller-Myhsok Bertram
- Mullins Niamh
- Murphy Kieran C
- Murray Robin M
- Myers Richard M
- Myin-Germeys Inez
- Neale Benjamin M
- Nelis Mari
- Nenadic Igor
- Nertney Deborah A
- Nestadt Gerald
- Nicodemus Kristin K
- Nievergelt Caroline M
- Nikitina-Zake Liene
- Nimgaonkar Vishwajit
- Nisenbaum Laura
- Nordentoft Merete
- Nordin Annelie
- Nothen Markus M
- Nurnberger John I
- Nwulia Evaristus A
- O'Callaghan Eadbhard
- O'Donovan Claire
- O'Donovan Michael C
- O'Dushlaine Colm
- O'Neill F Anthony
- Oedegaard Ketil J
- Oh Sang-Yun
- Olincy Ann
- Olsen Line
- Ophoff Roel A
- Ori Anil PS
- Oruc Lilijana
- Owen Michael J
- Paciga Sara A
- Palmer Colin NA
- Palotie Aarno
- Pantelis Christos
- Papadimitriou George N
- Papiol Sergi
- Parkhomenko Elena
- Parra Jose Guzman
- Pato Carlos
- Pato Michele T
- Paunio Tiina
- Pavlides Jennifer M Whitehead
- Pearson Richard
- Pedersen Carsten Bocker
- Pedersen Marianne Giortz
- Perkins Diana O
- Perlis Roy H
- Perry Amy
- Pers Tune H
- Petryshen Tracey L
- Pfennig Andrea
- Picchioni Marco
- Pietilainen Olli
- Pimm Jonathan
- Pirinen Matti
- Plomin Robert
- Pocklington Andrew J
- Posthuma Danielle
- Potash James B
- Potter Simon C
- Powell John
- Price Alkes
- Pulver Ann E
- Purcell Shaun M
- Quested Digby
- Ramos-Quiroga Josep Antoni
- Rasmussen Henrik B
- Rautanen Anna
- Ravindrarajah Radhi
- Regeer Eline J
- Reichenberg Abraham
- Reif Andreas
- Reimers Mark A
- Ribases Marta
- Rice John P
- Richards Alexander L
- Ricketts Michelle
- Rietschel Marcella
- Riley Brien P
- Ripke Stephan
- Rivas Fabio
- Rivera Margarita
- Roffman Joshua L
- Rouleau Guy A
- Roussos Panos
- Ruderfer Douglas M
- Rujescu Dan
- Salomaa Veikko
- Sanchez-Mora Cristina
- Sanders Alan R
- Sawcer Stephen J
- Schall Ulrich
- Schatzberg Alan F
- Scheftner William A
- Schofield Peter R
- Schork Nicholas J
- Schulze Thomas G
- Schwab Sibylle G
- Scolnick Edward M
- Scott Laura J
- Scott Rodney J
- Seidman Larry J
- Serretti Alessandro
- Sham Pak C
- Shehktman Tatyana
- Shi Jianxin
- Shilling Paul D
- Sigurdsson Engilbert
- Silverman Jeremy M
- Sim Kang
- Sklar Pamela
- Slaney Claire
- Slominsky Petr
- Smeland Olav B
- Smoller Jordan W
- So Hon-Cheong
- Sobell Janet L
- Soderman Erik
- Spencer Chris CA
- Spijker Anne T
- St Clair David
- Stahl Eli A
- Stefansson Hreinn
- Stefansson Kari
- Steinberg Stacy
- Stogmann Elisabeth
- Stordal Eystein
- Strange Amy
- Straub Richard E
- Strauss John S
- Streit Fabian
- Strengman Eric
- Strohmaier Jana
- Stroup T Scott
- Su Zhan
- Subramaniam Mythily
- Sullivan Patrick F
- Suvisaari Jaana
- Svrakic Dragan M
- Szatkiewicz Jin P
- Szelinger Szabolcs
- Tashakkori-Ghanbaria Avazeh
- Thirumalai Srinivas
- Thompson Robert C
- Thorgeirsson Thorgeir E
- Toncheva Draga
- Tooney Paul A
- Tosato Sarah
- Toulopoulou Timothea
- Trembath Richard C
- Treutlein Jens
- Trubetskoy Vassily
- Trubetskoy Vassily
- Turecki Gustavo
- Vaaler Arne E
- Van Os Jim
- Vedder Helmut
- Vieta Eduard
- Vincent John
- Visscher Peter M
- Viswanathan Ananth C
- Vukcevic Damjan
- Waddington John
- Waller Matthew
- Walsh Dermot
- Walshe Muriel
- Walters James TR
- Wang Dai
- Wang Qiang
- Wang Weiqing
- Wang Yunpeng
- Watson Stanley J
- Webb Brad-Ley T
- Weickert Cynthia Shannon
- Weickert Thomas W
- Weinberger Daniel R
- Weisbrod Matthias
- Weiser Mark
- Werge Thomas
- Weston Paul
- Whittaker Pamela
- Widaa Sara
- Wiersma Durk
- Wildenauer Dieter B
- Williams Nigel M
- Williams Stephanie
- Witt Stephanie H
- Wolen Aaron R
- Wong Emily HM
- Wood Nicholas W
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Xi Simon
- Xu Wei
- Young Allan H
- Zai Clement C
- Zandi Peter
- Zhang Peng
- Zheng Xuebin
- Zimprich Fritz
- Zollner Sebastian
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc
Genetic Overlap Between Alzheimerâs Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes
- Author
- Adebayo Anjorin
- Aiden Corvin
- Alan F Schatzberg
- Alessandro Serretti
- Alexander W Charney
- Alexey A. Shadrin
- Allan H Young
- Amanda L Dobbyn
- Amanda L Dobbyn
- Amy Perry
- Anders D BĂžrglum
- Anders D BĂžrglum
- Anders D BĂžrglum
- Anders JureĂŹus
- Anders M Dale
- Anders M Dale
- Anders M Dale
- Anders M Dale
- Anders M. Dale
- Anders M. Dale
- Anders M. Dale
- Andrea Pfennig
- Andreas J Forstner
- Andreas J Forstner
- Andreas J Forstner
- Andreas J Forstner
- Andreas J Forstner
- Andreas J Forstner
- Andreas Reif
- Andres Metspalu
- Andres Metspalu
- Andrew M McIntosh
- Andrew M McIntosh
- Andrew McQuillin
- Andrew McQuillin
- Anil P S Ori
- Anna C Koller
- Anna C Koller
- Anna Maaser
- Anna Maaser
- Anne T Spijker
- Annelie Nordin Adolfsson
- Aree Witoelar
- Aree Witoelar
- Arianna Di Florio
- Arianna Di Florio
- Arne E Vaaler
- Ashley Dumont
- Benjamin M Neale
- Benjamin M Neale
- Benjamin M Neale
- Bernhard T Baune
- Bertram MĂŒller-Myhsok
- Bertram MĂŒller-Myhsok
- Bertram MĂŒller-Myhsok
- Bruno Etain
- Bruno Etain
- Bruno Etain
- Bruno Etain
- Carlos Pato
- Carlos Pato
- Caroline M Nievergelt
- Caroline M Nievergelt
- Carsten BĂžcker Pedersen
- Carsten BĂžcker Pedersen
- Carsten BĂžcker Pedersen
- Catharina Lavebratt
- Cathryn M Lewis
- Cathryn M Lewis
- Cathryn M Lewis
- CeĂŹline S Reinbold
- CeĂŹline S Reinbold
- Christiaan A de Leeuw
- Christina M Hultman
- Christine Fraser
- Christine SĂžholm Hansen
- Christine SĂžholm Hansen
- Chun Chieh Fan
- Chunyu Liu
- Claire Churchhouse
- Claire Churchhouse
- Claire OâDonovan
- Claire Slaney
- Claudia Giambartolomei
- Cristiana Cruceanu
- Cristiana Cruceanu
- Cristina SaĂŹnchez-Mora
- Cristina SaĂŹnchez-Mora
- Cristina SaĂŹnchez-Mora
- Cynthia Shannon Weickert
- Cynthia Shannon Weickert
- Danfeng Chen
- Danielle Posthuma
- Danielle Posthuma
- David Curtis
- David Curtis
- David M Hougaard
- David M Hougaard
- David St Clair
- David W Craig
- Derek W Morris
- Derek W Morris
- Diane Gage
- Diego Albani
- Dominic Holland
- Dominic Holland
- Donald J MacIntyre
- Donald J MacIntyre
- Douglas H R Blackwood
- Douglas M Ruderfer
- Eduard Vieta
- Elaine K Green
- Eli A Stahl
- Eli A Stahl
- Eli A Stahl
- Eli A Stahl
- Eline J Regeer
- Elliot S Gershon
- Elliot S Gershon
- Engilbert Sigurdsson
- Erlend BĂžen
- Esben Agerbo
- Esben Agerbo
- Esben Agerbo
- Euijung Ryu
- Evaristus A Nwulia
- Eystein Stordal
- Eystein Stordal
- Fabian Streit
- Fabio Rivas
- Fan Meng
- Fan Meng
- Felecia Cerrato
- Fermin Mayoral
- Fernando Goes
- Francis J McMahon
- Frank Bellivier
- Frank Bellivier
- Frank Bellivier
- Frank Bellivier
- Franziska Degenhardt
- Franziska Degenhardt
- George Kirov
- Gerome Breen
- Gerome Breen
- Gerome Breen
- Grant W Montgomery
- Gunnar Morken
- Gunnar Morken
- Gustavo Turecki
- Guy A Rouleau
- Guy A Rouleau
- Helena Medeiros
- Helmut Vedder
- HeĂŹleĂŹna A Gaspar
- HeĂŹleĂŹna A Gaspar
- Hoang Nguyen
- Hoang Nguyen
- Howard J Edenberg
- Hreinn Stefansson
- Huda Akil
- Ian Jones
- Ingrid Agartz
- Ingrid Agartz
- Ingrid Agartz
- Ingrid Melle
- Ingrid Melle
- J Raymond DePaulo
- Jack D Barchas
- Jacob Lawrence
- Jakob Grove
- Jakob Grove
- Jakob Grove
- Jakob Grove
- James A Knowles
- James A Knowles
- James B Potash
- James Boocock
- James D McKay
- James L Kennedy
- James L Kennedy
- James L Kennedy
- James L Kennedy
- Jana Strohmaier
- Janet L Sobell
- Janice M Fullerton
- Janice M Fullerton
- Jaqueline Goldstein
- Jennifer M Whitehead Pavlides
- Jens Treutlein
- Jessica S Johnson
- Jessica S Johnson
- Joanna Hauser
- Joanna M Biernacka
- John B Vincent
- John I Nurnberger
- John Kelsoe
- John Kelsoe
- John P Rice
- John S Strauss
- John S Strauss
- Jolanta Lissowska
- Jonas Bybjerg-Grauholm
- Jonas Bybjerg-Grauholm
- Jonathan R I Coleman
- Jonathan R I Coleman
- Jordan W Smoller
- Jordan W Smoller
- Jordan W Smoller
- Josef Frank
- Josep Antoni Ramos-Quiroga
- Josep Antoni Ramos-Quiroga
- Josep Antoni Ramos-Quiroga
- Josep Antoni Ramos-Quiroga
- JoseĂŹ Guzman Parra
- Judith A Badner
- Julie Garnham
- Jun Z Li
- Jurgen Del-Favero
- Kari Stefansson
- Kari Stefansson
- Katherine Gordon-Smith
- Katrin Gade
- Katrin Gade
- Ketil J Oedegaard
- Ketil J Oedegaard
- Kimberly Chambert
- Laura Huckins
- Laura Huckins
- Laura J Scott
- Lena Backlund
- Liam Abbott
- Lili Milani
- Lilijana Oruc
- Lina Martinsson
- Lisa A Jones
- Liz Forty
- Loes M Olde Loohuis
- Louise FriseĂŹn
- Louise FriseĂŹn
- Louise FriseĂŹn
- Maciej Trzaskowski
- Manolis Kogevinas
- Manuel Mattheisen
- Manuel Mattheisen
- Manuel Mattheisen
- Manuel Mattheisen
- Manuel Mattheisen
- Marcella Rietschel
- Marco Boks
- Margarita Rivera
- Margarita Rivera
- Margit Burmeister
- Maria Grigoroiu-Serbanescu
- Maria Hipolito
- Marian L Hamshere
- Marianne GiĂžrtz Pedersen
- Marianne GiĂžrtz Pedersen
- Marianne GiĂžrtz Pedersen
- Marie BĂŠkvad-Hansen
- Marie BĂŠkvad-Hansen
- Marion Leboyer
- Marion Leboyer
- Marion Leboyer
- Mark Frye
- Mark J Daly
- Mark J Daly
- Markus Leber
- Markus M Nöthen
- Markus M Nöthen
- Marta RibaseĂŹs
- Marta RibaseĂŹs
- Marta RibaseĂŹs
- Martin Alda
- Martin Alda
- Martin Hautzinger
- Martin Schalling
- Matthew Flickinger
- Melissa J Green
- Melvin G McInnis
- Merete Nordentoft
- Merete Nordentoft
- Michael Bauer
- Michael Boehnke
- Michael C OâDonovan
- Michael Gill
- Michael J Owen
- Michael Steffens
- Michele T Pato
- Mikael LandeĂŹn
- Mikael LandeĂŹn
- Miquel Casas
- Miquel Casas
- Miquel Casas
- Miquel Casas
- Monika Budde
- Naomi R Wray
- Naomi R Wray
- Nelson B Freimer
- Ney Alliey-Rodriguez
- Niamh Mullins
- Nicholas Bass
- Nicholas Craddock
- Nicholas G Martin
- Nicholas G Martin
- Nicholas J Schork
- Olav B Smeland
- Olav B Smeland
- Olav B Smeland
- Olav Bjerkehagen Smeland
- Olav Bjerkehagen Smeland
- Ole A Andreassen
- Ole A Andreassen
- Ole A. Andreassen
- Ole A. Andreassen
- Ole Kristian Drange
- Ole Kristian Drange
- Ole Mors
- Ole Mors
- Oleksandr Frei
- Pablo Cervantes
- Pamela B Mahon
- Pamela B Mahon
- Pamela Sklar
- Pamela Sklar
- Pamela Sklar
- Pamela Sklar
- Panos Roussos
- Panos Roussos
- Panos Roussos
- Patrick F Sullivan
- Patrick F Sullivan
- Patrick F Sullivan
- Paul D Shilling
- Peng Zhang
- Per Hoffmann
- Per Hoffmann
- Per Hoffmann
- Per Hoffmann
- Per Ivar Finseth
- Peter A Holmans
- Peter McGuffin
- Peter R Schofield
- Peter R Schofield
- Peter Zandi
- Phil H Lee
- Phil H Lee
- Phil H Lee
- Philip B Mitchell
- Piotr M Czerski
- Preben Bo Mortensen
- Preben Bo Mortensen
- Preben Bo Mortensen
- Preben Bo Mortensen
- Psychiatric Genomics Consortium Bipolar Disorder Working Group
- Qingqin S Li
- Radhika Kandaswamy
- Ralph Kupka
- Ralph Kupka
- Ralph Kupka
- ReneĂŹ S Kahn
- ReneĂŹ S Kahn
- Richard Belliveau
- Richard M Myers
- Robert C Thompson
- Robert Karlsson
- Roel A Ophoff
- Roel A Ophoff
- Roel A Ophoff
- Rolf Adolfsson
- Roy H Perlis
- Roy H Perlis
- Sahar Hassani
- Sahar Hassani
- Sara A Paciga
- Sarah E Bergen
- Sarah E Medland
- Sarah Kittel-Schneider
- Sarah V Knott
- Sascha B Fischer
- Sascha B Fischer
- Scott D Gordon
- Sebastian Zollner
- Shaun M Purcell
- Shaun M Purcell
- Shawn E Levy
- Simon Xi
- Simone de Jong
- Simone de Jong
- Srdjan Djurovic
- Srdjan Djurovic
- Srdjan Djurovic
- Srdjan Djurovic
- Stacy Steinberg
- Stanley J Watson
- Stefan Herms
- Stefan Herms
- Stefan Herms
- Stefan Herms
- Stephan Ripke
- Stephan Ripke
- Stephan Ripke
- Stephan Ripke
- Stephanie H Witt
- Steve McCarroll
- Steve McCarroll
- SteĂŹphane Jamain
- SteĂŹphane Jamain
- Susan L McElroy
- Susanne Lucae
- Sven Cichon
- Sven Cichon
- Sven Cichon
- Sven Cichon
- Swapnil Awasthi
- Szabolcs Szelinger
- Tatiana M Foroud
- Tatyana Shehktman
- Thomas D Als
- Thomas D Als
- Thomas D Als
- Thomas G Schulze
- Thomas G Schulze
- Thomas G Schulze
- Thomas G Schulze
- Thomas G Schulze
- Thomas W MĂŒhleisen
- Thomas W MĂŒhleisen
- Thomas W Weickert
- Thomas W Weickert
- Thomas Werge
- Thomas Werge
- Thomas Werge
- Thorgeir E Thorgeirsson
- Tiffany A Greenwood
- Toni-Kim Clarke
- TorbjÞrn ElvsÄshagen
- TorbjÞrn ElvsÄshagen
- ToĂnu Esko
- ToĂnu Esko
- ToĂnu Esko
- ToĂnu Esko
- Tune H Pers
- Tune H Pers
- Udo Dannlowski
- Urban Ăsby
- Urs Heilbronner
- Valentina Escott-Price
- Vassily Trubetskoy
- Verneri Antilla
- Vishwajit Nimgaonkar
- Wade H Berrettini
- Wei Xu
- Wei Xu
- Weihua Guan
- Weiqing Wang
- Weiqing Wang
- William A Scheftner
- William B Lawson
- William Bunney
- William Byerley
- William Coryell
- Wolfgang Maier
- Yunpeng Wang
- Yunpeng Wang
- Yunpeng Wang
- Yunpeng Wang
- Publication venue
- 'Frontiers Media SA'
- Publication date
- 01/01/2019
- Field of study
Background: Alzheimer's disease (AD) and bipolar disorder (BIP) are complex traits influenced by numerous common genetic variants, most of which remain to be detected. Clinical and epidemiological evidence suggest that AD and BIP are related. However, it is not established if this relation is of genetic origin. Here, we applied statistical methods based on the conditional false discovery rate (FDR) framework to detect genetic overlap between AD and BIP and utilized this overlap to increase the power to identify common genetic variants associated with either or both traits. Methods: We obtained genome wide association studies data from the International Genomics of Alzheimer's Project part 1 (17,008 AD cases and 37,154 controls) and the Psychiatric Genetic Consortium Bipolar Disorder Working Group (20,352 BIP cases and 31,358 controls). We used conditional QQ-plots to assess overlap in common genetic variants between AD and BIP. We exploited the genetic overlap to re-rank test-statistics for AD and BIP and improve detection of genetic variants using the conditional FDR framework. Results: Conditional QQ-plots demonstrated a polygenic overlap between AD and BIP. Using conditional FDR, we identified one novel genomic locus associated with AD, and nine novel loci associated with BIP. Further, we identified two novel loci jointly associated with AD and BIP implicating the MARK2 gene (lead SNP rs10792421, conjunctional FDR=0.030, same direction of effect) and the VAC14 gene (lead SNP rs11649476, conjunctional FDR=0.022, opposite direction of effect). Conclusions: We found polygenic overlap between AD and BIP and identified novel loci for each trait and two jointly associated loci. Further studies should examine if the shared loci implicating the MARK2 and VAC14 genes could explain parts of the shared and distinct features of AD and BIP
Introduction: Linking Gender and Religion
- Author
- Ann Jeffers
- Anna Korteweg
- Anna Neubauer
- ANNA-KATHARINA HĂPFLINGER
- Anne Dafflon-Novelle
- ANNE LAVANCHY
- Anne Lavanchy
- Anne Lavanchy
- Anne Phillips
- Ayelet Shachar
- Ayhan Kaya
- bell hook
- Berger Peter L.
- Birgit Heller
- Birgit Heller
- Brent Plate S.
- Brent Plate S.
- Candace West
- Carol MacCormack
- Caroline PlĂŒss
- Christoph Bochinger
- Claudia Brunner
- Clifford Geertz
- Colette Guillaumin
- Crenshaw Kimberle W.
- Daria Pezzoli-Olgiati
- Daria Pezzoli-Olgiati
- Davis-Sulikowski Ulrike
- Denys Cuche
- Denzin Norman K.
- Donate Pahnke
- Donna Landry
- Edwin Ardener
- Francis Affergan
- Fred Dervin
- Friedrich Heiler
- Fritz Stolz
- Gabriele Dietze
- Gayle Rubin
- Gertrud HĂŒwelmeier
- Grace Davie
- Grace Davie
- Hanegraaff Wouter J.
- Harrison Jane Ellen
- Helma Lutz
- Henrietta Moore
- Hill Collins Patricia
- James Clifford
- Jan Feldman
- JANINE DAHINDEN
- Janine Joëlle Moret Dahinden
- Jean-Paul Willaime
- Jens Schlieter
- Jocelyne Cesari
- John Hinnells
- José Casanova
- Judith Butler
- Julia Eckert
- Juschka Darlene M.
- Jörg Stolz
- Kerstin Duemmler
- Kim Knott
- Laura Nader
- Leti Volpp
- Linda Woodhead
- Linda Woodhead
- Linda Woodhead
- Linda Woodhead
- Linda Woodhead
- Lorena Parini
- Maria Kromidas
- Maria Kromidas
- Milton Diamond
- Mohanty Chandra Talpade
- MĂŒller Friedrich Max
- Nancy Foner
- Nancy Fraser
- Peggy Levitt
- Philip Gorski
- Pierre Bourdieu
- Raewyn Connell
- Ralph Grillo
- Ralph Grillo
- Regine Gildemeister
- Rogers Brubaker
- Rosaldo Michelle Zimbalist
- Rosaldo Michelle Zimbalist
- Sara Ahmed
- Sharpe Eric J.
- Simone De Beauvoir
- Sirma Bilge
- Smith Jonathan Zittel
- Smith Jonathan Zittel
- Smith Wilfred Cantwell
- Spivak Gayatri Chakravorty
- Steven Vertovec
- Steven Vertovec
- Sue Morgan
- Susan Moller Okin
- Susanne Lanwerd
- SĂ©verine Rey
- Talal Asad
- Thomas Luckmann
- Ulrike Brunotte
- Ursula King
- Ursula King
- Ursula King
- Warne Randy R.
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/06/2012
- Field of study
Artropolis 90 : Lineages & Linkages
- Author
- Alice Mary
- Anonuevo Librado M.
- Aspell Peter
- Atkins Terryl
- Atkinson Clint
- Babcock Jennifer
- Balomenos Mary
- Banwell Mike
- Birkin Jeffrey
- Blackbridge Persimmon
- Blackstone Luke
- Blain Kim
- Boschman Lorna
- Bowley Janis
- Boyle Gwen
- Boyle Melanie Fei-Lin
- Bull Hank
- Burns Neil
- Burrows Tom
- Caetani Sveva
- Caruso Gordon
- Chaplin Carl
- Chappell Georgiana
- Cobbold Anna-Maria
- Cramer Barb
- Crane T.
- Cummins Jim
- de Courcy Michael
- Diamond Sara
- Dobereiner Wendy
- Doray Audrey
- Doucette Lionel
- Downe Mary
- Dyson Robert
- English Victoria
- Evans Diane
- Ewasiuk Terry
- Ewert Paul
- Falk Gathie
- Featherston Bill
- Forsythe Ian
- Fouquet Monique
- Frioud Jackie
- Gammon Lynda
- Gaskin Mark
- Gaudet Frank
- Gerberick Ken
- Gill Don
- Gillmore Graham
- Green Roy
- Greenberg Lorne
- Greer Lenna
- Grossmann Angela
- Guderna Ladislav
- Haag Joseph
- Hamlin Wendy
- Hatoum Mona
- Hogan Camp Mary
- Hogg Lucy
- Hornsby Michael
- Hueniken Heidi
- Hughes Patrick
- Huynh Kim
- Itter Carole
- Kellhammer Oliver
- Kempinsky Jean
- Kingan Ted
- Kipling Ann
- Kiyooka Roy
- Knott Tom
- Latremouille Lori-Ann
- Lawrence Donald
- Lay-Taq Laura Wee
- Levan Kaaaly
- Longboy Zachary
- Longman Mary
- Lowe Vanessa
- Lucas Launi
- Lukacs Attila Richard
- MacDonald Mike
- MacInnis Neil
- Mahon Patrick
- Manahan Jill
- Marshall Vicky
- Martin Anthony
- Massé Gloria
- Maxwell-Montgomery Claire
- McMurchy Patsi
- Mcp Art
- Mees Monique
- Menabney Joe
- Michener Sally
- Moiseiwitsch Carel
- Morgan Judith
- Mowat Fiona
- Muir Jim
- Musgrove Kurt
- Neil Al
- Neville Vaughn
- Nguyen Nhan
- Normoyle Michelle
- O'Brien Erin
- O'Hara Pat
- Okano Haruko
- Ostrem David
- Pan Davide
- Pantages Carrol
- Papou Laurie
- Payne Gordon
- Petterson Andre
- Pickard James
- Ramsden Anne
- Raphanel Philippe
- Rea Charles
- Rennie Bill
- Rice Chick
- Roberts David
- Root Derek
- Rosenberg Ann
- Rosenfeld Rhoda
- Rubenfeld Trudi
- Schorer Roman Pijanka
- Scott D. Blaire
- Scrivener Jack
- Searle Michele
- Semchuk Sandra
- Shadbolt Jack
- Shaw Nancy
- Shearer Steven
- Sherrin Bob
- Simpson Gregg
- Slater Anne Marie
- Slater Anne-Marie
- Smith Cynthia
- Smith Gordon
- Spicer Todd
- Steel Teresa
- Steele David
- Storey Sandra
- Switzer Allan
- Szekely Barrie
- Tait Sylvia
- Tate Kent
- Tate Scott
- Taylor Doug
- Thompson John
- Thorsen Katarina
- Todd Loretta
- Turner Richard
- Van Der May Robert
- Vander Zaag Elizabeth
- Vanier Barbara
- Varney Ed
- Varney Ed
- Wade Jan
- Walker David
- Watts John Clair
- Wedman Neil
- Westendorp Jan Koot
- Westlaken Shawn
- Whistler John
- Williams Carol
- Wilson Art
- Wise Robert Alan
- Wood Alan
- Wood Kelly
- Woods Chris
- Woycik Bruce
- Wyngaarden Cornelia
- Publication venue
- A.T. Eight Artropolis Society
- Publication date
- 01/01/1990
- Field of study
Varney documents the processes of organizing and mounting an exhibition of over 200 contemporary British Columbia artists. Includes artist's statements
Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database
- Author
- Ada Corrado
- Agneta Scheja
- Alan Doube
- Alan Tyndall
- Alberto Sulli
- Aleksandra Stankovic
- Alessandra Vacca
- Alessandro Mathieu
- Alexandra Balbir Gurmann
- Algirdas Venalis
- Alina Dumitrascu
- Allanore Y
- Ana M Gherghe
- Andrade Luis Eduardo C
- Andrea Himsel
- Andrea Lo Monaco
- André Kahan
- Anna Kotulska
- Annegret Kuhn
- Armando Gabrielli
- Bernard Coleiro
- Bernard Imbert
- Bianca Marasini
- Blaz Rozman
- Bojana Stamenkovic
- Branimir Anic
- Brigitte Granel
- Brigitte Krummel-Lorenz
- C Montecucco
- Camille FrancĂšs
- Carlo Chizzolini
- Carlos Alberto von MĂŒhlen
- Carlos de la Puente
- Carmel Mallia
- Carmen M Mihai
- Carol Black
- Carolina de Souza MĂŒller
- Cecile Durant
- Cecilia Varju
- Christian Beyer
- Codrina Ancuta
- Cord Sunderkötter
- Coziana Ciurtin
- Cristiane Kayser
- Cristina Pamfil
- Cristina-Mihaela Tanaseanu
- Czirjak L
- Daniel E Furst
- Daniela Opris
- Dante Valdetaro Bianchi
- David Launay
- Denton CP
- Diana Karpec
- Dinser R
- Distler O
- Dominique Farge-Bancel
- Dorota Krasowska
- Douglas Veale
- Duska Martinovic
- E L Nasanov
- Edoardo Rosato
- Eduardo Kerzberg
- Elisabeth Knott
- Ellen De Langhe
- Emmanuel Chatelus
- Eric Hachulla
- Esthela Loyo
- Eugen Russu
- Eugene J Kucharz
- Ewa Morgiel
- Ewa Wiesik-Szewczyk
- F Trotta
- Fabiana Montoya
- Fahrettin Oksel
- Felice Salsano
- Figen Yargucu
- Filip De Keyser
- Florenzo Iannone
- France Joyal
- Francesco Del Galdo
- Francesco Indiveri
- Francesco P Cantatore
- Franco Cozzi
- Frank Wollheim
- Fredrick M Wigley
- Frommer KW
- Frédéric A Houssiau
- Gabriela Udrea
- Gabriella SzĂŒcs
- Georg Schett
- Gianluigi Bajocchi
- Giovanna Cuomo
- Giovanni Lapadula
- Giselle Baptista Maretti
- Gitte Strauss
- Grodzicky Tamara
- Guido Valesini
- Harald Burkhardt
- Henrik Nielsen
- HĂ©lĂšne Chifflot
- Ileana Nicoara
- Ilka Herrgott
- Ina Kötter
- Ingo H Tarner
- Ira Litinsky
- Irena Butrimiene
- Isabela Tiglea
- Ivan CastellvĂ
- Jacek Olas
- Jacek Szechinski
- Jacob van Laar
- Jacques Eric Gottenberg
- Jadranka Morovic-Vergles
- Jean Luc Senécal
- Jean Sibilia
- Jerome Avouac
- JirĂ Ć tork
- Joanna Busquets
- Joanne Stephanie Schollum
- John Highton
- John O'Donnell
- Jose A RomĂĄn-Ivorra
- Jossiell Then
- José Antonio Pereira Da Silva
- Juan Jose Alegre-Sancho
- Jussara M Bohn
- Jörg Distler
- Kamal Solanki
- Kati Otsa
- Katrin Deuschler
- Kilian Eyerich
- Kirsten Damgaard
- Laura Belloli
- Lealea Chiaburu
- Lesley Ann Saketkoo
- Lesley Anne Bissel
- Lev N Denisov
- Lidia P Ananieva
- Lilian Scussel Lonzetti
- Liliana Groppa
- Line Iversen
- Lisa Maria Bambara
- Lisa Stamp
- Loc Guillevin
- Luc Mouthon
- Luis R Espinoza
- Luiza Fuocco
- Magdalena Kopec-Medrek
- Magdalena Szmyrka-Kaczmarek
- Malgorzata Widuchowska
- Margarita Pileckyte
- Maria JoĂŁo Salvador Henriques
- Maria Rosa Pozzi
- Maria Ăprus
- Marie O'Rourke
- Marie Vanthuyne
- Marko Baresic
- Marta Valero Exposito
- Martial Koenig
- Martin Aringer
- Marzena Olesinska
- Matthias Seidel
- Maurizio Cutolo
- Maya Buch
- Meier FMP
- Mengtao Li
- Merete Engelhart
- Michael Meurer
- Mihai Bojinca
- Mike Becker
- Miroslav Mayer
- Mislav Radic
- Mohammed Tikly
- Monica Popescu
- Muller-Ladner
- Murat Inanc
- N G Guseva
- Natalino H Yoshinari
- Nemanja Damjanov
- Nicolas Hunzelmann
- Nihal Fathi
- Nora Sandorfi
- Otylia Kowal-Bielecka
- P Vlachoyiannopoulos
- Paloma GarcĂa de la Pena Lefebvre
- Paloma GarcĂa de la Peña Lefebvre
- Paola Caramaschi
- Paolo AirĂČ
- Patricia E Carreira
- Patricia Senet
- Patrick Carpentier
- PatrĂcia Martin
- Paul Emery
- Paul Hasler
- Paulius Venalis
- Percival D Sampaio-Barros
- Peter Chapman
- Peter Villiger
- Pierluigi Meroni
- Piotr Wiland
- R La Corte
- Radim Becvar
- Raffaele Pellerito
- Raffaella Scorza
- Razvan Ionitescu
- Renata Sokolik
- Rene Westhovens
- Riemekasten G
- Rita Rugiene
- Roberta G Marangoni
- Roberto Caporali
- Rodica Chirieac
- Roger Hesselstrand
- Rosario Foti
- Roxana S Cornateanu
- Ruxandra Maria Ionescu
- RĂŒdiger Hein
- Sabine Adler
- Sara Pieropan
- SebastiĂŁo Cezar Radominski
- Senay Saritas
- Serena Guiducci
- Serena Vettori
- Sergei Popa
- Sergio Jimenez
- Sergio Toloza
- Silvana Zeni
- Silvia Rodriguez Rubio
- Simon Stebbings
- Simona Rednic
- Simonetta Pisarri
- Srdan Novak
- Stanislaw Sierakowsky
- Stefan Heitmann
- Sueli Carneiro
- Sule Yavuz
- Susanne Ullman
- Svetlana Agachi
- Szilvia Szamosi
- Tatiana Nevskaja
- Thierry Zenone
- Thomas Krieg
- Torhild Garen
- UEUSTAR Co-authors: Marco Matucci-Cerinic
- ValderĂlio FeijĂł Azevedo
- Valentini G
- Valeria Riccieri
- Vanesa Cosentino
- Vanessa Smith
- Vera Ortiz Santamaria
- Viktor Stoica
- Walid Ahmed Abdel Atty Mohamed
- Walker UA
- Washington Bianchi
- Wessam Harby Mohamed
- Yolanda Braun-Moscovici
- Zoltan Szekanecz
- Zora Marjanovic
- Ăyvind Midtvedt
- Publication venue
- 'BMJ'
- Publication date
- 01/01/2012
- Field of study
Objectives Systemic sclerosis (SSc) is a rare disease requiring multicentre collaboration to reveal comprehensive details of disease-related causes for morbidity and mortality.Methods The European League Against Rheumatism (EULAR) Scleroderma Trials and Research (EUSTAR) group initiated a database to prospectively gather key data of patients with SSc using a minimal essential dataset that was reorganised in 2008 introducing new items. Baseline visit data of patients who were registered between 2004 and 2011 were analysed using descriptive statistics.Results In June 2011, 7655 patients (2838 with diffuse cutaneous (dc) and 4481 with limited cutaneous (lc) SSc who fulfilled the American College of Rheumatology diagnostic criteria had been registered in 174 centres, mainly European. The most prominent hallmarks of disease were Raynaud's phenomenon (96.3%), antinuclear antibodies (93.4%) and a typical capillaroscopic pattern (90.9%). Scleroderma was more common on fingers and hands than on any other part of the skin. Proton pump inhibitors (65.2%), calcium channel blockers (52.7%), and corticosteroids (45.3%) were most often prescribed. Among the immunosuppressant agents, cyclophosphamide was used more often in dcSSc than in lcSSc.Conclusions The EUSTAR database provides an abundance of information on the true clinical face of SSc that will be helpful in improving the classification of SSc and its subsets and for developing more specific therapeutic recommendations
Effect of Antiplatelet Therapy on Survival and Organ SupportâFree Days in Critically Ill Patients With COVID-19
- Author
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Aguilar-Dano April
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Amri Ali
- Al Enezi Farhan
- Al Qasim Eman
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderink Bashar
- Alderman Meera
- Alegria Ana
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Farisha
- Ali Maryam
- Ali Murtaza
- Allam Hayat
- Allen Barbara
- Allen Louise
- Allibone Suzanne
- Alqahtani Samah
- Alswaidan Lolowa
- Altomy Mohammed
- Amatya Sameena
- Ambrosino Richard
- Anders Jeanette
- Anderson Thomas
- Andreae Mark
- Andric Zdravko
- Angus Derek
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
- Anthony Alpha
- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Apte Yogesh
- Arabi Yaseen
- Arachchige Malka
- Arbane Gill
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arias Sonia
- Arishi Hatim
- Arnold Donald
- Arnold John
- Aryal Diptesh
- Asif Namra
- Aspinwall Angelique
- Attanayaka Udara
- Attokaran Antony
- Attwood Ben
- Au Carly
- Austin Karen
- Austin Pauline
- Avard Bronwyn
- Awan Sidra
- Azaiz Amine
- Azergui Nora
- Azzaui Harun
- Babel JakĆĄa
- Babu Suresh
- Bacon Gina
- Badalamenti Salvatore
- Badie Julio
- Bagavathy Kavitha
- Bagot Catherine
- Bagshaw Sean
- Baig Nadia
- Baikady Ravishankar
- Baillie Kenneth
- Bain William
- Baker Evelyn
- Bakthavatsalam Dhanalakshmi
- Balaie Morteza
- Bamford Amy
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbash Ian
- Barbazza Leanne
- Barber Russell
- Barbier François
- Barge Deborah
- Bari Sara
- Bariola Ryan
- Barker Gareth
- Barnes Nicky
- Baron Rebecca
- Barreau Amelie
- Bart Robert
- Bartholdy Roland
- Bartley Shauna
- Barton David
- Barton Frances
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bassford Christopher
- Bastola Sirjana
- Bastos Joana Margarida Pereira Sousa
- Bates Michelle
- Bates Samantha
- Batista Teresa Margarida Oliveira
- Bauchmuller Kris
- Bean Sarah
- Beane Abi
- Beard Gregory
- Beasley Richard
- Beavis Sarah
- Bedford Caroline
- Beer Deborah
- Begin Phillipe
- Begum Salma
- Bell Gillian
- Bellemare David
- Beltran Mercedes
- Bendjemar Lynda
- Benettaib Fatna
- Bensen Nicole
- Benyon Sarah
- Benzekri Dalila
- Berdaguer Fernando
- Bergin Colin
- Berry Lindsay
- Berry Scott
- Berryman Emily
- Bertel Melanie
- Best-Lane Janis
- Besten Henny
- Bevan Emily
- Bewley Jeremy
- Beyerl Ashley
- Bhagani Sanjay
- Bhandal Khushpreet
- Bhattarai Binita
- Bhimani Zahra
- Bhonagiri Deepak
- Biddie Simon
- Bihari Shailesh
- Binnie Alexandra
- Biradar Vishwanath
- Birch Janine
- Birch Jenny
- Birchall Kathrine
- Birkinshaw Isobel
- Black Ethel
- Blackledge Bethany
- Blakemore Hayley
- Bland Yvonne
- Blank Elisabeth
- Bloos Frank
- Board Jasmin
- Bocher Simon
- Bociek Aneta
- Boivin Anne-HĂ©lĂšne
- Bojunga Jörg
- Bone Allison
- Bonner Stephen
- Bonten Marc
- Borgatta Barbara
- Borislavova Borislava
- Borrill Zoe
- Boschert Catherine
- Bossard Isabelle
- Boulanger Marie-Claude
- Boumahni Dounia
- Bouman Angela
- Bounab Rania
- Bourgoin Charlotte
- Bourne Michelle
- Bourne Richard
- Bouvier Elodie
- Bouw-Ruiter Marianne
- Boué Yvonnick
- Bowen James
- Bowler Helen
- Boyd Craig
- Boyles Rebecca
- Bracke Stephanie
- Bradbury Charlotte
- Bradley Paul
- Brady Kara
- Brailsford Jane
- Brain Matthew
- BrajkoviÄ Ana
- Brakké Karen
- Brant Emily
- Breen Patrick
- Bremmer Pamela
- Brennan Aoife
- Bretagnol Anne
- Brett Stephen
- Brewer Chris
- Brickell Kathy
- Brieger Klaus-Gerd
- Brightling Chris
- Brillinger Nicole
- Brimfield Lutece
- Brinkerhoff Gail
- Brochard Laurent
- Brohi Farooq
- Brooks Nicole
- Brown Cynthia
- Brown Louise
- Browne Troy
- Brugman Curt
- Brunetta Enrico
- Brunkhorst Frank
- Brunskill Nigel
- Bryan-Morris Kayla
- Buchanan Philip
- Budd Joanna
- Buehner Ulrike
- Buhay Megan
- Buhr Heidi
- Burbee Dylan
- Burda Dorota
- Burke David
- Burke Tara
- Burkey Jason
- Burnish Rachel
- Burns Dean
- Burns Karen
- Burrell Aidan
- Burt Karen
- Buscher Hergen
- Butler Amelia
- Butler Magdalena
- Buxton Meredith
- Buzgau Adrian
- Byrne Kathleen
- BĂ©lteczki JĂĄnos
- Cabrelli Louise
- Cabreros Leilani
- Cairns Tom
- Calfee Carolyn
- Callender Owen
- Cambalova Lenka
- Campbell Andrew
- Campbell Bridget
- Campbell Lewis
- Campbell Ryan
- Campisi Josie
- Campos Sara
- Camsooksai Julie
- Caplin Cecile
- Carbonneau Frédérick
- Carmona Rosario
- Carn Vanessa
- Carpio Lillian
- Carr-Wilkinson Joanne
- Carrier François
- Carrier Marc
- Carter Brittney
- Carter David
- Carter Jay
- Casali Sherry
- Casey Ruth
- Casey Siobhan
- Castelain Vincent
- Cathcart Susanne
- Catorze Nuno José Teodoro Amaro dos Santos
- Cattelan Jessy
- Cavayas Alexandros
- Cawley Kathryn
- Cazzola Federica
- Cecconi Maurizio
- Centofanti John
- Champanerkar Shreekant
- Chan Carmen
- Chan Charles
- Chan Peter
- Chapman Marianne
- Chapman Susan
- Charles Bethan
- Charles Walton
- Charlewood Richard
- Charlton Sam
- Charron Cyril
- Chartier Delphine
- Chasse Michael
- Chassé Michaël
- Chen Yan
- Cheng Allen
- Cherian Shiney
- Cheung Winston
- Chhablani Manish
- Chukkambotla Sri
- Ciccarelli Michele
- Cirstea Emanuel
- Clair Bernard
- Clark Michele
- Clark Richard
- Clark Sarah
- Clarke Frances
- Clarke Jennifer
- Claxton Andrew
- Clement Ian
- Clere-Jehl Raphael
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- van Bentum-Puijk Wilma
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- van der Heyden Kymbalee
- van der Kraan-Donker Annemarie
- van Gulik Laura
- van Kimmenade Roland
- van Nieuwkoop Kees
- van Oosten Nienke
- van Opdorp Marjolein
- van Vonderen Marit
- van Zanten Arthur
- van Zuylen Tamara
- Vanjak Christian
- Vanmali Piyush
- Vargas Jr. Jesus
- Varghese Siby
- Vautier Sarah
- Vazquez-Grande Gloria
- Veenith Tonny
- Venkatesh Bala
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- Verlander Mark
- Vermassen Joris
- Vermeiren Daisy
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- Vertue Mark
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- Viehman Alex
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- Vignesh C
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- Voigt Ingo
- Voiriot Guillaume
- Voza Antonio
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- Vuylsteke Alain
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- Wahl Nadine
- Waite Alicia
- Walden Andrew
- Walker Gena
- Walker Rachel
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- Walsh Tim
- Walsham James
- Wang Shu
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- Ward Kathryn
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- Warnock Majella
- Watchorn Olivia
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- Watkins Claire
- Watpool Irene
- Watts Angela
- Waugh Victoria
- Webb Steve
- Weber Lisa
- Weerasinghe Thanuja
- Weismann Dirk
- Weiss Daniel
- Weissman Alexandra
- Wells Colin
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- Westlake Samantha
- Wetherill Bill
- Wetzold Richard
- Whileman Amanda
- Whitbread Jennifer
- White Alison
- White Hayden
- White Ian
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- Whitehead Christina
- Whitehouse Tony
- Wibrow Bradley
- Wigbers Jeanette
- Wilby Elizabeth
- Wilcox Elizabeth
- Wilcox Louise
- Wild Helen
- Wild Laura
- Wilding Laura
- Wiles Matt
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Angharad
- Williams Anna
- Williams Erin
- Williams Gemma
- Williams Karen
- Williams Patricia
- Williams Tony
- Williams Virginie
- Willis Joanna
- Willson Jayne
- Wilson Anna
- Wilson Craig
- Wilson Maggie
- Winters James
- Winters Lauren
- Wise Matt
- Wiseman Sophie
- Wisniewski Mary
- Wittenberg Wendy
- Wnuk Chris
- Woelke Amy
- Wong Helen
- Wong Onyee
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Wright Chris
- Wunderley Renee
- Wyatt Rachel
- Wylie Katharine
- Xavier Kugan
- Yang Yang
- Yarad Elizabeth
- Yates David
- Yealy Donald
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Youngstein Taryn
- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Äimoti Renata
- Publication venue
- American Medical Association
- Publication date
- 05/04/2022
- Field of study
International audienc
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial
- Author
- Abrams Judith
- Adda Mireille
- Adderley Jane
- Adhikari Neill K. J.
- Adhikari Neill K. J.
- Aissaoui Nadia
- Alam Ahsan
- Albrett Jonathan
- Albright Robert C.
- Alcuaz Victoria
- Allam Hayat
- Altarelli Marco
- Amaral Andre
- Amsbaugh Amy
- Anderson Felicity
- Andreu Pascal
- Antunes Veronica
- Arbane Gill
- Argaud Laurent
- Arias Castro
- Asehnoune Karim
- Attwood Ben
- Auld Fiona
- Ayas Najib
- Aycinena Juan Carlos
- Azais Marie-Ange
- Bachler Mirjam
- Backhouse Felicity
- Bagshaw Sean M.
- Bagshaw Sean M.
- Bagshaw Sean M.
- Bagshaw Sean M.
- Baharlo Behrad
- Bai Guoqiang
- Bai Jing
- Baig Nadia
- Baig Nadia
- Bailey Matthew
- Baker Nerilee
- Ball Ian M.
- Ball Jonathan
- Barbar Saber Davide
- Barbier François
- Barchard Jennifer
- Bass Frances
- Bates Samantha
- Baudry Thomas
- Beck James
- Beehre Nina
- Bellemare David
- Belley-Cote Emilie
- Bellmann Romuald
- Bellomo Rinaldo
- Bellomo Rinaldo
- Benettaib Fatna
- Benoit Luc
- Benton Jane
- Benzekri Dalila
- Bergin Colin
- Bihari Shailesh
- Bihorac Azra
- Bird Sarah
- Bitker Laurent
- Board Jasmin
- Bociek Aneta
- Bohé Julien
- Boisrame-Helms Julie
- Boivin Annick
- Bojic Andja
- Bone Allison
- Boschert Catherine
- Bouisse Camille
- Boulain Thierry
- Boulet Ăric
- Boumahni Dounia
- Bourchard Pierre-Alexandre
- Bowman Katie
- Bracke Stephanie
- Bradford Celia
- Brailsford Jane
- Brandtner Anna
- Bretagnol Anne
- Brickell Kathy
- Broadfield Emma
- Brodutch Shira
- Brooks Jenny
- Brown Gillian
- Brown Sherry
- Browne Troy
- Buehner Ulrike
- Buhr Heidi
- Burke Tara
- Burns Karen
- Buscher Hergen
- Butler Magdalena
- Butler Susie
- Cahill Hazel
- Cailhier Jean-François
- Callahan Jean Christophe
- Callender Owen
- Campbell Eileen
- Campbell Troy
- Campbell Victoria
- Campisi Josie
- Camporota Luigi
- Campos Sara
- Canet Emmanuel
- Cantien Marie
- Carbonnaeu Ălaine
- Carles Michel
- Carney Dominic
- Carney Gayle
- Carpentier Dorothée
- Carrera Ron
- Carrier François-Martin
- Carson Joshua
- Carter Joseph
- Carungcong Jaime
- Carvelli Paula
- Cegarra Santiago
- Cennamo Armando
- Chadbourn Indra
- Chadwick Lesley
- Chan Peter
- Chee Nigel
- Chen Man
- Chen Yan
- Chen Zhenzhen
- Chenaf Samir
- Cheung Winston
- Chevrel Guillaume
- Chiella Bianca
- Chimunda Tim
- Chudeau Nicolas
- Cinotti Raphaël
- Cirone Robert
- Clarey Emma
- Clark Amy
- Clark Edward
- Clark Michele
- Clarke France
- Cleophax Cedric
- Clere-Jehl Raphael
- Cloutier Eve
- Cohen Yves
- Cole Jade
- Cole Louise
- Coles Jennifer
- Colin Gwenhaël
- Collins Amy
- Combes Alain
- Commeureuc Morgane
- Condin Christopher
- Conner Louise
- Cooper Lauren
- Corcoran Eleanor
- Costa Patricia
- Costerousse Olivier
- Coupez Elisabeth
- Cour Martin
- Cowdrey Keri-Anne
- Creary Thais
- Crosby Laura
- Cross Rosalba
- Cunningham Mishell
- Cupka Julie
- da Costa Bruno R.
- Daniels Alison
- Dargent Auguste
- Davies Tracy Michelle
- De Crop Luc
- De La Salle Sylvie
- De Prost Nicolas
- De Watteville Aude
- Decalvele Maxens
- Dechanet Aline
- Dekeyser Thibault
- Delabranche Xavier
- Delaney Anthony
- Delecolle Lucie
- Delgado Carlos Castro
- Delisle-Thibault Charles
- Demeure Dominique
- Demiri Suela
- Demoule Alexandre
- Deng Fuxing
- Derrien Benoit
- Despy Liesl
- Dessap Armand Mekontso
- Devereaux Kelson
- Di Nella Michelle
- Diehl Jean-Luc
- Diel Naomi
- Dignam Gemma
- Dilawershah Maria
- Ding Lili
- Ding Ruiqi
- Ditlbacher Adelheid
- Dodek Peter
- Dominy Clive
- Dong Lei
- Dong Xin
- Dooley Natalie
- Doran Peter
- Dorfman Robert
- Dos Santos Sandra
- Dres Martin
- Dreyfuss Didier
- Dreyfuss Didier
- Drover John
- Du Bin
- Du Bin
- Duan Meili
- Duffy Jane
- Duffy Karina
- Dufour Nicolas
- Duggan Shelley
- Duke Graeme
- Dun Shijuan
- Dyett John
- DâAragon FrĂ©dĂ©rick
- Eastwood Glenn M.
- Eckert Philippe
- Efron Philip
- Elderkin Tania
- Elias Madona
- Elizabeth Wilcox M.
- Eller Philipp
- Ellis Karen
- Emery Malo
- Endre Zoltan
- Ensenyat-Martin Luis
- Eraldi Jean-Pierre
- Fadel Fouad
- Fan Jingqun
- Farnell-Ward Sarah
- Farrah Helen
- Faure Morgane
- Felix Luis
- Fellows Emma
- Fendt Lucia
- Fennessy Gerard
- Fiancette Maud
- Finfer Simon
- Finkenstedt Armin
- Finney Clare
- Fletcher Jason
- Forbes Loretta
- Forni Lui G.
- Forshaw Greg
- Foulkes Stephen
- Francoeur Charles Langis
- Franja Vincenta
- Freebairn Ross
- French Craig
- Friedrich Jan
- Fries Dietmar
- Fu Lijuan
- Fu Yongjian
- Fusco Kelly
- Gallagher Martin P.
- Gallagher Martin P.
- Gangopadhyay Himangsu
- Gantner Dashiell
- Gao Lan
- Garg Amit
- Gattas David
- Gatward Jonathan
- Gaudry Stéphane
- Gaudry Stéphane
- George Aparna
- Georgescu Ilinca
- Gernez Coralie
- Ghamraoui Ali
- Ghate Taneera
- Ghosh Angaj
- Giannakouros Panagiota
- Gibson Neil
- Giebel Shelley
- Gilder Eileen
- Glybina Anna
- Gomes Brigette
- Gomez Raquel
- Goodson Jennifer
- Gordon Boyd J.
- Goulart Joyce McKenney
- Goulart Joyce McKenney
- Goundry Stephanie
- Grainger Lia
- Grangé Steven
- Grant Alice
- Grant Caroline
- Gray Geraldine
- Grenier Stéphanie
- Gresham Rebecca
- Grillot Nicolas
- Guerot Emmanuel
- Guery Aurore
- Guilbault Gabrielle
- Guitton Christophe
- Guo Dongchen
- Guo Litao
- Gurung Babita
- Gutierrez David
- Guy Zoe
- Haljan Gregory
- Hall Adam
- Hallion Jane
- Haltia Paivi
- Hambrook Geraldine
- Hammond Naomi
- Hamshere Alexandra
- Hang Lele
- Harasemiw Oksana
- Harkett Samanth
- Harkins Margaret
- Harmon John
- Harris Claire-Louise
- Harrop Clare
- Hartig Frank
- Harvey Dan
- Hashemighouchani Haleh
- Haslam Nicole
- Hasslacher Julia
- Hauschild Caroline
- Hazelton Tracy
- He Xiandi
- He Xiaona
- Heidegger Claudia
- Heinonen Jonna
- Henderson Seton
- Henderson Steven
- Hendry Deborah
- Hernandez Clara
- Hernu Romain
- Herridge Margaret S.
- Higson Vicki
- Hill Dianne
- Hill Helen
- Hindle Julia
- Hiremath Swapnil
- Hirst Claire
- Hodder Jennifer
- Hodgson Luke E.
- Hopkins Philip
- Hoppu Sanna
- Hoste Eric
- Hou Guo
- Houghton James
- Howard Kate
- Howcroft Clare
- Howe Elizabeth
- Howlett Luisa
- Hu Chenghuan
- Hu Tingting
- Hu Xiaobo
- Huang Lili
- Huang Yingzi
- Hunt Anna
- Hunt Miranda
- Hunter Stephanie
- Hussain Nauman
- Hutch Debra
- Inkinen Outi
- Investigators STARRT-AKI
- Jackson Carolyn
- Jackson David
- Jagannathan Vijay
- Jalkanen Ville
- Jang Ryan
- Janin Pierre
- Ji Xiaojun
- Jim Kym
- Jin Xia
- Joannidis Michael
- Joannidis Michael
- Johnson Emily
- Johnston Andy
- Joseph Gipsy
- Judd Harriet
- Junge Andrea
- JĂ€rvisalo Mikko J.
- Kamel Toufik
- Kapoor Ritoo
- Karachi Tim
- Karlsson Sari
- Kashani Kianoush B.
- Kaufman Melissa
- Kaur Navjot
- Kavikondala Kanthi
- Kaye Callum
- Keet Owen
- Kentala Satu
- Kerr Deborah
- Khalid Imrana
- Ki Vincent
- Kiley Sean
- Kirkham Simon
- Kissling SĂ©bastien
- Klein David
- Klein Sebastian
- Knight David
- Knott Cameron
- Koglberger Paul
- Kokotsis Nicos
- Kol Mark
- Koottayi Sathyajith
- Korhonen Anna-Maija
- Kruger Peter
- Kuitunen Anne
- Kummerlen Christine
- Kutsogiannis Demetrios J.
- KĂŒllmar Mira
- Lacave Guillaume
- Lacherade Jean Claude
- Ladouceur MarilĂšne
- Lafrance Jean-Philippe
- Lagarrigue Matthieu Henry-
- Lakatos Louis
- Lakhal Karim
- Lambert Bridget
- Lamontagne François
- Lamontagne François
- Lamontagne François
- Landais Mickael
- Landoni Giovanni
- Lapinsky Stephen
- Lappi Eliria
- Large Audrey
- Latimer-Bell Charlotte
- Latta Laura
- Laurie Gordon
- Lauzier François
- Lawrence Cassie
- Le Moal CharlĂšne
- Leaver Susannah
- Lebert Christine
- LeBlanc Guillaume
- Lebrasseur Martine
- Lee Sandra
- Leivo Keijo
- Lellouche Francois
- Lembo Rosalba
- Lenga Ilan
- Lesona Eden
- Levoranta Markus
- Li Hao
- Li Jian
- Li Jianquan
- Li Jing
- Li Min
- Li Nan
- Li Rui
- Lian Yingtao
- Liangos Orfeas
- Licari Elisa
- Lim Rosario
- Lin Jin
- Lin Jincan
- Liu Airan
- Liu Cheng
- Liu Hongjuan
- Liu Jingfeng
- Liu Kathleen D.
- Liu Manli
- Liu Pei
- Liu Xingang
- Liu Yu
- Liu Zhongmin
- Liu Zhou
- Liu Zhuang
- Lizotte Patricia
- Lobaz Steve
- Lombardi Gaetano
- Long Dali
- Long Stephanie
- Lord Jenny
- Lowrey Julie
- Lu Kun
- Lu Liping
- Lyas Claretha
- Lynch Matthew
- Lynch Matthew
- LÄngsjö Jaakko
- Ma Hongye
- MacIntyre Erika
- Magder Sheldon
- Maguire Teena
- Maizel Julien
- Malila Kaisa
- Mallaird Samia Abed
- Mallet Maxime
- Manns Braden J.
- Manso Katarina
- Marceron Alina
- Marchalot Antoine
- Marchand Joannie
- Margalef Jordi
- Margarson Michael
- Marinoff Nicole
- Marios Clémence
- Marotti Martina
- Marque Sophie
- Martin Emma
- Martin-Lefevre Laurent
- Martino Frédéric
- Martins Laura
- Marzaroli Matteo
- Marzouk Mehdi
- Masi Paul
- Maslove David
- Mason Chris
- Mason Sophie
- Mason Tracy
- Masse Marie-HĂ©lĂšne
- Masters Kristy
- Matheson Elisha
- Mathonnet Armelle
- Mayaux Julien
- Mayette Michael
- Mazer David
- McArthur Colin
- McAuley Daniel F.
- McAuley Danny F.
- McCall Philip
- McClure Jason
- McConnochie Rachael
- McCoshen Lorena
- McCracken Phoebe
- McGain Forbes
- McGlone Philip
- McGloughlin Steve
- McGonigal Elizabeth
- McGuinness Shay
- McGuinness Shay
- McGuinness Shay P.
- McIntyre Lauralyn
- Mckay-Vucago Agnes
- McKerrow Elizabeth
- McLaughlan Derek
- Meehan Sharon
- Mehrtens Jan
- Mehta Navdeep
- Mehta Sangeeta
- Mei Huaxian
- Mei Jing
- Meng Zhaoli
- Merdji Hamid
- Meredith Megan
- Messika Jonathan
- Mew Louise
- Meyer Jason
- Meziani Ferhat
- Millen Tina
- Mitchell Wendy
- Mo Min
- Monnier Alexandra
- Monti Giacomo
- Montillier Philippe
- Moon Angela
- Mooney Owen
- Morawiec Elise
- Moreland Gayle
- Morgan Matt
- Morgan Rebecca
- Morgan Stacey
- Morizot Laura
- Morris Anna
- Moser Max
- Mu Sijie
- Mulder John
- Muller Grégoire
- Muller Lucie
- Murray Lauren
- Murray Patrick T.
- Muscedere John
- Musselwhite Janine
- Mwaura Esther
- Naeem Syed
- Naeem Syed
- Naud Jean-François
- Navarra Leanlove
- Nay Mai-Anh
- Neal Philippa
- Needham Matthew
- Neils Seigenthaller
- Newby Lynette
- Neyra Javier A.
- Nichol Alistair
- Nichol Alistair D.
- Nichol Alistair D.
- Nichol Alistair D.
- Nicholson Alice
- NiChonghaile Martina
- Nicolet Laurent
- Nieszkowska Ania
- Niven Alexander S.
- Niven Daniel J.
- Noble Harriet
- Noel Gibney R. T.
- Norris Sean
- Novellas Neus Grau
- Ogg Bethan
- Okubanjo Maryanne
- Olatunji Shaanti
- Omalay George
- Ordon Marie Amélie
- Orford Neil
- Ortiz-Soriano Victor M.
- Ostermann Marlies
- Ostermann Marlies
- Ostermann Marlies
- Ovakim Daniel
- Ovsenek Athena
- Oxtoby Kerry
- Oziemski Peter
- OâMara AnnMarie
- OâMara AnnMarie
- Padayachee Laven
- Palevsky Paul M.
- Pan Chun
- Pan Yu
- Park Penelope
- Parke Rachael
- Parsons Penny
- Patel Alpesh
- Paternoster Gianluca
- Patrick-Heselton Julie
- Paunovic Bojan
- Peck Leah
- Peer Andreas
- Pelletier Celine
- Perez Adic
- Perret Aurelie
- Peters Cecilia
- PettilÀ Leena
- PettilÀ Ville
- PettilÀ Ville
- Phull Mandeep-Kaur
- Pitts Sally
- Pogreban Tatiana
- Poirson Florent
- Poli Elettra
- Polychronopoulos Erietta
- Pons Bertrand
- Porteous Rebecca
- Porwal Sanjay
- Pouplet Caroline
- Pousset François
- Pradet Amandine
- Prasad Bhanu
- Prendergast Clara
- Pretorius Rinus
- Purv Sarah
- Qi Guoqing
- Qi Zhili
- Qin Bingyu
- Qin Suhui
- Qiu Haibo
- Qiu Yu
- Quenot Jean-Pierre
- Qui Haibo
- Rabouel Yannick
- Rahmani Hassene
- Rahmani Imen
- Raithatha Ajay
- Ramsey Judith
- Rao Jag
- Rattray Austin
- Razazi Keyvan
- Reece-Anthony Rosie
- Reignier Jean
- Rewa Oleksa
- Rewa Oleksa
- Reynolds Claire
- Ricard Jean-Damien
- Richard RĂ©gine
- Richardson Angus
- Richardson Max
- Rigatto Claudio
- RistimÀki Sanna
- Robert Alain
- Robertson Yvonne
- Robine Adrien
- Robinson Chelsea
- Robinson Francesca
- Robinson Holly
- Rochwerg Bram
- Rochwerg Bram
- Rogers Paula
- Rokosh Ella
- Rolls Christine
- Romano Martin
- Romanovsky Adam S.
- Roodenburg Owen
- Rose Bernd Oliver
- Rosenberg Alex
- Rosenow Nadine
- Roshdy Ashraf
- Rossi Julie
- Roux Damien
- Roux Sylvie
- Roy Isabelle
- Rozec Bertrand
- Ruddell Stacey
- Ruddell Stacey
- Ruddy Jim
- Ruppert Matthew
- Russell Michael
- Ryan Lucy
- Sabev Alexandra
- Said Simone
- Salamé Maya
- Salerno Tania
- Salva Juvy
- Sandhu Gyan
- Sangla Frederic
- Santos Marlene
- Savija Nevena
- Saylor Emma
- Schellongowski Peter
- Schenk Bettina
- Scherr Kimberly
- Schneider Antoine G.
- Schneider Antoine G.
- Schnorf Madeleine
- Schwartz Kate
- Scott Teresa
- Sedillot Nicholas
- Seguin Amélie
- Sejourne Caroline
- Shah Asim
- Shah Sumesh
- Shami Aysha
- Shanmugasundaram Pradeep
- Sharif Sairah
- Sharif Sairah
- Sharman Andrew
- Sharman Asheer
- Shaw David
- Shelley Ben
- Sheng Lulu
- Shi Qindong
- Shi Xianqing
- Shrestha Tapaswi
- Shuker Karen
- Sia Ying Tung
- Sibley Stephanie
- Sim Malcolm
- Simmonds Catherine
- Simon Marie
- Simon Mathieu
- Singh Gurmeet
- Skarzynski Marie
- Slack Andrew
- Smith John
- Smith Julie
- Smith Orla M.
- Snelson Catherine
- Sokolowski Colleen
- Soth Mark
- Souweine Bertrand
- Sparkes Simon
- Spruce Elaine
- Sridhar Kavita
- St-Arnaud Charles
- Staudinger Thomas
- Steele Andrew
- Stelfox Henry T.
- Stelfox Henry T.
- Stewart Richard
- Stoltenberg Anita
- Suen Gabriel
- Suhonen Taria
- Sun Jingjing
- Sutherland Sara-Beth
- Sutinen Sari
- Takaoka Alyson
- Tamion Fabienne
- Taneja Ravi
- Tchenio Xavier
- Thevenin Didier
- Thevenin Fabienne
- Thibault Michel
- Thiéry Guillaume
- Thomas Emma
- Thomas Liz
- Thome Fernando
- Thompson Patricia
- Thompson Tayne
- Thuong Marie
- Tiagarajah Abirami
- Tiller Esther
- Tilley Rosalinde
- Tippett Anna
- Titeca-Beauport Dimitri
- Tolibas Michael
- Tolwani Ashita
- Towns Miriam
- Tozzi Margherita
- Tridente Ascanio
- Trusson RĂ©mi
- Tung Ying
- Turgeon Alexis F.
- Törnblom Sanna
- Udy Andrew
- Vaara Suvi
- Vaara Suvi T.
- Vaara Suvi T.
- Vallance Shirley
- Vamplew Luke
- van Diepen Sean
- van Waegeningh Thomas
- Van Hoa Dang
- Vander Hayden Kymbalee
- Varila Simo
- Veenith Tonny
- Velez Laura
- Venz Ellen
- Verlay MĂ©lanie
- Vermeiren Daisy
- Vetro Joseph
- Vimpere Damien
- Vinatier Isabelle
- Vinsonneau Christophe
- Vitiello Michelangelo
- Vizcaychipi Marcela
- Vladic Chelsey
- Wagner Martin
- Walczak Karolina
- Wald Ron
- Wald Ron
- Wald Ron
- Wallace Samantha
- Wang Amanda Y.
- Wang Chuanyao
- Wang Chunting
- Wang Cunzhen
- Wang Dongxin
- Wang Haibo
- Wang Haiman
- Wang Jane
- Wang Jinlong
- Wang Kaiwu
- Wang Peng
- Wang Qizhi
- Wang Quihui
- Wang Xue
- Wang Yifeng
- Ward Geraldine
- Watpool Irene
- Watson Hayley
- Waugh Victoria
- Wax Randy
- Weir Matthew
- Weir Matthew A.
- Welsh Deborah
- Welters Ingeborg
- Wen Mingxiang
- Wetzig Krista
- White Peggy
- Whitehead Christina
- Whitehouse Tony
- Whitlock Richard P.
- Wilby Elizabeth
- Williams Erin
- Williams Karen
- Willox Fiona
- Wise Matthew
- Wittig Monika
- Wolverson Adam
- Wong Helen
- Wood Gordon
- Woolett Melissa
- Wootten Anna
- Wren Lynn
- Wu Changde
- Wu Jing
- Wun James
- Wyncoll Duncan
- Xu Hao
- Xu Song
- Yan Jie
- Yan Jinqi
- Yang Enyu
- Yang Jianxu
- Yang Juan
- Yang Yang
- Yang Yi
- Yang Ziqi
- Yao Han
- Yao Lan
- Yarad Elizabeth
- Ye Baning
- Yehia Aihem
- Young Helen
- Young Meredith
- Young Paul
- Youngs Nora
- Yu Zhui
- Zahirieh Alireza
- Zampieri Fernando G.
- Zangrillo Alberto
- Zarbock Alexander
- Zeng Qinjing
- Zhang Jichen
- Zhang Lei
- Zhang Meng
- Zhang Minwei
- Zhang Songsong
- Zhao Dan
- Zhao Mengya
- Zhao Shibing
- Zhao Shuangping
- Zhi Deyuan
- Zhou Qi
- Zhou Xiao
- Zhuang Haizhou
- Zotter Klemens
- Zuber Benjamin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Background
Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial compared two strategies of KRT initiation (accelerated versus standard) in critically ill patients with acute kidney injury and found neutral results for 90-day all-cause mortality. Probabilistic exploration of the trial endpoints may enable greater understanding of the trial findings. We aimed to perform a reanalysis using a Bayesian framework.
Methods
We performed a secondary analysis of all 2927 patients randomized in multi-national STARRT-AKI trial, performed at 168 centers in 15 countries. The primary endpoint, 90-day all-cause mortality, was evaluated using hierarchical Bayesian logistic regression. A spectrum of priors includes optimistic, neutral, and pessimistic priors, along with priors informed from earlier clinical trials. Secondary endpoints (KRT-free days and hospital-free days) were assessed using zeroâone inflated beta regression.
Results
The posterior probability of benefit comparing an accelerated versus a standard KRT initiation strategy for the primary endpoint suggested no important difference, regardless of the prior used (absolute difference of 0.13% [95% credible interval [CrI]âââ3.30%; 3.40%],âââ0.39% [95% CrIâââ3.46%; 3.00%], and 0.64% [95% CrIâââ2.53%; 3.88%] for neutral, optimistic, and pessimistic priors, respectively). There was a very low probability that the effect size was equal or larger than a consensus-defined minimal clinically important difference. Patients allocated to the accelerated strategy had a lower number of KRT-free days (median absolute difference ofâââ3.55 days [95% CrIâââ6.38;âââ0.48]), with a probability that the accelerated strategy was associated with more KRT-free days of 0.008. Hospital-free days were similar between strategies, with the accelerated strategy having a median absolute difference of 0.48 more hospital-free days (95% CrIâââ1.87; 2.72) compared with the standard strategy and the probability that the accelerated strategy had more hospital-free days was 0.66.
Conclusions
In a Bayesian reanalysis of the STARRT-AKI trial, we found very low probability that an accelerated strategy has clinically important benefits compared with the standard strategy. Patients receiving the accelerated strategy probably have fewer days alive and KRT-free. These findings do not support the adoption of an accelerated strategy of KRT initiation