Is This Transfer Shock ? Examining the Perceptions of Engineering Students Who Articulate Within the Irish Higher Education Context.

Abstract—“Transfer shock” is a well-known phenomenon during the process of articulation, when students move from short-cycle applied programs to more academic longer-cycle study programs. In the US context this problematic transition has been observed in students transferring from community colleges into the traditional university system. In Ireland’s binary higher education structure, one set of institutions, known as Institutes of Technology (IoTs) allow for this transition to take place entirely within individual institutions. This paper is part of an ongoing investigation into one such IoT, where engineering students who achieve high grades at the end of 3-year (so-called Level 7) “ordinary degree” programs frequently transfer into the 3rd year of 4-year Level 8 “honors degree” programs, with surprisingly successful outcomes. One surprise derives from the fact that the students who enter Level 7 engineering programs are deemed at the outset to be academically less able, particularly in mathematics, than those who go directly into Level 8 programs from secondary school. Relatively little work has been done on this transition to date. In the 3rd and 4th year of many honors engineering programs within this institution it is not unusual to have 30-50% of the students coming from an ordinary degree background, the majority from within the institution itself – with others transferring from other IoTs in Ireland. Previous research has shown that students from this background initially struggle in the 3rd year of the honors degree program when compared with students who have proceeded directly through the honors program, before going on to successfully graduate. Can this be attributed to ‘transfer shock’; even though most of these students are continuing in an institution and with faculty that they are already familiar with? In order to examine this phenomenon we interview students from several engineering disciplines at various points in this transition. We explore the perceptions of the students regarding this transition and, based on the information coming from the interviews, we conduct a large scale survey to be administered to articulating students across engineering programs in the institution. The preliminary results of this survey are also presented here

Dynamic Balance In Children: Performance Comparison Between Two Testing Devices

Please view abstract in the attached PDF file

Acute Cardiometabolic Responses to Medicine Ball Interval Training in Children

International Journal of Exercise Science 11(4): 886-899, 2018. Medicine ball interval training (MBIT) has been found to be an effective exercise modality in fitness programs, yet the acute physiological responses to this type of this exercise in youth are unknown. The purpose of this study was to examine the acute cardiometabolic responses to MBIT in children. Fourteen children (mean age 10.1 ± 1.3 yr) were tested for peak oxygen uptake (VO2peak) on a treadmill and subsequently (\u3e 48 hours later) performed a progressive 10 min MBIT protocol of 5 exercises (EX): standing marches (EX1), alternating lunges (EX2), squat swings (EX3), chest passes (EX4) and double arm slams (EX5). A 2.3 kg medicine ball was used for all trials and each exercise was performed twice for 30 sec with a 30 sec rest interval between sets and exercises. Participants exercised while connected to a metabolic system and heart rate (HR) monitor. During the MBIT protocol, mean HR significantly (p\u3c0.05, η2= 0.89) increased from 121.5 ± 12.3 bpm during EX1 to 178.3 ± 9.4 bpm during EX5 and mean VO2 significantly (p\u3c0.05, η2= 0.88) increased from 15.5 ± 2.9 ml ×kg-1×min-1during EX1 to 34.9 ± 5.1 ml ×kg-1×min-1during EX5. Mean HR and VO2values during MBIT ranged from 61.1% to 89.6% of HRpeak and from 28.2% to 63.5% of VO2peak. These descriptive data indicate that MBIT can pose a moderate to vigorous cardiometabolic stimulus in children

Defective adaptive thermogenesis contributes to metabolic syndrome and liver steatosis in obese mice

Abstract Fatty liver diseases are complications of the metabolic syndrome associated with obesity, insulin resistance and low grade inflammation. Our aim was to uncover mechanisms contributing to hepatic complications in this setting. We used foz/foz mice prone to obesity, insulin resistance and progressive fibrosing non-alcoholic steatohepatitis (NASH). Foz/foz mice are hyperphagic but wild-type (WT)-matched calorie intake failed to protect against obesity, adipose inflammation and glucose intolerance. Obese foz/foz mice had similar physical activity level but reduced energy expenditure. Thermogenic adaptation to high-fat diet (HFD) or to cold exposure was severely impaired in foz/foz mice compared with HFD-fed WT littermates due to lower sympathetic tone in their brown adipose tissue (BAT). Intermittent cold exposure (ICE) restored BAT function and thereby improved glucose tolerance, decreased fat mass and liver steatosis. We conclude that failure of BAT adaptation drives the metabolic complications of obesity in foz/foz mice, including development of liver steatosis. Induction of endogenous BAT function had a significant therapeutic impact on obesity, glucose tolerance and liver complications and is a potential new avenue for therapy of non-alcoholic fatty liver disease (NAFLD)

Diagnosis of Cystic Fibrosis in Screened Populations

Objective Cystic fibrosis (CF) can be difficult to diagnose, even when newborn screening (NBS) tests yield positive results. This challenge is exacerbated by the multitude of NBS protocols, misunderstandings about screening vs diagnostic tests, and the lack of guidelines for presumptive diagnoses. There is also confusion regarding the designation of age at diagnosis. Study design To improve diagnosis and achieve standardization in definitions worldwide, the CF Foundation convened a committee of 32 experts with a mission to develop clear and actionable consensus guidelines on diagnosis of CF with an emphasis on screened populations, especially the newborn population. A comprehensive literature review was performed with emphasis on relevant articles published during the past decade. Results After reviewing the common screening protocols and outcome scenarios, 14 of 27 consensus statements were drafted that apply to screened populations. These were approved by 80% or more of the participants. Conclusions It is recommended that all diagnoses be established by demonstrating dysfunction of the CF transmembrane conductance regulator (CFTR) channel, initially with a sweat chloride test and, when needed, potentially with newer methods assessing membrane transport directly, such as intestinal current measurements. Even in babies with 2 CF-causing mutations detected via NBS, diagnosis must be confirmed by demonstrating CFTR dysfunction. The committee also recommends that the latest classifications identified in the Clinical and Functional Translation of CFTR project [http://www.cftr2.org/index.php] should be used to aid with CF diagnosis. Finally, to avoid delays in treatment, we provide guidelines for presumptive diagnoses and recommend how to determine the age of diagnosis

VAST: An ASKAP Survey for Variables and Slow Transients

The Australian Square Kilometre Array Pathfinder (ASKAP) will give us an unprecedented opportunity to investigate the transient sky at radio wavelengths. In this paper we present VAST, an ASKAP survey for Variables and Slow Transients. VAST will exploit the wide-field survey capabilities of ASKAP to enable the discovery and investigation of variable and transient phenomena from the local to the cosmological, including flare stars, intermittent pulsars, X-ray binaries, magnetars, extreme scattering events, interstellar scintillation, radio supernovae and orphan afterglows of gamma ray bursts. In addition, it will allow us to probe unexplored regions of parameter space where new classes of transient sources may be detected. In this paper we review the known radio transient and variable populations and the current results from blind radio surveys. We outline a comprehensive program based on a multi-tiered survey strategy to characterise the radio transient sky through detection and monitoring of transient and variable sources on the ASKAP imaging timescales of five seconds and greater. We also present an analysis of the expected source populations that we will be able to detect with VAST.Comment: 29 pages, 8 figures. Submitted for publication in Pub. Astron. Soc. Australi

DNA methylation-based classification of central nervous system tumours.

Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-with substantial inter-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods, resulting in a change of diagnosis in up to 12% of prospective cases. For broader accessibility, we have designed a free online classifier tool, the use of which does not require any additional onsite data processing. Our results provide a blueprint for the generation of machine-learning-based tumour classifiers across other cancer entities, with the potential to fundamentally transform tumour pathology

Order recall in verbal short-term memory: The role of semantic networks

In their recent article, Acheson, MacDonald, and Postle (Journal of Experimental Psychology: Learning, Memory, and Cognition 37:44-59, 2011) made an important but controversial suggestion: They hypothesized that (a) semantic information has an effect on order information in short-term memory (STM) and (b) order recall in STM is based on the level of activation of items within the relevant lexico-semantic long-term memory (LTM) network. However, verbal STM research has typically led to the conclusion that factors such as semantic category have a large effect on the number of correctly recalled items, but little or no impact on order recall (Poirier & Saint-Aubin, Quarterly Journal of Experimental Psychology 48A:384-404, 1995; Saint-Aubin, Ouellette, & Poirier, Psychonomic Bulletin & Review 12:171-177, 2005; Tse, Memory 17:874-891, 2009). Moreover, most formal models of short-term order memory currently suggest a separate mechanism for order coding-that is, one that is separate from item representation and not associated with LTM lexico-semantic networks. Both of the experiments reported here tested the predictions that we derived from Acheson et al. The findings show that, as predicted, manipulations aiming to affect the activation of item representations significantly impacted order memory

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes