Analisis Potensi dan Arahan Strategi Kebijakan Pengembangan Desa Ekowisata di Kecamatan Bumiaji Kota Batu

Kota Batu merupakan salah satu daerah otonom di Provinsi Jawa Timur yang mengandalkan sektor pariwisata untuk meningkatkan pendapatan asli daerah (PAD). Pengembangan pariwisata lebih mengarah pada objek wisata artifisial atau buatan yang dibangun oleh investor namun menimbulkan permasalahan lingkungan. Perlu alternatif lain pengembangan pariwisata yaitu obyek wisata yang mampu menekan dampak kerusakan lingkungan sekaligus meningkatkan peran masyarakat lokal dan kesejahteraannya yaitu pengembangan Desa Ekowisata berbasis Community Based Ecotourism (CBE). Penelitian ini bertujuan untuk melakukan penilaian potensi wisata dan obyek daya tarik wisata (ODTW) di desa desa wisata, menganalisis kesiapan terhadap pengembangan desa ekowisata, menganalisis desa wisata yang paling optimal untuk pengembangan desa ekowisata dan menentukan arahan strategi kebijakan pengembangan desa ekowisata di Kecamatan Bumiaji Kota Batu. Penelitian ini merupakan penelitian deskriptif. Pengumpulan data dengan survei primer dan sekunder. Pendekatan yang digunakan adalah Analisis potensi wisata dan obyek daya tarik wisata (ODTW), Penilaian kesiapan pengembangan Community Based Ecotourism (CBE), Analisis spasial dan Analisis SWOT. Hasil penelitian menunjukkan seluruh desa wisata di Kecamatan Bumiaji memiliki potensi wisata dan obyek daya tarik wisata (ODTW) berupa atraksi alam, sumberdaya pertanian dan budaya yang dapat lebih dikembangkan. Penilaian potensi wisata dan obyek daya tarik wisata (ODTW) menunjukkan Desa Tulungrejo dan Desa Sumberbrantas termasuk klasifikasi Sangat Baik; Analisis kesiapan terhadap pengembangan desa ekowisata berbasis masyarakat (CBE) menunjukkan Desa Tulungrejo dan Desa Bumiaji termasuk dalam klasifikasi Baik. Hasil analisis spasial menunjukkan Desa Tulungrejo merupakan desa yang paling optimal untuk pengembangan desa ekowisata di Kecamatan Bumiaji. Analisis Matrik Grand Strategy menunjukkan arahan strategi kebijakan pengembangan Desa Ekowisata di Desa Tulungrejo terletak pada kuadran 1, strategi yang digunakan bersifat agresif (SO). Kata Kunci : Kota Batu, pengembangan, potensi dan ODTW, Desa Ekowisat

Analisis Potensi dan Arahan Strategi Kebijakan Pengembangan Desa Ekowisata di Kecamatan Bumiaji Kota Batu

Kota Batu merupakan salah satu daerah otonom di Provinsi Jawa Timur yang mengandalkan sektor pariwisata untuk meningkatkan pendapatan asli daerah (PAD). Pengembangan pariwisata lebih mengarah pada objek wisata artifisial atau buatan yang dibangun oleh investor namun menimbulkan permasalahan lingkungan. Perlu alternatif lain pengembangan pariwisata yaitu obyek wisata yang mampu menekan dampak kerusakan lingkungan sekaligus meningkatkan peran masyarakat lokal dan kesejahteraannya yaitu pengembangan Desa Ekowisata berbasis Community Based Ecotourism (CBE). Penelitian ini bertujuan untuk melakukan penilaian potensi wisata dan obyek daya tarik wisata (ODTW) di desa desa wisata, menganalisis kesiapan terhadap pengembangan desa ekowisata, menganalisis desa wisata yang paling optimal untuk pengembangan desa ekowisata dan menentukan arahan strategi kebijakan pengembangan desa ekowisata di Kecamatan Bumiaji Kota Batu. Penelitian ini merupakan penelitian deskriptif. Pengumpulan data dengan survei primer dan sekunder. Pendekatan yang digunakan adalah Analisis potensi wisata dan obyek daya tarik wisata (ODTW), Penilaian kesiapan pengembangan Community Based Ecotourism (CBE), Analisis spasial dan Analisis SWOT. Hasil penelitian menunjukkan seluruh desa wisata di Kecamatan Bumiaji memiliki potensi wisata dan obyek daya tarik wisata (ODTW) berupa atraksi alam, sumberdaya pertanian dan budaya yang dapat lebih dikembangkan. Penilaian potensi wisata dan obyek daya tarik wisata (ODTW) menunjukkan Desa Tulungrejo dan Desa Sumberbrantas termasuk klasifikasi Sangat Baik; Analisis kesiapan terhadap pengembangan desa ekowisata berbasis masyarakat (CBE) menunjukkan Desa Tulungrejo dan Desa Bumiaji termasuk dalam klasifikasi Baik. Hasil analisis spasial menunjukkan Desa Tulungrejo merupakan desa yang paling optimal untuk pengembangan desa ekowisata di Kecamatan Bumiaji. Analisis Matrik Grand Strategy menunjukkan arahan strategi kebijakan pengembangan Desa Ekowisata di Desa Tulungrejo terletak pada kuadran 1, strategi yang digunakan bersifat agresif (SO). Kata Kunci : Kota Batu, pengembangan, potensi dan ODTW, Desa Ekowisat

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Comparative effects of vitamin D and vitamin C supplementations with and without endurance physical activity on metabolic syndrome patients: a randomized controlled trial

Abstract Objective Vitamin D and C levels have inverse relation with the metabolic syndrome components and they are used as antioxidant supplements during enduring metabolic activities. In the present study, we hypothesized that the intake of vitamin D and/or C with endurance physical activity might reduce the risk of metabolic syndrome. Methods A randomized control study recruited 180 participants of both genders, aged between 30 and 50 years. The participants were assigned into six groups receiving different doses of vitamin D or vitamin C with or without physical activities. Data were collected over a period of 3 months, and the results were analyzed using SPSS version 20. Results Variations in the effect of the supplements on various body variables including: Fasting plasma glucose, total cholesterol, low-density lipoprotein cholesterol and blood pressure, showed that vitamin D has more influence compared to vitamin C. However, vitamin D and C supplements do not have any effect on weight when consumers are undergoing endurance physical exercise. But vitamin C consumer group has more effect in waist circumference, triglyceride, and high-density lipoprotein, as compared to vitamin D consumer group. Conclusion We conclude that, consumption of vitamin D or vitamin C supplements may improves the life of metabolic syndrome patients. However, the combination of physical activities and vitamin supplements maximize the effect, and this combination should be recommended. Trial registration WHO-ICTRP IRCT20161110030823N2. Registered 01 February 2018. http://apps.who.int/trialsearch/Trial2.aspx?TrialID=IRCT20161110030823N