Волнения в эмигрантском корпусе Конде на русской службе в 1798 г. (по материалам РГАДА)

Between 1797 and 1798, the Prince of Condé’s French Military Corps entered the Russian army and was quartered on the territory of Volyn Region (Ukraine) in the winter of 1798. Later that spring the Prince began to introduce Russian military statutes and rules of military service in his Corps, and reorganized its military units. In response to the Prince’s actions, the French officers of the Corps started expressing discontent and protest, and the soldiers deserted on a massive scale.One of the forms of non-violent protest of the nobility against the new order of military service was personal correspondence that was sent through unofficial channels. Two of the Corps’ junior officers, de Beaumanoir and de Closets, were arrested for their daring correspondence with their relatives and friends in Austria, England and the German states. It was Emperor Paul I that personally decided upon the punishment of the rebellious aristocrats. Initially, both the Frenchmen were pardoned by the Emperor, but after some time they were demoted and exiled to Tobolsk.The article demonstrates that unrest and protest were very common in the Corps of Condé in Russia, as the officers were not prepared for the military service in the country, and were critical of the Russian reality and the military orders under Emperor Paul I. Between April and June, 1798, the military units of the Corps of Prince Condé were on the verge of open disobedience to his commands.В 1797–1798 г. французский эмигрантский корпус принца Конде перешел на русскую военную службу и зимой 1798 г. был расквартирован на Волыни. Весной принц Конде начал вводить в своем корпусе русский военный устав и правила военной службы, провел реорганизацию воинских частей своего корпуса. В ответ на действия принца французские офицеры корпуса начали проявлять недовольство и протест, солдаты массово дезертировали. Одной из форм ненасильственного протеста дворянства против новых порядков военной службы являлась личная переписка, которую отправляли по неофициальным каналам. Двое из младших офицеров корпуса, де Бомануар и де Клозе, были арестованы за «дерзкую» переписку с родственниками и друзьями в Австрии, Англии и германских землях. Вопрос о наказании аристократов-бунтовщиков решался лично императором Павлом I. Вначале оба француза были помилованы императором, но спустя некоторое время они были понижены в звании и сосланы в Тобольск.В статье показано, что среди офицеров корпуса Конде в России были широко распространены протестные настроения, офицеры не были подготовлены к военной службе в России, критически оценивали российскую действительность, а также павловские военные порядки. В апреле-июне 1798 г. военные части корпуса принца Конде находились на грани неповиновения командующему

Dynamic Acoustic Unit Augmentation With BPE-Dropout for Low-Resource End-to-End Speech Recognition

With the rapid development of speech assistants, adapting server-intended automatic speech recognition (ASR) solutions to a direct device has become crucial. Researchers and industry prefer to use end-to-end ASR systems for on-device speech recognition tasks. This is because end-to-end systems can be made resource-efficient while maintaining a higher quality compared to hybrid systems. However, building end-to-end models requires a significant amount of speech data. Another challenging task associated with speech assistants is personalization, which mainly lies in handling out-of-vocabulary (OOV) words. In this work, we consider building an effective end-to-end ASR system in low-resource setups with a high OOV rate, embodied in Babel Turkish and Babel Georgian tasks. To address the aforementioned problems, we propose a method of dynamic acoustic unit augmentation based on the BPE-dropout technique. It non-deterministically tokenizes utterances to extend the token's contexts and to regularize their distribution for the model's recognition of unseen words. It also reduces the need for optimal subword vocabulary size search. The technique provides a steady improvement in regular and personalized (OOV-oriented) speech recognition tasks (at least 6% relative WER and 25% relative F-score) at no additional computational cost. Owing to the use of BPE-dropout, our monolingual Turkish Conformer established a competitive result with 22.2% character error rate (CER) and 38.9% word error rate (WER), which is close to the best published multilingual system.Comment: 16 pages, 7 figure

Age-dependent effect of Alzheimer’s risk variant of CLU on EEG alpha rhythm in non-demented adults

Polymorphism in the genomic region harboring the CLU gene (rs11136000) has been associated with the risk for Alzheimer’s disease (AD). CLU C allele is assumed to confer risk for AD and the allele T may have a protective effect. We investigated the influence of the AD-associated CLU genotype on a common neurophysiological trait of brain activity (resting-state alpha-rhythm activity) in non-demented adults and elucidated whether this influence is modified over the course of aging. We examined quantitative electroencephalography (EEG) in a cohort of non-demented individuals (age range 20–80) divided into young (age range 20–50) and old (age range 51–80) cohorts and stratified by CLU polymorphism. To rule out the effect of the apolipoprotein E (ApoE) genotype on EEG characteristics, only subjects without the ApoE ε4 allele were included in the study. The homozygous presence of the AD risk variant CLU CC in non-demented subjects was associated with an increase of alpha3 absolute power. Moreover, the influence of CLU genotype on alpha3 was found to be higher in the subjects older than 50 years of age. The study also showed age-dependent alterations of alpha topographic distribution that occur independently of the CLU genotype. The increase of upper alpha power has been associated with hippocampal atrophy in patients with mild cognitive impairment (Moretti etal., 2012a). In our study, the CLU CC-dependent increase in upper alpha rhythm, particularly enhanced in elderly non-demented individuals, may imply that the genotype is related to preclinical dysregulation of hippocampal neurophysiology in aging and that this factor may contribute to the pathogenesis of AD

New words in human mutagenesis

<p>Abstract</p> <p>Background</p> <p>The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C > T) mutations in CpG (CG) dinucleotides. The molecular mechanisms underlying this bias are important factors in human genome evolution and cancer development. The discovery of other nucleotide contexts that have profound effects on substitution rates can improve our understanding of how mutations are acquired, and why mutation hotspots exist.</p> <p>Results</p> <p>We compared rates of inherited mutations in 1-4 bp nucleotide contexts using reconstructed ancestral states of human single nucleotide polymorphisms (SNPs) from intergenic regions. Chimp and orangutan genomic sequences were used as outgroups. We uncovered 3.5 and 3.3-fold excesses of T > C mutations in the second position of ATTG and ATAG words, respectively, and a 3.4-fold excess of A > C mutations in the first position of the ACAA word.</p> <p>Conclusions</p> <p>Although all the observed biases are less pronounced than the 5.1-fold excess of C > T mutations in CG dinucleotides, the three 4 bp mutation contexts mentioned above (and their complementary contexts) are well distinguished from all other mutation contexts. This provides a challenge to discover the underlying mechanisms responsible for the observed excesses of mutations.</p

Target-Speaker Voice Activity Detection: a Novel Approach for Multi-Speaker Diarization in a Dinner Party Scenario

Speaker diarization for real-life scenarios is an extremely challenging problem. Widely used clustering-based diarization approaches perform rather poorly in such conditions, mainly due to the limited ability to handle overlapping speech. We propose a novel Target-Speaker Voice Activity Detection (TS-VAD) approach, which directly predicts an activity of each speaker on each time frame. TS-VAD model takes conventional speech features (e.g., MFCC) along with i-vectors for each speaker as inputs. A set of binary classification output layers produces activities of each speaker. I-vectors can be estimated iteratively, starting with a strong clustering-based diarization. We also extend the TS-VAD approach to the multi-microphone case using a simple attention mechanism on top of hidden representations extracted from the single-channel TS-VAD model. Moreover, post-processing strategies for the predicted speaker activity probabilities are investigated. Experiments on the CHiME-6 unsegmented data show that TS-VAD achieves state-of-the-art results outperforming the baseline x-vector-based system by more than 30% Diarization Error Rate (DER) abs.Comment: Accepted to Interspeech 202

Investigation of the heavy nuclei fission with anomalously high values of the fission fragments total kinetic energy

Binary fission of 232Th and 238U induced by fast neutrons were under intent investigation in the IPPE during recent years. These measurements were performed with a twin ionization chamber with Frisch grids. Signals from the detector were digitized for further processing with a specially developed software. It results in information of kinetic energies, masses, directions and Bragg curves of registered fission fragments. Total statistics of a few million fission events were collected during each experiment. It was discovered that for several combinations of fission fragment masses their total kinetic energy was very close to total free energy of the fissioning system. The probability of such fission events for the fast neutron induced fission was found to be much higher than for spontaneous fission of 252Cf and thermal neutron induced fission of 235U. For experiments with 238U target the energy of incident neutrons were 5 MeV and 6.5 MeV. Close analysis of dependence of fission fragment distribution on compound nucleus excitation energy gave us some explanation of the phenomenon. It could be a process in highly excited compound nucleus which leads the fissioning system from the scission point into the fusion valley with high probability

Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV

The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009 and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncertainty for single charged and neutral particles to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3% for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table, submitted to European Physical Journal

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters