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8 research outputs found

The impact of childhood atopic dermatitis on quality of life of the paediatric population

Author: Abdulaziz A Abu Alnasr
Ahad S Alharthi
Ali A Alraddadi
Awadh M Alamri
Randa R Khafaji
Waad I Abulhamayel
Publication venue
Publication date: 30/10/2020
Field of study

BackgroundAtopic Dermatitis (AD) is a chronic skin condition characterized by pruritis which presents with xerosis, lichenification, and the eruption of eczematous lesions.AimsTo measure the quality of life in the paediatric population with atopic dermatitis at King Abdulaziz Medical City in Jeddah, Saudi Arabia.Methods The assessment tool utilized was the Infants' Dermatitis Quality of Life Index (IDQOL) questionnaire which is validated and available in Arabic. The sample size is 80 participants. Demographics, history of atopy, current treatment, and the percentage of body involved were described as frequencies. Chi-square test was performed to determine if there was a significant difference between gender, age group and the presence of other atopic disease in comparison to percentages of body involved. The analysis of the questionnaire’s items was done by One-way ANOVA to determine where significant impact on quality of life was present.Results There was a significant difference in overall IDQOL score between patient who had asthma with AD and those who did not (p=0.016). Significantly, the higher the percentage of body area affected by AD, the higher IDQOL score (p < 0.0001). No significant difference was identified for the chi-square test. Among questionnaire’s items sleep disturbance was affected the most among patients in relation to increase in distribution of disease along the body (p < 0.0001).ConclusionThe study concluded that the IDQoL among paediatric population with Atopic Dermatitis was significantly impaired, and it showed that the disease severity was proportionally related to the impairment of patients’ quality of life. Therefore, we highly recommend further studies in the same field to be able to generalize the results in the Saudi paediatric population

Australasian Medical Journal

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
Ahn J. H.
Aiken T.
Aime A.
Ajlan A.
Akalin M.
Akaydin E.
Akeel N.
Akgor U.
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Akhter Rahman M. M.
Akilli H.
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Akkour K.
Akmenkalne L.
Al Abdallah M.
Al Awwad S.
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Yuksel E.
Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Institutional Research Information System University of Turin

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
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Abad-Motos A.
Abate E.
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Aboelkassem Ibrahim A.
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Waqar S. H.
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Zakaria Z.
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Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Comparison of Different Antiviral Regimens in the Treatment of Patients with Severe COVID-19: A Retrospective Cohort

Author: Afaf S. Osman
Afrah A. Alharthi
Ahad A. Alnemari
Ahmed N. Alghamdi
Ahmed S. Abdel-Moneim
Amjad A. Alwagdani
Dalia Y. Kadry
Mohammad E. M. Mahfouz
Mubarak R. Al Yami
Nada M. Alsalmi
Razan A. Almakki
Reem K. Alghamdi
Publication venue: 'MDPI AG'
Publication date: 29/01/2023
Field of study

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes respiratory disorders, with disease severity ranging from asymptomatic to critical manifestations. The current retrospective study compared the efficacies of different antiviral regimens used in patients suffering from severe COVID-19 disease from 19 January 2020 to December 2021 in a single center in Saudi Arabia. In total, 188 patients were enrolled in the current study, including 158 patients treated with different antiviral regimens, and 30 who did not receive any antiviral treatment. Different antiviral regimens, including favipiravir, remdesivir, oseltamivir, favipiravir/remdesivir, and favipiravir/oseltamivir were adopted. The effects of using different antivirals and antibiotics on the survival rate were evaluated, as well as the presence of comorbidities. Among all severely affected patients, 39/188 (20.7%) survived. Both age and comorbidities, including diabetes and hypertension, were significantly correlated with high case fatality following SARS-CoV-2 infection. Remdesivir alone and the combination of favipiravir and remdesivir increased the survival rate. Surprisingly, both imipenem and linezolid helped in the deterioration of disease outcome in the patients. A negative correlation was detected between increased mortality and the use of favipiravir and the use of either imipenem or linezolid. Among the compared antiviral regimens used in the treatment of severe COVID-19, remdesivir was found to be an effective antiviral that reduces COVID-19 case fatality. Antibiotic treatment using imipenem and/or linezolid should be carefully re-evaluated

Multidisciplinary Digital Publishing Institute

Comparison of Different Antiviral Regimens in the Treatment of Patients with Severe COVID-19: A Retrospective Cohort

Author: Afaf S. Osman
Afrah A. Alharthi
Ahad A. Alnemari
Ahmed N. Alghamdi
Ahmed S. Abdel-Moneim
Amjad A. Alwagdani
Dalia Y. Kadry
Mohammad E. M. Mahfouz
Mubarak R. Al Yami
Nada M. Alsalmi
Razan A. Almakki
Reem K. Alghamdi
Publication venue: MDPI AG
Publication date: 01/01/2023
Field of study

Directory of Open Access Journals

Delaying surgery for patients with a previous SARS-CoV-2 infection

Author: A A Ali Karar
A A Kerawala
A A Marra
A Abad Gurumeta
A Abad-Motos
A Abdelmajeed
A Abdelrahman
A Abdelsamed
A Abdulkareem
A Aboelkassem Ibrahim
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Arda Isik
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J Á González García
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James C Glasbey
James C Glasbey
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Á De la Hoz Rodríguez
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É Ryan
Ž Grubač
А Камалов
Publication venue: 'Wiley'
Publication date: 01/01/2020
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Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.

Author: Aawsaj Y
Abad Gurumeta A
Abad-Motos A
Abate E
Abatini C
Abbadessa F
Abbas AM
Abbassi-Ghadi N
Abbott D
Abbott T
Abbott TEF
Abd Elazeem HAS
Abdalla M
Abdallah M
Abdelaal SA
Abdeldayem H
Abdelkarem MM
Abdelkarim M
Abdelmajeed A
Abdelrahman A
Abdelrahman S
Abdelsamed A
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Agnes A
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Ahmeidat A
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Akgor U
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Akin E
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Al Habes H
Al Maadany FS
Al Raddadi R
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Al-Habib A
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Al-Mohammad A
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Alakaloko F
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Alatar A
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Alazawi D
Albertsmeier M
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Aldecoa Ansorregui I
Alderson D
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Almeida A
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Almeida JI
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Alonso Poza A
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Alser O
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Alshammari S
Alshareea E
Alsharif F
Alshaygy I
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Althobaiti W
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Alurralde C
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Andaleeb U
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Antonopoulou MI
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Aremu I
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Athanasakis E
Athanasiou A
Athayde Nemesio R
Atherton R
Athwal R
Atici DS
Atta R
Attia D
Augestad KM
Australasian T
Avci EK
Avlund T
Awad S
Ayasra F
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Ayasra Y
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Aytac E
Ayub B
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Azamat IF
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Azzam AY
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Baca B
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Baena Sanfeliu E
Baeza Pintado N
Bagraith K
Baia C
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Bajomo O
Baker A
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Balasubramanian I
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Balik E
Ballabio M
Ballal M
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Baloyiannis I
Bambina F
Ban VS
Bandara GBK
Bandiera A
Bandovas JP
Banerjee A
Bankhead-Kendall BK
Bankhead-Kendall BK
Banky B
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Baptista VH
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Becerra Garcia FC
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Belcher E
Belia F
Belkhadir ZH
Bellacci A
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Belluco C
Beltramini GA
Beltran de Heredia J
Belvedere A
Benavides Buleje JA
Benkabbou A
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Benson O
Benson RA
Benson RA
Bergamini C
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Bernante P
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Bezede C
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Bhangu AA
Bhangu AA
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Bhatti MI
Biala M
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Bianchini M
Bianco F
Bianco F
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Biel JR
Bigay K
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Bille A
Bin Nasser A
Bin Traiki T
Biondi A
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Blanco-Colino R
Blanco-Colino R
Blas Laina JL
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Bravo Infante R
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Brito da Silva F
Brixton G
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Bromage S
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Brunelli A
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Buarque IL
Budacan A
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Bueno Canones AD
Buerba GA
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Burahee A
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Cabezudo Noguera SF
Cadenelli P
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Cagigal Ortega EP
Cagigas Fernandez C
Cahill J
Caiado A
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Caina Ruiz R
Caird S
Cairncross L
Caja Vivancos P
Cakmak G
Calabro M
Callanan D
Calvo Espino P
Camacho C
Camillo' A
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Campagnaro T
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Campbell W
Campisi G
Canas-Martinez A
Candiani M
Candotti G
Canhoto C
Cano A
Cano-Valderrama O
Canonico G
Canotilho R
Cantalejo Diaz M
Cao H
Capelli P
Capezzuoli L
Capitan-Morales L
Capizzi V
Capoglu R
Capolupo GT
Carabias A
Caram EL
Carannante F
Carcoforo P
Cardoso N
Cardoso P
Caricato M
Carrano FM
Carrasco Prats M
Carroll P
Carta AG
Carter J
Caruana EJ
Caruana EJ
Caruana EJ
Caruso J
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Cassinotti E
Castano-Leon AM
Castillejos-Molina RA
Catala Bauset JC
Catarzi L
Cato LD
Cavaleiro S
Cavalle Busquets P
Cayetano Paniagua L
Cazador Labat M
Cecchini L
Cecconello I
Cecire J
Celebi F
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Cellerino P
Cenciarelli S
Ceranic M
Ceretti PA
Cervellera M
Cervera I
Ceyhan GO
Chaar M
Chai AKW
Chakib O
Chakrabortee S
Challacombe B
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Chan C
Chan CW
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Chandock A
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Chardalias L
Charlton G
Chase T
Chatzikomnitsa P
Chaudhry D
Chaudhury M
Chavarrias N
Chebaro A
Checcucci C
Chen L
Chen L
Chen S
Chern H
Chessa A
Cheung LK
Chevallay M
Chew D
Chia Z
Chiappini A
Chiarella V
Chiarugi M
Chidambaram S
Chiesa-Estomba CM
Chiozza M
Chitul A
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Choi D
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Chong L
Choolani Bhojwani E
Choong P
Chopra S
Choudhry A
Choudhury J
Chouillard E
Chowdhry MF
Chowdhury A
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Christensen P
Christensen P
Christidis P
Christoforidis D
Christou C
Chrysos E
Chu F
Chumbinho B
Chung E
Cianflocca D
Ciccarone F
Cicerchia PM
Cimenoglu B
Cintas Catena J
Cioffi SPB
Ciofic E
Cipriani R
Cirillo B
Cirocchi N
Cisternino G
Citgez B
Citterio D
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Clifford R
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Cocozza E
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Coffey JC
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Colak E
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Colino M
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Colledan M
Collera P
Colletti G
Collins C
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Colombari RC
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Colquhoun A
Combellack T
Comini LV
Conesa A
Confalonieri M
Conlon K
Connelly T
Connolly EM
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Conti L
Conti L
Contis I
Cool P
Coonar AS
Coonar AS
Cope D
Corbellini C
Corbin S
Cordera F
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Correia de Sa T
Correia AM
Correia J
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Corte Real J
Corvera C
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Cosimelli M
Cossu ML
Costa Santos D
Costa M
Costa MJMA
Costanzi A
Costeira B
Costigan F
Cotoia A
Cotsoglou C
Cotte E
Cotter A
Cottu P
Coughlin P
Cox D
Coza I
Cozza V
Crank M
Creavin B
Cribb G
Crichton A
Cristian D
Cros B
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Cuadrado-Garcia A
Cukier M
Cullinane C
Cullivan O
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Cunha MF
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Cunningham R
Curl-Roper T
Currie A
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Cymes W
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D'Amore A
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D'Angelo G
D'Ugo D
D'Ugo S
D'Urso A
Dafnios N
Daiko H
Dainius E
Dakpe S
Daliya P
Daly A
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Daniels I
Davidson B
Davidson GH
Davies A
Davies E
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Davies RJ
Dawe N
Dawson BE
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De Andres Olabarria U
De Barros J
De Berardinis R
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De Cicco R
De Crescenzo E
De Graaff M
De Iaco P
De la Hoz Rodriguez A
De la Rosa Abaroa MA
De Lacy FB
De Miguel Ardevines MDC
De Nardi P
De Oliveira Lopez AL
De Pablo Garcia-Cuenca A
De Palma G
De Pastena M
De Simone B
De Simone V
de Solorzano Aurusa OFJ
De Sousa X
De Toma G
De Troia A
De Vincenti R
De Virgilio A
Dehal A
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Del Valle E
Delgado Fernandez J
Deligiannidis D
Delimpalta C
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Delrio P
Demetriades AK
Demir H
Demirhan R
Demyttenaere S
Denet C
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Depalma N
Derkaoui Hassani F
Derksen T
Desai A
Desai A
Desai A
Desio M
Deus AC
Devauchelle B
Devezas V
Devine M
Di Bartolomeo A
Di Bella A
Di Candido F
Di Chiara F
Di Franco G
Di Giuseppe M
Di Martino C
Di Martino M
Di Marzo F
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Di Somma A
Di Taranto G
Diamantis A
Dias B
Diaz Del Gobbo R
Diaz Pena P
Diaz Perez D
Diaz-Feijoo B
Dickson K
Dieguez B
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Diez-Valladares L
Dijan E
Dikicier E
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Dincer HA
Distler M
Divya GS
Dixon J
Djurisic I
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Domingo S
Domingues JC
Dominguez I
Dominguez-Rosado I
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Donati DM
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Donohue C
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Doyle A
Drake T
Drake TM
Drubay V
Duchalais E
Dudi-Venkata NN
Duff S
Dulgeroglu O
Dumitra S
Dumitra S
Dunderovic D
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Dunning J
Duque M
Duque-Mallen V
Duran Ballesteros M
Duran-Valles F
Durrani A
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Dwidar O
Dzamic Z
Dziakova J
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Eastmond A
Ebbehoj AL
Economopoulou P
Edmond M
Edmondson R
Edwards J
Edwards J
Edwards JG
Efthimiou M
Egan R
Egbeare D
Egbuchulem IK
Egoroff N
Eiriz Fernandez C
El Aamrani M
El Abbadi N
El Ahmadi B
El Bouazizi Y
El Ouahabi A
El-sayed I
Elawad A
Elayyan M
Elazzazy E
Elbe P
Eldaly A
Elena GDCR
ElFiky M
Elghazaly MS
Elhadi M
Elhamshary A
Elhoseiny M
Elhusseini M
Elkadi H
Elkaffas SMMM
Elkhayat H
Elliott JA
Elliott M
Ellojli I
Elmoslemany T
Elnemr M
Elqasabi MS
Elsey E
Elshaer M
Elsherbini I
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Elwatidy S
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Emile S
Emiroglu M
Emmanuel K
Emslie K
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Ensenat Nora J
Ergun S
Erol T
Escartin J
Escobar P
Escola D
ESCP ESC
Esene I
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Eskander P
Eskinazi D
Espin-Basany E
Espino Segura-Illa M
Espinosa CA
Espitalier F
Esposito A
Esposito G
Essam E
Essangri H
Estaire Gomez M
Esteban Agusti E
Esteban Sinovas O
Esteban A
Etchill E
Ethunandan M
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Evans C
Evans C
Evans J
Evans JP
Evans JP
Evans RPT
Evans S
Eveno C
Evoy D
Eweda M
Ezanno A
Fabbri N
Fabregas N
Fadzli A
Fagotti A
Fagotti A
Fahey BA
Fahim M
Fahmawee T
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Falcon GM
Fambrini M
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Fancellu A
Faria CS
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Farma J
Farnesi F
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Farre Font R
Farrell R
Farsi A
Fasanmade K
Fathi NQ
Faulkner G
Faustino A
Fayed Y
Fazenda A
Fearon N
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Federico PNS
Fehervari M
Felli E
Fenton M
Feo CF
Feo CV
Fernandes U
Fernandes V
Fernandez Bernabe P
Fernandez Camunas A
Fernandez Pablos FJ
Fernandez Rodriguez P
Fernandez M
Fernandez PV
Fernandez-Lopez A
Fernando D
Ferrari F
Ferrari M
Ferrario L
Ferraz I
Ferreira Pinto AP
Ferreira C
Ferreli F
Ferrero A
Ferrero S
Ferres A
Ferron C
Fidalgo H
Fidelis L
Figari M
Figueiredo de Barros I
Findlay L
Finnegan L
Fiore M
Fiore M
Fiore M
Fiore M
Fiori E
Fiorini A
Firat N
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Fitzgerald C
Fitzgerald JE
Fitzjohn H
Flamey N
Flavin M
Fleming C
Fleming D
Fleming J
Fletcher A
Flindall I
Flores Clotet R
Foley D
Foley E
Folli S
Fong R
Fonseca F
Fonsi GB
Fontana M
Fontana T
Foo CC
Ford S
Ford S
Ford S
Fordington S
Forouhi P
Fortuna L
Fossett R
Fotopoulou C
Fotopoulou C
Foulkes R
Fountain D
Fountain DM
Fowler A
Fowler G
Fox A
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Fragulidis G
Frampton A
Franco G
Francone E
Frankel A
Franken J
Frantzeskou K
Franza M
Fraser L
Fraser S
Frasson M
Frati A
Frattaruolo C
Fregatti P
Freitas A
Frena A
Freyschlag C
Freyschlag C
Freystaetter K
Frias L
Frio F
Frisoni T
Fritzmann J
Frongia F
Fruscio R
Fu H
Fujiwara K
Fuks D
Fulginiti SF
Fullmer T
Furbetta N
Fusai G
Fusetti S
Fuson A
Futaba K
Futaba K
Fuwa O
Gabre-Kidan A
Gabre-Kidan A
Gacic S
Gagliano A
Gagliardi F
Gahunia S
Gaino F
Gainza A
Gajjar K
Gala T
Galindo Jara P
Galis B
Gallagher K
Gallagher T
Galliamov E
Gallo G
Gallo G
Gallo G
Galun D
Galvao D
Gambacciani C
Gan C
Gananadha S
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Gani J
Ganly I
Ganly I
Garberini DMA
Garces Garcia R
Garces-Albir M
Garcia Alonso M
Garcia Egea J
Garcia Escudero D
Garcia Gutierrez JJ
Garcia Perez D
Garcia Perez JM
Garcia Pineda V
Garcia Porcel VJ
Garcia Rico E
Garcia Romero E
Garcia Santos EP
Garcia Senorans PM
Garcia Septiem J
Garcia Soria V
Garcia Villayzan JE
Garcia JS
Garcia PM
Garcia-Conde M
Garcia-Loarte Gomez E
Garcia-Moreno Nisa F
Garcia-Quijada J
Garcia-Sancho Tellez L
Garfinkle R
Garmanova T
Garmanova T
Garrett W
Garrido R
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Gascon Ferrer I
Gash K
Gaskill C
Gasparini G
Gata V
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Gattolin A
Gaunt A
Gauri N
Gavalda Pellice MGP
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Gegundez Simon A
Gelarda E
Gemmell C
Gemmill E
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Gennaro M
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Georgiades F
Geraghty J
Gerchunoff JI
Geretto P
Ghallab I
Ghaly G
Ghamgh R
Ghanbari A
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Ghannam A
Ghazali N
Ghebre R
Ghedan S
Ghitulescu G
Ghosh D
Ghufoor K
Ghunaim M
Giacometti M
Giaglaras A
Gialamas E
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Giblin A
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Gigliotti J
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Gil CG
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Ginesu GC
Ginghina O
Giralt Lopez de Sagredo J
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Giray B
Giuffrida MC
Giugliano M
Giuliani G
Gkekas I
Gklavas A
Gkrinia E
Glasbey JC
Glasbey JC
Glasbey JC
Glasbey JC
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Glencer A
GlobalPaedSurg
GlobalSurg
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Gomes da Costa A
Gomes GMA
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Gomez Diaz CJ
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Gomez Latorre L
Gomez Portugal PE
Gomez Ruiz M
Gomez Sanz T
Gomez P
Gomez-Pedraza A
Gomez-Rosado J
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Publication venue: Br J Surg
Publication date: 11/11/2020
Field of study

BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; P = 0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas

Ezid

Crossref

AIR Universita degli studi di Milano

UCL Discovery

eScholarship - University of California

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Apollo (Cambridge)

Bern Open Repository and Information System (BORIS)

Queen Mary Research Online

White Rose Research Online

Archivio istituzionale della ricerca - Università di Palermo