Dynamic Behavior and Performance of Different Types of Multi-Effect Desalination Plants

Water and energy are two of the most vital resources for the socio-economic development and sustenance of humanity on earth. Desalination of seawater has been practiced for some decades and is a well-established means of water supply. However, this process consumes large amounts of energy and the global energy supply is also faced with some challenges. In this research, multi-effect desalination (MED) has been selected due to lower cost, lower operating temperature and efficient in terms of primary energy and electricity consumption compared to other thermal desalination systems. The motivation for this research is to address thermo-economics and dynamic behavior of different MED feed configurations with/without vapor compression (VC). A new formulation for the steady-state models was developed to simulate different MED systems. Adding a thermal vapor compressor (TVC) or mechanical vapor compression (MVC) unit to the MED system is also studied to show the advantage of this type of integration. For MED-TVC systems, results indicate that the parallel cross feed (PCF) configuration has better performance characteristics than other configurations. A similar study of MED-MVC systems indicates that the PCF and forward feed (FF) configurations require less work to achieve equal distillate production. Reducing the steam temperature supplied by the MVC unit leads to an increase in second law efficiency and a decrease in specific power consumption (SPC) and total water price. Following the fact that the MED may be exposed to fluctuations (disturbances) in input parameters during operation. Therefore, there is a requirement to analyze their transient behavior. In the current study, the dynamic model is developed based on solving the basic conservation equations of mass, energy, and salt. In the case of heat source disturbance, MED plants operating in the backward feed (BF) may be exposed to shut down due to flooding in the first effect. For all applied disturbances, the change in the brine level is the slowest compared to the changes in vapor temperature, and brine and vapor flow rates. For MED-TVC, it is recommended to limit the seawater cooling flow rate reduction to under 12% of the steady-state value to avoid dryout in the evaporators. A reduction in the motive steam flow rate and cooling seawater temperature of more than 20% and 35% of steady-state values, respectively, may lead to flooding in evaporators and plant shutdown. Simultaneous combinations of two different disturbances with opposing effects have only a modest effect on plant operation and they can be used to control and mitigate the flooding/drying effects caused by the disturbances. For the MED-MVC, the compressor work reduction could lead to plant shutdown, while a reduction in the seawater temperature will lead to a reduction in plant production and an increase in SPC

Immunological characterization of diphtheria toxin recovered from Corynebacterium pseudotuberculosis

AbstractDiphtheria toxin (DT) is a potent toxin produced by the so-called diphtheria group which includes Corynebacterium diphtheriae (C. diphtheriae), Corynebacterium ulcerans (C. ulcerans), and Corynebacterium pseudotuberculosis (C. pseudotuberculosis). The present investigation is aimed to study in detail the production of DT by C. pseudotuberculosis. Twenty isolates were obtained from sheep diseased with caseous lymphadenitis (CLA) and twenty-six isolates were obtained from 26 buffaloes diseased with oedematous skin disease (OSD). All isolates were identified by standard microbiological and DT production was assayed serologically by modified Elek test and immunoblotting. All sheep isolates were nitrate negative, failed to hydrolyze starch and could not produce DT, while all buffalo isolates (biotype II) revealed positive results and a specific band of 62kDa, specific to DT, was resulted in all concentrated cell fractions (CF), but was absent from non-toxigenic biotype I isolates. At the same time, another band of 31kDa specific to the PLD gene was obtained with all isolates of biotype I and II. Moreover, all isolates showed positive synergistic hemolytic activity and antagonistic hemolysis with β-hemolytic Staphylococci. The obtained results also indicated that C. pseudotuberculosis could be classified into two strains; non-toxigenic biotype I strain, which failed to produce DT as well as being negative to nitrate and starch hydrolysis, and toxigenic biotype II strain, which can reduce nitrate, hydrolyze starch as well as produce DT

Using InSAR coherence for investigating the interplay of fluvial and aeolian features in arid lands: implications for groundwater potential in Egypt

Despite the fact that the Sahara is considered the most arid region on Earth, it has witnessed prolonged fluvial and aeolian depositional history, and might harbor substantial fresh groundwater resources. Its ancient fluvial surfaces are, however, often concealed by aeolian deposits, inhibiting the discovery and mapping of potential groundwater recharge areas. However, recent advances in synthetic aperture radar (SAR) imaging offer a novel approach for detecting partially hidden and dynamic landscape features. Interferometry SAR coherence change detection (CCD) is a fairly recent technique that allows the mapping of very slight surface changes between multidate SAR images. Thus, this work explores the use of the CCD method to investigate the fluvial and aeolian morphodynamics along two paleochannels in Egypt. The results show that during wetter climates, runoff caused the erosion of solid rocks and the rounding of sand-sized grains, which were subsequently deposited in depressions further downstream. As an alternating dry climate prevailed, the sand deposits were reshaped into migrating linear dunes. These highly dynamic features are depicted on the CCD image with very low coherence values close to 0 (high change), while the deposits within the associated ephemeral wadis show low to moderate coherence values ranging from 0.2 to 0.4 (high to moderate change), and the country rocks show a relative absence of change with high coherence values close to 1. These linear dunes crossed their parent’s stream courses and dammed the runoff to form lakes during rainy seasons. Part of the dammed surface water would have infiltrated the ground to recharge the permeable wadi deposits. The alternation of fluvial and aeolian depositional environments produced unique hydromorphometrically trapped lakes that are very rare in arid regions, but of great interest because of their significance to groundwater recharge

EPIDEMIC OF RIFT VALLEY FEVER IN SUDAN, GEZIRA, 2007; GEZIRA EXPERIENCE

In the last 3 months of 2007, an acute episode of an ill-defined severe febrile illness presented to Medani hospital isolation words, with severe hemorrhagic manifestations. This initially did not harbor any attention as other possibilities were thought of like severe malaria , septicaemia but by the end of the same week the number of patients increased dramatically and the suspicion was put and the whole case was addressed officially in an epidemical paradigm. This study was conducted in Wad Medani Teaching Hospital. From the beginning of 41st week of the year 2007, the Gezira state in Sudan was tremendously affected by an epidemic of Rift valley fever as declared by the WHO authorities (11).all the districts of the estate were involved with a total number of patients was around 392. During the period of epidemic of RVF, (week 41.2007 - up to the 1st week of January 2008) total number of patients admitted were about 392 and total number of patients died were 158 patients .The main presenting symptoms were fever, epistaxsis, haematemesis and vaginal bleeding, and the main complication was acute renal failure and death

Mapping the groundwater potentiality of West Qena area, Egypt, using integrated remote sensing and hydro-geophysical techniques

The integrated use of remote sensing imagery and hydro-geophysical field surveys is a well-established approach to map the hydrogeological framework, and thus explore and evaluate the groundwater potentiality of desert lands, where groundwater is considered as the main source of freshwater. This study uses such integrated approach to map the groundwater potentiality of the desert alluvial floodplain of the Nile Valley west of Qena, Egypt, as alternative water source to the River Nile. Typically ground gradient, faults and their stress field, lateral variation of rock permeability, drainage patterns, watersheds, rainfall, lithology, and soil types are the main factors believed to affect the groundwater recharge and storage from the infiltration of present-time and paleo-runoff. Following this generally accepted approach, different remote sensing data sets (SRTM DEM, Landsat-8, ALOS/PALSAR-1, Sentinel-1, and TRMM) as well as auxiliary maps (geological and soil maps) were used to identify and map these factors and prepare thematic maps portraying the different influences they exert on the groundwater recharge. These thematic maps were overlaid and integrated using weights in a GIS framework to generate the groundwater potentiality map which categorizes the different recharge capabilities into five zones. Moreover, the aeromagnetic data were processed to map the deep-seated structures and estimate the depth to basement rocks that may control the groundwater occurrence. In addition, the vertical electrical sounding (VES) measurements were applied and calibrated with the available borehole data to delineate the subsurface geological and hydrogeological setting as well as the groundwater aquifers. Different geoelectric cross-sections and hydro-geophysical maps were constructed using the borehole information and VES interpretation results to show the lateral extension of the different lithological units, groundwater-bearing zones, water table, and the saturated thickness of the aquifer. The GIS model and geophysical results show that the southwest part of Nag’a Hammadi-El-Ghoneimia stretch has very high recharge and storage potentiality and is characterized by the presence of two groundwater-bearing zones. The shallow groundwater aquifer is located at a depth of 30 m with a saturation thickness of more than 43 m. However, there are NW–SE faults crossing the study area and most likely serve as recharge conduits by connecting the shallow aquifer with the deeper ones. Such aquifers connection has been confirmed by investigating the chemical and isotopic composition of their groundwater.Published versio

Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis

Introduction: Isoproterenol (ISO) is regarded as an adrenergic non-selective β agonist. It regulates myocardial contractility and may cause damage to cardiac tissues. Alchemilla vulgaris (AV) is an herbal plant that has garnered considerable attention due to its anti-inflammatory and antioxidant bioactive components. The present investigation assessed the cardioprotective potential of AV towards ISO-induced myocardial damage.Methods: Four groups of mice were utilized: control that received saline, an ISO group (85 mg/kg, S.C.), ISO + AV100, and ISO + AV200 groups (mice received 100 or 200 mg/kg AV orally along with ISO).Results and discussion: ISO induced notable cardiac damage demonstrated by clear histopathological disruption and alterations in biochemical parameters. Intriguingly, AV treatment mitigates ISO provoked oxidative stress elucidated by a substantial enhancement in superoxide dismutase (SOD) and catalase (CAT) activities and reduced glutathione (GSH) content, as well as a considerable reduction in malondialdehyde (MDA) concentrations. In addition, notable downregulation of inflammatory biomarkers (IL-1β, TNF-α, and RAGE) and the NF-κB/p65 pathway was observed in ISO-exposed animals following AV treatment. Furthermore, the pro-apoptotic marker Bax was downregulated together with autophagy markers Beclin1 and LC3 with in ISO-exposed animals when treated with AV. Pre-treatment with AV significantly alleviated ISO-induced cardiac damage in a dose related manner, possibly due to their antioxidant and anti-inflammatory properties. Interestingly, when AV was given at higher doses, a remarkable restoration of ISO-induced cardiac injury was revealed

Large-vscale hydrogen production and storage technologies: Current status and future directions

This is an accepted manuscript of an article published by Elsevier in International Journal of Hydrogen Energy on 13/11/2020, available online: https://doi.org/10.1016/j.ijhydene.2020.10.110 The accepted version of the publication may differ from the final published version.Over the past years, hydrogen has been identified as the most promising carrier of clean energy. In a world that aims to replace fossil fuels to mitigate greenhouse emissions and address other environmental concerns, hydrogen generation technologies have become a main player in the energy mix. Since hydrogen is the main working medium in fuel cells and hydrogen-based energy storage systems, integrating these systems with other renewable energy systems is becoming very feasible. For example, the coupling of wind or solar systems hydrogen fuel cells as secondary energy sources is proven to enhance grid stability and secure the reliable energy supply for all times. The current demand for clean energy is unprecedented, and it seems that hydrogen can meet such demand only when produced and stored in large quantities. This paper presents an overview of the main hydrogen production and storage technologies, along with their challenges. They are presented to help identify technologies that have sufficient potential for large-scale energy applications that rely on hydrogen. Producing hydrogen from water and fossil fuels and storing it in underground formations are the best large-scale production and storage technologies. However, the local conditions of a specific region play a key role in determining the most suited production and storage methods, and there might be a need to combine multiple strategies together to allow a significant large-scale production and storage of hydrogen.Published versio

Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.

BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112