1,890 research outputs found
La compétence organisationnelle chez Cuisines Laurier
Les entreprises sâinscrivent dans un espace-temps caractĂ©risĂ© par une concurrence qui croĂźt en Ă©tendue et en vitesse, ce qui exacerbe la pression sur les dirigeants et les employĂ©s. Pour assurer la persistance de leur entreprise, ces derniers doivent Ă©lever sans cesse sa capacitĂ© de rĂ©ussir, sa compĂ©tence organisationnelle. Les chercheurs qui sâintĂ©ressent au monde des entreprises nâont pas manquĂ© de le noter et ont Ă©laborĂ© diffĂ©rentes conceptions de cette compĂ©tence ou de phĂ©nomĂšnes qui lui sont associĂ©s, comme lâapprentissage organisationnel, les capacitĂ©s organisationnelles ou les capacitĂ©s dynamiques dâune organisation. Comment les membres dâune organisation sây prennent-ils pour en assurer la compĂ©tence? VoilĂ la question Ă laquelle je tente de rĂ©pondre Ă mon tour. Je fais dâabord un examen critique de travaux liĂ©s Ă cette question, puis je propose un cadre conceptuel prenant appui en partie sur la thĂ©orie de la structuration et sur les concepts de communautĂ© de praticiens et dâapprentissage expĂ©rientiel. Suit un cadre opĂ©ratoire dans lequel je justifie le choix dâune Ă©tude de cas, je caractĂ©rise lâentreprise Ă©tudiĂ©e, une manufacture dâarmoires de cuisine et de vanitĂ©s de salle de bain, et jâindique comment je mây suis pris pour rĂ©colter les matĂ©riaux pendant un sĂ©jour de prĂšs de six mois dans cette entreprise, et comment jâai exploitĂ© ces matĂ©riaux. Que ce soit dans leurs activitĂ©s de tous les jours ou face Ă des situations nouvelles, les dirigeants et employĂ©s de lâentreprise, parfois de façon individuelle mais plus souvent de façon collective, mobilisent diffĂ©rentes propriĂ©tĂ©s structurelles de lâentreprise et, chaque fois quâils le jugent utile, nâhĂ©sitent pas Ă modifier ou Ă abandonner certaines dâentre elles, ou Ă en crĂ©er de nouvelles afin dâĂ©lever leur capacitĂ© dâatteindre les objectifs quâils se fixent, notamment en ce qui a trait Ă la qualitĂ© des rapports humains, au climat de travail, au volume de production, Ă sa qualitĂ©, Ă la productivitĂ© ou au rendement financier. Cette entreprise rĂ©ussit en mobilisant ses membres, en favorisant lâexpĂ©rimentation, lâapprentissage et la production de connaissances nouvelles quâelle intĂšgre ensuite dans ses protocoles et ses routines, crĂ©ant un cycle qui Ă©lĂšve sans cesse son niveau de compĂ©tence.Businesses today exist in an environment characterized by endlessly expanding competition, the speed and scope of which are increasing the pressure on both managers and employees. In order to guarantee their long term existence, businesses must continually strive to improve their capacity for success and their organizational competence. Researchers interested in the business world have not failed to notice this and have elaborated different conceptions of this competence or its related phenomena such as organizational learning, organizational capabilities or the dynamic capabilities of an organization. How do the members of an organization go about ensuring the competence of their organization? This is the question I am trying to answer. First, I will make a critical examination of the existing research linked to this question. Then, I will propose a conceptual framework partly based on structuration theory and on the concepts of community of practice and experiential learning. An operational framework will follow in which I justify the choice of a case study, characterize the firm studied, a manufacturer of kitchen cabinets and bathroom vanities, indicate how I came to gather materials during a stay of close to six months in this business, and how I exploited these materials. Whether in their daily activities or when facing new situations, managers and employees of the firm, sometimes in an individual manner but most often in a collective manner, will mobilize different structural properties of the firm. When considered useful, they will not hesitate to modify or abandon any of these structural properties or create new ones in order to increase their capabilities of achieving their objectives, particularly in matters concerning human relations, the work climate, production output and quality, productivity and financial returns. This firm succeeds in mobilizing its members, in encouraging experimentation, learning and production of new knowledge which is integrated into its protocols and routines, thus creating a cycle that constantly increases its level of competence
La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia departamento del Tolima.
La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia departamento del Tolima.El reciente trabajo del Diplomado de ProfundizaciĂłn y Acompañamiento Psicosocial en Escenarios de Violencia, alcanza una serie de ocupaciones realizadas con base a las fracciones de la vida real y que en si encierran una de las problemĂĄtica que se vive en el dĂa a dĂa en nuestro paĂs y diferentes contextos transcendentales y familiares de determinadas poblaciones en los cuales se han marcado por los diferentes escenarios de violencia y de los cuales se vive la parte inhumana que ejerce las conductas por parte de grupos al margen de la ley, los representantes de este conflicto que enmarca en Colombia, estos a su vez descubran falsedades psicosociales asociadas al desplazamiento forzado y emanadas a su vez a las vĂctimas. La intenciĂłn es emprender en el ĂĄmbito psicosocial por medio de la narrativa, en donde se asemejen los procedente relacionados, con ello se puede lograr descubrir del porque las poblaciones pueden ser objeto de señalar, asociado a lo anterior descubrimos una serie de preguntas circulares, reflexivas y estratĂ©gicas, las cuales se expresan en un caso particular, considerando la problemĂĄtica desde el rol del psicĂłlogo hacia las vĂctimas, tambiĂ©n se articula desde la experiencia de foto voz donde se unen a la prĂĄctica, finalmente la como se destaca el modelos de resiliencia en un definitivo contexto de violencia.The recent work of the Diploma of Deepening and Psychosocial Accompaniment in Scenarios of Violence, reaches a series of occupations made based on the fractions of real life and that if they contain one of the problems that are lived in the day to day in our country and different transcendental and family contexts of certain populations in which they have been marked by the different scenarios of violence and from which the inhuman part that exerts the behaviors of groups outside the law, the representatives of this conflict that framed in Colombia, these in turn discover psychosocial falsehoods associated with forced displacement and in turn emanated from the victims. The intention is to undertake in the psychosocial field by means of the narrative, where the related ones are similar, with this it is possible to discover why populations can be pointed out, associated with the above we discover a series of circular, reflective questions and strategic, which are expressed in a particular case, considering the problem from the role of the psychologist to the victims, it is also articulated from the experience of photo voice where they join the practice, finally how the resilience models stand out in A definitive context of violence
A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC
Most approved vaccines against COVID-19 have to be administered in a prime/boost regimen. We engineered a novel vaccine based on a chimeric human adenovirus 5 (hAdV5) vector. The vaccine (named CoroVaxG.3) is based on three pillars: (i) high expression of Spike to enhance its immunodominance by using a potent promoter and an mRNA stabilizer; (ii) enhanced infection of muscle and dendritic cells by replacing the fiber knob domain of hAdV5 by hAdV3; (iii) use of Spike stabilized in a prefusion conformation. The transduction with CoroVaxG.3-expressing Spike (D614G) dramatically enhanced the Spike expression in human muscle cells, monocytes and dendritic cells compared to CoroVaxG.5 that expressed the native fiber knob domain. A single dose of CoroVaxG.3 induced a potent humoral immunity with a balanced Th1/Th2 ratio and potent T-cell immunity, both lasting for at least 5 months. Sera from CoroVaxG.3-vaccinated mice was able to neutralize pseudoviruses expressing B.1 (wild type D614G), B.1.117 (alpha), P.1 (gamma) and B.1.617.2 (delta) Spikes, as well as an authentic P.1 SARS-CoV-2 isolate. Neutralizing antibodies did not wane even after 5 months, making this kind of vaccine a likely candidate to enter clinical trials.Fil: LĂłpez, M. VerĂłnica. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Vinzon, Sabrina Eugenia. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Cafferata, Eduardo Gustavo Alfredo. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Nuñez, Felipe. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Soto, Ariadna Soledad. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Sanchez Lamas, Maximiliano. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Afonso, MarĂa Jimena. FundaciĂłn Instituto Leloir; ArgentinaFil: Aguilar Cortes, Diana Carolina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Rios, Gregorio David. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Maricato, Juliana T.. Universidade Federal de Sao Paulo; BrasilFil: Torres Braconi, Carla. Universidade Federal de Sao Paulo; BrasilFil: Barbosa da Silveira, Vanessa. Universidade Federal de Sao Paulo; BrasilFil: Montes de Andrade, Tatiane. Universidade Federal de Sao Paulo; BrasilFil: Carvalho de Souza Bonetti, Tatiana. Universidade Federal de Sao Paulo; BrasilFil: Ramos Janini, Luiz M.. Universidade Federal de Sao Paulo; BrasilFil: Castello GirĂŁo, Manoel J. B.. Universidade Federal de Sao Paulo; BrasilFil: Llera, Andrea Sabina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Gomez, Karina Andrea. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Instituto de Investigaciones en IngenierĂa GenĂ©tica y BiologĂa Molecular "Dr. HĂ©ctor N. Torres"; ArgentinaFil: Ortega, Hugo Hector. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Santa Fe. Instituto de Ciencias Veterinarias del Litoral. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias. Instituto de Ciencias Veterinarias del Litoral; ArgentinaFil: Berguer, Paula Mercedes. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; ArgentinaFil: Podhajcer, Osvaldo Luis. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Parque Centenario. Instituto de Investigaciones BioquĂmicas de Buenos Aires. FundaciĂłn Instituto Leloir. Instituto de Investigaciones BioquĂmicas de Buenos Aires; Argentin
The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment
The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in
operation since July 2014. This paper describes the second data release from
this phase, and the fourteenth from SDSS overall (making this, Data Release
Fourteen or DR14). This release makes public data taken by SDSS-IV in its first
two years of operation (July 2014-2016). Like all previous SDSS releases, DR14
is cumulative, including the most recent reductions and calibrations of all
data taken by SDSS since the first phase began operations in 2000. New in DR14
is the first public release of data from the extended Baryon Oscillation
Spectroscopic Survey (eBOSS); the first data from the second phase of the
Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2),
including stellar parameter estimates from an innovative data driven machine
learning algorithm known as "The Cannon"; and almost twice as many data cubes
from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous
release (N = 2812 in total). This paper describes the location and format of
the publicly available data from SDSS-IV surveys. We provide references to the
important technical papers describing how these data have been taken (both
targeting and observation details) and processed for scientific use. The SDSS
website (www.sdss.org) has been updated for this release, and provides links to
data downloads, as well as tutorials and examples of data use. SDSS-IV is
planning to continue to collect astronomical data until 2020, and will be
followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14
happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov
2017 (this is the "post-print" and "post-proofs" version; minor corrections
only from v1, and most of errors found in proofs corrected
Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19
Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe
Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies
There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR gamma:Peroxisome proliferator-activated receptor, NF kappa B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2 alpha:Elongation initiation factor 2 alpha). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT(1)R axis (AT(1)R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
Study of the decay
The decay is studied
in proton-proton collisions at a center-of-mass energy of TeV
using data corresponding to an integrated luminosity of 5
collected by the LHCb experiment. In the system, the
state observed at the BaBar and Belle experiments is
resolved into two narrower states, and ,
whose masses and widths are measured to be where the first uncertainties are statistical and the second
systematic. The results are consistent with a previous LHCb measurement using a
prompt sample. Evidence of a new
state is found with a local significance of , whose mass and width
are measured to be and , respectively. In addition, evidence of a new decay mode
is found with a significance of
. The relative branching fraction of with respect to the
decay is measured to be , where the first
uncertainty is statistical, the second systematic and the third originates from
the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb
public pages
Measurement of the ratios of branching fractions and
The ratios of branching fractions
and are measured, assuming isospin symmetry, using a
sample of proton-proton collision data corresponding to 3.0 fb of
integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The
tau lepton is identified in the decay mode
. The measured values are
and
, where the first uncertainty is
statistical and the second is systematic. The correlation between these
measurements is . Results are consistent with the current average
of these quantities and are at a combined 1.9 standard deviations from the
predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb
public pages
Multidifferential study of identified charged hadron distributions in -tagged jets in proton-proton collisions at 13 TeV
Jet fragmentation functions are measured for the first time in proton-proton
collisions for charged pions, kaons, and protons within jets recoiling against
a boson. The charged-hadron distributions are studied longitudinally and
transversely to the jet direction for jets with transverse momentum 20 GeV and in the pseudorapidity range . The
data sample was collected with the LHCb experiment at a center-of-mass energy
of 13 TeV, corresponding to an integrated luminosity of 1.64 fb. Triple
differential distributions as a function of the hadron longitudinal momentum
fraction, hadron transverse momentum, and jet transverse momentum are also
measured for the first time. This helps constrain transverse-momentum-dependent
fragmentation functions. Differences in the shapes and magnitudes of the
measured distributions for the different hadron species provide insights into
the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb
public pages
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