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Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
Ahn J. H.
Aiken T.
Aime A.
Ajlan A.
Akalin M.
Akaydin E.
Akeel N.
Akgor U.
Akhtar M. A.
Akhter Rahman M. M.
Akilli H.
Akin E.
Akkour K.
Akmenkalne L.
Al Abdallah M.
Al Awwad S.
Al Habes H.
Al Maadany F. S.
Al Raddadi R.
Al-Habib A.
Al-Habsi R.
Al-Ishaq Z.
Al-Khayal K.
Al-Masri M.
Al-Mohammad A.
Al-Mukhtar A.
Al-Najjar H.
Al-Omishy H.
Al-Sarireh B.
AL-Sayed M.
Al-Tamimi Y.
Alaa S.
AlAamer O.
Aladeojebi A.
Alam F.
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Alamri A.
Alanbuki A.
Alatar A.
Alawneh F.
Alazawi D.
Albertsmeier M.
Albi Martin B.
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Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
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Abad-Motos A.
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Whelan P.
Whisker L.
Whitehall E.
Whitmore H.
Wilkin R.
Wilkins A.
Williams G.
Williams J.
Williams K.
Williams M. A.
Williams T.
Williamson K.
Wilson M.
Wimberger P.
Wimmer A.
Winnand P.
Winter D.
Winter S.
Wolfer S.
Wong M. P. K.
Wong S.
Wong W. J.
Woodham A.
Woodun H.
Worku D.
Wright G.
Wullschleger M.
Wustrack R.
Xenaki S.
Xu M. J.
Xyda S. E.
Xynos E.
Yahaya A. S.
Yanez C.
Yang W.
Yassin N.
Ye G.
Yesantharao P.
Yesilyurt D.
Yetkin G.
Yiallourou A.
Yildirim A.
Yildiz A.
Ying Y.
Yip V.
Yordanov S.
Young R.
Yousof E. A.
Youssef A.
Youssef M.
Yuksel E.
Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Enhancing the Specificity of Recombinase-Mediated Genome Engineering through Dimer Interface Redesign

Author: Andrew C. Mercer (1313703)
Carlos F. Barbas (19478)
Mark C. Wallen (800888)
Ryan D. Tingle (1313706)
Shannon J. Sirk (510690)
Thomas Gaj (510689)
Publication venue
Publication date
Field of study

Despite recent advances in genome engineering made possible by the emergence of site-specific endonucleases, there remains a need for tools capable of specifically delivering genetic payloads into the human genome. Hybrid recombinases based on activated catalytic domains derived from the resolvase/invertase family of serine recombinases fused to Cys<sub>2</sub>-His<sub>2</sub> zinc-finger or TAL effector DNA-binding domains are a class of reagents capable of achieving this. The utility of these enzymes, however, has been constrained by their low overall targeting specificity, largely due to the formation of side-product homodimers capable of inducing off-target modifications. Here, we combine rational design and directed evolution to re-engineer the serine recombinase dimerization interface and generate a recombinase architecture that reduces formation of these undesirable homodimers by >500-fold. We show that these enhanced recombinases demonstrate substantially improved targeting specificity in mammalian cells and achieve rates of site-specific integration similar to those previously reported for site-specific nucleases. Additionally, we show that enhanced recombinases exhibit low toxicity and promote the delivery of the human coagulation factor IX and α-galactosidase genes into endogenous genomic loci with high specificity. These results provide a general means for improving hybrid recombinase specificity by protein engineering and illustrate the potential of these enzymes for basic research and therapeutic applications

The Francis Crick Institute

B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models

Author: Alberto R. Rodriguez
Alessia Liguori
Allan deCamp
Bettina Groschel
Bonsignori
Colin Havenar-Daughton
Cyster
David Nemazee
Deli Huang
Duan
Greg Martin
James E. Voss
Jenny Tuyet Tran
Kong
Mark Pintea
Nicole Phelps
Oleksandr Kalyuzhniy
Parks
Patrick D. Skog
Piot
Rita Al-Kolla
Robert K. Abbott
Ryan Tingle
Sabrina A. Volpi
Sangesland
Sergey Kupryianov
Sergey Menis
Shane Crotty
Sophia M. Villegas
Tanya R. Blane
Theresa C. Thinnes
Torben Schiffner
Umotoy
William R. Schief
Publication venue: 'Proceedings of the National Academy of Sciences'
Publication date
Field of study

Crossref

On the generation of deep focus earthquakes in subduction zones

Author: A P W Hodder
B E Hobbs
C B Raleigh
C Frohlich
C M Sung
C Meade
C Meade
D T Griggs
D T Griggs
D T Griggs
D T Griggs
E Orowan
F Birch
F F Evison
F F Evison
H Benioff
H W Green
H W Green
H W Green
H W Green
H W Green
H W Green
H W Green
J G Ryan
J Morris
J R Vaisnys
J W Minear
J Y Ning
Jie-Yuan Ning
L Liu
M Ogawa
M Sakuyama
N Tingle
P C Burnley
P C Burnley
P C Burnley
P Nehlig
P W Bridgman
R J Alexander
R Jeanloz
R Jeanloz
R L Post
R S Coe
S H Kirby
S X Zang
S X Zang
Shao-Xian Zang
T Iidaka
Y Furukawa
Y Tatsumi
Publication venue: 'Springer Science and Business Media LLC'
Publication date
Field of study

Crossref

Vaccination induces broadly neutralizing antibody precursors to HIV gp41

Author: Adachi Yumiko
Allen Joel D.
Alt Frederick W.
Amara Rama R.
Baboo Sabyasachi
Batista Facundo D.
Briney Bryan
Burton Dennis R.
Carnathan Diane G.
Cheng Hwei-Ling
Cho So Yeon
Cottrell Christopher A.
Crispin Max
Crotty Shane
Davis Jillian
Diedrich Jolene K.
Elsliger Marc A.
Eskandarzadeh Saman
Flynn Claudia T.
Georgeson Erik
Grigoryan Gevorg
Havenar-Daughton Colin
Himansu Sunny
Hu Xiaozhen
Huang Jiachen
Hurtado Jonathan
Irimia Adriana
Kalyuzhniy Oleksandr
Kirsch Kathrin H.
Kubitz Michael
Kulp Daniel W.
Landais Elise
Lee Chang-Chun D.
Lee Jeong Hyun
Lewis Vanessa
Liang Chi-Hui
Liguori Alessia
Lin Ying-Cing
Marina-Zárate Ester
McKenney Katherine
Nair Usha
Ngo Julia T.
Ozorowski Gabriel
Paulson James C.
Pecetta Simone
Phelps Nicole
Phung Ivy
Rantalainen Kimmo
Ray Rashmi
Rodriguez Oscar L.
Ruiz Jennifer
Saha Swati
Schief William R.
Schiffner Torben
Schulze Steven
Serra Andreia M.
Sesterhenn Fabian
Shields Kaitlyn
Silvestri Guido
Skog Patrick D.
Smith Melissa L.
Sok Devin
Spencer Skye
Swanson Olivia
Tian Ming
Tingle Ryan D.
Toy Laura
Wang Xuesong
Ward Andrew B.
Watson Corey T.
Willis Jordan R.
Wilson Ian A.
Yates John R.
Zhou Jianfu
Zhou Xiaoya
Publication venue
Publication date: 01/06/2024
Field of study

A key barrier to the development of vaccines that induce broadly neutralizing antibodies (bnAbs) against human immunodeficiency virus (HIV) and other viruses of high antigenic diversity is the design of priming immunogens that induce rare bnAb-precursor B cells. The high neutralization breadth of the HIV bnAb 10E8 makes elicitation of 10E8-class bnAbs desirable; however, the recessed epitope within gp41 makes envelope trimers poor priming immunogens and requires that 10E8-class bnAbs possess a long heavy chain complementarity determining region 3 (HCDR3) with a specific binding motif. We developed germline-targeting epitope scaffolds with affinity for 10E8-class precursors and engineered nanoparticles for multivalent display. Scaffolds exhibited epitope structural mimicry and bound bnAb-precursor human naive B cells in ex vivo screens, protein nanoparticles induced bnAb-precursor responses in stringent mouse models and rhesus macaques, and mRNA-encoded nanoparticles triggered similar responses in mice. Thus, germline-targeting epitope scaffold nanoparticles can elicit rare bnAb-precursor B cells with predefined binding specificities and HCDR3 features.</p

Southampton (e-Prints Soton)

Enhancing the Specificity of Recombinase-Mediated Genome Engineering through Dimer Interface Redesign

Author: Akopian A.
Andrew C. Mercer
Arnould S.
Ashworth J.
Atwell S.
Bai H.
Bibikova M.
Bolusani S.
Bonnet J.
Buchholz F.
Buchholz F.
Carlos F. Barbas
Cheng A. A.
Coluccio A.
Cong L.
Cornu T. I.
Cradick T. J.
Doyon Y.
Dreier B.
Dreier B.
Ellis B. L.
Eroshenko N.
Fajardo-Sanchez E.
Friedland A. E.
Fu Y.
Gabriel R.
Gaj T.
Gaj T.
Gaj T.
Gaj T.
Gersbach C. A.
Gersbach C. A.
Gonzalez B.
Gordley R. M.
Gordley R. M.
Grindley N. D.
Guo J.
Haykinson M. J.
Isalan M.
Jinek M.
Keenholtz R. A.
Keravala A.
Li X.
Liesner R.
Lim H. M.
Lombardo A.
Mali P.
Mark C. Wallen
Mercer A. C.
Miller J. C.
Miller J. C.
Moehle E. A.
Nohaile M. J.
Olivares E. C.
Osborn M. J.
Pattanayak V.
Proudfoot C.
Reyon D.
Ritacco C. J.
Ryan D. Tingle
Sander J. D.
Sanderson M. R.
Sarkar I.
Sclimenti C. R.
Segal D. J.
Segal D. J.
Shannon J. Sirk
Siuti P.
Smith M. C.
Szczepek M.
Thomas Gaj
Thyagarajan B.
Urnov F. D.
Voziyanov Y.
Yang W.
Publication venue: 'American Chemical Society (ACS)'
Publication date
Field of study

Crossref

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

Crossref

Delaying surgery for patients with a previous SARS-CoV-2 infection

Author: A A Ali Karar
A A Kerawala
A A Marra
A Abad Gurumeta
A Abad-Motos
A Abdelmajeed
A Abdelrahman
A Abdelsamed
A Abdulkareem
A Aboelkassem Ibrahim
A Abouassi
A Abreu da Silva
A Abubakar
A Acher
A Aderombi
A Adeyeye
A Adiamah
A Aggarwal
A Aghayeva
A Agnes
A Agrawal
A Ahmeidat
A Aimé
A Ajlan
A Al-Habib
A Al-Mohammad
A Al-Mukhtar
A Aladeojebi
A Alamri
A Alanbuki
A Alatar
A Alburakan
A Alfaro-Goldaracena
A Alhamed
A Alhefdhi
A Almeciga
A Almeida
A Alomair
A Alonso Poza
A Alsaif
A Anastasi
A Antic
A Anzak
A Aprile
A Arminio
A Arulanantham
A Askari
A Asqalan
A Athanasiou
A Ayhan
A Ayman
A Ayubi
A Azizi
A B Martins
A Bacon
A Baker
A Balakrishnan
A Bandiera
A Banerjee
A Barrabe
A Beamish
A Bellacci
A Belli
A Belvedere
A Benkabbou
A Bhalla
A Bhangu
A Billè
A Bin Nasser
A Biondi
A Blatt
A Blazquez Martin
A Boddy
A Bokhari
A Bondurri
A Boulton
A Boutall
A Branquinho
A Brunelli
A Brunt
A Bruscino
A Budacan
A Burahee
A Böttcher
A C Almeida
A C Deus
A C Roslani
A C Soares
A C Vieira Paiva Lopes
A Caiado
A Camillo
A Canas-Martinez
A Cano
A Carabias
A Chandock
A Charalabopoulos
A Che Jusoh
A Chebaro
A Chessa
A Chiappini
A Chitul
A Choudhry
A Chowdhury
A Colquhoun
A Conesa
A Cordova
A Costanzi
A Cotoia
A Cotter
A Crichton
A Cuadrado-García
A Currie
A Cvetkovic
A D Bueno Cañones
A D Rajgor
A D Zakaria
A D'Amore
A D'Urso
A Daly
A Davies
A Day
A De Gea Rico
A De Manzoni Garberini
A De Pablo García-Cuenca
A De Troia
A De Virgilio
A Dehal
A Desai
A Di Bartolomeo
A Di Bella
A Di Somma
A Diamantis
A Doyle
A Durrani
A E Arikan
A E Sherif
A Eastmond
A El Ouahabi
A Elawad
A Eldaly
A Elhamshary
A Esposito
A Esteban
A Ezanno
A Fadzli
A Fagotti
A Fancellu
A Farsi
A Faustino
A Fazenda
A Fernández-López
A Ferrero
A Ferrés
A Fiorini
A Fisher
A Fletcher
A Fowler
A Fox
A Frampton
A Frankel
A Frati
A Freitas
A Frena
A Fuson
A G Carta
A G Zarabini
A Gabre-Kidan
A Gagliano
A Gainza
A Gatti
A Gattolin
A Gaunt
A Geddes
A Gegúndez Simón
A Ghanbari
A Ghannam
A Giaglaras
A Gianni
A Giblin
A Gillis
A Gklavas
A Glencer
A Gomes da Costa
A Gori
A Goyal
A Gronchi
A Gueutier
A Guglielmi
A Guimarães
A Gupta
A Gutierrez Calvo
A Gvaramadze
A Gómez-Pedraza
A H Hussain
A H Khan
A Habeeb
A Hainsworth
A Hamad
A Hannah
A Hanson
A Harky
A Hasenburg
A Hawkins
A Haynes
A Haynes
A Henry
A Herman
A Hernández Gutierrez
A Heuer
A Hmedat
A Hogan
A Hunt
A I Gutiérrez Fernández
A I Kilani
A I Soriano
A I Tercero-Uribe
A Ibrahim
A Ionescu
A Jah
A Jain
A Jamal
A Jibril
A Jiménez
A Joshi
A Jotic
A K Ali
A K Andrade
A K Lala
A K Scafa
A K Zengin
A Kahn
A Kamocka
A Kanatas
A Kappenberger
A Karamarkovic
A Karim
A Kattakayam
A Kaufmann
A Kawai
A Kent
A Khajuria
A Khan
A Khoja
A Kirk
A Kisiel
A Kler
A Kocataş
A Koh
A Kolias
A Kollàr
A Kolusarı
A Kourdouli
A Kouyoumdjian
A Kredan
A Kumar
A Königsrainer
A L De Oliveira López
A L Ebbehøj
A L Picardo
A Laforest
A Lagares
A Laios
A Laird
A Landaluce-Olavarria
A Lanzon
A Larentzakis
A Lauretta
A Lim
A Loayza
A Loehrer
A Lopez Abad
A Louvrier
A Lovece
A Lowery
A Lyons
A Lázaro
A López Campillo
A M Abbas
A M Baietti
A M Castaño-Leon
A M Correia
A M Lacy
A M Majbar
A M Minaya Bravo
A M Ntziovara
A M Pathanki
A M Perrone
A M Scanu
A Macchi
A Madhavan
A Madkhali
A Maffioli
A Maffuz-Aziz
A Maghrabi
A Maiga
A Majkowska
A Mansuri
A Mantevas
A Marano
A Marchbank
A Marco Garrido
A Margalit
A Martin-Ucar
A Martinez German
A Marçal
A Mashat
A Maw
A McCanny
A Mccarthy
A McLennan
A McMillan
A Melo
A Menon
A Merchan
A Merdrignac
A Miljković
A Millan
A Mingoli
A Minicozzi
A Mirabella
A Modabber
A Mohammad
A Moro
A Morris
A Morsi
A Morton
A Mosca
A Moumen
A Muratore
A Mustafa
A N Sanli
A Nabil
A Nakas
A Nawawi
A Nobre Pinto
A Nogués
A Oar
A Oliveira
A Osorio
A Otero
A Ovaitt
A P Ferreira Pinto
A P Pezzuto
A Parello
A Parente
A Parseliunas
A Patel
A Patel
A Paunovic
A Pearce
A Pereira
A Pereira-Neves
A Peryt
A Petrillo
A Piras
A Pisani Ceretti
A Pisanu
A Polydorou
A Popoola
A Porcu
A Provozina
A Pucar
A Pérez Núñez
A Qasem
A Quennell
A Qureshi
A Ramachandran
A Ramos Bonilla
A Ramwell
A Ribeiro
A Rizzi
A Robinson
A Robson
A Rodolakis
A Rodrigues
A Rodriguez Fraga
A Rogers
A Rogers
A Romero de Diego
A Rowcroft
A Ruivo
A Ruiz Escobar
A Ruzzenente
A S Bodla
A S Coonar
A S Crugnale
A S Memon
A S Mohamed Sidek
A S Yahaya
A Sabry
A Sachdeva
A Sagnotta
A Said Bayazeed
A Salamah
A Salazar
A Saleem
A Samih
A Samir Abdelaal
A Samkari
A Samy
A Santoro
A Sanz Larrainzar
A Saratziotis
A Sarin
A Sayasneh
A Scalabre
A Schache
A Seguin-Givelet
A Seleim
A Sgrò
A Shabana
A Sharkey
A Sharma
A Sheel
A Shenfine
A Sherif
A Shuwayyah
A Singh
A Soares
A Solth
A Souadka
A Spinelli
A Ssentongo
A Stanimirovic
A Stavroglou
A Stefanovic
A Stepanyan
A Subocius
A Sultana
A Sutherland
A Syllaios
A Sánchez-Pernaute
A Taddei
A Taibi
A Tailor
A Tang
A Tedde
A Thomas
A Thompson
A Tojal
A Tooulias
A Torne
A Torres
A Townson
A Trivic
A Tufo
A Turnbull
A Urbani
A Urbieta
A Usai
A Valente da Costa
A Vallance
A Valle Rubio
A Varazzani
A Vazquez Fernandez
A Vezakis
A Vieira
A Vignali
A Vitali
A Wali
A Wilkins
A Wimmer
A Woodham
A Y Azzam
A Yiallourou
A Yıldırım
A Yildiz
A Youssef
A Zubaidi
A Zullo
A Älgå
Abd Elazeem Has
Abhinav Tiwari
Abigail Vallance
Adesoji Ademuyiwa
Adesoji O Ademuyiwa
Adrian Marchbank
Ahmad Qureshi
Akshay Patel
Alan McNeill
Alessandro Brunelli
Alessandro Gronchi
Alex Alamri
Alex Wilkins
Alexandra Colquhoun
Alexis P Arnaud
Aman S Coonar
Amanpreet Brar
Ana Minaya-Bravo
Ana Minaya-Bravo
Ana Minaya-Bravo
Ana Minaya-Bravo
Anant Desai
Anant Desai
Andreas A Schnitzbauer
Andreas K Demetriades
Andrew G Schache
Andrew Knight
Andrew Loehrer
Andrew Schache
Andrey Litvin
Aneel A Bhangu
Aneel A Bhangu
Aneel Bhangu
Angelos Kolias
Angelos Kolias
Anna Fagotti
Antonino Spinelli
Antonio Ramos-De la Medina
April C Roslani
Arda Isik
Arnav Agarwal
B A Fahey
B Al-Sarireh
B Albi Martin
B Alhassan
B Ayub
B B Ozmen
B Baca
B Bakmaz
B Banky
B Barmayehvar
B Barrat
B Bartalucci
B Bozkırlı
B Brown
B Caimari
B Challacombe
B Chumbinho
B Cimenoglu
B Cirillo
B Citgez
B Collard
B Costeira
B Cros
B Davidson
B De Andrés Asenjo
B De Simone
B Devauchelle
B Dias
B Diéguez
B Díaz-Feijoo
B El Ahmadi
B Gil Ibañez
B Giray
B Gricks
B Griffiths
B Grotenhuis
B Gális
B Göksoy
B J Mehigan
B Jayasankar
B Johnston
B Kajmaković
B Keeler
B Kidane
B Knowles
B Kocer
B Kotlar
B Kovacevic
B Lamb
B Le Roy
B Lieske
B Malgras
B Manku
B Mantoglu
B Martin-Perez
B McAree
B Narice
B Nunez-Garcia
B Patrício
B Pramodana
B Pérez-Saborido
B Rai
B S Kamera
B S Ong
B Seeliger
B Sheu
B Soyak
B Steel
B Swinson
B Tadic
B Thakur
B Ugarte-Sierra
B Vieira
B Vieira
B Wadham
Bandara Gbk
Benjamin Lamb
Brett E Dawson
Brittany K Bankhead-Kendall
C A Espinosa
C A Guariglia
C Abatini
C Agostini
C Allemand
C Alurralde
C Anthoulakis
C Arican
C Ashmore
C Aydin
C Azevedo
C B Kulle
C Baker
C Baldi
C Barry
C Barry
C Bassi
C Baía
C Belluco
C Bergamini
C Bescós
C Beyrne
C Bezede
C Bisset
C Boeker
C Bong
C Boyle
C Burgess
C Busch
C C Foo
C Cagigas Fernandez
C Camacho
C Canhoto
C Castro Ruiz
C Chan
C Chan
C Chan
C Checcucci
C Christou
C Collins
C Corbellini
C Corvera
C Cotsoglou
C Cullinane
C Cunha
C Dawson
C Delimpalta
C Denet
C Di Martino
C Donohue
C Eiriz Fernandez
C Evans
C Evans
C Eveno
C F Feo
C Ferreira
C Ferron
C Fitzgerald
C Fleming
C Fotopoulou
C Frattaruolo
C Freyschlag
C G Gil
C G Mitrofan
C Gambacciani
C Gan
C Gaskill
C Gemmell
C Gill
C Giménez Francés
C Gracia-Roche
C Grieco
C Grundy
C Guerci
C Halloran
C Hammer
C Hardie
C Heaton
C Heron
C Hidalgo Salinas
C Hill
C Houlden
C J Gómez Díaz
C Jelley
C Jezieniecki
C Kalfountzos
C Kamphues
C Kang
C Kelty
C Kloppers
C Knowles
C Konstantinou
C Kontovounisios
C Korais
C Kurze
C Kuzmanovic
C L Roland
C Langdon
C Leal
C Leonardo
C Lewis-Lloyd
C Lima da Silva
C Linari
C Loh
C Long
C Lopes
C Louis-Sylvestre
C M Chiesa-Estomba
C Magee
C Marchitelli
C Martí
C Martínez Chicote
C Martínez-Pinedo
C McDonald
C McNaught
C Mellor
C Michalski
C Millward
C Moliner-Sánchez
C Mulligan
C Murphy
C Nahm
C Nardi
C Nessim
C Newton
C Nitschke
C Norcini
C O'Donnell
C Olona
C P Lombardi
C Parmar
C Pedrazzani
C Peirce
C Peluso
C Pereira
C Piazza
C Poch
C Pompili
C Praetorius
C Price
C Ratto
C Redondo
C Rey Valcarcel
C Riediger
C Riley
C Rossborough
C Roy
C Russell
C S Betz
C S Faria
C Saleh
C Sanchez Rodriguez
C Santanach
C Sarre
C Sarre
C Schilling
C Schineis
C Secosan
C Skoulakis
C Smith
C Smith
C Sohrabi
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J A Tan
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J Abu
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Jalid Sehouli
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James C Glasbey
James C Glasbey
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U M Jariod Ferrer
U Ribeiro Junior
U Ronellenfitsch
U Selbong
U Speth
V Alexoudi
V Annessi
V Bascarevic
V Capizzi
V Chiarella
V Cozza
V D Mandato
V De Simone
V Devezas
V Drubay
V Duque-Mallén
V Fernandes
V Garcia Soria
V García Pineda
V Gata
V Granata
V H Baptista
V Hudson
V I Ribeiro
V Irvine
V J García Porcel
V Javurkova
V Jimenez
V Jokic
V Kakotkin
V Kantola
V Kasivisvanathan
V Konstantinovic
V Kubyshkin
V Lago
V Linz
V Lizzi
V Luoma
V Mahendran
V Markovic
V Mastrofilippo
V Mazzaferro
V Milutinović
V Miu
V Muñoz-Atienza
V Ng
V Ng
V Oktseloglou
V Ozben
V Papadopoulos
V Picotti
V Pinto
V Pla-Marti
V Pérez Simón
V Quintodei
V Rizzo
V Rossi
V S Ban
V S Kolli
V S Rodrigo
V Testa
V Tonini
V Tsaousis
V Turrado-Rodriguez
V Valbuena Jabares
V Valtzoglou
V Velchuru
V Vigorita
V Vujanac
V Yip
V Zamvar
V Šćepanović
Veeru Kasivisvanathan
W Butt
W Campbell
W Cymes
W Garrett
W H Khan
W J Wong
W Knight
W Lee
W Marx
W McCormick
W McGahan
W Mugla
W Oosterlinck
W Raby-Smith
W Smolka
W Van Houdt
W Yang
Willemijn van der Plas
Wong Mpk
X De Sousa
X Morales
X S Tan
Y Aawsaj
Y Al-Tamimi
Y Arkha
Y Ayasra
Y Bashir
Y El Bouazizi
Y Fayed
Y H Lam
Y Kanemitsu
Y Kara
Y Kirmizi
Y Levy-Zauberman
Y Litvina
Y Perez
Y T Liew
Y Tanase
Y Viswanath
Y Ying
Z Al-Ishaq
Z Aldayri
Z Aliyeva
Z Bayhan
Z Chia
Z Dzamic
Z H Belkhadir
Z Inic
Z Jawad
Z Jezdic
Z Katusic
Z Krivokapic
Z Lakkis
Z Li
Z M Barrett-Brown
Z Mahasin
Z Seymour
Z Vilendecic
Z Zakaria
Á De la Hoz Rodríguez
Á Fernández Camuñas
É Ryan
Ž Grubač
А Камалов
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

Not availabl

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Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.

Author: Aawsaj Y
Abad Gurumeta A
Abad-Motos A
Abate E
Abatini C
Abbadessa F
Abbas AM
Abbassi-Ghadi N
Abbott D
Abbott T
Abbott TEF
Abd Elazeem HAS
Abdalla M
Abdallah M
Abdelaal SA
Abdeldayem H
Abdelkarem MM
Abdelkarim M
Abdelmajeed A
Abdelrahman A
Abdelrahman S
Abdelsamed A
Abdou M
Abdulkareem A
Abdulwahed E
Abdur-Rahman L
Abel MK
Abellan M
Abosamak NE
Abou Chaar MK
Abou-Khalil J
Abouassi A
Aboulkassem H
Abreu da Silva A
Abu Za'nouneh FJ
Abu J
Abu-Nayla I
Abubakar A
Abukhalaf S
Acebes Garcia F
Achalandabaso Boira M
Acher A
Acrich E
Adamina M
Adamina M
Adamoli L
Addae-Boateng E
Ademuyiwa AO
Aderombi A
Adeyeye A
Adiamah A
Adishesh M
Agapov M
Agarwal A
Aggarwal A
Aghayeva A
Agilinko J
Agnes A
Agostini C
Agoston P
Agrawal A
Agresta F
Aguado H
Aguzzoli L
Ahad S
Ahmadi N
Ahmed NR
Ahmeidat A
Ahn JH
Aiken T
Aime A
Ajlan A
Akalin M
Akaydin E
Akeel N
Akgor U
Akhtar MA
Akilli H
Akin E
Akkour K
Akkulak M
Akmenkalne L
Al Abdallah M
Al Abdel S
Al Awwad S
Al Habes H
Al Maadany FS
Al Raddadi R
AL Sayed M
Al-Habib A
Al-Habsi R
Al-Ishaq Z
Al-Khayal K
Al-Masri M
Al-Mohammad A
Al-mukhtar A
Al-Najjar H
Al-omishy H
Al-Sarireh B
Al-Tamimi Y
Alaa S
AlAamer O
Aladeojebi A
Alakaloko F
Alam F
Alam N
Alam R
Alameer E
Alamri A
Alamri A
Alanbuki A
Alatar A
Alawneh F
Alazawi D
Albertsmeier M
Albertsmeiers M
Albi Martin B
Alburakan A
Alcaide Matas F
Alconchel F
Aldayri Z
Aldecoa Ansorregui I
Alderson D
Aldokali N
Aleksic L
Alemanno G
Alexoudi V
Alfaro-Goldaracena A
Alfieri S
Alga A
Alghamdi M
Alhalal H
Alhamed A
Alharthi M
Alharthi R
Alhassan B
Alhassan N
Alhefdhi A
Ali AK
Ali M
Ali MF
Ali S
Aliyeva Z
Aljanadi F
Aljiffry M
Alkadeeki GZ
Alkarak S
Allemand C
Allison J
Almalik O
Almasri M
Almeciga A
Almeida A
Almeida AC
Almeida JI
Almgla N
Almond M
Almond M
Alnumani T
Alobeed O
Alomair A
Alonso de la Fuente N
Alonso Poza A
Alonso-Lamberti L
Alotaibi N
Alqannas M
Alresaini F
Alriyees L
Alsaif A
Alsaif F
Alsalamah R
Alsaraireh O
Alselaim N
Alser O
Alshaar M
Alshahrani M
Alshammari S
Alshareea E
Alsharif F
Alshaygy I
Alshryda S
Alsobhi S
Althobaiti W
Altintoprak F
Alurralde C
Alvarez E
Alvarez MR
Alyami M
Alzamanan M
Amaral MJ
Ameerally P
Amira G
Amonkar S
Amorim E
Ampollini L
Amrani L
Anania G
Anastasi A
Anchuelo Latorre J
Andaleeb U
Andaya V
Andrade AK
Andrade R
Andrijasevic S
Aneke IA
Ang K
Angele M
Angelo M
Angelou D
Angelou K
Annamalai S
Annessi V
Ansarin M
Anthoulakis C
Antic A
Antic S
Antonakis P
Antoniades K
Antonopoulou MI
Anula R
Anwar S
Anzak A
Aoun S
Aprile A
Aquila F
Aragon Achig EJ
Aremu I
Aremu M
Aresu G
Aribi N
Aribi S
Arican C
Arif T
Arigoni M
Arikan AE
Arkadopoulos N
Arkha Y
Armao T
Armatura G
Arminio A
Arnaud AP
Arrangoiz R
Arrowsmith L
Artigues E
Arulanantham A
Asaad P
Ascensao J
Ashcroft J
Ashmore C
Ashoush F
ASiT AS
Askari A
Asqalan A
Assaf M
Assalaarachchi H
Asti E
Astreidis I
Athanasakis E
Athanasiou A
Athayde Nemesio R
Atherton R
Athwal R
Atici DS
Atta R
Attia D
Augestad KM
Australasian T
Avci EK
Avlund T
Awad S
Ayasra F
Ayasra F
Ayasra Y
Aydin C
Ayhan A
Ayman A
Ayorinde J
Aytac E
Ayub B
Ayubi A
Azam M
Azamat IF
Azevedo C
Azevedo J
Azevedo J
Azevedo P
Azizeldine MG
Azizi A
Azzam AY
Baaij J
Babar MS
Baca B
Bachler T
Bacic G
Bacon A
Badalamenti G
Badellino E
Badra R
Baena Sanfeliu E
Baeza Pintado N
Bagraith K
Baia C
Baia M
Baiao JM
Baietti AM
Baig M
Bailon M
Bajomo O
Baker A
Baker C
Baker O
Bakmaz B
Bakolas G
Balabel M
Balakrishnan A
Balasubramaniam D
Balasubramanian I
Baldari L
Baldi C
Baldini E
Balercia P
Balik E
Ballabio M
Ballal M
Ballouhey Q
Baloyiannis I
Bambina F
Ban VS
Bandara GBK
Bandiera A
Bandovas JP
Banerjee A
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Bankhead-Kendall BK
Banky B
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Baptista VH
Barabasz M
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Bardet J
Barisic G
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Barlow E
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Barod R
Baron R
Barra F
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Barrat B
Barrett J
Barrett-Brown ZM
Barrios O
Barry C
Barry C
Barry M
Bartalucci B
Bartolini I
Bartolucci P
Bascarevic V
Basendowah M
Bashir Y
Bass G
Bassi C
Bates H
Bath M
Batistotti P
Batjer HH
Batstone M
Batstone M
Battista MJ
Bauer M
Baumber R
Baxevanidou K
Baxter K
Bayazeed SA
Bayhan Z
Beamish A
Beard D
Beasley N
Beatson K
Becerra Garcia FC
Bechri H
Becker R
Beech N
Bekele D
Bekheit M
Belcher E
Belia F
Belkhadir ZH
Bellacci A
Bellanti L
Belli A
Bello J
Bellora P
Belluco C
Beltramini GA
Beltran de Heredia J
Belvedere A
Benavides Buleje JA
Benkabbou A
Bennetts J
Benson O
Benson RA
Benson RA
Bergamini C
Bergeat D
Bergonzani M
Bernal-Sprekelsen JC
Bernante P
Bernardi D
Bernasconi M
Bernon M
Berry R
Berselli M
Bertelli G
Bertoglio P
Bertolani E
Bertoli G
Bescos C
Beswick D
Bettoni J
Betz CS
Bewarder J
Beyer K
Beyrne C
Bezede C
Bhalla A
Bhangu A
Bhangu A
Bhangu AA
Bhangu AA
Bhasin S
Bhatti MI
Biala M
Bianchi MF
Bianchini M
Bianco F
Bianco F
Biasini M
Biasoni D
Bichoo R
Biel JR
Bigay K
Bilgin IA
Bille A
Bin Nasser A
Bin Traiki T
Biondi A
Bisagni P
Bisset C
Bissolotti G
Blackwell L
Blake D
Blanco-Colino R
Blanco-Colino R
Blas Laina JL
Blatt A
Blazer D
Blazquez Martin A
Boal M
Bobinski M
Boccalatte L
Bocchialini G
Bocciolone L
Boddaert G
Boddy A
Bodla AS
Boeck MA
Boeker C
Boettcher A
Bogani G
Bogdanovic I
Bokhari A
Boland M
Bolster-van Eenennaam M
Bolt J
Bonavina G
Bonavina L
Bonci E
Bond-Smith G
Bondurri A
Bong C
Boni L
Bonnet S
Bordenave M
Borges F
Borges N
Borghi F
Borgonovo G
Bork U
Borroni G
Bortolasi L
Bouchagier K
Bouche P
Boucher S
Bouliaris K
Boulton A
Bourke G
Boussedra S
Boutall A
Boutros M
Boutros M
Boutros M
Bowden J
Bowman S
Boyce R
Boyd E
Boyd-Carson H
Boyle C
Boyle T
Bozanovic T
Bozkirli B
Bozkurt E
Bozkurt MA
Brachini G
Bradshaw L
Bradulskis S
Bramis K
Brana I
Branquinho A
Brar A
Bratt D
Bravo Infante R
Breda D
Breen KA
Breheret R
Breik O
Bretherton C
Brewer H
Brian E
Bright T
Bristow R
Brito da Silva F
Brixton G
Brock L
Brocklehurst M
Bromage S
Brooke-Smith M
Brown B
Brown K
Brown L
Brown O
Brown S
Brown S
Brunelli A
Brunelli A
Brunocilla E
Brunt A
Bruscino A
Bruzzaniti P
Buarque IL
Budacan A
Buddingh K
Bueno Canones AD
Buerba GA
Bugra D
Bulathsinhala S
Bumbasirevic U
Burahee A
Burg S
Burgan D
Burgess C
Burke J
Burke J
Burnside N
Busch C
Bussu F
Buta M
Butt U
Butt W
Byrne J
Byrne M
Bywater E
Cabezudo Noguera SF
Cadenelli P
Cadwell-Sneath S
Cagigal Ortega EP
Cagigas Fernandez C
Cahill J
Caiado A
Caimari B
Caina Ruiz R
Caird S
Cairncross L
Caja Vivancos P
Cakmak G
Calabro M
Callanan D
Calvo Espino P
Camacho C
Camillo' A
Caminsky N
Campagnaro T
Campain N
Campbell W
Campisi G
Canas-Martinez A
Candiani M
Candotti G
Canhoto C
Cano A
Cano-Valderrama O
Canonico G
Canotilho R
Cantalejo Diaz M
Cao H
Capelli P
Capezzuoli L
Capitan-Morales L
Capizzi V
Capoglu R
Capolupo GT
Carabias A
Caram EL
Carannante F
Carcoforo P
Cardoso N
Cardoso P
Caricato M
Carrano FM
Carrasco Prats M
Carroll P
Carta AG
Carter J
Caruana EJ
Caruana EJ
Caruana EJ
Caruso J
Carvello MM
Casati M
Casetti L
Casiraghi T
Cassinotti E
Castano-Leon AM
Castillejos-Molina RA
Catala Bauset JC
Catarzi L
Cato LD
Cavaleiro S
Cavalle Busquets P
Cayetano Paniagua L
Cazador Labat M
Cecchini L
Cecconello I
Cecire J
Celebi F
Celik H
Cellerino P
Cenciarelli S
Ceranic M
Ceretti PA
Cervellera M
Cervera I
Ceyhan GO
Chaar M
Chai AKW
Chakib O
Chakrabortee S
Challacombe B
Chan C
Chan C
Chan C
Chan CW
Chan E
Chan E
Chand M
Chandock A
Charalabopoulos A
Chardalias L
Charlton G
Chase T
Chatzikomnitsa P
Chaudhry D
Chaudhury M
Chavarrias N
Chebaro A
Checcucci C
Chen L
Chen L
Chen S
Chern H
Chessa A
Cheung LK
Chevallay M
Chew D
Chia Z
Chiappini A
Chiarella V
Chiarugi M
Chidambaram S
Chiesa-Estomba CM
Chiozza M
Chitul A
Chiva L
Choi D
Cholewa H
Chong L
Choolani Bhojwani E
Choong P
Chopra S
Choudhry A
Choudhury J
Chouillard E
Chowdhry MF
Chowdhury A
Choynowski M
Christensen P
Christensen P
Christidis P
Christoforidis D
Christou C
Chrysos E
Chu F
Chumbinho B
Chung E
Cianflocca D
Ciccarone F
Cicerchia PM
Cimenoglu B
Cintas Catena J
Cioffi SPB
Ciofic E
Cipriani R
Cirillo B
Cirocchi N
Cisternino G
Citgez B
Citterio D
Clark J
Claro M
Clatworthy S
Clifford R
Coccolini F
Cocozza E
Coe P
Coffey JC
Cohen P
Coiro S
Colak E
Colao Garcia L
Colino M
Collaborative C
Collard B
Colledan M
Collera P
Colletti G
Collins C
Collis J
Colloc T
Colombari RC
Colombo F
Colombo F
Colquhoun A
Colquhoun A
Combellack T
Comini LV
Conesa A
Confalonieri M
Conlon K
Connelly T
Connolly EM
Consorti G
Conti L
Conti L
Contis I
Cool P
Coonar AS
Coonar AS
Cope D
Corbellini C
Corbin S
Cordera F
Cordova A
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Correia de Sa T
Correia AM
Correia J
Correia S
Corrigan M
Corte Real J
Corvera C
Cosentino ML
Cosimelli M
Cossu ML
Costa Santos D
Costa M
Costa MJMA
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Costeira B
Costigan F
Cotoia A
Cotsoglou C
Cotte E
Cotter A
Cottu P
Coughlin P
Cox D
Coza I
Cozza V
Crank M
Creavin B
Cribb G
Crichton A
Cristian D
Cros B
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Cuadrado-Garcia A
Cukier M
Cullinane C
Cullivan O
Cuming T
Cunha C
Cunha MF
Cunha MF
Cunha R
Cunningham R
Curl-Roper T
Currie A
Cvetkovic A
Cymes W
D'Aloisio G
D'Amore A
D'Andrea G
D'Angelo G
D'Ugo D
D'Ugo S
D'Urso A
Dafnios N
Daiko H
Dainius E
Dakpe S
Daliya P
Daly A
Danias N
Daniels I
Davidson B
Davidson GH
Davies A
Davies E
Davies E
Davies RJ
Dawe N
Dawson BE
Dawson C
Day A
De Andres Asenjo B
De Andres Olabarria U
De Barros J
De Berardinis R
De Bree R
De Cicco R
De Crescenzo E
De Graaff M
De Iaco P
De la Hoz Rodriguez A
De la Rosa Abaroa MA
De Lacy FB
De Miguel Ardevines MDC
De Nardi P
De Oliveira Lopez AL
De Pablo Garcia-Cuenca A
De Palma G
De Pastena M
De Simone B
De Simone V
de Solorzano Aurusa OFJ
De Sousa X
De Toma G
De Troia A
De Vincenti R
De Virgilio A
Dehal A
Del Campo Martin M
Del Valle E
Delgado Fernandez J
Deligiannidis D
Delimpalta C
Dellaportas D
Delrio P
Demetriades AK
Demir H
Demirhan R
Demyttenaere S
Denet C
Dent H
Depalma N
Derkaoui Hassani F
Derksen T
Desai A
Desai A
Desai A
Desio M
Deus AC
Devauchelle B
Devezas V
Devine M
Di Bartolomeo A
Di Bella A
Di Candido F
Di Chiara F
Di Franco G
Di Giuseppe M
Di Martino C
Di Martino M
Di Marzo F
Di Saverio S
Di Saverio S
Di Somma A
Di Taranto G
Diamantis A
Dias B
Diaz Del Gobbo R
Diaz Pena P
Diaz Perez D
Diaz-Feijoo B
Dickson K
Dieguez B
Diez Alonso M
Diez-Valladares L
Dijan E
Dikicier E
DiLalla G
Dincer HA
Distler M
Divya GS
Dixon J
Djurisic I
Dokic M
Domingo S
Domingues JC
Dominguez I
Dominguez-Rosado I
Donati D
Donati DM
Dondi G
Donlon N
Donohue C
Dowdy S
Doyle A
Drake T
Drake TM
Drubay V
Duchalais E
Dudi-Venkata NN
Duff S
Dulgeroglu O
Dumitra S
Dumitra S
Dunderovic D
Dunne D
Dunne N
Dunning J
Duque M
Duque-Mallen V
Duran Ballesteros M
Duran-Valles F
Durrani A
Dwerryhouse S
Dwidar O
Dzamic Z
Dziakova J
Eardley N
Earley H
Eastmond A
Ebbehoj AL
Economopoulou P
Edmond M
Edmondson R
Edwards J
Edwards J
Edwards JG
Efthimiou M
Egan R
Egbeare D
Egbuchulem IK
Egoroff N
Eiriz Fernandez C
El Aamrani M
El Abbadi N
El Ahmadi B
El Bouazizi Y
El Ouahabi A
El-sayed I
Elawad A
Elayyan M
Elazzazy E
Elbe P
Eldaly A
Elena GDCR
ElFiky M
Elghazaly MS
Elhadi M
Elhamshary A
Elhoseiny M
Elhusseini M
Elkadi H
Elkaffas SMMM
Elkhayat H
Elliott JA
Elliott M
Ellojli I
Elmoslemany T
Elnemr M
Elqasabi MS
Elsey E
Elshaer M
Elsherbini I
Elson N
Elwatidy S
Emerson H
Emile S
Emiroglu M
Emmanuel K
Emslie K
Enjuto D
Ensenat Nora J
Ergun S
Erol T
Escartin J
Escobar P
Escola D
ESCP ESC
Esene I
Eskander M
Eskander P
Eskinazi D
Espin-Basany E
Espino Segura-Illa M
Espinosa CA
Espitalier F
Esposito A
Esposito G
Essam E
Essangri H
Estaire Gomez M
Esteban Agusti E
Esteban Sinovas O
Esteban A
Etchill E
Ethunandan M
EuroSurg
Evans C
Evans C
Evans J
Evans JP
Evans JP
Evans RPT
Evans S
Eveno C
Evoy D
Eweda M
Ezanno A
Fabbri N
Fabregas N
Fadzli A
Fagotti A
Fagotti A
Fahey BA
Fahim M
Fahmawee T
Falco G
Falcon GM
Fambrini M
Familiari P
Fancellu A
Faria CS
Farik S
Farma J
Farnesi F
Farooka WM
Farre Font R
Farrell R
Farsi A
Fasanmade K
Fathi NQ
Faulkner G
Faustino A
Fayed Y
Fazenda A
Fearon N
Federico P
Federico PNS
Fehervari M
Felli E
Fenton M
Feo CF
Feo CV
Fernandes U
Fernandes V
Fernandez Bernabe P
Fernandez Camunas A
Fernandez Pablos FJ
Fernandez Rodriguez P
Fernandez M
Fernandez PV
Fernandez-Lopez A
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Figueiredo de Barros I
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Publication venue: Br J Surg
Publication date: 11/11/2020
Field of study

BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; P = 0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas

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