10 research outputs found
Twofold Heck / 6Ï€-Electrocyclization and Regioselective Palladium(0)-Catalyzed Reactions of Brominated Thiophenes, Pyrroles, Imidazoles and Indoles
Get PDFThis thesis presents site-selective Suzuki-Miyaura reactions of 2,3,5-tribromo-thiophene, 2,4,5-tribromothiophene and 2,3,5-tribromo-N-methylpyrrole, which are controlled by steric and electronic parameters. Palladium-catalyzed Heck reactions of brominated thiophenes, N-methylimidazole, N-methylpyrrole and N-methylindole are also presented. The products were transformed by subsequent 6Ï€-electrocyclization and dehydrogenation to functionalized benzothiophenes, dibenzothiophenes, benzimidazoles, indoles and carbazoles, respectively
ChemInform Abstract: Synthesis of Functionalized Benzothiophenes and Dibenzothiophenes by Twofold Heck and Subsequent 6Ï€-Electrocyclization Reactions of 2,3-Dibromothiophenes and 2,3-Dibromobenzothiophenes.
No full textSynthesis of Dibenzothiophenes and Carbazoles by Sequential 'Tetra-Fold Heck/6[pi]-Electrocyclization/Dehydrogenation' Reactions of Tetrabromothiophene and Tetrabromo-N-methylpyrrole
No full textOne-Pot Halogen Dance/Negishi Coupling of Dibromothiophenes for Regiocontrolled Synthesis of Multiply Arylated Thiophenes
No full textSite-Selective Arylation of Alizarin and Purpurin Based on Suzuki-Miyaura Cross-Coupling Reactions
No full textSynthesis of Alkynylated Selenophenes by Site-Selective Sonogashira Reactions of Tetrabromoselenophene
No full textSite-Selective Synthesis of Arylated Indenones by Suzuki-Miyaura Cross-Coupling Reactions of 2,3,5-Tribromoinden-1-one
No full textNew protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis
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