4,928 research outputs found
Research training in a ‘real-life’ survey
A whole course or module is built round a survey research project devised in collaboration with a partner agency which may be an outside body (e.g. local government) or a unit in the teaching institution (such as a research group or the library). Other elements of the course/module, such as methodology, may extend and qualify understandings gained through the project
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Euglycemic Diabetic Ketoacidosis in Concurrent Very Low-carbohydrate Diet and Sodium-glucose Transporter-2 Inhibitor Use: A Case Report
Introduction: With the incredibly high incidence of Type 2 Diabetes in the current population of emergency department patients, it is critical for clinicians to understand the possible complications of the treatment of this disease. Medication like canagliflozin are more common to encounter on patient’s home medication lists and clinicians should be aware of how these medications, alone or combined with dietary modifications, can result in significant pathology and even mortality if not appropriately treated.Case Report: We report a case of a patient with type II diabetes mellitus who presented with euglycemic diabetic ketoacidosis in the setting of concurrent use of canagliflozin, a sodium-glucose transporter-2 (SGLT-2) inhibitor, and strict adherence to a low-carbohydrate ketogenic diet for weight control.Discussion: Euglycemic ketoacidosis has previously been observed in both diabetic and non-diabetic patients following strict ketogenic diets, as well as in diabetic patients being treated with SGLT-2 inhibitors.Conclusion: As more patients choose ketogenic diets for weight control and diabetes management, clinicians should be aware of this potentially life-threatening complication in patients concurrently taking SGLT-2 inhibitors
Flexural properties of the equine hoof wall
The equine hoof wall is a hard keratinous structure which transmits forces generated when the hoof contacts the ground to the skeleton of the horse. During locomotion, the hoof capsule is known to yield under impact resulting in an inward curvature of the dorsal wall and expansion of the heels. However, whilst researchers have studied the tensile and compressive properties of the hoof wall, there is a lack of data on the flexural properties in different locations around the hoof capsule.
In this study the flexural properties and hydration status of the hoof wall was investigated, in two orthogonal directions, in different locations around the hoof capsule. The hoof was divided into three regions: the dorsal-most aspect (toe); the medial and lateral regions (quarters) and the heels caudally. Beams were cut both perpendicular and parallel to the axis of the tubules, termed transverse and longitudinal beams respectively. Differences in the mechanical properties were then investigated using three-point bending tests.
There were considerable differences in the mechanical properties around the hoof capsule; transverse beams from the toe were 81% stiffer and 28% stronger than those from the heels. This corresponded with differences in the hydration of the hoof wall; beams from the toe had a lower water content (24.1±0.25%) than those from the heels (28.3±0.37%). Differences in the flexural properties are thought to be largely a result of variation in the water content. Mechanical data are further discussed in relation to variation in the structure and loading of the hoof wall
Regional variation in the microhardness and mineral content of porcine long bones
Pig carcasses are frequently used as models for the human cadaver in the study of trauma and wound patterns. Limited availability and ethical concerns over the use of human tissue has meant that porcine bone is often used as a substitute for human bone in such studies. However, there is a lack of comprehensive mechanical data to make informed decisions on the choice of model to account for variations in the age, sex and body mass.
In this study, variation in the properties of cortical bone along the length of the porcine humerus and ulna, from five female pigs aged over 36 months, was investigated by using Vickers microhardness tests. Transverse sections were taken from the proximal, mid and distal regions of the diaphyses, and tests were carried out in the anterior, medial, posterior, and lateral quadrants. Microhardness was also measured across the cortex from the periosteal to endosteal surfaces. Regional variation in mineral content was explored by analysing samples, taken immediately adjacent to the hardness tests, using Atomic Absorption Spectroscopy.
Mechanical data are discussed in relation to mineral content, morphology and loading of the limbs, within a forensic context
Since devolution, policymaking in Scotland has been profoundly conservative
Scotland has been largely self-governing in major areas such as health, education and local government since devolution in 1999. All types of policy innovation were promised with devolution and are promised by advocates of independence. In this context it is salutary to reflect that the overall record of the Scottish Government and the Scottish Parliament in these major policy areas in the decade and a half of their current existence is, with a few exceptions, conservative, argues Norman Bonney
What happens if Scotland votes ‘Yes’ in the independence referendum?
Scotland will hold an independence referendum on 18 September, but what would actually happen if voters opted to back independence from the UK? Norman Bonney assesses how the Scottish and UK governments would seek to negotiate Scotland’s independence, noting that the task would be far from straightforward
Implications of the Information Technology Revolution for People with Disabilities
The paper focuses on opportunities for the integration of persons with different types of disabilities in the information technology (IT) labour market. Recent IT developments are identified and examined for their potentially harmful or beneficial effects on access to the IT labour market for persons with disabilities. The opportunities created by new job creation, new forms of training, teleworking, and the role of assistive technologies in facilitating workplace accommodations are briefly described. The focus is on new options for the design and implementation of computer-related assistive technologies in the workplace, and the impact of teleworking and the World Wide Web on employability and work-related training of persons with disabilities. The paper closes with a brief discussion of the roles that government agencies, business firms, labour unions, non-governmental organisations and education can play to help people with disabilities join the IT revolution and share its benefits
If implemented in full, the Smith Commission report will provide Scotland with a welcome range of new powers
The Smith Commission which looked at future options for the governance of Scotland in the post referendum landscape. Norman Bonney assesses the document, looking at its proposals on local governance, Air Passenger Duty, the continuing UK framework, and the new respective roles of the Scottish Parliament and Government, concluding that the range of powers offered are welcome and appropriate
Black Americans still face significant challenges, but President Obama can provide a model for wider social and electoral success
Almost half a century ago, Norman Bonney arrived from the UK for graduate study in sociology at the University of Chicago. The picture of the deeply embedded African-American disadvantage in US society that he developed then has only been confirmed by the passage of time. While systemic issues show little prospect of changing, Barack Obama could be a very important role model for black Americans seeking to achieve more involvement in the wider American society
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