390 research outputs found

    Analyzing and Resolving Issues in Software Project Risk Management

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    In last decade the main reason for projects failure is poormanagement of software. But now a day’s most of the organizations arefocusing on software project management for making project successful.Software project management provides overall management of softwarefrom project planning phase to project execution. In software projectmanagement we also deal with risks that may occur during developmentof projects. In this paper we analyze risks during management ofsoftware and we resolve issues that come in software project riskmanagement. We introduce some approaches by which we can resolveall the issues regarding software risk management. Risk managementalso suggests us that how we can avoid risks and if risks occur then howwe can control those risks. By analyzing software risk management, wecome to know that what factors affect risk management and how we canremove them. Software risk management manages all risks efficientlyand makes our project successful

    Body mass index and use of healthcare services in children: analyses from the Born in Bradford cohort study

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    The prevalence of childhood obesity in the UK is among the highest in Europe, but it is not well-known how childhood obesity affects the health of children from different ethnic backgrounds and what burden it carries for healthcare systems in childhood. South Asian people in the UK are shown to have a higher risk of obesity-associated diseases and their patterns of healthcare utilisation vary from that of White British people mostly due to different health-seeking behaviours and barriers to healthcare access. In this thesis, I explored the utilisation of primary and secondary healthcare services and associated healthcare costs by children’s weight status in a multi-ethnic birth cohort and investigated potential effect modification by ethnicity. I conducted a systematic-review and meta-analysis of the association between children’s weight status and healthcare utilisation. This informed analyses of the Born in Bradford (BiB) cohort with linked primary and secondary healthcare data, which enabled analyses of healthcare utilisation and costs by children’s weight status and ethnicity using negative binomial regression models. The prevalence of obesity was 10.1% in Pakistani children and 9.9% in White British children, the two main ethnic groups in the BiB cohort. In the cohort analyses: obese children had significantly higher rates and costs of primary care consultations, primary care prescriptions and A&E visits, when compared to normal weight children. There was no effect modification by ethnicity, however independent of weight status, Pakistani children had significantly higher rates and costs compared to White British children across all measures of healthcare utilisation. This thesis suggests that childhood obesity results in higher utilisation and costs of primary and secondary healthcare services during primary school years, indicative of higher clinical need and poor health in obese children compared to normal weight children. The findings highlight the importance of implementing effective childhood obesity interventions and prevention strategies that are tailored to the specific needs of a multi-ethnic population

    Improved Software Requirement process for Software Industries

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    In the software system development, requirement engineering plays a great role because system successfulness depends on it. If the requirements are clear and unambiguous in every aspect then the system will be developed error free. A number of clients that are not educated and illiterate, then in this scenario, the given requirements are not clear and full of ambiguous. In this paper, we proposed a method to resolve this problem in the shape of break the requirements, filter it (separate the necessary and un-necessary requirements), break into little bits, numbering them and prioritize them, after it is documented, the requirement that is very helpful for current and future changing in software system and finally shift to the development team for develop the project. We will apply this proposed method on case study as experimental to find out the definite and relevant results

    Future Computing: DNA Hard Drives

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    DNA is a hard drive, the memory in every cell of every living organism that has the instructions on how to make that cell. With the exponential growth of our media, the growth of data storage is also increasing. DNA is incredible compact due to its molecular structure and can be used to achieve data attractively through genome sequencing. A raw limit of 1 Exabyte/mm3 (109 GB/mm3) having half-life of over 500 years. With this, all the data of the world can be stored in just a small place of a room

    Ambient Intelligence

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    Ambient intelligence is electronic environment which are sensitive to the presence of people. It is the light of future technologies. All AMI subsystems are interact with each other to accomplish their goal. AMI applications which are directly interact to define the environment. It shows that human environment which are not produced this process. The AMI systems should identify the various emotions of human experience. The AMI systems can also highlight the communication of the user. The AMI systems which is consists of robots and sensors

    Vehicular Data Cloud Services

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    The advance cloud computing has provided an opportunity to resolve the challenges which effects by increasing transportation issues. Two methods of cloud services are available these are parking and mining. Mobile cloud computing has improved the storage capacity, stand by time of mobile terminals by migrating data processing to the remote cloud. The introduction of smart phones, cloud computing the automotive system is shifting toward the internet of vehicles

    Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties

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    Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population. Currently, it is unclear whether advanced donor age and commonly associated comorbidities affect the properties of ex vivo-expanded BMSCs. Thus, we stratified cells from adult and elderly donors from our biobank (n = 10 and n = 13, mean age 38 and 72 years, respectively) and compared their phenotypic and functional performance, using multiple assays typically employed as minimal criteria for defining multipotent mesenchymal stromal cells (MSCs). We found that BMSCs from both cohorts meet the standard criteria for MSC, exhibiting similar morphology, growth kinetics, gene expression profiles, and pro-angiogenic and immunosuppressive potential and the capacity to differentiate toward adipogenic, chondrogenic, and osteogenic lineages. We found no substantial differences between cells from the adult and elderly cohorts. As positive controls, we studied the impact of in vitro aging and inflammatory cytokine stimulation. Both conditions clearly affected the cellular properties, independent of donor age. We conclude that in vitro aging rather than in vivo donor aging influences BMSC characteristics

    Global genetic diversity and evolutionary patterns among Potato leafroll virus populations

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    Potato leafroll virus (PLRV) is a widespread and one of the most damaging viral pathogens causing significant quantitative and qualitative losses in potato worldwide. The current knowledge of the geographical distribution, standing genetic diversity and the evolutionary patterns existing among global PLRV populations is limited. Here, we employed several bioinformatics tools and comprehensively analyzed the diversity, genomic variability, and the dynamics of key evolutionary factors governing the global spread of this viral pathogen. To date, a total of 84 full-genomic sequences of PLRV isolates have been reported from 22 countries with most genomes documented from Kenya. Among all PLRV-encoded major proteins, RTD and P0 displayed the highest level of nucleotide variability. The highest percentage of mutations were associated with RTD (38.81%) and P1 (31.66%) in the coding sequences. We detected a total of 10 significantly supported recombination events while the most frequently detected ones were associated with PLRV genome sequences reported from Kenya. Notably, the distribution patterns of recombination breakpoints across different genomic regions of PLRV isolates remained variable. Further analysis revealed that with exception of a few positively selected codons, a major part of the PLRV genome is evolving under strong purifying selection. Protein disorder prediction analysis revealed that CP-RTD had the highest percentage (48%) of disordered amino acids and the majority (27%) of disordered residues were positioned at the C-terminus. These findings will extend our current knowledge of the PLRV geographical prevalence, genetic diversity, and evolutionary factors that are presumably shaping the global spread and successful adaptation of PLRV as a destructive potato pathogen to geographically isolated regions of the world

    Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

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    Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

    Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

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    One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI
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