38 research outputs found
Complete (O_7,O_8) contribution to B -> X_s gamma at order alpha_s^2
We calculate the set of O(alpha_s^2) corrections to the branching ratio and
to the photon energy spectrum of the decay process B -> X_s gamma originating
from the interference of diagrams involving the electromagnetic dipole operator
O_7 with diagrams involving the chromomagnetic dipole operator O_8. The
corrections evaluated here are one of the elements needed to complete the
calculations of the B -> X_s gamma branching ratio at next-to-next-to-leading
order in QCD. We conclude that this set of corrections does not change the
central value of the Standard Model prediction for Br(B -> X_s gamma) by more
than 1 %.Comment: 19 pages, 8 figure
Updated NNLO QCD predictions for the weak radiative B-meson decays
Weak radiative decays of the B mesons belong to the most important flavor
changing processes that provide constraints on physics at the TeV scale. In the
derivation of such constraints, accurate standard model predictions for the
inclusive branching ratios play a crucial role. In the current Letter we
present an update of these predictions, incorporating all our results for the
O(alpha_s^2) and lower-order perturbative corrections that have been calculated
after 2006. New estimates of nonperturbative effects are taken into account,
too. For the CP- and isospin-averaged branching ratios, we find B_{s gamma} =
(3.36 +_ 0.23) * 10^-4 and B_{d gamma} = 1.73^{+0.12}_{-0.22} * 10^-5, for
E_gamma > 1.6GeV. Both results remain in agreement with the current
experimental averages. Normalizing their sum to the inclusive semileptonic
branching ratio, we obtain R_gamma = ( B_{s gamma} + B_{d gamma})/B_{c l nu} =
(3.31 +_ 0.22) * 10^-3. A new bound from B_{s gamma} on the charged Higgs boson
mass in the two-Higgs-doublet-model II reads M_{H^+} > 480 GeV at 95%C.L.Comment: journal version, 5 pages, no figure
Magnetic dipole operator contributions to the photon energy spectrum in anti-B -> X(s) gamma at O(alpha(s)^2)
We compute the O(\alpha_s^2) contributions to the photon energy spectrum of
the inclusive decay \bar{B} -> X_s \gamma associated with the magnetic penguin
operator O_7. They are an essential part of the ongoing NNLO calculation of
this important decay. We use two different methods to evaluate the master
integrals, one based on the differential equation approach and the other on
sector decomposition, leading to identical results which in turn agree with
those of a recent independent calculation by Melnikov and Mitov. We study the
numerical relevance of this set of NNLO contributions in the photon energy
spectrum and discuss the change of bottom quark mass scheme.Comment: 18 pages, uses axodraw.st
NNLL QCD Contribution of the Electromagnetic Dipole Operator to Gamma(anti-B -> X(s) gamma)
We present an independent calculation of that part of the O(\alpha_s^2)
contribution to the decay width \Gamma(\bar B -> X_s \gamma) which arises from
the self-interference term of the electromagnetic dipole operator O_7. Using a
different method, we find complete agreement with a previous calculation. This
NNLL contribution is an important ingredient for the complete NNLL prediction
of \Gamma(\bar B -> X_s \gamma) which will resolve the charm quark mass
ambiguity appearing at NLL accuracy.Comment: 15 pages, uses axodraw.st
Analysis of Neutral Higgs-Boson Contributions to the Decays B_s -> l^+l^- and B -> K l^+l^-
We report on a calculation of Higgs-boson contributions to the decays B_s ->
l^+l^- and B -> K l^+l^- (l=e, mu) which are governed by the effective
Hamiltonian describing b -> s l^+ l^-. Compact formulae for the Wilson
coefficients are provided in the context of the type-II two-Higgs-doublet model
(2HDM) and supersymmetry (SUSY) with minimal flavour violation, focusing on the
case of large tan(beta). We derive, in a model-independent way, constraints on
Higgs-boson-mediated interactions, using present experimental results on rare B
decays including b -> s gamma, B_s -> mu^+ mu^-, and B -> K^(*) mu^+ mu^-. In
particular, we assess the impact of possible scalar and pseudoscalar
interactions transcending the standard model (SM) on the branching ratio of B_s
-> mu^+ mu^- and the forward-backward (FB) asymmetry of mu^- in B -> K mu^+
mu^- decay. We find that the average FB asymmetry, which is unobservably small
within the SM, and therefore a potentially valuable tool to search for new
physics, is predicted to be no greater than 4% for a nominal branching ratio of
about 6x10^{-7}. Moreover, striking effects on the decay spectrum of B -> K
mu^+ mu^- are already ruled out by experimental data on the B_s -> mu^+ mu^-
branching fraction. In addition, we study the constraints on the parameter
space of the 2HDM and SUSY with minimal flavour violation. While the type-II
2HDM does not give any sizable contributions to the above decay modes, we find
that SUSY contributions obeying the constraint on b -> s gamma can affect
significantly the branching ratio of B_s -> mu^+ mu^-. We also comment on
previous calculations contained in the literature.Comment: 29 pages, REVTeX, 8 figures. Minor corrections in Eqs. (5.4), (5.11)
and (6.3) of the published versio
Charm quark mass dependence of the electromagnetic dipole operator contribution to anti-B -> X(s) gamma at O(alpha**2(s))
We extend existing calculations of the electromagnetic dipole operator
contribution to the total decay rate and the photon energy spectrum of the
decay \bar{B} -> X_s\gamma at O(\alpha_s^2) by working out the exact dependence
on the charm quark mass.Comment: 10 pages, uses axodraw.sty; minor corrections, references added,
matches published versio
β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance
Beta-catenin plays an important role in embryogenesis and carcinogenesis by controlling either cadherin-mediated cell adhesion or transcriptional activation of target gene expression. In many types of cancers nuclear translocation of beta-catenin has been observed. Our data indicate that during melanoma progression an increased dependency on the transcriptional function of beta-catenin takes place. Blockade of beta-catenin in metastatic melanoma cell lines efficiently induces apoptosis, inhibits proliferation, migration and invasion in monolayer and 3-dimensional skin reconstructs and decreases chemoresistance. In addition, subcutaneous melanoma growth in SCID mice was almost completely inhibited by an inducible beta-catenin knockdown. In contrast, the survival of benign melanocytes and primary melanoma cell lines was less affected by beta-catenin depletion. However, enhanced expression of beta-catenin in primary melanoma cell lines increased invasive capacity in vitro and tumor growth in the SCID mouse model. These data suggest that beta-catenin is an essential survival factor for metastatic melanoma cells, whereas it is dispensable for the survival of benign melanocytes and primary, non-invasive melanoma cells. Furthermore, beta-catenin increases tumorigenicity of primary melanoma cell lines. The differential requirements for beta-catenin signaling in aggressive melanoma versus benign melanocytic cells make beta-catenin a possible new target in melanoma therapy
A systematic review of high-fibre dietary therapy in diverticular disease
The exact pathogenesis of diverticular disease of the sigmoid colon is not well established. However, the hypothesis that a low-fibre diet may result in diverticulosis and a high-fibre diet will prevent symptoms or complications of diverticular disease is widely accepted. The aim of this review is to assess whether a high-fibre diet can improve symptoms and/or prevent complications of diverticular disease of the sigmoid colon and/or prevent recurrent diverticulitis after a primary episode. Clinical studies were eligible for inclusion if they assessed the treatment of diverticular disease or the prevention of recurrent diverticulitis with a high-fibre diet. The following exclusion criteria were used for study selection: studies without comparison of the patient group with a control group. No studies concerning prevention of recurrent diverticulitis with a high-fibre diet met our inclusion criteria. Three randomised controlled trials (RCT) and one case-control study were included in this systematic review. One RCT of moderate quality showed no difference in the primary endpoints. A second RCT of moderate quality and the case-control study found a significant difference in favour of a high-fibre diet in the treatment of symptomatic diverticular disease. The third RCT of moderate quality found a significant difference in favour of methylcellulose (fibre supplement). This study also showed a placebo effect. High-quality evidence for a high-fibre diet in the treatment of diverticular disease is lacking, and most recommendations are based on inconsistent level 2 and mostly level 3 evidence. Nevertheless, high-fibre diet is still recommended in several guideline
The Physics of the B Factories
This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C