10 research outputs found
Biopreservation of hepatocytes: current concepts on hypothermic preservation, cryopreservation, and vitrification
Isolated liver cells (primarily isolated hepatocytes) have found important applications in science and medicine over the past 40 years in a wide range of areas, including physiological studies, investigations on liver metabolism, organ preservation and drug de-toxification, experimental and clinical transplantation. An integral component of many of these works is the need to store the isolated cells, either for short or long-term periods. This review covers the biopreservation of liver cells, with a focus on the history of liver cell biopreservation, the application of hypothermia for short-term storage, standard cryopreservation methods for isolated hepatocytes, the biopreservation of other types of liver cells, and recent developments such as vitrification of hepatocytes. By understanding the basis for the different approaches, it will be possible to select the best options for liver cell biopreservation in different applications, and identify ways to improve preservation protocols for the future.Fil: Fuller, Barry J.. University College London; Estados UnidosFil: Petrenko, Alexander Y.. Ukraine Academy of Sciences; UcraniaFil: Rodriguez, Joaquin Valentin. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Rosario; Argentina. Universidad Nacional de Rosario. Secretaria de Ciencia y TĂ©cnica. Centro Binacional de InvestigaciĂłn en CriobiologĂa ClĂnica y Aplicada; ArgentinaFil: Somov, Alexander Y.. Ukraine Academy of Sciences; UcraniaFil: Balaban, Cecilia LucĂa. Universidad Nacional de Rosario. Secretaria de Ciencia y TĂ©cnica. Centro Binacional de InvestigaciĂłn en CriobiologĂa ClĂnica y Aplicada; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Rosario; ArgentinaFil: Guibert, Edgardo Elvio. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Rosario; Argentina. Universidad Nacional de Rosario. Secretaria de Ciencia y TĂ©cnica. Centro Binacional de InvestigaciĂłn en CriobiologĂa ClĂnica y Aplicada; Argentin
The Physics of the B Factories
This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C
An Observational Overview of Solar Flares
We present an overview of solar flares and associated phenomena, drawing upon
a wide range of observational data primarily from the RHESSI era. Following an
introductory discussion and overview of the status of observational
capabilities, the article is split into topical sections which deal with
different areas of flare phenomena (footpoints and ribbons, coronal sources,
relationship to coronal mass ejections) and their interconnections. We also
discuss flare soft X-ray spectroscopy and the energetics of the process. The
emphasis is to describe the observations from multiple points of view, while
bearing in mind the models that link them to each other and to theory. The
present theoretical and observational understanding of solar flares is far from
complete, so we conclude with a brief discussion of models, and a list of
missing but important observations.Comment: This is an article for a monograph on the physics of solar flares,
inspired by RHESSI observations. The individual articles are to appear in
Space Science Reviews (2011
Biopreservation of Hepatocytes: Current Concepts on Hypothermic Preservation, Cryopreservation, And Vitrification
Isolated liver cells (primarily isolated hepatocytes) have found important applications in science and medicine over the past 40 years in a wide range of areas, including physiological studies, investigations on liver metabolism, organ preservation and drug de-toxification, experimental and clinical transplantation. An integral component of many of these works is the need to store the isolated cells, either for short or long-term periods. This review covers the biopreservation of liver cells, with a focus on the history of liver cell biopreservation, the application of hypothermia for short-term storage, standard cryopreservation methods for isolated hepatocytes, the biopreservation of other types of liver cells, and recent developments such as vitrification of hepatocytes. By understanding the basis for the different approaches, it will be possible to select the best options for liver cell biopreservation in different applications, and identify ways to improve preservation protocols for the future.Fil: Fuller, Barry J.. University College London; Estados UnidosFil: Petrenko, Alexander Y.. Ukraine Academy of Sciences; UcraniaFil: Rodriguez, Joaquin Valentin. Universidad Nacional de Rosario. Secretaria de Ciencia y Tecnica. Centro Binacional de InvestigaciĂłn en Criobiologia Clinica y Aplicada; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; ArgentinaFil: Somov, Alexander Y.. Ukraine Academy of Sciences; UcraniaFil: Balaban, Cecilia LucĂa. Universidad Nacional de Rosario. Secretaria de Ciencia y Tecnica. Centro Binacional de InvestigaciĂłn en Criobiologia Clinica y Aplicada; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; ArgentinaFil: Guibert, Edgardo Elvio. Universidad Nacional de Rosario. Secretaria de Ciencia y Tecnica. Centro Binacional de InvestigaciĂłn en Criobiologia Clinica y Aplicada; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; Argentin
First observation of the decay B0sâÏKÂŻâ0
The first observation of the decay B0sâÏKÂŻÂŻÂŻâ0 is reported. The analysis is based on a data sample corresponding to an integrated luminosity of 1.0 fbâ1 of pp collisions at sâ=7 TeV, collected with the LHCb detector. A yield of 30 ± 6 B0sâ(K+Kâ)(KâÏ+) decays is found in the mass windows 1012.5 < M (K + K â) < 1026.5 MeV/c 2 and 746 < M(K â Ï +) < 1046 MeV/c 2. The signal yield is found to be dominated by B0sâÏKÂŻÂŻÂŻâ0 decays, and the corresponding branching fraction is measured to be B(B0sâÏKÂŻÂŻÂŻâ0) = (1.10 ± 0.24 (stat) ± 0.14 (syst) ± 0.08 (f d /f s )) Ă 10â6, where the uncertainties are statistical, systematic and from the ratio of fragmentation fractions f d /f s which accounts for the different production rate of B 0 and B0s mesons. The significance of B0sâÏKÂŻÂŻÂŻâ0 signal is 6.1 standard deviations. The fraction of longitudinal polarization in B0sâÏKÂŻÂŻÂŻâ0 decays is found to be f 0 = 0.51 ± 0.15 (stat) ± 0.07 (syst)