Estruturação das práticas religiosas diárias

The article is devoted to the study of religious practices. One of the characteristic features of development of religious studies in Russia is concentration on local religious practices similar to anthropological researches of the second half of the ХХ century. At the same time there is no conceptualization of present cases, only special theories of the case are formed, whereas the explanatory models is not established. This actualizes the need for the development of a conceptual and methodological framework to study the problems associated with the daily religious practices. On the background of evident demand for conceptual analysis of forming modern daily religious practices we think it is necessary to reveal general principles of their structuring in the context of everyday life.El artículo está dedicado al estudio de las prácticas religiosas. Una de las características del desarrollo de los estudios religiosos en Rusia es la concentración en prácticas religiosas locales similares a las investigaciones antropológicas de la segunda mitad del siglo. Al mismo tiempo, no hay una conceptualización de los casos presentes, solo se forman teorías especiales del caso, mientras que los modelos explicativos no están establecidos. Esto actualiza la necesidad del desarrollo de un marco conceptual y metodológico para estudiar los problemas asociados con las prácticas religiosas diarias. En el contexto de la demanda evidente de análisis conceptual de la formación de prácticas religiosas diarias, creemos que es necesario revelar los principios generales de su estructuración en el contexto de la vida cotidiana.O artigo é dedicado ao estudo das práticas religiosas. Uma das características do desenvolvimento dos estudos religiosos na Rússia é a concentração em práticas religiosas locais semelhantes às pesquisas antropológicas da segunda metade do século XX. Ao mesmo tempo, não há conceituação de casos presentes, apenas teorias especiais do caso são formadas, enquanto os modelos explicativos não são estabelecidos. Isso atualiza a necessidade do desenvolvimento de uma estrutura conceitual e metodológica para estudar os problemas associados às práticas religiosas cotidianas. No contexto de uma demanda evidente por uma análise conceitual da formação de práticas religiosas cotidianas modernas, pensamos que é necessário revelar princípios gerais de sua estruturação no contexto da vida cotidiana

Duodenal Eosinophilia in Functional Dyspepsia

Aim: to present observation of a patient diagnosed with functional dyspepsia based on current guidelines, and having increased eosinophil counts in the biopsy specimen of duodenal mucosa. To consider possible causes of duodenal eosinophilia in the light of present-day concepts.Highlights. Patient K., 40 years old, complained of dyspeptic phenomena, the first appearance of which she had noted at the age of 18. The patient noted poor tolerance to canned and fermented foods, which provoked an increase in dyspepsia and sometimes caused watery diarrhea. The examination excluded “symptoms of concern”. Successful antihelicobacter eradication therapy was carried out. Morphological examination of the stomach showed phenomena of mild chronic inflammation without intestinal metaplasia or glandular atrophy. A biopsy of the mucosa of the descending part of the duodenum showed a moderate increase in the levels of mononuclears and eosinophils in its lamina propria without penetration into the epithelium of the villi or formation of clusters. The patient suffers from pollinosis; sensitization to birch pollen was diagnosed by a skin prick test. However, she has no oral allergy symptoms, which does not allow linking duodenal eosinophilia to food allergy. Based on current guidelines, the patient was diagnosed with functional dyspepsia. In addition to dietary restrictions, treatment courses with a proton pump inhibitor, itopride, and S-methylmethionine sulfonium chloride, which has an antihistamine effect, were recommended for periods of worsening dyspepsia.Conclusion. The clinical significance of duodenal eosinophilia and local histamine production in patients with a clinical diagnosis of functional dyspepsia deserves special attention. Triggering factors provoking the worsening of symptoms should be analyzed; in particular, a food diary and exclusion of food allergies are recommended. Histamine-neutralizing drugs may play a role in the treatment of FD with duodenal eosinophilia in the future

ИФЛА и ЦУР: обзор проектов Секции окружающей среды, устойчивого развития и библиотек

Among the other IFLA sections and thematic groups, IFLA Environment, Sustainability and Libraries Section (ENSULIB) is in the thick of sustainability problems and, in particular, of ecological component of the Sustainable Development Goals (SDG). ENSULIB encourages the libraries to inspire their communities for the ecologically sustainable course of action through providing materials on “green” librarianship, giving the floor to “green” librarians and library projects, by taking the lead and propounding the discussion.On IFLA ENSULIB web page, one can find materials and projects for the libraries working in ecological education and advocating sustainability ideas, and among these initiatives are IFLA Green Library Award, news bulletin, open access thematic information resource, Library Map of the World Project, and regular webinars. The ENSULIB provides support to zero-waste and decrease-ofconsumption projects. The authors discuss the materials that might be useful for Russian libraries.Среди множества секций и тематических групп Международной федерации библиотечных ассоциаций (ИФЛА) наиболее плотно вопросами устойчивого развития, а особенно вопросами, связанными с экологической составляющей Целей устойчивого развития (ЦУР), занимается Секция окружающей среды, устойчивого развития и библиотек (Environment, Sustainability and Libraries Section – ENSULIB). Деятельность ENSULIB направлена на то, чтобы библиотекари вдохновляли свои сообщества на более экологически устойчивый образ действий, предоставляя материалы по «зелёному библиотечному делу», давая слово «зелёным библиотекарям и библиотечным проектам», подавая пример и предлагая обсуждение этих вопросов.На тематической странице секции на сайте ИФЛА представлено множество материалов и проектов для библиотек, работающих в области экологического просвещения и продвижения идей устойчивого развития. Среди них: премия ИФЛА «Зелёная библиотека», информационный бюллетень, общедоступный тематический информационный ресурс, проект «Библиотечная карта», регулярные вебинары. Оказана поддержка проектам, призванным сократить выбросы и снизить уровень потребления. В статье освещены материалы, которые могут быть использованы в деятельности российских библиотек

ФУНКЦИОНАЛЬНЫЙ ПОТЕНЦИАЛ КЛЕТОК ПАМЯТИ CD8+ В УСЛОВИЯХ ЛИМФОПЕНИИ, ВЫЗВАННОЙ ВВЕДЕНИЕМ ГИДРОКОРТИЗОНА

Background. Wide use of glucocorticoids therapy for neoplasms, autoimmune diseases and allergies is associated with suppression of adaptive immunity that requires profound study of their immunoregulatory properties and immunotoxicity.Results. In this work, using our model of selective activation of mouse CD8+ memory cells in the mixed lymphocyte reaction (MLR) in vitro, we show for the first time that intraperitoneal injection of high dose hydrocortisone (2.5 mg per animal) allows to detect memory cells in the thymus of animals immunized with allogeneic tumor cells. Similar to memory cells from other lymphoid organs, hydrocortisone-resistant thymic lymphocytes from immune animals respond on allogeneic stimulators subjected to severe heat shock and are immunologically specific to immunizing alloantigen. Thus, cortisone-resistant thymocytes are partially or completely represented by memory cells. We also show here that memory responses of heterozygotes on TCR a-chain knock-out (genetically incapable to secondary rearrangement of TCR achains) are significantly enhanced as compared with the ones of wild type mice.Conclusion. These findings allows to suggest the hypothesis according to which memory T cell clones proliferating in primary immune response migrate into thymus providing necessary microenvironment for reexpression of recombinases. After editing of genes encoding TCR achains, such T lymphocytes can return to peripheral repertoire maintaining its wideness.Введение. Широкое применение глюкокортикоидов в терапии онкологических, аутоиммунных и аллергических заболеваний сопряжено с подавлением функций адаптивного иммунитета и ставит задачу углубленного исследования их иммунорегуляторных свойств и иммунотоксичности.Результаты. Используя разработанную нами модель селективной активации мышиных клеток памяти CD8+ в смешанной культуре лимфоцитов (mixedlymphocytereaction, MLR) invitro, в этой работе мы впервые показали, что внутрибрюшинное введение мышам гидрокортизона в высокой дозе (2,5 мг на 1 животное) позволяет обнаружить Т-клетки памяти в тимусе животных, иммунизированных клетками  аллогенной опухоли. Как и клетки  памяти из других лимфоидных органов, лимфоциты тимуса иммунных животных, резистентные к гидрокортизону, отвечают пролиферацией на аллогенные стимуляторы, подвергнутые острому тепловому шоку и иммунологически специфичны к иммунизирующему аллоантигену. Таким образом, кортизонрезистентные тимоциты частично или полностью представлены клетками памяти. Также мы показали, что у гетерозигот по нокауту α-цепи TCR (генетически неспособных ко вторичной реаранжировке α-цепей) ответы клеток памяти значительно усилены по сравнению с ответами клеток памяти мышей дикого типа.Заключение. Полученные данные позволяют выдвинуть гипотезу, согласно которой клоны Т-клеток памяти, размножившиеся в первичном иммунном ответе, мигрируют в тимус, обеспечивающий микроокружение, необходимое для реэкспрессии ими рекомбиназ. После завершения редактирования α-цепей TCR такие Т-лимфоциты могут вернуться в периферический репертуар, поддерживая его широту

Constraints on jet quenching in p-Pb collisions at root s(NN)=5.02 TeV measured by the event-activity dependence of semi-inclusive hadron-jet distributions

CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThe ALICE Collaboration reports the measurement of semi-inclusive distributions of charged-particle jets recoiling from a high-transverse momentum trigger hadron in p-Pb collisions at root s(NN) = 5.02TeV. Jets are reconstructed from charged-particle tracks using the anti-k(T) algorithm with resolution parameter R = 0.2 and 0.4. A data-driven statistical approach is used to correct the uncorrelated background jet yield. Recoil jet distributions are reported for jet transverse momentum 15 < p(T,jet)(ch) < 50 GeV/c and are compared in various intervals of p-Pb event activity, based on charged-particle multiplicity and zero-degree neutral energy in the forward (Pb-going) direction. The semi-inclusive observable is self-normalized and such comparisons do not require the interpretation of p-Pb event activity in terms of collision geometry, in contrast to inclusive jet observables. These measurements provide new constraints on the magnitude of jet quenching in small systems at the LHC. In p-Pb collisions with high event activity, the average medium-induced out-of-cone energy transport for jets with R = 0.4 and 15 < p(T,jet)(ch) < 50 GeV/c is measured to be less than 0.4 GeV/c at 90% confidence, which is over an order of magnitude smaller than a similar measurement for central Pb-Pb collisions at root s(NN) = 2.76 TeV. Comparison is made to theoretical calculations of jet quenching in small systems, and to inclusive jet measurements in p-Pb collisions selected by event activity at the LHC and in d-Au collisions at RHIC.78395113CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOSem informaçãoSem informaçãoSem informaçãoAgências de fomento estrangeiras apoiaram essa pesquisa, mais informações acesse artig

Transverse momentum spectra and nuclear modification factors of charged particles in pp, p-Pb and Pb-Pb collisions at the LHC

CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOWe report the measured transverse momentum (pT) spectra of primary charged particles from pp, p-Pb and Pb-Pb collisions at a center-of-mass energy p sNN = 5 : 02TeV in the kinematic range of 0 : 15 < pT < 50 GeV/c and jj < 0 : 8. A signi fi cant improvement of systematic uncertainties motivated the reanalysis of data in pp and Pb-Pb collisions at p sNN = 2 : 76TeV, as well as in p-Pb collisions at p sNN = 5 : 02TeV, which is also presented. Spectra from Pb-Pb collisions are presented in nine centrality intervals and are compared to a reference spectrum from pp collisions scaled by the number of binary nucleon-nucleon collisions. For central collisions, the pT spectra are suppressed by more than a factor of 7 around 6-7 GeV/c with a signi fi cant reduction in suppression towards higher momenta up to 30 GeV/c. The nuclear modi fi cation factor RpPb, constructed from the pp and p-Pb spectra measured at the same collision energy, is consistent with unity above 8 GeV/c. While the spectra in both pp and Pb-Pb collisions are substantially harder at p sNN = 5 : 02TeV compared to 2.76TeV, the nuclear modi fi cation factors show no signi fi cant collision energy dependence. The obtained results should provide further constraints on the parton energy loss calculations to determine the transport properties of the hot and dense QCD matter.11133CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOAgências de fomento estrangeiras apoiaram essa pesquisa, mais informações acesse artig

Measurement of Z(0)-boson production at large rapidities in Pb-Pb collisions at root s(NN)=5.02 TeV

The production of Z(0) bosons at large rapidities in Pb-Pb collisions at root s(NN) = 5.02 TeV is reported. Z(0) candidates are reconstructed in the dimuon decay channel (Z(0) -> mu(+) mu(-)), based on muons selected with pseudo-rapidity -4.0 20 GeV/c. The invariant yield and the nuclear modification factor, RAA, are presented as a function of rapidity and collision centrality. The value of R-AA for the 0-20% central Pb-Pb collisions is 0.67 +/- 0.11(stat.) +/- 0.03 (syst.) f 0.06(corr. syst.), exhibiting a deviation of 2.6 sigma from unity. The results are well-described by calculations that include nuclear modifications of the parton distribution functions, while the predictions using vacuum PDFs deviate from data by 2.3 sigma in the 0-90% centrality class and by 3 sigma in the 0-20% central collisions. (C) 2018 The Author(s). Published by Elsevier B.V.Peer reviewe