20 research outputs found

    Throughput analysis for cognitive radio networks with multiple primary users and imperfect spectrum sensing

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    In cognitive radio networks, the licensed frequency bands of the primary users (PUs) are available to the secondary user (SU) provided that they do not cause significant interference to the PUs. In this study, the authors analysed the normalised throughput of the SU with multiple PUs coexisting under any frequency division multiple access communication protocol. The authors consider a cognitive radio transmission where the frame structure consists of sensing and data transmission slots. In order to achieve the maximum normalised throughput of the SU and control the interference level to the legal PUs, the optimal frame length of the SU is found via simulation. In this context, a new analytical formula has been expressed for the achievable normalised throughput of SU with multiple PUs under prefect and imperfect spectrum sensing scenarios. Moreover, the impact of imperfect sensing, variable frame length of SU and the variable PU traffic loads, on the normalised throughput has been critically investigated. It has been shown that the analytical and simulation results are in perfect agreement. The authors analytical results are much useful to determine how to select the frame duration length subject to the parameters of cognitive radio network, such as network traffic load, achievable sensing accuracy and number of coexisting PUs

    Xanthine oxidase-derived reactive oxygen metabolites contribute to liver necrosis: protection by 4-hydroxypyrazolo[3,4-d]pyrimidine

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    AbstractXanthine oxidase (XO) generates reactive oxygen metabolites (ROM) as a by-product while catalyzing their reaction. The present study implicates these ROM in the pathogenesis of liver necrosis produced in rats by the intraperitoneal administration of thioacetamide (TAA; 400 mg/kg b.wt.). After 16 h of TAA administration, the activity of rat liver XO increased significantly compared to that of the control group. At the same time, the level of serum marker enzymes of liver necrosis (aminotransferases and alkaline phosphatase) and tissue malondialdehyde content also increased in TAA treated rats. Tissue malondialdehyde concentration is an indicator of lipid peroxidation and acts as a useful marker of oxidative damage. Pretreatment of rats with XO inhibitor (4-hydroxypyrazolo[3,4-d]pyrimidine; allopurinol (AP)) followed by TAA could lower the hepatotoxin-mediated rise in malondialdehyde level as well as the level of marker enzymes associated with liver necrosis. The survival rate also increased in rats given AP followed by the lethal dose of TAA. In either case, the effect of AP was dose-dependent. Results presented in the paper indicate that increased production of XO-derived ROM contributes to liver necrosis, which can be protected by AP

    Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

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    BACKGROUND: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. METHODS: The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specific mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in different components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. FINDINGS: Globally, 18·7% (95% uncertainty interval 18·4–19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2–59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5–49·6) to 70·5 years (70·1–70·8) for men and from 52·9 years (51·7–54·0) to 75·6 years (75·3–75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5–51·7) for men in the Central African Republic to 87·6 years (86·9–88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3–238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6–42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2–5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. INTERPRETATION: This analysis of age-sex-specific mortality shows that there are remarkably complex patterns in population mortality across countries. The findings of this study highlight global successes, such as the large decline in under-5 mortality, which reflects significant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing

    Narrowband beamforming algorithm for smart antenna arrays

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    The multidisciplinary field of smart antennas has become significantly important over the past two decades. In this paper constrained least mean square (CLMS) algorithm for narrowband adaptive beamforming has been derived. This algorithm is capable of efficiently adapting according to the environment and able to maintain the chosen frequency response in the look direction always while minimizing the output power of the array. The capability of the smart antenna systems to track the user with the main lobe and interference with the nulls creates a significant impact on the current and future wireless sensor networks. This paper includes the performance evaluation of the narrowband adaptive beamforming algorithm. The adaptability of the algorithm is closely observed for uniformly spaced linear array (ULA). The results are supported by various simulations environments created in MATLAB like varying the number of antenna arrays and varying inter element spacing between the array elements

    Machine learning classification of hermite gaussian beams for 5G and beyond free-space optical backhaul links

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    Free space optical (FSO) communication offers an excellent opportunity to develop energy-efficient, secure, and ultrafast data links for 5G and beyond applications, including heterogeneous networks with massive connectivity and wireless backhauls for cellular systems. However, the effect of an optical beam's pointing inaccuracy combined with the impact of climate factors must be considered in the FSO communication system. In this paper, we first evaluate the performance reliability and availability of NRZ-based mode division multiplexing (MDM)-FSO backhaul. In particular, a single wavelength laser is used to transmit four different optical beams, using four different wavelengths. It also explores and classifies four beams used for capacity enhancement in mode division multiplexed MDM-FSO backhaul links. Several Machine Learning (ML) models are used to classify the four optical modes. Results indicate successful transmission of 80 Gbps. Furthermore, the primary findings indicate that the ML model exhibits an impressive accuracy rate of approximately 97% in classifying four distinct beams

    Geometric Mean Detector for Spectrum Sensing

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    Energy efficient heterogeneous networks

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    Association of networked flying platforms with small cells for network centric 5G+ C-RAN

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    5G+ systems expect enhancement in data rate and coverage area under limited power constraint. Such requirements can be fulfilled by the densification of small cells (SCs). However, a major challenge is the management of fronthaul links connected to an ultra dense network of SCs. A cost effective and scalable idea of using network flying platforms (NFPs) is employed here, where the NFPs are used as fronthaul hubs that connect the SCs to the core network. The association problem of NFPs and SCs is formulated considering a number of practical constraints such as backhaul data rate limit, maximum supported links and bandwidth by NFPs and quality of service requirement of the system. The network centric case of the system is considered that aims to maximize the number of associated SCs without any biasing, i.e., no preference for high priority SCs. Then, two new efficient greedy algorithms are designed to solve the presented association problem. Numerical results show a favorable performance of our proposed methods in comparison to exhaustive search. 2017 IEEE.Scopu

    3-D Placement Schemes of Multiple UAVs in NFP-based Wireless Networks

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    In this paper, we propose two placement strategies of multiple unmanned aerial vehicles (UAVs) in network flying platform (NFP)-based wireless networks. The first strategy is based on a proposed distributed placement algorithm (DPA) that can be executed by the collaboration of the users and a high altitude controlling NFP (mother UAV). The second strategy uses a proposed centric placement algorithm (CPA) at the mother UAV to define the number and optimal placement of the needed UAVs. For the system model, a Matern Cluster Process (MCP) is used to describe the users' location in realistic scenarios. Based on that, we detail the proposed algorithms, and we derive the corresponding number expressions of the needed UAVs. Numerical results are used to confirm the derived expression and to evaluate the proposed 3-D placement strategies.This paper was made possible by NPRP grant 8-1545-2-657 from the Qatar National Research Fund (a member of Qatar Foundation), and the sponsorship agreement in support of research and collaboration by Ooredoo, Doha, Qatar.Scopu
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