21 research outputs found
Competências-chave na era digital para coaprendizagem e coinvestigação
- Publication venue
- LE@D
- Publication date
- 01/12/2013
- Field of study
Este trabalho visa apresentar uma investigação exploratória em desenvolvimento com resultados preliminares sobre “Competências-chave para educação do século XXI na Era Digital”. Utiliza-se a ciber-etnografia como método de observação assíncrona (fórum e wikis) e síncrona (webconferência) das competências e habilidades desenvolvidas durante o processo de co-investigação e coaprendizagem em dois espaços virtuais. Este estudo envolve pesquisadores do Reino Unido, Brasil, Portugal e Espanha que iniciaram suas interações no portal Encuentro.Educared do “Encontro Internacional de Educação 2012-2013”, realizado pela empresa Telefônica e também no ambiente de investigação weSPOT (Working Environment with Social, Personal and Open Technologies) financiado pela Comissão Européia. Como resultado deste trabalho, observou-se que o portal propiciou o desenvolvimento mais explicíto de literacias digitais, possivelmente por ser uma interface mais simples e familiar (fórum). E no ambiente de investigação, os participantes já com maior facilidade com tecnologias digitais tiveram maiores oportunidades de desenvolver outras competências relacionadas com a Literacia Científica.This paper presents an exploratory investigation in development with preliminary results on "Key Competences for XXI Century Education in the Digital Age." The method applied was cyber-ethnography with asynchronous observation (forum and wiki) and synchronous discussions (webconference) for analysing skills and competences developed during the process of co-inquiry and co-learning in two online areas. This study involves researchers from the UK, Brazil, Portugal and Spain. They initiated their interactions in the portal Encuentro.Educared of the "International Meeting on Education 2012-2013", organized by company Telefónica and also in the inquiry environment weSPOT (Working Environment with Social Personal and Open Technologies) funded by the European Commission. As a result of this study, it was observed that the portal led to the development of more explicit digital literacies, possibly because it was a simpler interface and familiar (forum). And in the inquiry environment, participants familiar with digital technologies had more opportunities to develop other skills related to Critical-Creative Thinking and Socio-Scientific Reasoning.Universidade Aberta; Pavilhão do Conhecimento; LEA
Federalismo e conflitos distributivos: disputa dos estados por recursos orçamentários federais
- Author
- AFONSO José Roberto
- AMES Barry
- AMES Barry
- ARRETCHE Marta
- BEZERRA Marcos
- BICKERS Kenneth
- BIRD Richard
- BLUMM Márcia H. N.
- BONFIM Washington L. S.
- BORGES André
- Celina Souza
- DESPOSATO Scott
- ELWOOD John
- FIGUEIREDO Argelina
- FIGUEIREDO Argelina
- FRANCO Gustavo
- GALVÃO Antonio Carlos
- GONDIM Linda M. de P.
- IMMERGUT Ellen
- KUGELMAS Eduardo
- MEDEIROS Antônio Carlos de
- NASCIMENTO Vânia B. do.
- NICOLAU Jairo
- OLIVEIRA Nelson de
- PEREIRA Carlos
- PINHEIRO Vinicius C.
- REGO Antônio C. Pojo do.
- SAMUELS David J.
- SANTOS Fabiano
- SANTOS Maria Helena de C.
- SCHNEIDER Aaron
- SERRA José
- SHAH Anwar
- SHEPSLE K.
- SOUZA Celina
- SOUZA Celina
- SOUZA Celina
- TENDLER Judith
- TSEBELIS George
- WEAVER Kent R.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2003
- Field of study
SINGULARIDADES NO PROCESSO DE TRABALHO ENTRE TÉCNICOS EM SAÚDE BUCAL E CIRURGIÕES-DENTISTAS
- Author
- AGAMBEN Giorgio
- BACKES Dirce S.
- BARDIN Laurence
- BOURDIEU Pierre
- BOURDIEU Pierre
- CARVALHO Cristiana L.
- CAVALCANTE FILHO João B.
- CHAVES Mario
- CRUZ NETO Otávio
- D'AMOUR Danielle
- DEJOURS Jacques C.
- EMMERICH Adauto
- EMMERICH Adauto
- ESPOSTI Carolina D. D.
- FARIAS Luís O.
- FERRETTI Celso J.
- FLEURI Reinaldo M.
- FOUCAULT Michel
- FRAZÃO Paulo
- FRAZÃO Paulo
- FRAZÃO Paulo
- FREIRE Paulo
- HALL Pippa
- LATOUR Bruno
- MALORY Thomas
- MERHY Emerson E.
- MINAYO Maria C. S.
- MORIN Edgar
- NARVAI Paulo C.
- OLIVEIRA Adriano
- PARANHOS Luiz R.
- PEDROSA José I. S.
- PEREIRA Antônio C.
- PEZZATO Luciane M.
- PUCCA JR. Gilberto A.
- RICHARDSON Roberto J.
- SAN MARTÍN-RODRÍGUEZ Leticia
- SCHRAIBER Lilia B.
- SERRA Mônica C.
- TEIXEIRA Ricardo R.
- ZANETTI Carlo H. G.
- ZANETTI Carlo H. G.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aisa Tharwat M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
- Akyol Onat O.
- Al Dorzi Hasan M.
- Al Jabbary Ahmed S.
- Albaiceta Guillermo M.
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain U.
- Allan Russell M.
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier G.
- Altaf Wahid
- Alvarez António M.
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Abdellatif Benslama Mourad
- An Youzhong
- Andersen Finn H.
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo M.
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Araujo Ana M.
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E.
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio C.
- Bailey Irene M.
- Bailey Mathew B.
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M.
- Barberet Guillaume
- Baron Rebecca M.
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros Filipa M.
- Barros Nelson C.
- Batra Hitesh
- Battle Ceri E.
- Bauer Philippe R.
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu H.
- Beegle Scott H.
- Beitler Jeremy R.
- Bellani Giacomo
- Bellani Giacomo
- Beloncle Francois
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien L.
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
- Biondi Rodrigo S.
- Biscione Roberto R.
- Bisso Mariano Carboni
- Black Colin S.
- Blakeman Thomas C.
- Bolon Stefan
- Borello Silvina A.
- Borotto Erika E.
- Botteri Marco
- Bouchoucha Slaheddine
- Boukhazna Messabi
- Bouw Maria J.
- Boyd Owen
- Bramall Jon
- Braschi Antonio
- Brazzi Luca
- Breen Dorothy M.
- Briquet Anais
- Brito Vania A.
- Brizuela Matias
- Brochard Laurent
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- Browne Troy S.
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- Burtenshaw Andrew J.
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- Camsooksai Julie
- Canestrini Sergio
- Cani Alma
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- Cardonnet Luis P.
- Careless Jon P.
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- Carteaux Guillaume
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- Castro Alejandro G.
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- Catorze Nuno T.
- Cazorla-Barranquero Francisca G.
- Ceniceros-Barros Alexandra
- Cereijo Enrique
- Cerny Vladimir
- Cerrato Valeria I.
- Cervantes Mavy Ramirez
- Cesar Palazon Sanchez
- Ceunen Helga
- Ceylan Ilkay
- Chabanne Russell
- Chapman Rhiannon
- Chau Simon K.
- Chelly Jonathan
- Chen Kai
- Chena Ariel
- Cheng Meisy Perez
- Chiche Jean-Daniel
- Chouchene Imed
- Choudry Shazia
- Christiansen Aage
- Cimic Nedim
- Cinnella Gilda
- Cirone Rob
- Citalán Johanna E.
- Claraco-Vega Luis M.
- Clarkson Kevin
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- Claverias Laura
- Cohen Jason E.
- Cole Jade M.
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- Cranshaw Julius H.
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- Curley Gerard
- Curto Elena Gallego
- Daldin Julio
- Dangers Laurence
- Danin Pierre-Eric
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- Davies Kyle G.
- Dawson Heidi
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- de Gordoa Laura Ortiz-Ruiz
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- Dector Dulce
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- Depuydt P.
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- Gazenkampf Andrey A.
- Gelée Bruno
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- Glietsch Rita
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- Gritsan Alexey I.
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- Guérin Claude
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- Humphreys Sally K.
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- Jarquin-Badiola Yves D.
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- Kansuke-Koyama
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- Knowles Serena
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- Kraßler Jens
- Krstevski Amanda
- Kulkarni Shreedhar
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- Kurahashi Kiyoyasu
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- Silesky Jimenez Juan I.
- Silesky Juan
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- Simonis Fabienne D.
- Sivashanmugavel Mageswaran
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- Soler Juan Alfonso
- Solis-Quesada Jaime E.
- Sotillo Diaz Juan Carlos J.
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- Srinivasa Latha
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- Staudinger Thomas
- Stephenson Lorraine
- Stewart Richard
- Stigler William
- Strauch Ulrich
- Sula Hektor
- Sun Renhua
- Surbatovic Maja
- Susana-Temprano
- Suzuki Hiroyuki
- Symmonds Sophie
- Szakmany Tamas
- Sánchez Rocío Manzano
- Sánchez-Ballesteros Jesús
- Søreide Eldar
- Tabhan Edgardo
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- Tainter Christopher
- Takaba Akihiro
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- Tanaka Hiroyuki
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- Terzi Nicolas
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- Vinzio Mauricio
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- Wang Chunting
- Wang Hua X.
- Wang Shou H.
- Wang Wei
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- Watt Philip
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- Wenham Tim
- Wessbergh Joanna
- Whitehead Christina
- Willett Emma L.
- Williams Alexandra J.
- Williams Karen E.
- Wise Matt P.
- Wittebole Xavier
- Wong Helen S.
- Woods Paul W.
- Wrathall David W.
- Wrigge Hermann
- Wu Ya Q.
- Xin-Hua Qiang
- Xu Yonghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L.
- Yeatts Dale J.
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste Luis J.
- Zacharas Giannis A.
- Zacharowski Kai D.
- Zani Gianluca
- Zantua Kim S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao H.
- Zhu Wei H.
- Zogheib Elie H.
- Ñamendys-Silva Silvio A.
- Ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe
Immunocompromised patients with acute respiratory distress syndrome : Secondary analysis of the LUNG SAFE database
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- Abad R.D.
- Abe Toshikazu
- Abroug Fekri
- Adams J.C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguirre Janet S
- Aguirre-Bermeo Hernan
- Aisa T.M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
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- Andruszkiewicz P.
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- Vascotto Ettore R.
- Vasquez Daniela N.
- Vega Luis D.
- Veljovic Milic
- Venti Aaron
- Vercueil Andre
- Vermassen Joris
- Verstraete Rik
- Villagomez A.
- Villagomez A.J.
- Villamagua Boris G.
- Villar Veronica
- Vinzio Mauricio
- Virgilio Corcoles G.
- Vitale Michela N.
- Volta Carlo A.
- Wang Chunting
- Wang Hua X.
- Wang Shou H.
- Wang Wei
- Warren J.
- Watanabe Eizo
- Watt Philip
- Welters I.D.
- Wenham T.
- Wessbergh Joanna
- Whitehead Christina
- Willett E.L.
- Williams A.J.
- Williams K.E.
- Wise M.P.
- Wittebole Xavier
- Wong Helen S.
- Woods Paul W.
- Wrathall D.W.
- Wrigge H.
- Wu Ya Q.
- Xin-Hua Qiang
- Xu Yinghao
- Yamaguchi Osamu
- Yamaji Yoshihiro
- Yao Qingchun
- Ye Zheng L.
- Yeatts D.J.
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste L.J.
- Zacharas Giannis A.
- Zacharowski Kai D.
- Zani Gianluca
- Zantua K.S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao H.
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao H.
- Zhu Wei H.
- Zogheib Elie
- Zumaran Aguilar Ronald
- Ñamendys-Silva S.A.
- ünal Necmettin
- Publication venue
- Publication date
- 01/01/2018
- Field of study
The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p < 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p < 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
Immunocompromised patients with acute respiratory distress syndrome: Secondary analysis of the LUNG SAFE database
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aisa Tharwat
- Aisiku Imo
- Ajetunmobi Olaitan
- Aker Mustafa
- Akyol Onat
- Al Dorzi Hasan M.
- Al Jabbary Ahmed
- Albaiceta Guillermo
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Alfonso Alec A. Tallet
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain
- Allan Russell
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier
- Altaf Wahid
- Alvarez António
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Mourad
- An Youzhong
- Andersen Finn
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo
- Antonelli Massimo
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Araujo Ana
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio
- Bailey Irene M.
- Bailey Mathew B.
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie
- Barberet Guillaume
- Baron Rebecca
- Baronia Arvind K.
- Barratt-Due Andreas
- Barros Filipa
- Barros Nelson C.
- Batra Hitesh
- Battle Ceri
- Bauer Philippe
- Beck Eduardo
- Beck Oliver
- Bedreag Ovidiu
- Beegle Scott H.
- Beitler Jeremy R.
- Bellani Giacomo
- Beloncle Francois
- Benslama Abdellatif
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans Frantz
- Besset Sebastien
- Bettini Lisandro R.
- Beuret Pascal
- Bezzi Marco G.
- Bhardwaj Vallish K.
- Bhowmick Kaushik
- Biehler Jerome
- Bigot Charlene
- Bihari Shailesh
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- Burtenshaw Andrew
- Burtin Philippe
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- Gordo Federico
- Gosselin Ryan
- Goubaux Bernard
- Grasselli Giacomo
- Graziani Romano
- Gregoretti Cesare
- Grelon Fabien
- Griffin Ruth
- Grigoriev Evgeny
- Grijalba Carolina Quintana
- Grissom Colin K.
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- Herbrecht Jean-Etienne
- Hermosa Cecilia
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- Heunks Leo
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- Hirata Akira
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- Honda Hiroyuki
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- Jovanovic Bojan
- Judy Claine
- Jurado Maria Teresa
- Kadaba Varsha
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- Kalaitzis Evangelos
- Kalkoff Michael
- Kamel Ghassan
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- Kamoun Salma
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- Khebbeb Samy
- Kheir Fayez
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- Larsson Niklas
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- Lemiale Virginie
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- Leon Yoshido Hector
- Li Bin
- Li Qingdong
- Li Qiong
- Li Wenwen
- Li Xiao L.
- Li Xinyu
- Li Yimin
- Li Yuan
- Li-Xin Zhou
- Liew Kong
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- Yamaji Yoshihiro
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- Zantua Kim
- Zazu Alan
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- Zender Hervé
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao
- Zhu Wei H.
- Zogheib Elie
- Ñamendys-Silva Silvio A.
- ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p < 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p < 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
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- Author
- ALARCÃO Isabel.
- Alexandre de Pádua Carrieri
- Ana Alice Vilas Boas
- BARDIN Laurence.
- BEIJAARD Douwe
- BENASSULY Jussara Sampaio.
- BOGDAN Robert.
- BRITO Antônia Edna
- CAIRES Susana.
- CALDERHEAD James.
- CALDERHEAD James.
- CALDERÓN Adolfo Ignacio
- CANDAU Vera Maria
- CLANDININ Jean
- COLE Ardra
- CONTRERAS José.
- CUNHA Maria Isabel
- CUNLIFFE Ann.
- DARLING-HAMMOND Linda.
- DELLAGNELO Eloise Helena Livramento
- DENZIN Norman.
- DUTRA Joel Souza
- EZER Hanna
- FERREIRA JÚNIOR Marcos Antônio
- FLEURY Afonso
- FREIRE Paulo.
- FREIRE Paulo.
- GHEDIN Evandro.
- GIOIA Denny
- GUION Lisa
- HARDY Cynthia
- HARPER Douglas
- HUERTAS Juan Antonio
- JENKINS Richard.
- KENNEDY Donald.
- KORTHAGEN Fred.
- KRAMER Sonia.
- KREMER-HAYON Lya
- LABERGE Yan.
- LAZZARIN Helen Cristina
- LE BOTERF Guy.
- LEAL Douglas Tavares Borges
- LIBÂNEO José Carlos.
- LONGAREZ Andréa Maturano
- LYON Reid
- MACHADO Hilka Vier
- MACKE Janaína.
- MALHOTRA Naresh.
- MALTA Maria Isabel Serra Guerreira
- MENGES Robert
- MINAYO M. C
- MISOCZKY Maria Ceci
- MOITA Filomena Maria Gonçalves Silva Cordeiro
- MORIN Edgar.
- Nathália de Fátima Joaquim
- NEUENFELDT Manuelli Cerolini
- NEUENFELDT Manuelli Cerolini
- OLIVEIRA Fátima Bayma.
- PAULA Ana Paula Paes
- POZO Juan Ignacio
- PRATT Michael.
- RIOS Terezinha Azerêdo
- ROZENDO Célia Alves
- RUAS Roberto.
- SAINSANLIEU Renaud.
- SCHÖN Donald.
- SCRUGGS Thomas
- SENGE Peter.
- SIQUEIRA Moema Miranda
- SLOMSKI Vilma Geni
- TARDIF Maurice
- TARDIF Maurice.
- THERRIEN Jacques
- TOLFO Suzana Rosa
- TRAGTENBERG Maurício.
- VERGARA Sylvia Constant
- VYGOTSKY Lev Semenovitch
- VYGOTSKY Lev Semenovitch
- ZARIFIAN Philippe.
- ZENTI Luciana
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study
- Author
- Aage Christiansen
- Aaron Venti
- Abdellatif Benslama
- Adam B Schlichting
- Adenilton M Rampinelli
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- Ahmad Yazid Bin Hj Abul Wahab
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- Rita Glietsch
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- Tamas Szakmany
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- Teresa Honrubia
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- Thierry Sottiaux
- Thomas Baltus
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- Thomas Kander
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- Tie H Qin
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- Valeria I Cerrato
- Valerie M Banner-Goodspeed
- Vallish K Bhardwaj
- Vallverdu P Imma
- Van Haren Frank
- Vanessa M Sales
- Vania A Brito
- Varsha Kadaba
- Vasilis Ourailogloy
- Venika Manoharan
- Venkatapura J Ramesh
- Veronica Villar
- Vesna Bumbasierevic
- Vesna Bumbasirevic
- Vijayanand Palaniswamy
- Vincenzo Pota
- Vincenzo Schiavone
- Virginie Lemiale
- Vivek Kakar
- Vladimir Cerny
- Wahid Altaf
- Wajdi Maazouzi
- Wei H Zhu
- Wei Wang
- Weihua Lu
- Wenkui Yu
- Wenwen Li
- William Stigler
- Wrigge Hermann
- Xavier Wittebole
- Xian Y Zhao
- Xiao B Huang
- Xiao L Li
- Xiaoming Luo
- Xing Y Zhang
- Xinyu Li
- Ya Q Wu
- Yaasen Arabi
- Yan Gao
- Yaseen M Arabi
- Yaseen M Arabi
- Yasuaki Ogino
- Yi Han
- Yimin Li
- Yonghao Xu
- Yoshihiro Yamaji
- Yoshinobu Kameyama
- Youssef Haddad
- Youzhong An
- Yozo Kashiwa
- Yu D Di
- Yuan N Gao
- Yuan Y Li
- Yuanhua Lu
- Yves D Jarquin-Badiola
- Zhe Zhai
- Zheng L Ye
- Zhenyang He
- Zhou Li-Xin
- Ángela Algaba
- Ángela González-Salamanca
- Publication venue
- 'European Respiratory Society (ERS)'
- Publication date
- 01/01/2021
- Field of study
Background: Current incidence and outcome of patients with acute hypoxaemic respiratory failure requiring mechanical ventilation in the intensive care unit (ICU) are unknown, especially for patients not meeting criteria for acute respiratory distress syndrome (ARDS).
Methods: An international, multicentre, prospective cohort study of patients presenting with hypoxaemia early in the course of mechanical ventilation, conducted during four consecutive weeks in the winter of 2014 in 459 ICUs from 50 countries (LUNG SAFE). Patients were enrolled with arterial oxygen tension/inspiratory oxygen fraction ratio ≤300 mmHg, new pulmonary infiltrates and need for mechanical ventilation with a positive end-expiratory pressure of ≥5 cmH2O. ICU prevalence, causes of hypoxaemia, hospital survival and factors associated with hospital mortality were measured. Patients with unilateral versus bilateral opacities were compared.
Findings: 12 906 critically ill patients received mechanical ventilation and 34.9% with hypoxaemia and new infiltrates were enrolled, separated into ARDS (69.0%), unilateral infiltrate (22.7%) and congestive heart failure (CHF; 8.2%). The global hospital mortality was 38.6%. CHF patients had a mortality comparable to ARDS (44.1% versus 40.4%). Patients with unilateral-infiltrate had lower unadjusted mortality, but similar adjusted mortality compared to those with ARDS. The number of quadrants on chest imaging was associated with an increased risk of death. There was no difference in mortality comparing patients with unilateral-infiltrate and ARDS with only two quadrants involved.
Interpretation: More than one-third of patients receiving mechanical ventilation have hypoxaemia and new infiltrates with a hospital mortality of 38.6%. Survival is dependent on the degree of pulmonary involvement whether or not ARDS criteria are reached
Characterisation of microbial attack on archaeological bone
- Author
- Abrantes Ana M
- Abreu Ana C
- Abreu Renato
- Abreu Renato
- Abreu Wilson
- Acedo Guadalupe
- Afonso Carlos
- Afreixo Vera
- Agudelo Mª E
- Alarcão Violeta
- Albuquerque Carlos
- Albuquerque Carlos
- Albuquerque Carlos
- Alencar Liana
- Alferes Valentim R
- Aliseda Isabel R
- Almada Lívia F
- Almeia António
- Almeida Ana
- Almeida Ana
- Almeida António
- Almeida António
- Almeida Armando
- Almeida Armando
- Almeida Fabrícia M
- Almeida Henrique
- Almeida Henrique A
- Almeida Henrique A
- Almeida Inês
- Almeida Jorge
- Almeida José P
- Almeida Maria
- Almeida Pedro
- Almeida Sidalina
- Alvarenga-Martins Nathália
- Alves B.
- Alves B.
- Alves Celeste
- Alves Dina
- Alves Gilberto
- Alves Helder
- Alves Josiane
- Alves José M
- Alves Juliana
- Alves Júlia M
- Alves Nuno
- Alves Nuno
- Alves Samuel
- Amado Diogo
- Amado João
- Amado Sandra
- Amaral Ana P
- Amaral Ana P
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Ambrósio Sara
- Amendoeira José
- Amorim Ana
- Amorim Ana P
- Amorim Helena
- Andrade Diogo
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade J. A
- Andrade Karizia V
- Andrade Renato
- Andrade Renato
- Andrade Susana
- Antunes Ana
- Antunes Ana
- Antunes Cristina
- Antunes Lígia
- Antunes Sandra
- Antunes Sandra
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- Aparício Graça
- Aparício José
- Apolinário-Hagen Jennifer
- Apolinário-Hagen Jennifer
- Aquino Caroline Q
- Aquino Caroline Q
- Aquino Priscila S
- Aquino Priscila S
- Araujo André R
- Araújo Beatriz
- Araújo Elsa
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- Araújo Patrícia
- Araújo Patrícia
- Armas-Gonzalez Yadira
- Arreguy-Sena Cristina
- Arreguy-Sena Cristina
- Ascenso Rita T
- Ascenso Rita T
- Assunção Victor
- Augusto Cláudia
- Avelelas Francisco
- Ayoub Rodrigo
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azevedo Julieta
- Azevedo Julieta
- Azevedo Marcelo
- Azevedo Maria H
- Azevedo Mª H
- Azevedo Tatiana
- Azzalis L.
- Baffour Gabriel
- Baffour Gabriel
- Bairros Keila
- Baixinho Cristina L
- Bajo Roberto
- Baltazar Ana L
- Barbeiro Ana P
- Barbosa Flávio
- Barbosa Tiago
- Barreira Eduarda
- Barreiros Luísa
- Barros Luísa
- Barros Luísa
- Barros Teresa
- Barroso Isabel
- Barroso Isabel
- Barroso Isabel
- Barroso João
- Basto Marta L
- Basto Marta L
- Basto Marta L
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- Bastos Fernanda
- Batalha Joana
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- Batista Marco
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- Baylina Pilar
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- Benevides Joana
- Bento Elisabete
- Bento Elisabete
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- Blanco Valeriana G
- Boavida José
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- Bordin Ronaldo
- Bordin Ronaldo
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- Botelho Mª F
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- Caballero Francisco P
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- Carvalho Rui
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- Da Motta Carolina
- Da Motta Carolina
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- Dias Sara S
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- Dinis Alexandra
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- Dixe Anjos
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- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Domingos Joana
- Domingos Samuel
- Domingues Cátia
- Domingues Gabriela
- Domingues J. N
- Dreyer Laysa C
- Duarte Catarina
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- Duarte Diana
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- Duarte Soraia
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- Escoval Ana
- Espada Mário
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- Estrela Jéssica
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- Faria Luís
- Faria Melissa
- Faria Paula
- Faria Paula
- Faustino António
- Faustino António
- Faustino António
- Fernandes Adília
- Fernandes Ana R
- Fernandes Andreia
- Fernandes Beatriz
- Fernandes Helder M
- Fernandes Jorge C
- Fernandes Morgana C
- Fernandes Patrícia
- Fernandes Patrícia
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- Fernandez Mª J L
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- Ferraz Vera
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- Ferreira Ana
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- Ferreira Paulo P
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- Figueiredo João P
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- Figueiredo Mª H
- Figueiredo Paulo
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- Filho João G
- Filho João G
- Filho João G
- Filipe Vítor
- Fiorin Bruno H
- Fleig Tânia C
- Fleig Tânia C
- Fonseca Ana R
- Fonseca F.
- Fonseca F.
- Fonseca Virgínia
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- Fontes-Ribeiro Carlos
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- Fotschl Ulrike
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- Furtado G.
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- Garcia-Gordillo Miguel A
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- Hernandez-Martinez Francisco J
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- Melo Rosa
- Melo Rosa
- Mendes Aida
- Mendes Ana
- Mendes Ana
- Mendes Ana
- Mendes Ana L
- Mendes Ana L
- Mendes Ana L
- Mendes Elenice
- Mendes F
- Mendes F.
- Mendes Felismina
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Francisco
- Mendes Francisco
- Mendes Francisco
- Mendes Isabel
- Mendes Isabel
- Mendes Joana
- Mendes Maria F
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Romeu
- Mendes Romeu
- Mendes Romeu
- Mendes Zaida
- Mendonça Carlos
- Mendonça Nuno
- Mendonça Paula
- Mendonça Paula
- Mendonça Verónica
- Mendonça Verónica
- Meneghetti Vanize
- Meneses Rui
- Menezes Ruth L
- Menino Eva
- Menino Eva
- Menino Eva
- Menino Eva
- Mercê Cristiana
- Mesquita Helena
- Mesquita Helena
- Mesquita João R
- Midões Cristiana
- Milanés Gemma M
- Minas Bárbara
- Minghelli Beatriz
- Minghelli Beatriz
- Miranda Cristiana
- Miranda Marta
- Miranda Natacha F
- Monago Fatima M
- Monago Fatima M
- Monago Fátima M
- Monago Rocio M
- Monteiro Diogo
- Monteiro Helena
- Monteiro Joana
- Monteiro Lina
- Monteiro Luís
- Monteiro M. J
- Monteiro M. J
- Monteiro Mª J
- Monteiro Sílvia
- Morais Carminda
- Morais Marina A
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Nuno
- Moreira Eliana
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Isabel
- Moreira Liliana
- Moreira Liliana
- Moreira Rita L
- Moreno Ana L
- Morgado Alice
- Morgado Sónia
- Morgado Sónia
- Morna Clementina
- Morna Clementina
- Morouço Pedro
- Morouço Pedro
- Mota Maria
- Mota Maria
- Mota Priscilla
- Moura Cynthia B
- Moura-Ramos Mariana
- Mouroço Pedro
- Mourão Ricardo
- Mártires Alice
- Mónico Lisete
- Mónico Lisete
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Nascimento Daniela
- Nascimento Maria S
- Nascimento V. B
- Natal Sônia
- Nave Filipe
- Nave Filipe
- Nazario Nazare
- Nazario Nazare
- Nazario Nazare
- Nazaré Cristina
- Nazário Nazaré O
- Neco Sofia
- Nelas Paula
- Neto João S
- Neves Carmo
- Neves Joana
- Neves Joel
- Neves Jéssica
- Neves Jéssica
- Neves Miguel
- Neves Sofia
- Neves Vanessa
- Nicola Paulo
- Nogueira Conceição
- Nogueira Paulo
- Nogueira Paulo
- Noné Ana
- Novais Sandra
- Novais Sandra
- Novais Sónia
- Novais Sónia
- Novo André
- Nugem Rita C
- Nugem Rita C
- Nunes Amélia
- Nunes Amélia F
- Nunes Carla
- Nunes Carla
- Nunes Carla
- Nunes Hélder
- Nunes Liliana
- Nunes S.
- Nuñez Cristina G
- Oliva Jefferson T
- Olivares Pedro R
- Oliveira Adriana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana P
- Oliveira Anabela
- Oliveira Bibiana F
- Oliveira Bárbara
- Oliveira Camila A
- Oliveira Catarina
- Oliveira Denize C
- Oliveira Edmar S
- Oliveira Elizabete A
- Oliveira Emanuel
- Oliveira Eunice G
- Oliveira Eunice G
- Oliveira Isabel
- Oliveira Lara L
- Oliveira Manuel
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Mirna F
- Oliveira Raul
- Oliveira Rita
- Oliveira Rita
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Sara
- Oliveira Sebastião T
- Oliveira Sebastião T
- Oliveira Suzete
- Oliveira Teresa C
- Oliveira Teresa T
- Oliveira Vânia P
- Olszewer Efrain O
- Ortiga Angela B
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Pacheco José
- Padez Cristina
- Padilha José M
- Padilha José M
- Padilha José M
- Padilha José M
- Paixão S.
- Paixão Susana
- Paixão Susana
- Palmeira Lara
- Palmeira Lara
- Paraíso Nilson
- Paredes Hugo
- Parente Alexandra
- Parraça José A
- Parraça José A
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro D
- Parreira Pedro M
- Parreira Pedro M
- Parreira Pedro M
- Passadouro Rui
- Passadouro Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paúl Constança
- Paúl Constança
- Paúl Constança
- Pedreiro Ana
- Pedro Ana R
- Pedro Ana R
- Pedro Luísa
- Pedrosa Dora
- Pedroso Rosa
- Peixoto Ermelindo
- Peixoto-Plácido Catarina
- Peralta Teresa
- Pereira A.
- Pereira Alexandre
- Pereira Alexandre
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana M
- Pereira Ana M
- Pereira Ana M
- Pereira Ana T
- Pereira Ana T
- Pereira Anabela
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Cristina
- Pereira Elayne
- Pereira Elsa S
- Pereira Filipe
- Pereira Filomena
- Pereira Filomena
- Pereira Juliana
- Pereira Marta
- Pereira Olívia R
- Pereira Rafael
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Pimenta Luís
- Pimenta Rui
- Pimentel Francisco
- Pimentel João
- Pimentel Rafaela
- Pinheiro Ana B
- Pinheiro Ana B
- Pinheiro Arminda A
- Pinheiro Patrícia C
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Tânia
- Pinto Carlos
- Pinto Francisca
- Pinto Isabel C
- Pinto Isabel C
- Pinto J. L
- Pinto Joana
- Pinto M R
- Pinto Mª R
- Pinto Paulo F
- Pinto Sara
- Pinto Ítalo N
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pires Filipa
- Pires Filipa
- Pires Tânia
- Pires Tânia
- Pisco Jacinta
- Pivetta Hedioneia F
- Piñero Ana S
- Poeta Susana
- Porta-Nova Rui
- Postolache Gabriela
- Postolache Octavian
- Poço Mariana
- Prado Alessandro
- Prata Ana R
- Prebianchi Helena
- Presado Mª H
- Preto Vera
- Príncipe Fernanda
- Pulido-Fuentes Montserrat
- Pérez-Caballero Francisco L
- Pérez-Caballero Francisco L
- Queirós Paulo
- Quelhas Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Quintana-Montesdeoca Mª P
- Quirino Diogo
- Rabiais Isabel
- Rafael Helga
- Rainho Conceição
- Rainho Conceição
- Rainho Conceição
- Rama Luís
- Rama Luís
- Rama Luís
- Ramalhete Cátia
- Ramalho André
- Ramalho André
- Ramalho Fátima
- Ramalho Sónia
- Ramalho Sónia
- Ramalho Sónia A
- Ramirez Francisco B
- Ramirez Francisco B
- Ramos Maurício R
- Raposo Vítor R
- Rei Ana C
- Reina Mercedes G
- Reis Alcinda C
- Reis Ana S
- Reis Arsénio
- Reis Cláudia
- Reis Laura
- Reis Victor M
- Reses Manoela
- Reuter Éboni M
- Ribas Patrícia
- Ribeiro Andrea
- Ribeiro Andrea
- Ribeiro Diana
- Ribeiro Fernando
- Ribeiro Jaime
- Ribeiro Jaime
- Ribeiro José C
- Ribeiro João
- Ribeiro Lígia C
- Ribeiro Maria
- Ribeiro Maria
- Ribeiro Maximiano
- Ribeiro Olivério
- Ribeiro Olivério
- Ribeiro Samila G
- Ribeiro Sandra
- Ribeiro Sandra
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro-Varandas Edna
- Richaud Sylvina
- Rocha C.
- Rocha Clara
- Rocha Clara
- Rocha Clara
- Rocha Mª C
- Rocha Mª C
- Rocha Saulo V
- Rocha Saulo V
- Rodrigo António
- Rodrigues Alexandre
- Rodrigues Alexandre
- Rodrigues Alexandrina
- Rodrigues António
- Rodrigues Cátia
- Rodrigues Diana
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rosa
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Teresa
- Rodrigues Vítor
- Rodrigues Vítor
- Rodriguez Cláudia K
- Rodriguez-De-Vera Bienvendida C
- Rodriguez-De-Vera Bienvenida
- Rodriguez-De-Vera Bienvenida C
- Rodríguez Ana B
- Rodríguez-De-Vera Bienvenida-Del-Carmen
- Rombo João
- Roque Fátima
- Rosa Manuel S
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Roger S
- Rosa Roger S
- Rosado António
- Rosado António
- Rosário Rafaela
- Ruben Rui B
- Ruivo Joana
- Saavedra Francisco
- Saboga-Nunes Luís
- Saboga-Nunes Luís
- Sala José A
- Sala José A
- Sales Tiago
- Salgueiro Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salvador Mª C
- San-Martin Elisabete A
- Santana Miguel
- Santana Paula
- Santiago Conceição
- Santiago Eujcely C
- Santiago Eujcely C
- Santiago Luiz
- Santo Inês
- Santo Inês
- Santos Adriana
- Santos Ana
- Santos Bruno
- Santos Bruno
- Santos Erica
- Santos Flávia
- Santos Joana
- Santos Joana
- Santos Jorge
- Santos João
- Santos Leonino S
- Santos Luísa
- Santos Marina S
- Santos Marlene
- Santos Marlene
- Santos Nuno
- Santos Osvaldo
- Santos Osvaldo
- Santos Osvaldo
- Santos Rafael B
- Santos Rafael B
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos-Rocha Rita
- Sardo Dolores
- Sardo Pedro
- Sardo Pedro
- Sarmento-Ribeiro Ana B
- Sarreira-Santos Alexandra
- Sarroeira Cassilda
- Schneider Dulcineia
- Schneider Dulcineia
- Schneiders Paloma B
- Schroeder Silvana S
- Schukg Susann
- Seabra André
- Seabra Daniel
- Seabra Daniel
- Seabra Paulo
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seiça Luís
- Seppänen Ulla-Maija
- Serapioni Mauro
- Serra Ana
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Severino Sandy
- Siba Wafa A
- Silva Ana M
- Silva Ana M
- Silva Andrea G
- Silva André
- Silva Antónia
- Silva Armando
- Silva Carina
- Silva Carla R
- Silva Carlos
- Silva Carlos F
- Silva Catarina
- Silva Cláudia
- Silva Cláudia D
- Silva Daniel
- Silva Daniel
- Silva Darlen
- Silva David
- Silva Eduardo
- Silva Elsa
- Silva Ernestina
- Silva Helena R
- Silva Helena R
- Silva Iryna
- Silva Isabel
- Silva Joana
- Silva Joana
- Silva Joana
- Silva Luís D
- Silva Luís D
- Silva Maiza M
- Silva Manuel C
- Silva Margarida
- Silva Margarida
- Silva Maria A
- Silva Marilene
- Silva Marilene
- Silva Norberto
- Silva Paula
- Silva Paula A
- Silva Pedro
- Silva Pedro
- Silva Rafael
- Silva Rita
- Silva Rita
- Silva Rita P
- Silva Sara
- Silva Sara
- Silva Sara
- Silva Susana
- Silva Tatiane M
- Silva Vânia
- Silveira Paulo
- Sim-Sim Margarida
- Simões Alexandra
- Simões Cristina
- Simões João
- Simões Paulo C
- Simões Sónia
- Simões Ângela
- Siqueira Mariana S
- Siqueira Mariana S
- Soar Cláudia
- Soares Célia
- Soares Fátima
- Soares Fátima
- Soares Raquel
- Soares Salete
- Soares Sérgio
- Soares Valter
- Sousa Ana P
- Sousa Ana S
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Carla
- Sousa Caroline R
- Sousa Cesar
- Sousa D.
- Sousa Diana
- Sousa Gilberta
- Sousa Gilberta
- Sousa Gracinda
- Sousa Jani
- Sousa Joana
- Sousa Joana
- Sousa Luís
- Sousa Marina
- Sousa Marina
- Sousa Nelson
- Sousa Nelson
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Souza Clóvis A
- Souza Géssica M
- Souza Juliana A
- Souza Nelba R
- Souza Nelba R
- Spolaôr Newton
- Svensson Lola
- Sá Dayse
- Tapadas Rodrigo
- Tavares Aida I
- Tavares Ana
- Tavares Ana S
- Tavares José
- Tavares Mariline
- Tavares Nuno
- Teixeira A.
- Teixeira Ana
- Teixeira Ana
- Teixeira Ana M
- Teixeira Laetitia
- Teixo Ricardo
- Teles Patrícia
- Tena José M
- Tena Maria J
- Tenedório José A
- Tim-Tim Carolina
- Tomaz Jorge
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina C
- Tomás Teresa
- Topa Joana
- Torgal Jorge
- Torgal Jorge
- Torres Ana
- Torres Rui
- Trigo Africa P
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Tuna Ana R
- Tytgat Ite
- Uba-Chupel M.
- Uba-Chupel Mateus
- Ugalde Lierni U
- Ugartemendia Lierni
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Vale-Dias Luz
- Vale-Dias Maria L
- Valente Ana R
- Valente Carolina
- Valente Jorge
- Valente João
- Valim Frederico C
- Valim Frederico C
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Varandas Edna
- Vardasca Ricardo
- Vardasca Ricardo
- Vasconcelos Carlos
- Vasconcelos Carlos
- Vasconcelos Lélia R
- Vasconcelos Rita
- Vasconcelos Rita
- Vaz Daniela C
- Vaz Josiana A
- Vehreschild Viktor
- Vehreschild Viktor
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga-Branco Mª
- Velosa Fábia
- Veloso Milene
- Ventura David
- Ventura Maria
- Ventura Rita
- Ventura Sandra
- Vicente Corália
- Vicente Corália
- Vicente Corália
- Vicente Sara
- Vicente Sónia
- Vidal Eglidia F
- Viega-Branco Maria
- Vieira André
- Vieira Margarida
- Vieira Viviane L
- Vieitez Juan G
- Villanueva Ana G
- Vincha Kellem R
- Vinha Ana F
- Virgolino Ana
- Vizzotto Betina P
- Vélez Marta M
- Welter Aline
- Xavier Ana
- Xavier Ana
- Xavier Sandra
- Xavier Sandra
- Zilhão Adriano
- Publication venue
- Publication date
- 01/01/2004
- Field of study
As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved
Death in hospital following ICU discharge: insights from the LUNG SAFE study
- Author
- Aage Christiansen
- Aaron Venti
- Abdellatif Benslama
- Adam B Schlichting
- Adenilton M Rampinelli
- Aditya Uppalapati
- Adrian Donnelly
- Adriana M Fernandez
- Adrien Robine
- Ahmed S Al Jabbary
- Ai Y Hang
- Aiman Tulaimat
- Akihiro Takaba
- Akinori Uchiyama
- Akira Hirata
- Alain Combes
- Alain M Dive
- Alain Mercat
- Alain U Alisasis
- Alan Zazu
- Alberto Deicas
- Alec A Tallet Alfonso
- Alejandro A Saez
- Alejandro G Castro
- Alejandro R Bruhn
- Alek Kumar
- Alessandro Protti
- Alessia Mattei
- Alex Mcleod
- Alex Morton
- Alexandra Ceniceros-Barros
- Alexandra J Williams
- Alexandra Marcu
- Alexandre Demoule
- Alexandre Molin
- Alexey I Gritsan
- Alfons Arizmendi
- Aline Ascoli
- Alistair Nichol
- Alma Cani
- Alvaro Ramirez-Gutierrez
- Amanda Krstevski
- Amine Ali Zeggwagh
- Amine Ali Zeggwagh
- Ana Carolina P Antônio
- Ana M Araujo
- Ana M Pellicer
- Anais Briquet
- Anatole Harrois
- Anders Aneman
- Anders Larsson
- Andre Vercueil
- Andrea Coppadoro
- Andrea Cortegiani
- Andrea Lombardo
- Andrea N Cracchiolo
- Andrea Tinnirello
- Andreas Barratt-Due
- Andreas W Reske
- Andres Esteban
- Andrew Ferguson
- Andrew J Burtenshaw
- Andrey A Gazenkampf
- Angela Delsing
- Aniko D Frigyik
- Anil P Hormis
- Anitha Shenoy
- Anna Hunt
- Anna Oscarsson Tibblin
- Anna Rossi
- Anna T Dowling
- Anna-Karin Morin
- Anne Adolfsson
- Anne B Guttormsen
- Antero do Vale Fernandes
- Antoine Pronovost
- Antonino Giarratano
- Antonio Artigas
- Antonio Braschi
- Antonio G Jimenez
- Antonio L Ruiz-Aguilar
- Antonio Pesenti
- Antonio Pesenti
- António M Alvarez
- António M Messias
- Aogan C O'Muircheartaigh
- Areej Javeed
- Ariel Chena
- Arnaud Follin
- Arthur S Slutsky
- Arvind K Baronia
- Ashley Schomer
- Ashok S Raj
- Asisclo J Villagomez
- Asisclo Villagomez
- Asma Ben Souissi
- Aurelia M Martinho
- Aylin Seven
- B Taylor Thompson
- Bao H Zhu
- Barbara Brunettini
- Barrett T Kitch
- Barry Kennedy
- Basak Ceyda Meco
- Beatriz C Tan
- Bellani Giacomo
- Bernard Goubaux
- Bernhard Holzgraefe
- Bhagyesh Shah
- Bin Li
- Bingyu Qin
- Bojan Jovanovic
- Boonsong Patjanasoontorn
- Boris G Villamagua
- BPg Hj Ismail
- Brigit L Roberts
- Brit Å Sjøbø
- Bruno Gelée
- Bruno S Oliveira
- Candelaria De Haro
- Carlo A Volta
- Carlos A Pellegrini
- Carlos S Pereira
- Carolina Quintana Grijalba
- Carolina S Insaurralde
- Carolina Serra
- Caroline Berghe
- Caroline C MacFie
- Catalina Forteza
- Cecilia Carbayo-Gorriz
- Cecilia Hermosa
- Ceri E Battle
- Cesar A Cortez
- Cesar Cesar Azevedo
- Cesar P Perez
- Charlene Le Moal
- Charles Gomersall
- Christian C Rylander
- Christian Dellera
- Christian M Ramirez-Alfaro
- Christina Whitehead
- Christopher J Scott
- Christopher Nutt
- Christopher Tainter
- Chunting Wang
- Claine Judy
- Claire Reynolds
- Clare Mellis
- Claude Guérin
- Claudia A Ortiz
- Claudia R Estrella
- Claudio H Gonçalves
- Claudio Piras
- Colette Seasman
- Colin K Grissom
- Colin Mcarthur
- Colin S Black
- Corcoles G Virgilio
- Corinne Leemann-Refondini
- Cristina M Coxo
- Cristina Santos
- Cédric Daubin
- Daisuke Niimi
- Dale J Yeatts
- Damien Roux
- Dan E Corneci
- Dan Hadfield
- Dana R Tomescu
- Daniel F McAuley
- Daniel O Beraldo
- Daniel R Crouch
- Daniel R Crouch
- Daniel R Gonzalez
- Daniel V Collins
- Daniela Albiero
- Daniela M Palma
- Daniela N Vasquez
- Daniele M Combaux
- Danielle A Fawkes
- Danielle C Fontenele
- Danielle J Hacking
- Danielle Nobrega
- Danielle Reuter
- Danny McAuley
- Dany Goldgran-Toledano
- David D Llinares Moya
- David W Wrathall
- Deborah M Inskip
- Deeban Ganesan
- Denis Doyen
- Diego Pastor Marcos
- Dimitrios Matamis
- Dina Gomaa
- Dina Gomaa
- Dina Ismail
- Dk Maizatul Aiman
- Donald A Irvine
- Donall O'Croinin
- Dorel Sandesc
- Dorothy M Breen
- Dorothée Carpentier
- Dulce Dector
- Dulce M Dector
- Dácil Parrilla Toribio
- Ed Bajwa
- Eddy Fan
- Edel A Meaney
- Edgardo E Tabhan
- Edgardo Nuñez
- Edgardo Tabhan
- Eduardo Beck
- Eduardo F Labarca
- Eimhin S Dunne
- Eizo Watanabe
- Eldar Søreide
- Electra E Stamou
- Elena Frati
- Elena Gallego Curto
- Elena Perez Losada
- Eleni K Mouloudi
- Eleni V Massa
- Elie H Zogheib
- Elisa Estenssoro
- Elisabetta Pecci
- Elise P Sauvadet
- Ellada V Kiourtzieva
- Emilio M Osman
- Emma L Willett
- Emre Erbabacan
- Enrique A Piacentini
- Enrique Cereijo
- Erika E Borotto
- Erin Nishikawa
- Esther Bermejo Lopez
- Esther Diaz-Rodriguez
- Ettore R Vascotto
- Eva O Nagy
- Evangelos Kalaitzis
- Evgeny Grigoriev
- Ewan C Goligher
- Fa C Zhou
- Fabiana Madotto
- Fabien Grelon
- Fabienne D Simonis
- Fabio Tarantino
- Fabrice Daviaud
- Fahd Amir
- Fan Zhang
- Fanny Klasen
- Farshad Heidari
- Fayez Kheir
- Fayez M Kheir
- Federico Gordo
- Fekri Abroug
- Felipe A Aliaga
- Felipe T Martinez
- Ferdinando Raimondi
- Fernando G George
- Fernando Rios
- Ferran Roche-Campo
- Filipa M Barros
- Finn H Andersen
- Flavia A Loiacono
- Francesca Rabboni
- Francesco L Santoli
- Francesco Mojoli
- Francesco Raponi
- Francis Schneider
- Francisca G Cazorla-Barranquero
- Francisco Esteve
- Francisco Javier Flores Mejia
- Francisco P Huerta
- Francois Beloncle
- Frank van Haren
- Frank van Haren
- Frantz Berkelmans
- Fredrik Schiöler
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- Suresh Shindhe
- Susan M Marum
- Susana Temprano
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- Sánchez I Rafael
- Sébastien Jochmans
- T John Trinder
- T Sottiaux
- Tadaaki Takada
- Takeshi Ueda
- Tamas Szakmany
- Tao Yu
- Tarek Dendane
- Teresa Honrubia
- Tharwat M Aisa
- Theonymfi G Papavasilopoulou
- Thomas Baltus
- Thomas C Blakeman
- Thomas Collyer
- Thomas Kander
- Thomas Staudinger
- Tie H Qin
- Tim Wenham
- Tomas P Roser
- Tomaz Mesar
- Tomaz Mesar
- Tommaso Fossali
- Tomoaki Hashida
- Tomofumi Harasawa
- Tomoyuki Nakamura
- Toni E Mckenna
- Toshikazu Abe
- Trevor W Oetting
- Troy S Browne
- Tài Pham
- Tài Pham
- Ulrich Strauch
- Ushio Higashijima
- Valeria I Cerrato
- Valerie M Banner-Goodspeed
- Vallish K Bhardwaj
- Vallverdu P Imma
- Vanessa M Sales
- Vania A Brito
- Varsha Kadaba
- Vasilis Ourailogloy
- Venika Manoharan
- Venkatapura J Ramesh
- Veronica Villar
- Vesna Bumbasierevic
- Vesna Bumbasirevic
- Vijayanand Palaniswamy
- Vincenzo Pota
- Vincenzo Schiavone
- Virginie Lemiale
- Vivek Kakar
- Vladimir Cerny
- Wahid Altaf
- Wajdi Maazouzi
- Waqar Kashif
- Wei H Zhu
- Wei Wang
- Weihua Lu
- Wenkui Yu
- Wenwen Li
- William Stigler
- Xavier Wittebole
- Xian Y Zhao
- Xiao B Huang
- Xiao L Li
- Xiaoming Luo
- Xing Y Zhang
- Xinyu Li
- Ya Q Wu
- Yaasen Arabi
- Yan Gao
- Yaseen M Arabi
- Yasuaki Ogino
- Yi Han
- Yimin Li
- Yonghao Xu
- Yoshihiro Yamaji
- Yoshinobu Kameyama
- Younsuck Koh
- Youssef Haddad
- Youzhong An
- Yozo Kashiwa
- Yu D Di
- Yuan N Gao
- Yuan Y Li
- Yuanhua Lu
- Yves D Jarquin-Badiola
- Zhe Zhai
- Zheng L Ye
- Zhenyang He
- Zhou Li-Xin
- Ángela Algaba
- Ángela González-Salamanca
- Ñ P Nassar Jr
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
ackground: To determine the frequency of, and factors associated with, death in hospital following ICU discharge to the ward.
Methods: The Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE study was an international, multicenter, prospective cohort study of patients with severe respiratory failure, conducted across 459 ICUs from 50 countries globally. This study aimed to understand the frequency and factors associated with death in hospital in patients who survived their ICU stay. We examined outcomes in the subpopulation discharged with no limitations of life sustaining treatments ('treatment limitations'), and the subpopulations with treatment limitations.
Results: 2186 (94%) patients with no treatment limitations discharged from ICU survived, while 142 (6%) died in hospital. 118 (61%) of patients with treatment limitations survived while 77 (39%) patients died in hospital. Patients without treatment limitations that died in hospital after ICU discharge were older, more likely to have COPD, immunocompromise or chronic renal failure, less likely to have trauma as a risk factor for ARDS. Patients that died post ICU discharge were less likely to receive neuromuscular blockade, or to receive any adjunctive measure, and had a higher pre- ICU discharge non-pulmonary SOFA score. A similar pattern was seen in patients with treatment limitations that died in hospital following ICU discharge.
Conclusions: A significant proportion of patients die in hospital following discharge from ICU, with higher mortality in patients with limitations of life-sustaining treatments in place. Non-survivors had higher systemic illness severity scores at ICU discharge than survivors