INTERVENÇÃO PSICOLÓGICA NO CONTEXTO ESCOLAR: DIÁLOGOS NECESSÁRIOS

Esta pesquisa objetiva relatar uma experiência sobre intervenções psicológicas realizadas no contexto escolar. Trata-se de um relato de experiência sobre as intervenções psicológicas necessárias em um cenário escolar envolvendo estudantes do sétimo ano de uma escola do extremo oeste de Santa Catarina, elaborado no componente curricular de Estágio Básico III do curso de Psicologia da Universidade do Oeste de Santa Catarina (UNOESC). Durante os encontros, por meio de dinâmicas que oportunizassem a verbalização dos estudantes, estes trouxeram de maneira singular desconfortos emocionais e características ansiógenas que atravessam seu cotidiano escolar. Assim, o estudo reconhece a importância de diálogos sobre família, bullying abuso sexual e amizades, a fim de auxiliar os estudantes a reelaborarem suas vivências

Levamisole, a cocaine cutting agent, induces acute and subchronic systemic alterations in Wistar rats

The use of the anthelmintic levamisole as a cocaine adulterant has been increasing worldwide. Complications caused by this association include systemic vasculitis, agranulocytosis, neutropenia, tissue necrosis, pulmonary hemorrhage, and renal injury. Data about toxicity of levamisole are scarce, therefore the aim of this study was to evaluate the acute and subchronic toxic effects of levamisole in rats. Male Wistar rats received saline or levamisole by intraperitoneal route at the doses of 12, 24 and 36 mg/kg in the acute toxicity test; and at 3, 6 and 12 mg/kg in the subchronic toxicity test. Toxicity was evaluated using behavioral, cognitive, renal, hematological, biochemical and histopathological parameters. Acute administration of levamisole caused behavioral and histopathological alterations. Subchronic administration caused behavioral, cognitive and hematological alterations (p < 0.0001 and p < 0.05, respectively), impairment of liver and kidney functions (p < 0.05), and changes of antioxidant defenses (p ≤ 0.0001). Both administrations produced toxic effects of clinical relevance, which make levamisole a dangerous cutting agent. Furthermore, the knowledge of these effects can contribute to the correct diagnosis and treatment of cocaine dependents with unusual systemic alterations