Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism

Trombidid mites have a unique lifecycle in which only the larval stage is ectoparasitic. In the superfamily Trombiculoidea (“chiggers”), the larvae feed preferentially on vertebrates, including humans. Species in the genus Leptotrombidium are vectors of a potentially fatal bacterial infection, scrub typhus, which affects 1 million people annually. Moreover, chiggers can cause pruritic dermatitis (trombiculiasis) in humans and domesticated animals. In the Trombidioidea (velvet mites), the larvae feed on other arthropods and are potential biological control agents for agricultural pests. Here, we present the first trombidid mites genomes, obtained both for a chigger, Leptotrombidium deliense, and for a velvet mite, Dinothrombium tinctorium

Additional file 1: of Quantitative assessment of radiation dose and fractionation effects on normal tissue by utilizing a novel lung fibrosis index model

Table S1. A list of experimentally derived mouse lung α/β ratios from the literatures with special reference to late lung damage. Data is presented as Mean ± SE. (B.R. = breathing rate, F = female, BPM = breath per minute, M = male, d = day, wk. = week). Figure S1. Reciprocal total isoeffect dose for ED 50 as a function of dose per fraction. The data points were simulated using eq. (3). The α/β was obtained as the ratio of the intercept and the slope of the line using the conventional Fe plot. Appendix. CT histogram profiling in differential diagnosis of emphysema or pleural effusions. (DOCX 350 kb