Ageism and Perceptions of Vulnerability: Framing of Age during the Covid-19 Pandemic

Media representations of the Covid-19 pandemic and its devastating consequences have shaped people’s fears, anxiety, and perceptions of vulnerability. Social scientists have examined the consequences of how information is “framed.” Framing theory asserts that issues can be portrayed differently by emphasizing or de-emphasizing aspects and information. According to Lakoff (2004) the impact of a message is not based on what is said but how it is said. Theories of framing focus on how the media frames issues, which then structure and shape attitudes and policies. A news article serves as a frame for an intended message. This paper examines the ways that “age” has been framed during the Covid-19 pandemic. One of the most dominant frames in terms of COVID-19 coverage is how the pandemic has been analyzed through the lens of age and framed in terms of age discrimination. The results of news articles appearing in several prominent newspapers indicate that the perceptions of elders and their vulnerabilities to severe consequences from Covid-19 are likely to help perpetuate or create age discrimination

Ageism and Perceptions of Vulnerability: Framing of Age during Covid-19 Pandemic

Media representations of the Covid-19 pandemic and its devastating consequences have shaped people’s fears, anxiety, and perceptions of vulnerability. Social scientists have examined the consequences of how information is “framed.” Framing theory asserts that issues can be portrayed differently by emphasizing or de-emphasizing aspects and information. According to Lakoff (2004) the impact of a message is not based on what is said but how it is said. Theories of framing focus on how the media frames issues, which then structure and shape attitudes and policies. A news article serves as a frame for an intended message. This paper examines the ways that “age” has been framed during the Covid-19 pandemic. One of the most dominant frames in terms of COVID-19 coverage is how the pandemic has been analyzed through the lens of age and framed in terms of age discrimination. The results of news articles appearing in several prominent newspapers indicate that the perceptions of elders and their vulnerabilities to severe consequences from Covid-19 are likely to help perpetuate or create age discrimination

HOVERCAT: a novel aerial system for evaluation of aerosol-cloud interactions

Aerosols have a profound impact on cloud microphysics through their ability to serve as ice nucleating particles (INPs). As a result, cloud radiative properties and precipitation processes can be modulated by such aerosol&ndash;cloud interactions. However, one of the largest uncertainties associated with atmospheric processes is the indirect effect of aerosols on clouds. The need for more advanced observations of INPs in the atmospheric vertical profile is apparent, yet most ice nucleation measurements are conducted on the ground or during infrequent and intensive airborne field campaigns. Here, we describe a novel measurement platform that is less expensive and smaller (&lt;&thinsp;5&thinsp;kg) when compared to traditional aircraft and tethered balloon platforms and that can be used for evaluating two modes of ice nucleation (i.e., immersion and deposition). HOVERCAT (Honing On VERtical Cloud and Aerosol properTies) flew during a pilot study in Colorado, USA, up to 2.6&thinsp;km above mean sea level (1.1&thinsp;km above ground level) and consists of an aerosol module that includes an optical particle counter for size distributions (0.38&ndash;17&thinsp; &micro;m in diameter) and a new sampler that collects up to 10 filter samples for offline ice nucleation and aerosol analyses on a launched balloon platform. During the May 2017 test flight, total particle concentrations were highest closest to the ground (up to 50&thinsp;cm&minus;3 at &lt;&thinsp;50&thinsp;m above ground level) and up to 2 in 10 2 particles were ice nucleation active in the immersion mode (at &minus;23&thinsp;∘C). The warmest temperature immersion and deposition mode INPs (observed up to &minus;6 and &minus;40.4&thinsp;∘C, respectively) were observed closest to the ground, but overall INP concentrations did not exhibit an inverse correlation with increasing altitude. HOVERCAT is a prototype that can be further modified for other airborne platforms, including tethered balloon and unmanned aircraft systems. The versatility of HOVERCAT affords future opportunities to profile the atmospheric column for more comprehensive evaluations of aerosol&ndash;cloud interactions. Based on our test flight experiences, we provide a set of recommendations for future deployments of similar measurement systems and platforms.</p

Multi-model simulations of aerosol and ozone radiative forcing due to anthropogenic emission changes during the period 1990-2015

Over the past few decades, the geographical distribution of emissions of substances that alter the atmospheric energy balance has changed due to economic growth and air pollution regulations. Here, we show the resulting changes to aerosol and ozone abundances and their radiative forcing, using recently updated emission data for the period 1990-2015, as simulated by seven global atmospheric composition models. The models broadly reproduce large-scale changes in surface aerosol and ozone based on observations (e.g., -1 to -3%/yr in aerosols over 30 the US and Europe). The global mean radiative forcing due to ozone and aerosol changes over the 1990-2015 period increased by +0.17 ±0.08 Wm-2, with approximately 1/3 due to ozone. This increase is more strongly positive than that reported in IPCC AR5. The main reasons for the increased positive radiative forcing of aerosols over this period are the substantial reduction of global mean SO2 emissions, which is stronger in the new emission inventory compared to that used in the IPCC analysis, and higher black carbon emissions

HOVERCAT: a novel aerial system for evaluation of aerosol–cloud interactions

Aerosols have a profound impact on cloud microphysics through their ability to serve as ice nucleating particles (INPs). As a result, cloud radiative properties and precipitation processes can be modulated by such aerosol–cloud interactions. However, one of the largest uncertainties associated with atmospheric processes is the indirect effect of aerosols on clouds. The need for more advanced observations of INPs in the atmospheric vertical profile is apparent, yet most ice nucleation measurements are conducted on the ground or during infrequent and intensive airborne field campaigns. Here, we describe a novel measurement platform that is less expensive and smaller (&lt; 5 kg) when compared to traditional aircraft and tethered balloon platforms and that can be used for evaluating two modes of ice nucleation (i.e., immersion and deposition). HOVERCAT (Honing On VERtical Cloud and Aerosol properTies) flew during a pilot study in Colorado, USA, up to 2.6 km above mean sea level (1.1 km above ground level) and consists of an aerosol module that includes an optical particle counter for size distributions (0.38–17 µm in diameter) and a new sampler that collects up to 10 filter samples for offline ice nucleation and aerosol analyses on a launched balloon platform. During the May 2017 test flight, total particle concentrations were highest closest to the ground (up to 50 cm−3 at &lt; 50 m above ground level) and up to 2 in 102 particles were ice nucleation active in the immersion mode (at −23 °C). The warmest temperature immersion and deposition mode INPs (observed up to −6 and −40.4 °C, respectively) were observed closest to the ground, but overall INP concentrations did not exhibit an inverse correlation with increasing altitude. HOVERCAT is a prototype that can be further modified for other airborne platforms, including tethered balloon and unmanned aircraft systems. The versatility of HOVERCAT affords future opportunities to profile the atmospheric column for more comprehensive evaluations of aerosol–cloud interactions. Based on our test flight experiences, we provide a set of recommendations for future deployments of similar measurement systems and platforms.</p

International criteria for electrocardiographic interpretation in athletes: Consensus statement.

Sudden cardiac death (SCD) is the leading cause of mortality in athletes during sport. A variety of mostly hereditary, structural or electrical cardiac disorders are associated with SCD in young athletes, the majority of which can be identified or suggested by abnormalities on a resting 12-lead electrocardiogram (ECG). Whether used for diagnostic or screening purposes, physicians responsible for the cardiovascular care of athletes should be knowledgeable and competent in ECG interpretation in athletes. However, in most countries a shortage of physician expertise limits wider application of the ECG in the care of the athlete. A critical need exists for physician education in modern ECG interpretation that distinguishes normal physiological adaptations in athletes from distinctly abnormal findings suggestive of underlying pathology. Since the original 2010 European Society of Cardiology recommendations for ECG interpretation in athletes, ECG standards have evolved quickly, advanced by a growing body of scientific data and investigations that both examine proposed criteria sets and establish new evidence to guide refinements. On 26-27 February 2015, an international group of experts in sports cardiology, inherited cardiac disease, and sports medicine convened in Seattle, Washington (USA), to update contemporary standards for ECG interpretation in athletes. The objective of the meeting was to define and revise ECG interpretation standards based on new and emerging research and to develop a clear guide to the proper evaluation of ECG abnormalities in athletes. This statement represents an international consensus for ECG interpretation in athletes and provides expert opinion-based recommendations linking specific ECG abnormalities and the secondary evaluation for conditions associated with SCD

Study on Phylogenetic Relationships, Variability, and Correlated Mutations in M2 Proteins of Influenza Virus A

M2 channel, an influenza virus transmembrane protein, serves as an important target for antiviral drug design. There are still discordances concerning the role of some residues involved in proton transfer as well as the mechanism of inhibition by commercial drugs. The viral M2 proteins show high conservativity; about 3/4 of the positions are occupied by one residue in over 95%. Nine M2 proteins from the H3N2 strain and possibly two proteins from H2N2 strains make a phylogenic cluster closely related to 2RLF. The variability range is limited to 4 residues/position with one exception. The 2RLF protein stands out by the presence of 2 serines at the positions 19 and 50, which are in most other M2 proteins occupied by cysteines. The study of correlated mutations shows that there are several positions with significant mutational correlation that have not been described so far as functionally important. That there are 5 more residues potentially involved in the M2 mechanism of action. The original software used in this work (Consensus Constructor, SSSSg, Corm, Talana) is freely accessible as stand-alone offline applications upon request to the authors. The other software used in this work is freely available online for noncommercial purposes at public services on bioinformatics such as ExPASy or NCBI. The study on mutational variability, evolutionary relationship, and correlated mutation presented in this paper is a potential way to explain more completely the role of significant factors in proton channel action and to clarify the inhibition mechanism by specific drugs

Genome Sequence Analysis of Dengue Virus 1 Isolated in Key West, Florida

Dengue virus (DENV) is transmitted to humans through the bite of mosquitoes. In November 2010, a dengue outbreak was reported in Monroe County in southern Florida (FL), including greater than 20 confirmed human cases. The virus collected from the human cases was verified as DENV serotype 1 (DENV-1) and one isolate was provided for sequence analysis. RNA was extracted from the DENV-1 isolate and was used in reverse transcription polymerase chain reaction (RT-PCR) to amplify PCR fragments to sequence. Nucleic acid primers were designed to generate overlapping PCR fragments that covered the entire genome. The DENV-1 isolate found in Key West (KW), FL was sequenced for whole genome characterization. Sequence assembly, Genbank searches, and recombination analyses were performed to verify the identity of the genome sequences and to determine percent similarity to known DENV-1 sequences. We show that the KW DENV-1 strain is 99% identical to Nicaraguan and Mexican DENV-1 strains. Phylogenetic and recombination analyses suggest that the DENV-1 isolated in KW originated from Nicaragua (NI) and the KW strain may circulate in KW. Also, recombination analysis results detected recombination events in the KW strain compared to DENV-1 strains from Puerto Rico. We evaluate the relative growth of KW strain of DENV-1 compared to other dengue viruses to determine whether the underlying genetics of the strain is associated with a replicative advantage, an important consideration since local transmission of DENV may result because domestic tourism can spread DENVs