317 research outputs found

    SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR AUTOMATICALLY SCRAPING CATEGORICAL DATA FROM A PLURALITY OF WEBSITES

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    Systems, methods, and computer program products are provided for automatically scraping categorical data from a plurality of websites. These include: determining a product category; identifying a first website including data associated with the product category; automatically scraping the first website to compile first product data associated with the product category; generating a plurality of web queries based on the compiled first product data; executing the plurality of web queries to identify a plurality of websites; automatically scraping at least a portion of the plurality of websites to compile supplier data associated with suppliers in the product category; and storing at least a portion of the compiled supplier data in a database

    National Party Politics and Supranational Politics in the European Union: New Evidence from the European Parliament

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    Political parties play an important role in structuring political competition at different levels of governance in the European Union (EU). The political parties that contest national elections also participate in the EU legislative institutions, with the governing parties at the national level participating in the Council of Ministers and a broad range of national parties represented in the European Parliament (EP). Recent research indicates that national parties in the EP have formed ideological coalitions -- party groups -- that represent transnational political interests. These party groups appear to manage legislative behavior such that national interests -- which dominate the Council of Ministers -- are subjugated to ideological conflict. In this paper, we demonstrate that the roll-call vote evidence for the impact of party groups in the EP is misleading. Because party groups have incentives to select votes for roll call so as to hide or feature particular voting patterns, the true character of political conflict is never revealed in roll calls.

    A second look at legislative behavior in the European Parliament: roll-call votes and the party system

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    'Jüngste Forschungen zum Wahlverhalten im Europäischen Parlament (EP) kommen zum Schluss, dass die Fraktionen der unterschiedlichen politischen Parteien das legislative Verhalten beeinflussen. Dadurch wird politischer Wettbewerb im EP entlang ideologischer und nicht nationaler Linien organisiert. Daraus folgt, dass das EP eine geeignete Arena für transnationale politische Auseinandersetzungen darstellt. Die Autoren überprüfen nochmals verschiedene empirische Resultate, die diese Schlussfolgerungen unterstützen. Basierend auf der Analyse eines neuen Datensatzes behaupten die, dass die empirische Basis für diese Schlussfolgerungen bedenklich ist. Denn die namentlichen Abstimmungen, welche bisher als Basis zu Studien zum legislativen Abstimmungsverhalten gedient haben, stellen ein verzerrtes Sample für eben solche dar. Es stellt sich somit die allgemeine Frage, inwiefern die bisherige Beschreibung von Parteikohäsion oder die Charakterisierung von Parteienwettbewerb in der Legislative noch Gültigkeit besitzen. Die Resultate weisen außerdem darauf hin, dass die Fraktionen den Großteil ihrer legislativen Abstimmungen vor den Wählern verbergen und somit ihr legislatives Verhalten verschleiern. Obwohl das EP häufig als Quelle für demokratische Legitimation in der EU-Politikgestaltung genannt wird, zeigen die Resultate, dass in der Praxis die verschiedenen Fraktionen die Kontrollmöglichkeiten der Bürger signifikant behindern.' (Autorenreferat)'A great deal of recent research on voting behavior in the European Parliament (EP) concludes that party groups dominate legislative behavior, effectively organizing political competition along ideological rather than national lines. As a result, some argue that the EP is a suitable arena for transnational political contestation. We re-examine several empirical findings used to support these conclusions. Based on an analysis of a novel set of data regarding EP votes that are unrecorded, we argue that the empirical basis for these conclusions is dubious. The fundamental finding is that roll call votes, which form the basis of studies of legislative voting behavior, are a biased sample of legislative votes. This calls into question the accuracy of any description of party unity or the character of party competition on legislation that is gleaned from roll call votes in the EP. In addition, our findings indicate that party groups hide the vast majority of legislative votes from the eyes of voters, therefore obfuscating legislative behavior. Thus, while the EP is often identified as a source of democratic accountability for EU policy-making because its members are directly elected, our findings suggest that in practice party groups significantly obstruct this channel of popular control over policy-making.' (author's abstract)

    Piroplasms of New Zealand seabirds

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    Blood and ectoparasitic ticks were collected from migratory seabirds in New Zealand, including Australasian gannets (n=13) from two sites and red-billed gulls (n=9) and white-fronted terns (n=2) from a third location. Blood smears were screened for parasite presence by microscopy, while DNA from blood samples was subjected to PCR for the presence of tick-transmitted protozoan haemoparasites belonging to the order Piroplasmida. Parasites were identified by comparing small subunit ribosomal RNA (18S rDNA) gene sequences to related sequences on GenBank. Analyses indicated that nine birds were infected with unknown variants of a Babesia poelea-like parasite (recorded as genotypes I and II), while four harboured a piroplasm that was genetically similar to Babesia kiwiensis. There was no parasite stratification by bird species; both the gannets and gulls were positive for all three parasites, while the terns were positive for the B. kiwiensis-like and the B. poelea-like (genotype I) parasites. The B. kiwiensis-like parasite found in the birds was also found in two species of ticks: Carios capensis and Ixodes eudyptidis. This represents the first report of Babesia-positive ticks parasitising seabirds in New Zealand. The lack of host specificity and evidence of wide ranging distributions of the three piroplasm genotypes suggests there is a high degree of haemoparasite transmission occurring naturally between New Zealand seabird populations and species

    An unexpected role for a Wnt-inhibitor: Dickkopf-1 triggers a novel cancer survival mechanism through modulation of aldehyde-dehydrogenase-1 activity

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    It is widely accepted that canonical Wnt (cWnt) signaling is required for the differentiation of osteoprogenitors into osteoblasts. Furthermore, tumor-derived secretion of the cWnt-antagonist Dickkopf-1 (Dkk-1) is known to cause bone destruction, inhibition of repair and metastasis in many bone malignancies, but its role in osteosarcoma (OS) is still under debate. In this study, we examined the role of Dkk-1in OS by engineering its overexpression in the osteochondral sarcoma line MOS-J. Consistent with the known role of Dkk-1 in osteoblast differentiation, Dkk-1 inhibited osteogenesis by the MOSJ cells themselves and also in surrounding tissue when implanted in vivo. Surprisingly, Dkk-1 also had unexpected effects on MOSJ cells in that it increased proliferation and resistance to metabolic stress in vitro and caused the formation of larger and more destructive tumors than controls upon orthotopic implantation. These effects were attributed in part to upregulation of the stress response enzyme and cancer stem cell marker aldehyde-dehydrogenase-1 (ALDH1). Direct inhibition of ALDH1 reduced viability under stressful culture conditions, whereas pharmacological inhibition of cWnt or overexpression of ALDH1 had a protective effect. Furthermore, we observed that ALDH1 was transcriptionally activated in a c-Jun-dependent manner through a pathway consisting of RhoA, MAP-kinase-kinase-4 and Jun N-terminal Kinase (JNK), indicating that noncanonical planar cell polarity-like Wnt signaling was the mechanism responsible. Together, our results therefore demonstrate that Dkk-1 enhances resistance of OS cells to stress by tipping the balance of Wnt signaling in favor of the non-canonical Jun-mediated Wnt pathways. In turn, this results in transcriptional activation of ALDH1 through Jun-responsive promoter elements. This is the first report linking Dkk-1 to tumor stress resistance, further supporting the targeting of Dkk-1 not only to prevent and treat osteolytic bone lesions but also to reduce numbers of stress-resistant tumor cells

    The physical activity experiences of men with serious mental illness: Three short stories

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    Objectives: Although a considerable amount of research has explored the effects of physical activity on mental health, the voices of people with mental illness have been largely excluded from published reports. Through this study we aim to foreground service users' voices in order to shed light on the personal and subjective nature of the relationship between physical activity and serious mental illness (SMI). Methods: An interpretive case study approach was used to explore in depth the physical activity experiences of three men with SMI. Creative analytic practice was used to write three creative non-fictions which, as first-person narratives, foreground the participants' voices. Results: We present three short stories in an effort to communicate participants' personal and subjective experiences of physical activity in an accessible, engaging, and evocative manner. We hope to: (i) provide potentially motivating physical activity success stories for others who live with SMI; (ii) increase awareness among mental health professionals of the possibilities of physical activity; and (iii) provide an empathetic understanding of possibilities and problems of living with SMI which may help challenge the stigma surrounding mental illness. Conclusions: For us, the stories communicate the diversity and difference inherent in the ways men with SMI experience physical activity. We reflect on how the short story form allows these differences to be preserved and respected. We resist making further interpretations of the stories preferring instead to encourage the reader to form her or his own conclusions. © 2007 Elsevier Ltd. All rights reserved

    The motivational antecedents of the development of mental toughness: a self-determination theory perspective

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    Mental toughness is a topic that has received growing attention in psychological literature over the past decade. Although some researchers have attempted to understand how mental toughness is developed, little effort has been made to integrate an understanding of mental toughness development with established psychological theory and research. The aim of our review is to demonstrate the utility of theory and research on motivation for understanding mental toughness and its development. In particular, we propose that self-determination theory provides a sound basis for understanding the motivational antecedents of mental toughness. To achieve our aim, we consider concepts that bridge mental toughness and self-determination theory literature, namely striving, surviving, and thriving. We conclude our review with suggestions for future lines of empirical enquiry that could be pursued to further test our propositions

    The Origins of Mental Toughness – Prosocial Behavior and Low Internalizing and Externalizing Problems at Age 5 Predict Higher Mental Toughness Scores at Age 14

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    Background: The concept of mental toughness (MT) has gained increasing importance among groups other than elite athletes by virtue of its psychological importance and explanatory power for a broad range of health-related behaviors. However, no study has focused so far on the psychological origins of MT. Therefore, the aims of the present study were: to explore, to what extent the psychological profiles of preschoolers aged five were associated with both (1) MT scores and (2) sleep disturbances at age 14, and 3) to explore possible gender differences. Method: Nine years after their first assessment at age five (preschoolers), a total of 77 adolescents (mean age: 14.35 years; SD = 1.22; 42% females) took part in this follow-up study. At baseline, both parents and teachers completed the Strengths and Difficulties Questionnaire (SDQ), covering internalizing and externalizing problems, hyperactivity, negative peer relationships, and prosocial behavior. At follow-up, participants completed a booklet of questionnaires covering socio-demographic data, MT, and sleep disturbances. Results: Higher prosocial behavior, lower negative peer relationships, and lower internalizing and externalizing problems at age five, as rated by parents and teachers, were associated with self-reported higher MT and lower sleep disturbances at age 14. At age 14, and relative to males, females had lower MT scores and reported more sleep disturbances. Conclusion: The pattern of results suggests that MT traits during adolescence may have their origins in the pre-school years

    Effect of a non-dieting lifestyle randomised control trial on psychological well-being and weight management in morbidly obese pre-menopausal women.

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    Objective This study examined the effects of a non-dieting lifestyle intervention approach for morbidly obese women designed in the framework of the self-determination theory (SDT) and Health at Every Size on weight maintenance and psychological functioning. Participants and design Predominantly white (97%), morbidly obese (BMI ≥ 35 kg m-2 with at least one co-morbid condition or a BMI ≥ 40 kg m-2) pre-menopausal women (N = 62), aged between 24 and 55 years were initially randomly assigned to 12 weeks of lifestyle intervention (IIG) or delayed start control group (DSCG). The program consisted of 3 months intensive lifestyle intervention followed by 9 month maintenance phase. The DSCG group commenced the program after 3 months. Results and conclusions Initially, the IIG showed a significant decrease in body weight (baseline to end of the RCT phase) compared with a significant increase in the DSCG group. However, no significant changes in weight status were evident in either group at 12 months compared with baseline. The 3-month intensive intervention resulted in significantly improved psychological functioning in both groups, which were maintained at 12 months. The study provides additional support for a non-dieting, theory-based, lifestyle approach to weight management and psychological well-being among morbidly obese females
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