Trust and control interrelations: New perspectives on the trust control nexus

This article is the post-print version of the published article that may be accessed at the link below. Copyright @ 2007 Sage Publications.This article introduces the special issue on New Perspectives on the Trust-Control Nexus in Organizational Relations. Trust and control are interlinked processes commonly seen as key to reach effectiveness in inter- and intraorganizational relations. The relation between trust and control is, however, a complex one, and research into this relation has given rise to various and contradictory interpretations of how trust and control relate. A well-known discussion is directed at whether trust and control are better conceived as substitutes, or as complementary mechanisms of governance. The articles in this special issue bring the discussion on the relationship between both concepts a step further by identifying common factors, distinctive mechanisms, and key implications relevant for theory building and empirical research. By studying trust and control through different perspectives and at different levels of analysis, the articles provide new theoretical insights and empirical evidence on the foundations of the trust-control interrelations

Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at sNN=2.76\sqrt{s_{\rm NN}}=2.76 TeV

The elliptic, $v_2$, triangular, $v_3$, and quadrangular, $v_4$, azimuthal anisotropic flow coefficients are measured for unidentified charged particles, pions and (anti-)protons in Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 2.76$ TeV with the ALICE detector at the Large Hadron Collider. Results obtained with the event plane and four-particle cumulant methods are reported for the pseudo-rapidity range $|\eta|<0.8$ at different collision centralities and as a function of transverse momentum, $p_{\rm T}$, out to $p_{\rm T}=20$ GeV/$c$. The observed non-zero elliptic and triangular flow depends only weakly on transverse momentum for $p_{\rm T}>8$ GeV/$c$. The small $p_{\rm T}$ dependence of the difference between elliptic flow results obtained from the event plane and four-particle cumulant methods suggests a common origin of flow fluctuations up to $p_{\rm T}=8$ GeV/$c$. The magnitude of the (anti-)proton elliptic and triangular flow is larger than that of pions out to at least $p_{\rm T}=8$ GeV/$c$ indicating that the particle type dependence persists out to high $p_{\rm T}$.Comment: 16 pages, 5 captioned figures, authors from page 11, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186

Point View in Bird and Flower Painting

在中国传统绘画中，点景是极其重要的一种表达方式。石涛所研究的绘画问题中，情感、理性、力量都是不可缺少的，如何恰当地运用这三者，却有可能导致完全不同的创作结果。而点景正是这三者的集合点，不仅要用心灵去感受自然对象的内在精神，不能因为对象的限制而使感受层次也受到限制，把眼睛之受升华为心理之受。在绘画作品中合理地运用点景能使画家的情感与物象更加融合，画家自身的主观感受在画面上得到充分的体现，以一种小的特殊表现符号流露出画家作品里表达的象征倾向和审美概念，对画面的构图及意境有着画龙点睛的作用。本文以花鸟画点景为研究对象，重点介绍了点景的表现与意义；进一步阐述了点景在传统花鸟画构成中的作用，着重论述其在...The “point view” is extremely important as a means of expression in the traditional Chinese painting. Emotion, rationality and power are essential in the Shi Tao studied painting, and how to properly use them may lead to the creation of a completely different result. For the reason that “point view” is a collection of these three points, shouldn’t we only use the soul to feel the inner spirit of n...学位：文学硕士院系专业：艺术教育学院美术系_美术学学号：1862007115166

Whole-genome sequencing reveals host factors underlying critical COVID-19

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

SIDT1 localizes to endolysosomes and mediates double-stranded RNA transport into the cytoplasm

dsRNA is a common by-product of viral replication and acts as a potent trigger of antiviral immunity. SIDT1 and SIDT2 are closely related members of the SID-1 transmembrane family. SIDT2 functions as a dsRNA transporter and is required to traffic internalized dsRNA from endocytic compartments into the cytosol for innate immune activation, but the role of SIDT1 in dsRNA transport and in the innate immune response to viral infection is unclear. In this study, we show that Sidt1 expression is upregulated in response to dsRNA and type I IFN exposure and that SIDT1 interacts with SIDT2. Moreover, similar to SIDT2, SIDT1 localizes to the endolysosomal compartment, interacts with the long dsRNA analog poly(I:C), and, when overexpressed, enhances endosomal escape of poly(I:C) in vitro. To elucidate the role of SIDT1 in vivo, we generated SIDT1-deficient mice. Similar to Sidt2/ mice, SIDT1-deficient mice produced significantly less type I IFN following infection with HSV type 1. In contrast to Sidt2/ mice, however, SIDT1-deficient animals showed no impairment in survival postinfection with either HSV type 1 or encephalomyocarditis virus. Consistent with this, we observed that, unlike SIDT2, tissue expression of SIDT1 was relatively restricted, suggesting that, whereas SIDT1 can transport extracellular dsRNA into the cytoplasm following endocytosis in vitro, the transport activity of SIDT2 is likely to be functionally dominant in vivo

New building of holiday apartment hotel on Dzintaru prospekts 50, Jurmala

Maģistra darba mērķis ir nodrošināt vidēja līmeņa tūristus ar naktsmītnēm Jūrmalā līdz 2016. gadam. Maģistra darbs ietver Jūrmalastūrisma nozares attīstības izpēti un analīzi, risinājuma piedāvājumu, kura realizācijai par pamatu tiks celts jauns dzīvokļa tipa viesu nams. Pētījuma rezultātā tiek noteikta problēma: „Vidēja līmeņa tūristiem Jūrmalas pilsētā nav nodrošinātas iespējas ilgstoši uzturēties tiem pieejamos viesu namos.”. Problēmas risināšanai darba autors izstrādā projektu, kura ietvaros tiek nodibināts uzņēmums, uzcelts jauns labiekārtots dzīvokļa tipa viesu nams, izstrādāta mājas lapa, iegādātas nepieciešamās tehnikas iekārtas un noslēgti līgumi ar pakalpojumu sniedzējiem saimnieciskās darbības nodrošināšanai. Maģistra darbs sastāv no 97 lappusēm un 31 pielikuma.Target of Master'stask is to provide intermediate-level tourists with accommodation in Jurmala by 2016th year. Master's task includes Jurmala tourism development research and analysis, solutions off the realization of new built apartment type holiday guest house. In research will be fixed the problem, “mid-level” tourists in Jurmala have not places for along-stay guest houses with affordable prices to them". To solve these problems, the author develops a project, creating new company, build new apartment type holiday guest house, designing website, purchase the necessary technical equipment and create contracts with providers of economic activity. Master’s work containes 97 pages and 31 attachment