Beyond the two-infall model I. Indications for a recent gas infall with Gaia DR3 chemical abundances

The recent Gaia Data Release 3 (DR3) represents an unparalleled revolution in Galactic Archaeology, providing us with numerous radial velocities chemical abundances for millions of stars, with all-sky coverage. We present a new chemical evolution model for the Galactic disc components (high- and low- $\alpha$ sequence stars) designed to reproduce the new abundance ratios provided by the GSP-spec module for the Gaia DR3 and also constrained by the detailed star formation histories for both the thick and thin disc stars inferred from previous Gaia releases. Sophisticated modeling based on previous Gaia releases has found evidence for narrow episodes of enhanced SF inferred in recent time. Additionally, Gaia DR3 highlighted the presence of young (massive) low-$\alpha$ disc stars which show evidence of a recent chemical impoverishment in several elements. Hence, in this study, we compare Gaia DR3 chemical abundances with the predictions of a three-infall chemical evolution model for the high- and low-$\alpha$ components. The proposed three-infall chemical evolution model nicely reproduces the main features of the abundance ratio [X/Fe] versus [M/H] (X=Mg, Si, Ca, Ti, $\alpha$) of Gaia DR3 stars in different age bins for the considered $\alpha$ elements. Moreover, the most recent gas infall - which started $\sim$ 2.7 Gyr ago - allows us to predict well the Gaia DR3 young population which has experienced a recent chemical impoverishment.Comment: Accepted for publication in Astronomy and Astrophysics (A&A), 17 pages, 16 figure

Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer

A polymorphism in hMSH2 gene has been associated with an increased susceptibility to develop colorectal cancer (CRC). Here we show that it is a genetic risk factor for CRC in the Spanish population. However, its presence does not apparently affect hMSH2 function. © 2000 Cancer Research Campaig

The chemical signature of the Galactic spiral arms revealed by Gaia DR3

Taking advantage of the recent Gaia Data Release 3 (DR3), we map chemical inhomogeneities in the Milky Way's disc out to a distance of $\sim$ 4 kpc from the Sun, using different samples of bright giant stars. The samples are selected using effective temperatures and surface gravities from the GSP-Spec module, and are expected to trace stellar populations of different typical age. The cool (old) giants exhibit a relatively smooth radial metallicity gradient with an azimuthal dependence. Binning in Galactic azimuth $\phi$, the slope gradually varies from $d$[M/H]$/dR \sim -0.054$ dex kpc$^{-1}$ at $\phi \sim -20^{\circ}$ to $\sim -0.035$ dex kpc$^{-1}$ at $\phi \sim 20^{\circ}$. On the other hand, the relatively hotter (and younger) stars present remarkable inhomogeneities, apparent as three (possibly four) metal-rich elongated features in correspondence of the spiral arms' locations in the Galactic disc. When projected onto Galactic radius, those features manifest themselves as statistically significant bumps on top of the observed radial metallicity gradients with amplitudes up to $\sim 0.05-0.1$ dex, making the assumption of a linear radial decrease not applicable to this sample. The strong correlation between the spiral structure of the Galaxy and the observed chemical pattern in the young sample indicates that the spiral arms might be at the origin for the detected chemical inhomogeneities. In this scenario, the spiral arms would leave in the younger stars a strong signature, which progressively disappears when cooler (and older) giants are considered.Comment: 9 pages, 6 figures. Accepted for publication in A&A Letter

The cerium content of the Milky Way as revealed by Gaia DR3 GSP-Spec abundances

[Abstract]: The recent Gaia third data release contains a homogeneous analysis of millions of high-quality Radial Velocity Spectrometer (RVS) stellar spectra by the GSP-Spec module. This led to the estimation of millions of individual chemical abundances and allows us to chemically map the Milky Way. The published GSP-Spec abundances include three heavy elements produced by neutron-captures in stellar interiors: Ce, Zr, and Nd. Aims. We study the Galactic content in cerium based on these Gaia/RVS data and discuss the chemical evolution of this element. Methods. We used a sample of about 30 000 local thermal equilibrium Ce abundances, selected after applying different combinations of GSP-Spec flags. Based on the Gaia DR3 astrometric data and radial velocities, we explore the cerium content in the Milky Way and, in particular, in its halo and disc components. Results. The high quality of the Ce GSP-Spec abundances is quantified through literature comparisons. We found a rather flat [Ce/Fe] versus [M/H] trend. We also found a flat radial gradient in the disc derived from field stars and, independently, from about 50 open clusters. This agrees with previous studies. The [Ce/Fe] vertical gradient was also estimated. We also report an increasing [Ce/Ca] versus [Ca/H] in the disc, illustrating the late contribution of asymptotic giant branch stars with respect to supernovae of type II. Our cerium abundances in the disc, including the young massive population, are well reproduced by a new three-infall chemical evolution model. In the halo population, the M 4 globular cluster is found to be enriched in cerium. Moreover, 11 stars with cerium abundances belonging to the Thamnos, Helmi Stream, and Gaia-Sausage-Enceladus accreted systems were identified from chemo-dynamical diagnostics. We found that the Helmi Stream might be slightly underabundant in cerium compared to the two other systems. Conclusions. This work illustrates the high quality of the GSP-Spec chemical abundances, which significantly contribute to unveiling the heavy-element evolution history of the Milky Way.We thank the referee for their valuable comments. ES received funding from the European Union’s Horizon 2020 research and innovation program under SPACE-H2020 grant agreement number 101004214 (EXPLORE project). ARB also acknowledges support from this Horizon program. PAP and EP thanks the Centre National d’Etudes Spatiales (CNES) for funding support. VG acknowledges support from the European Research Council Consolidator Grant funding scheme (project ASTEROCHRONOMETRY, G.A. n. 772293, http://www.asterochronometry.eu ). Special thanks to Niels Nieuwmunster and Botebar for grateful comments on figures. This work has made use of data from the European Space Agency (ESA) mission Gaia ( https://www.cosmos.esa.int/gaia ), processed by the Gaia Data Processing and Analysis Consortium (DPAC, https://www.cosmos.esa.int/web/gaia/dpac/consortium ). Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement

The cerium content of the Milky Way as revealed by Gaia DR3 GSP-Spec abundances

The recent Gaia Third Data Release contains a homogeneous analysis of millions of high-quality Radial Velocity Spectrometer (RVS) stellar spectra by the GSP-Spec module. This lead to the estimation of millions of individual chemical abundances and allows us to chemically map the Milky Way. Among the published GSP-Spec abundances, three heavy-elements produced by neutron-captures in stellar interiors can be found: Ce, Zr and Nd. We use a sample of about 30,000 LTE Ce abundances, selected after applying different combinations of GSP-Spec flags. Thanks to the Gaia DR3 astrometric data and radial velocities, we explore the cerium content in the Milky Way and, in particular, in its halo and disc components. The high quality of the Ce GSP-Spec abundances is quantified thanks to literature comparisons. We found a rather flat [Ce/Fe] versus [M/H] trend. We also found a flat radial gradient in the disc derived from field stars and, independently, from about 50 open clusters, in agreement with previous studies. The [Ce/Fe] vertical gradient has also been estimated. We also report an increasing [Ce/Ca] vs [Ca/H] in the disc, illustrating the late contribution of AGB with respect to SN II. Our cerium abundances in the disc, including the young massive population, are well reproduced by a new three-infall chemical evolution model. Among the halo population, the M 4 globular cluster is found to be enriched in cerium. Moreover, eleven stars with cerium abundances belonging to the Thamnos, Helmi Stream and Gaia-Sausage-Enceladus accreted systems were identified from chemo-dynamical diagnostics. We found that the Helmi Stream could be slightly underabundant in cerium, compared to the two other systems. This work illustrates the high quality of the GSP-Spec chemical abundances, that significantly contributes to unveil the heavy elements evolution history of the Milky Way.Comment: 15 pages, 10 figures, submitted to A&

Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure.

Platelet-activating anti-platelet factor 4 (PF4)/heparin antibodies and anti-PF4 antibodies cause heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombocytopenia and thrombosis (VITT), respectively. Diagnostic and treatment considerations differ somewhat between HIT and VITT. We identified patients with thrombocytopenia and thrombosis without proximate heparin exposure or adenovirus-based vaccination who tested strongly positive by PF4/polyanion enzyme-immunoassays and negative/weakly positive by heparin-induced platelet activation (HIPA) test but strongly positive by PF4-induced platelet activation (PIPA) test (ie, VITT-like profile). We tested these patients by a standard chemiluminescence assay that detects anti-PF4/heparin antibodies found in HIT (HemosIL AcuStar HIT-IgG(PF4-H)) as well as a novel chemiluminescence assay for anti-PF4 antibodies found in VITT. Representative control sera included an exploratory anti-PF4 antibody-positive but HIPA-negative/weak cohort obtained before 2020 (n = 188). We identified 9 patients with a clinical-pathological profile of a VITT-like disorder in the absence of proximate heparin or vaccination, with a high frequency of stroke (arterial, n = 3; cerebral venous sinus thrombosis, n = 4), thrombocytopenia (median platelet count nadir, 49 × 109/L), and hypercoagulability (greatly elevated D-dimer levels). VITT-like serological features included strong reactivity by PIPA (aggregation <10 minutes in 9/9 sera) and positive testing in the novel anti-PF4 chemiluminescence assay (3/9 also tested positive in the anti-PF4/heparin chemiluminescence assay). Our exploratory cohort identified 13 additional patient sera obtained before 2020 with VITT-like anti-PF4 antibodies. Platelet-activating VITT-like anti-PF4 antibodies should be considered in patients with thrombocytopenia, thrombosis, and very high D-dimer levels, even without a proximate exposure to heparin or adenovirus vector vaccines

Geometry of the Draco C1 Symbiotic Binary

Draco C1 is a known symbiotic binary star system composed of a carbon red giant and a hot, compact companion -- likely a white dwarf -- belonging to the Draco dwarf spheroidal galaxy. From near-infrared spectroscopic observations taken by the Apache Point Observatory Galactic Evolution Experiment (APOGEE-2), part of Sloan Digital Sky Survey IV, we provide updated stellar parameters for the cool, giant component, and constrain the temperature and mass of the hot, compact companion. Prior measurements of the periodicity of the system, based on only a few epochs of radial velocity data or relatively short baseline photometric observations, were sufficient only to place lower limits on the orbital period ($P > 300$ days). For the first time, we report precise orbital parameters for the binary system: With 43 radial velocity measurements from APOGEE spanning an observational baseline of more than 3 years, we definitively derive the period of the system to be $1220.0^{+3.7}_{-3.5}$ days. Based on the newly derived orbital period and separation of the system, together with estimates of the radius of the red giant star, we find that the hot companion must be accreting matter from the dense wind of its evolved companion.Comment: 8 pages, 4 figures, 1 table. Accepted for publication in ApJ

Solid confirmation of the broad DIB around 864.8 nm using stacked Gaia–RVS spectra

Context. Studies of the correlation between different diffuse interstellar bands (DIBs) are important for exploring their origins. However, the Gaia–RVS spectral window between 846 and 870 nm contains few DIBs, the strong DIB at 862 nm being the only convincingly confirmed one. / Aims. Here we attempt to confirm the existence of a broad DIB around 864.8 nm and estimate its characteristics using the stacked Gaia–RVS spectra of a large number of stars. We study the correlations between the two DIBs at 862 nm (λ862) and 864.8 nm (λ864.8), as well as the interstellar extinction. / Methods. We obtained spectra of the interstellar medium (ISM) absorption by subtracting the stellar components using templates constructed from real spectra at high Galactic latitudes with low extinctions. We then stacked the ISM spectra in Galactic coordinates (ℓ,  b) – pixelized by the HEALPix scheme – to measure the DIBs. The stacked spectrum is modeled by the profiles of the two DIBs, Gaussian for λ862 and Lorentzian for λ864.8, and a linear continuum. We report the fitted central depth (CD), central wavelength, equivalent width (EW), and their uncertainties for the two DIBs. / Results. We obtain 8458 stacked spectra in total, of which 1103 (13%) have reliable fitting results after applying numerous conservative filters. This work is the first of its kind to fit and measure λ862 and λ864.8 simultaneously in cool-star spectra. Based on these measurements, we find that the EWs and CDs of λ862 and λ864.8 are well correlated with each other, with Pearson coefficients (rp) of 0.78 and 0.87, respectively. The full width at half maximum (FWHM) of λ864.8 is estimated as 1.62 ± 0.33 nm which compares to 0.55 ± 0.06 nm for λ862. We also measure the vacuum rest-frame wavelength of λ864.8 to be λ0 = 864.53 ± 0.14 nm, smaller than previous estimates. / Conclusions. We find solid confirmation of the existence of the DIB around 864.8 nm based on an exploration of its correlation with λ862 and estimation of its FWHM. The DIB λ864.8 is very broad and shallow. That at λ862 correlates better with E(BP − RP) than λ864.8. The profiles of the two DIBs could strongly overlap with each other, which contributes to the skew of the λ862 profile

Ultracool dwarfs in Gaia DR3

Aims. In this work we use the Gaia DR3 set of ultracool dwarf candidates and complement the Gaia spectrophotometry with additional photometry in order to characterise its global properties. This includes the inference of the distances, their locus in the Gaia colour-absolute magnitude diagram and the (biased through selection) luminosity function in the faint end of the Main Sequence. We study the overall changes in the Gaia RP spectra as a function of spectral type. We study the UCDs in binary systems, attempt to identify low-mass members of nearby young associations, star forming regions and clusters, and analyse their variability properties. Results. We detect 57 young, kinematically homogeneous groups some of which are identified as well known star forming regions, associations and clusters of different ages. We find that the primary members of 880 binary systems with a UCD belong mainly to the thin and thick disk components of the Milky Way. We identify 1109 variable UCDs using the variability tables in the Gaia archive, 728 of which belong to the star forming regions defined by HMAC. We define two groups of variable UCDs with extreme bright or faint outliers. Conclusions. The set of sources identified as UCDs in the Gaia archive contains a wealth of information that will require focused follow-up studies and observations. It will help to advance our understanding of the nature of the faint end of the Main Sequence and the stellar/substellar transition.Comment: Accepted by Astronomy and Astrophysics. 29 pages, 20 figures plus 3 appendice

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected