265 research outputs found

    Promoting Sustainability through Internationalisation at Home in Ireland

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    Celebrating the contribution of internationalisation towards UN Sustainable Development Goals (SDGs), this poster reflects how institutions in Ireland and globally can foster sustainability through internationalisation at home (IaH). IaH directly contributes to the three main SDGs namely SDG 4 on Quality Education, SDG 10 on Reducing Inequalities and SDG17 on Partnership for the Goals

    Promoting Equality, Diversity, and Inclusion through Internationalisation at Home in Ireland

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    This poster on 'Promoting Equality, Diversity, and Inclusion through Internationalisation at Home in Ireland' was presented at the South East Technological University Equitas - EDI in Higher Education Conference held on May 25-26, 2023. It focuses on Internationalisation at Home (IaH) and highlights the pathways in which Irish HEIs can embed IaH in third-level curricula addressing inequalities in internationalisation experiences. As student mobility remains limited to a privileged few, this poster showcases how IaH can provide inclusive international and intercultural learning opportunities for all students, irrespective of their participation in mobility programs. This research aligns with the United Nations #SDGs, emphasising our commitment to fostering global citizenship and advancing equitable education. Let's embrace diversity, promote equality, and prepare students for the global world of work, both abroad and at home in Ireland

    Pushing Boundaries through Borderless Education- The Power of Internationalisation at Home : Preparing for the Changing Context of Higher Education in Ireland

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    This poster aims to captivate a broader audience and shed light on a ground-breaking research project focused on the untapped potential of Internationalisation at Home (IaH). It explores how this innovative approach pushes the boundaries of conventional learning methods. The poster effectively utilises an 'IaH funnel' as a compelling visual metaphor to depict the research project's journey and its intended outcomes. The funnel illustrates the transformative process of integrating internationalisation into the curriculum, thereby enriching the learning experience. The impact section of the poster showcases a cup with a globe depicted as a tea bag, symbolising the infusion of internationalisation into the Irish Higher Education system. This imagery effectively conveys the positive effects and benefits that arise from embracing IaH. By disseminating the significance of IaH through this thought-provoking poster, the research team endeavors to raise awareness about the potential of borderless education and inspire a wider audience to explore new horizons in education

    Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector

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    Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente

    Estimation of Transmission Parameters of H5N1 Avian Influenza Virus in Chickens

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    Despite considerable research efforts, little is yet known about key epidemiological parameters of H5N1 highly pathogenic influenza viruses in their avian hosts. Here we show how these parameters can be estimated using a limited number of birds in experimental transmission studies. Our quantitative estimates, based on Bayesian methods of inference, reveal that (i) the period of latency of H5N1 influenza virus in unvaccinated chickens is short (mean: 0.24 days; 95% credible interval: 0.099–0.48 days); (ii) the infectious period of H5N1 virus in unvaccinated chickens is approximately 2 days (mean: 2.1 days; 95%CI: 1.8–2.3 days); (iii) the reproduction number of H5N1 virus in unvaccinated chickens need not be high (mean: 1.6; 95%CI: 0.90–2.5), although the virus is expected to spread rapidly because it has a short generation interval in unvaccinated chickens (mean: 1.3 days; 95%CI: 1.0–1.5 days); and (iv) vaccination with genetically and antigenically distant H5N2 vaccines can effectively halt transmission. Simulations based on the estimated parameters indicate that herd immunity may be obtained if at least 80% of chickens in a flock are vaccinated. We discuss the implications for the control of H5N1 avian influenza virus in areas where it is endemic

    Suppression of Lung Tumorigenesis by Leucine Zipper/EF Hand–Containing Transmembrane-1

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    Leucine zipper/EF hand-containing transmembrane-1 (LETM1) encodes for the human homologue of yeast Mdm38p, which is a mitochondria-shaping protein of unclear function. However, a previous study demonstrated that LETM1 served as an anchor protein for complex formation between mitochondria and ribosome, and regulated mitochondrial biogenesis.Therefore, we examine the possibility that LETM1 may function to regulate mitochondria and lung tumor growth. In this study, we addressed this question by studying in the effect of adenovirus-mediated LETM1 in the lung cancer cell and lung cancer model mice. To investigate the effects of adenovirus-LETM1 in vitro, we infected with adenovirus-LETM1 in A549 cells. Additionally, in vivo effects of LETM1 were evaluated on K-ras(LA1) mice, human non-small cell lung cancer model mice, by delivering the LETM1 via aerosol through nose-only inhalation system. The effects of LETM1 on lung cancer growth and AMPK related signals were evaluated. Adenovirus-mediated overexpression of LETM1 could induce destruction of mitochondria of lung cancer cells through depleting ATP and AMPK activation. Furthermore, adenoviral-LETM1 also altered Akt signaling and inhibited the cell cycle while facilitating apoptosis. Theses results demonstrated that adenovirus-LETM1 suppressed lung cancer cell growth in vitro and in vivo.Adenovirus-mediated LETM1 may provide a useful target for designing lung tumor prevention and treatment
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