Determination of 24 primary aromatic amines in aqueous food simulants by combining solid phase extraction and salting-out assisted liquid?liquid extraction with liquid chromatography tandem mass spectrometry

Carcinogenic primary aromatic amines (PAAs) can be released from improperly manufactured food packaging materials. The limit for the sum of PAAs is set to 10 ?gkg- 1 in Commission Regulation No. 10/2011 (FCM Regulation). However, a lower individual limit, 2 ?gkg- 1 has been recently introduced for the carcinogenic PAAs in Commission Regulation No. 2020/1245. As the majority of the previously published methods are no longer compliant with the current regulation, a UHPLC-MS/MS method was developed to enable food packaging compliance testing for PAAs not only from 3% (w/v) acetic acid, but also from 10% (v/v) ethanol food simulant. Since the latest amendment of the FCM Regulation refers to the list of the 22 restricted PAAs of EU Regulation No. 1907/2006, these PAAs were selected as target compounds along with aniline and p-toluidine, the most common impurities of azo colorants and isocyanates. An enrichment factor of 20 could be achieved combining solid phase extraction with salting-out assisted liquid?liquid extraction. The method was successfully validated and applied on real samples. Limit of quantitation (LOQ) and limit of detection (LOD) values were 0.15 ?gL-1 and 0.05 ?gL-1 for both food simulants, respectively; except for 2,4-diaminotoluene, aniline and 4,4?-oxydianiline. However, even these compounds had lower LOD values than the new individual limit of 2 ?gkg- 1. Cumulative LOD values for both food simulants (1.6 ?gL-1 and 1.5 ?gL-1 for 3% (w/v) acetic acid and 10% (v/v) ethanol, respectively) were lower than the 10 ?gkg- 1 specified in the FCM Regulation. Accuracy values were between 70 and 118% for both food simulants for the majority of PAAs. Both within-day and between-day precision values were below 20%. This method proved to be suitable for daily routine analysis enabling compliance testing of food packaging materials according to the latest regulations. The method was successfully applied for the analysis of plastic kitchenware samples

Alignment of the ALICE Inner Tracking System with cosmic-ray tracks

37 pages, 15 figures, revised version, accepted by JINSTALICE (A Large Ion Collider Experiment) is the LHC (Large Hadron Collider) experiment devoted to investigating the strongly interacting matter created in nucleus-nucleus collisions at the LHC energies. The ALICE ITS, Inner Tracking System, consists of six cylindrical layers of silicon detectors with three different technologies; in the outward direction: two layers of pixel detectors, two layers each of drift, and strip detectors. The number of parameters to be determined in the spatial alignment of the 2198 sensor modules of the ITS is about 13,000. The target alignment precision is well below 10 micron in some cases (pixels). The sources of alignment information include survey measurements, and the reconstructed tracks from cosmic rays and from proton-proton collisions. The main track-based alignment method uses the Millepede global approach. An iterative local method was developed and used as well. We present the results obtained for the ITS alignment using about 10^5 charged tracks from cosmic rays that have been collected during summer 2008, with the ALICE solenoidal magnet switched off.Peer reviewe

Transverse momentum spectra of charged particles in proton-proton collisions at s=900\sqrt{s} = 900 GeV with ALICE at the LHC

The inclusive charged particle transverse momentum distribution is measured in proton-proton collisions at $\sqrt{s} = 900$ GeV at the LHC using the ALICE detector. The measurement is performed in the central pseudorapidity region $(|\eta|<0.8)$ over the transverse momentum range $0.15<p_{\rm T}<10$ GeV/$c$. The correlation between transverse momentum and particle multiplicity is also studied. Results are presented for inelastic (INEL) and non-single-diffractive (NSD) events. The average transverse momentum for $|\eta|<0.8$ is $\left<p_{\rm T}\right>_{\rm INEL}=0.483\pm0.001$ (stat.) $\pm0.007$ (syst.) GeV/$c$ and \left_{\rm NSD}=0.489\pm0.001 (stat.) $\pm0.007$ (syst.) GeV/$c$, respectively. The data exhibit a slightly larger $\left<p_{\rm T}\right>$ than measurements in wider pseudorapidity intervals. The results are compared to simulations with the Monte Carlo event generators PYTHIA and PHOJET.Comment: 20 pages, 8 figures, 2 tables, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/390

The ALICE experiment at the CERN LHC

ALICE (A Large Ion Collider Experiment) is a general-purpose, heavy-ion detector at the CERN LHC which focuses on QCD, the strong-interaction sector of the Standard Model. It is designed to address the physics of strongly interacting matter and the quark-gluon plasma at extreme values of energy density and temperature in nucleus-nucleus collisions. Besides running with Pb ions, the physics programme includes collisions with lighter ions, lower energy running and dedicated proton-nucleus runs. ALICE will also take data with proton beams at the top LHC energy to collect reference data for the heavy-ion programme and to address several QCD topics for which ALICE is complementary to the other LHC detectors. The ALICE detector has been built by a collaboration including currently over 1000 physicists and engineers from 105 Institutes in 30 countries. Its overall dimensions are 161626 m3 with a total weight of approximately 10 000 t. The experiment consists of 18 different detector systems each with its own specific technology choice and design constraints, driven both by the physics requirements and the experimental conditions expected at LHC. The most stringent design constraint is to cope with the extreme particle multiplicity anticipated in central Pb-Pb collisions. The different subsystems were optimized to provide high-momentum resolution as well as excellent Particle Identification (PID) over a broad range in momentum, up to the highest multiplicities predicted for LHC. This will allow for comprehensive studies of hadrons, electrons, muons, and photons produced in the collision of heavy nuclei. Most detector systems are scheduled to be installed and ready for data taking by mid-2008 when the LHC is scheduled to start operation, with the exception of parts of the Photon Spectrometer (PHOS), Transition Radiation Detector (TRD) and Electro Magnetic Calorimeter (EMCal). These detectors will be completed for the high-luminosity ion run expected in 2010. This paper describes in detail the detector components as installed for the first data taking in the summer of 2008

Scenic spots : Chinese tourism, the state, and cultural authority

Twenty years ago, commercial tourism in the People’s Republic of China hardly existed. Today, China has a burgeoning tourist industry, characterized by a unique style with deep roots in traditional Chineses culture. Scenic Spots is an exploration of why Chinese tourists pursue certain kinds of experiences, what they make of them, and how their experiences and interpretations are shaped by the state

China and the developing world: Beijing's strategy for the twenty-first century

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