52 research outputs found
Numerical simulation of thermal energy storage with phase change material and aluminum foam
A Latent Heat thermal energy storage system (LHTESS) is employed as a thermal buffer, since it avoids the intermittent supply of thermal energy due to the behaviour of the thermal source, in particular the renewable thermal source like the solar radiation. Therefore a LHTESS allows supplying the thermal energy in continuous way. The principal material of a LHTESS is the phase change material (PCM) given that it storages a high quantity of thermal energy during its phase change process thanks to the high value of latent heat. Moreover the thermal energy is stored at quasi-constant temperature because during the phase change process the heat is engaged to change phase and not to raise the temperature.
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Experimental Investigation on Fluid Dynamic and Thermal Behavior in Confined Impinging Round Jets in Aluminum Foam
In this paper an experimental investigation is carried out on impinging jets in porous media with the wall heated from below with a uniform heat flux. The fluid is air. The experimental apparatus is made up of a fun systems, a test section, a tube, to reduce the section in a circular section. The tube is long 1.0 m and diameter of 0.012 m. The test section has a diameter of 0.10 m and it has the thickness of 10, 20 and 40 mm. In the test section the lower plate is in aluminum and is heated by an electrical resistances whereas the upper plate is in Plexiglas. The experiments are carried out employing aluminum foams with 5, 10 and 40 PPI and three thickness over the heated circular plate. Results are obtained in a Reynolds number range from 500 to 1500 and wall heat flux from 500 W/m2 to 1400 W/m2. Results are given in terms of wall temperature profiles, local and average Nusselt numbers, pressure drops, friction factor and Richardson number. Moreover, to evaluate the improvement due to the presence of the metal foam, it is necessary a quantitative methodology. In this work an energy performance ratio is employed to compare the performances of surface with and without foams in terms of heat transfer coefficients and pressure drops. Preliminarily experimental results has confirmed that the use of the porous medium improves the heat transfer promoting the heat dissipation of the surface with high efficacy but determines an increase in pressure drops
Role of Correlations in the Collective Behavior of Microswimmer Suspensions
International audienceIn this Letter, we study the collective behavior of a large number of self-propelled microswimmers immersed in a fluid. Using unprecedentedly large-scale lattice Boltzmann simulations, we reproduce the transition to bacterial turbulence. We show that, even well below the transition, swimmers move in a correlated fashion that cannot be described by a mean-field approach. We develop a novel kinetic theory that captures these correlations and is nonperturbative in the swimmer density. To provide an experimentally accessible measure of correlations, we calculate the diffusivity of passive tracers and reveal its nontrivial density dependence. The theory is in quantitative agreement with the lattice Boltzmann simulations and captures the asymmetry between pusher and puller swimmers below the transition to turbulence
A Machine Learning-Based Holistic Approach to Predict the Clinical Course of Patients within the Alzheimer’s Disease Spectrum
Background: Alzheimer’s disease (AD) is a neurodegenerative condition driven by multifactorial etiology. Mild cognitive impairment (MCI) is a transitional condition between healthy aging and dementia. No reliable biomarkers are available to predict the conversion from MCI to AD. Objective: To evaluate the use of machine learning (ML) on a wealth of data offered by the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and Alzheimer’s Disease Metabolomics Consortium (ADMC) database in the prediction of the MCI to AD conversion. Methods: We implemented an ML-based Random Forest (RF) algorithm to predict conversion from MCI to AD. Data related to the study population (587 MCI subjects) were analyzed by RF as separate or combined features and assessed for classification power. Four classes of variables were considered: neuropsychological test scores, AD-related cerebrospinal fluid (CSF) biomarkers, peripheral biomarkers, and structural magnetic resonance imaging (MRI) variables. Results: The ML-based algorithm exhibited 86% accuracy in predicting the AD conversion of MCI subjects. When assessing the features that helped the most, neuropsychological test scores, MRI data, and CSF biomarkers were the most relevant in the MCI to AD prediction. Peripheral parameters were effective when employed in association with neuropsychological test scores. Age and sex differences modulated the prediction accuracy. AD conversion was more effectively predicted in females and younger subjects. Conclusion: Our findings support the notion that AD-related neurodegenerative processes result from the concerted activity of multiple pathological mechanisms and factors that act inside and outside the brain and are dynamically affected by age and sex
Motion and dosimetric criteria for selecting gating technique for apical lung lesions in magnetic resonance guided radiotherapy
IntroductionPatients treatment compliance increases during free-breathing (FB) treatment, taking generally less time and fatigue with respect to deep inspiration breath-hold (DIBH). This study quantifies the gross target volume (GTV) motion on cine-MRI of apical lung lesions undergoing a SBRT in a MR-Linac and supports the patient specific treatment gating pre-selection.Material and methodsA total of 12 patients were retrospectively enrolled in this study. During simulation and treatment fractions, sagittal 0.35 T cine-MRI allows real-time GTV motion tracking. Cine-MRI has been exported, and an in-house developed MATLAB script performed image segmentation for measuring GTV centroid position on cine-MRI frames. Motion measurements were performed during the deep inspiration phase of DIBH patient and during all the session for FB patient. Treatment plans of FB patients were reoptimized using the same cost function, choosing the 3 mm GTV-PTV margin used for DIBH patients instead of the original 5 mm margin, comparing GTV and OARs DVH for the different TP.ResultsGTV centroid motion is <2.2 mm in the antero-posterior and cranio-caudal direction in DIBH. For FB patients, GTV motion is lower than 1.7 mm, and motion during the treatment was always in agreement with the one measured during the simulation. No differences have been observed in GTV coverage between the TP with 3-mm and 5-mm margins. Using a 3-mm margin, the mean reduction in the chest wall and trachea–bronchus Dmax was 2.5 Gy and 3.0 Gy, respectively, and a reduction of 1.0 Gy, 0.6 Gy, and 2.3% in Dmax, Dmean, and V5Gy, respectively, of the homolateral lung and 1.7 Gy in the contralateral lung Dmax.DiscussionsCine-MRI allows to select FB lung patients when GTV motion is <2 mm. The use of narrower PTV margins reduces OARs dose and maintains target coverage
Anxiety and depression in keratotic oral lichen planus: a multicentric study from the SIPMO
Objectives: Oral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated with a complex symptomatology and psychological alteration. The aim of the study was to evaluate the prevalence of anxiety (A) and depression (D) in patients with K-OLP, analyzing the potential predictors which can affect mental health status. Methods: Three hundred K-OLP patients versus 300 healthy controls (HC) were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), and Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A) were administered. Results: The K-OLP patients showed statistically higher scores in the NRS, T-PRI, HAM-D, and HAM-A compared with the HC (p-value < 0.001**). A and D were found in 158 (52.7%) and 148 (49.3%) K-OLP patients. Strong linear correlations were identified between HAM-A, HAM-D, NRS, T-PRI, and employment status and between HAM-D, HAM-A, NRS, T-PRI, employment status, and female gender. Multivariate logistic regression revealed that HAM-D and HAM-A showed the greatest increase in the R2 value for A and D in the K-OLP patients, respectively (DR2 = 55.5% p-value < 0.001**; DR2 = 56.5% p-value < 0.001**). Conclusions: The prevalence of A and D is higher in the K-OLP patients compared with the HC, also found in K-OLP subjects without pain, suggesting that the processing of pain may be in a certain way independent of the processing of mood. Clinical relevance: Mood disorders and pain assessment should be carefully performed in relation to K-OLP to obtain a complete analysis of the patients
Black holes, gravitational waves and fundamental physics: a roadmap
The grand challenges of contemporary fundamental physics—dark matter, dark energy, vacuum energy, inflation and early universe cosmology, singularities and the hierarchy problem—all involve gravity as a key component. And of all gravitational phenomena, black holes stand out in their elegant simplicity, while harbouring some of the most remarkable predictions of General Relativity: event horizons, singularities and ergoregions.
The hitherto invisible landscape of the gravitational Universe is being unveiled before our eyes: the historical direct detection of gravitational waves by the LIGO-Virgo collaboration marks the dawn of a new era of scientific exploration. Gravitational-wave astronomy will allow us to test models of black hole formation, growth and evolution, as well as models of gravitational-wave generation and propagation. It will provide evidence for event horizons and ergoregions, test the theory of General Relativity itself, and may reveal the existence of new fundamental fields. The synthesis of these results has the potential to radically reshape our understanding of the cosmos and of the laws of Nature.
The purpose of this work is to present a concise, yet comprehensive overview of the state of the art in the relevant fields of research, summarize important open problems, and lay out a roadmap for future progress. This write-up is an initiative taken within the framework of the European Action on 'Black holes, Gravitational waves and Fundamental Physics'
AN ANENCEPHALIC FOETUS PETRIFIED BY GIROLAMO SEGATO (1792-1836): MORPHO-RADIOLOGICAL STUDY AND HYPHOTESES ABOUT THE METHOD
SUMMARY
In Modern Age’s time the human body became one of the most interesting and generally accepted spectacles underlying changes in mentality. At the same time the problem of preservation of human bodies became a fundamental instrument used by many scholars to improve knowledge in human anatomy. People overcame anthropological taboos and religious resistance providing dissection and exhibition of the body in all its manifestations, normal or pathologic. Segato’s experience became part of this atmosphere in which scientific research was combined with a strong desire for the rare, morbid and marvellous: the descriptive human congenital malformations attracted special attention. We report the case of an anencephalic foetus petrified by Gerolamo Segato in the course of his experiments on body conservation. The specimen has been studied applying non-invasive methods. Digital radiography and computed tomography (CT) alogside more advanced techniques such as three-dimensional (3-D) reconstruction and virtual endoscopy (VE) have been used to investigate anatomic morphology and to perform hypotheses about Segato’s method of petrification which is still unknown
Numerical investigation on a latent thermal energy storage with aluminum foam
In this paper, a numerical investigation on Latent Heat Thermal Energy Storage System (LHTESS) based on a phase change material (PCM) in a metal foam is accomplished. A vertical shell and tube LHTESS made with two concentric aluminum tubes is investigated. The internal surface of the hollow cylinder is at a constant temperature above the PCM melting temperature to simulate the heat transfer from a hot fluid. The other external surfaces are assumed adiabatic. The phase change of the PCM is modeled with the enthalpy porosity theory while the metal foam is considered as a porous media that obeys to the Darcy-Forchheimer law. Local thermal nonequilibrium (LTNE) model is assumed to analyze the metal foam and some comparison are accomplished with the local thermal equilibrium model assumption. The governing equations are solved employing the Ansys-Fluent 15 code. Numerical simulations for PCM, PCM in the porous medium in LTE and in LTNE assumptions are obtained. Results as a function of time for the charging phase are carried out for different porosities and assigned pore per inch (PPI). The results show that at high porosity the LTE and LTNE models have the same melting time while at low porosity the LTNE has a larger melting time. Moreover, the presence of metal foam improves significantly the heat transfer in the LHTESS giving a very faster phase change process with respect to pure PCM, reducing the melting time more than one order of magnitude
Thermal behaviors of latent thermal energy storage system with pcm and aluminum foam
A numerical investigation on LHTESS with PCM is accomplished. The PCM used is paraffin wax. To enhance the heat transfer inside the system a highly conductive material like metal foam and ceramic nanoparticles are used. The latter method of enhancement leads to a new class of material called Nano-PCM. The system under investigation is a typical 70 L water tank filled up with pure PCM or Nano-PCM and a certain number of pipes are located where the Heat Transfer Fluid (HTF) flows. The surfaces of the pipes are assumed at a constant temperature above the melting temperature of the PCM to simulate the heat transfer from the HTF. The enthalpy-porosity theory is employed to simulate the phase change of the PCM while the metal foam is modelled as a porous media that obeys to the Darcy-Forchheimer law. The ceramics nanoparticles are modelled with the single-phase model. The simulations are accomplished for charging-discharging process at different porosities of the metal foam and different concentration of the nanoparticles. The results show that the presence of the metal foam improves the heat transfer in the system respect to the addition of the nanoparticles, reducing the melting time more than one order of magnitude
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