Fine Structure in the Circumstellar Environment of a Young, Solar-like Star: the Unique Eclipses of KH 15D

Results of an international campaign to photometrically monitor the unique pre-main sequence eclipsing object KH 15D are reported. An updated ephemeris for the eclipse is derived that incorporates a slightly revised period of 48.36 d. There is some evidence that the orbital period is actually twice that value, with two eclipses occurring per cycle. The extraordinary depth (~3.5 mag) and duration (~18 days) of the eclipse indicate that it is caused by circumstellar matter, presumably the inner portion of a disk. The eclipse has continued to lengthen with time and the central brightness reversals are not as extreme as they once were. V-R and V-I colors indicate that the system is slightly bluer near minimum light. Ingress and egress are remarkably well modeled by the passage of a knife-edge across a limb-darkened star. Possible models for the system are briefly discussed.Comment: 19 pages, 5 figure

Von Fachlicher Risikoanalyse zu Politischer Risikobewertung: Die Vermittlung von Risikoanalysen im Bevölkerungsschutz in die Bundespolitik

In Deutschland werden seit 2010 im Auftrag des Bundesministeriums des Innern und für Heimat (bis 8. Dezember 2021 Bundesministerium des Innern, für Bau und Heimat), unter der Koordination des Bundesamtes für Bevölkerungsschutz und Katastrophenhilfe (BBK) regelmäßig Risikoanalysen zu unterschiedlichen Risiken erarbeitet und zur politischen Bewertung vor allem an den Innenausschuss des Deutschen Bundestages gesandt. Diese Studie untersucht explorativ die Rahmenbedingungen der politischen Arbeit von Abgeordneten des Deutschen Bundestages und geht der Frage nach, welche Gründe und Bedingungen die Wahrnehmung der Risikoanalysen beeinflussen und die Verwendung dieser für die Entscheidungsfindung und Politikgestaltung erschweren oder erleichtern. Zur Beantwortung dieser Frage wurden 15 leitfadengestützte Interviews mit aktiven und ehemaligen Bundestagsabgeordneten sowie zwei Gruppendiskussionen mit wissenschaftlichen Mitarbeitenden von Bundestagsabgeordneten durchgeführt. Auf der Grundlage eines heuristischen Modells erfolgte eine strukturierte qualitative Inhaltsanalyse des Materials entlang festgelegter Auswertungskategorien. Durch die Analyse konnten grundlegende Rahmenbedingungen für die Arbeits- und Verhaltensweisen der Abgeordneten herausgearbeitet und Gründe aufgezeigt werden, die eine politische Diskussion der Risikoanalysen in der Vergangenheit erschwert haben. Gleichzeitig erzielte die Analyse eine große Anzahl von Anhaltspunkten für direkte oder indirekte Verbesserungen in der kommunikativen Begleitung der Risikoanalysen sowie deren inhaltlicher und visueller Aufbereitung. Zusätzliche Aspekte hinsichtlich der politischen Wahrnehmung und Bewertung der Risikoanalysen konnten im Rahmen einer Analyse politischer Dokumente erarbeitet werden, die über das Dokumentations- und Informationssystem für Parlamentarische Vorgänge (DIP) abrufbar sind. Die Studie stellt abschließend Handlungsempfehlungen für einen erfolgreichen Transfer der Inhalte der Risikoanalysen in die Bundespolitik vor

SODALITE@RT: Orchestrating Applications on Cloud-Edge Infrastructures

AbstractIoT-based applications need to be dynamically orchestrated on cloud-edge infrastructures for reasons such as performance, regulations, or cost. In this context, a crucial problem is facilitating the work of DevOps teams in deploying, monitoring, and managing such applications by providing necessary tools and platforms. The SODALITE@RT open-source framework aims at addressing this scenario. In this paper, we present the main features of the SODALITE@RT: modeling of cloud-edge resources and applications using open standards and infrastructural code, and automated deployment, monitoring, and management of the applications in the target infrastructures based on such models. The capabilities of the SODALITE@RT are demonstrated through a relevant case study

The XMM-Newton Extended Survey of the Taurus Molecular Cloud (XEST)

(abridged:) The XMM-Newton Extended Survey of the Taurus Molecular Cloud (XEST) surveys the most populated ~5 square degrees of the Taurus star formation region, using the XMM-Newton X-ray observatory to study the thermal structure, variability, and long-term evolution of hot plasma, to investigate the magnetic dynamo, and to search for new potential members of the association. Many targets are also studied in the optical, and high-resolution X-ray grating spectroscopy has been obtained for selected bright sources. The X-ray spectra have been coherently analyzed with two different thermal models (2-component thermal model, and a continuous emission measure distribution model). We present overall correlations with fundamental stellar parameters that were derived from the previous literature. A few detections from Chandra observations have been added. The present overview paper introduces the project and provides the basic results from the X-ray analysis of all sources detected in the XEST survey.Comprehensive tables summarize the stellar properties of all targets surveyed. The survey goes deeper than previous X-ray surveys of Taurus by about an order of magnitude and for the first time systematically accesses very faint and strongly absorbed TMC objects. We find a detection rate of 85% and 98% for classical and weak-line T Tau stars (CTTS resp. WTTS), and identify about half of the surveyed protostars and brown dwarfs. Overall, 136 out of 169 surveyed stellar systems are detected. We describe an X-ray luminosity vs. mass correlation, discuss the distribution of X-ray-to-bolometric luminosity ratios, and show evidence for lower X-ray luminosities in CTTS compared to WTTS. Detailed analysis (e.g., variability, rotation-activity relations, influence of accretion on X-rays) will be discussed in a series of accompanying papers.Comment: 75 pg, 77 figs. Accepted by A&A, to appear in a special section/issue dedicated to the XMM-Newton Extended Survey of the Taurus Molecular Cloud (XEST). V2: ASCII Table 14 added. Version with higher resolution figures at http://www.issibern.ch/teams/Taurus/papers.html or http://www.astro.phys.ethz.ch/papers/guedel/guedel_p_nf.htm

Optically-guided frameless linac-based radiosurgery for brain metastases: clinical experience

The purpose of this study was to describe our clinical experience using optically-guided linear accelerator (linac)-based frameless stereotactic radiosurgery (SRS) for the treatment of brain metastases. Sixty-five patients (204 lesions) were treated between 2005 and 2008 with frameless SRS using an optically-guided bite-block system. Patients had a median of 2 lesions (range, 1–13). Prescription dose ranged from 14 to 22 Gy (median, 18 Gy) and was given in a single fraction. Clinical and radiographic evaluation occurred every 2–4 months following treatment. At a median follow-up of 6.2 months, actuarial survival at 12 months was 40% [95% confidence interval (CI), 28–52). Of 135 lesions that were evaluable for local control (LC), 119 lesions (88%) did not show evidence of progression. Actuarial 12 month LC was 76% (95% CI, 66–86). Tumors ≤2 cm in size had a better 12 month LC rate (81% vs. 36%, P = 0.017) than those >2 cm. Adverse events occurred in three patients (5%). Optically-guided linac-based frameless SRS can produce clinical outcomes that compare favorably to frame-based techniques. As this technique is convenient to use and allows for the uncomplicated delivery of hypofractionated radiotherapy, frameless SRS will likely have an increasingly important role in the management of brain metastases

Searching for gas emission lines in Spitzer Infrared Spectrograph (IRS) spectra of young stars in Taurus

Our knowledge of circumstellar disks has traditionally been based on studies of dust. However, gas dominates the disk mass and its study is key to understand the star and planet formation process. Spitzer can access gas emission lines in the mid-infrared, providing new diagnostics of the physical conditions in accretion disks and outflows. We have studied the spectra of 64 pre-main-sequence stars in Taurus using Spitzer/IRS observations. We have detected H2 (17.03, 28.22 $\mu$m) emission in 6 objects, [Ne II] (12.81 $\mu$m) in 18 objects, and [Fe II] (17.93, 25.99 $\mu$m) in 7 objects. [Ne II] detections are found primarily in Class II objects. The luminosity of the [Ne II] line, is in general higher for objects known to drive jets than for those without known jets, but the two groups are not statistically distinguishable. We have searched for correlations between the line luminosities and different parameters related to the star-disk system. The [Ne II] luminosity is correlated with X-ray luminosity for Class II objects. The [NeII] luminosity is correlated with disk mass and accretion rate when the sample is divided into high and low accretors. We also find correlations between [NeII] luminosity and mid-IR continuum luminosity and with luminosity of the [O I] (6300 \AA) line, the latter being an outflow tracer. [Fe II] luminosity correlates with mass accretion rate. No correlations were found between H2 luminosity and several tested parameters. Our study reveals a general trend toward accretion-related phenomena as the origin of the gas emission lines. Shocks in jets and outflowing material are more likely to play a significant role than shocks in infalling material. The role of X-ray irradiation is less prominent but still present for [Ne II], in particular for Class II sources, the lack of correlation between [Fe II] and [Ne II] points toward different emitting mechanisms.Comment: 24 pages, 10 figures Accepted for publication in Astronomy and Astrophysic

A Far-ultraviolet Atlas of Low-resolution Hubble Space Telescope Spectra of T Tauri Stars

We present a far-ultraviolet (FUV) spectral atlas consisting of spectra of 91 pre-main sequence stars. Most stars in this sample were observed with the Space Telescope Imaging Spectrograph (STIS) and Advanced Camera for Surveys (ACS) on the \emph{Hubble Space Telescope} (\emph{HST}). We find strong correlations among the \ion{O}{1} $\lambda$1304 triplet, %\ion{C}{2} $\lambda$1335, the \ion{Si}{4} $\lambda\lambda$1394/1403 doublet, the \ion{C}{4} $\lambda$1549 doublet, and the \ion{He}{2} $\lambda$1640 line luminosities. For classical T Tauri stars (CTTSs), we also find strong correlations between these lines and the accretion luminosity, suggesting that these lines form in processes related to accretion. These FUV line fluxes and X-ray luminosity correlate loosely with large scatters. The FUV emission also correlates well with H$\alpha$, H$\beta$, and \ion{Ca}{2} K line luminosities. These correlations between FUV and optical diagostics can be used to obtain rough estimates of FUV line fluxes from optical observations. Molecular hydrogen (H$_{2}$) emission is generally present in the spectra of actively accreting CTTSs but not the weak-lined T Tauri stars (WTTSs) that are not accreting. The presence of H$_2$ emission in the spectrum of HD 98800 N suggests that the disk should be classified as actively accreting rather than a debris disk. The spectra in the atlas are available at http://archive.stsci.edu/prepds/ttauriatlas.Comment: 89 pages, 30 figures, published in Ap

Silencing and Nuclear Repositioning of the λ5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1

The chromatin regulator Aiolos and the transcriptional coactivator OBF-1 have been implicated in regulating aspects of B cell maturation and activation. Mice lacking either of these factors have a largely normal early B cell development. However, when both factors are eliminated simultaneously a block is uncovered at the transition between pre-B and immature B cells, indicating that these proteins exert a critical function in developing B lymphocytes. In mice deficient for Aiolos and OBF-1, the numbers of immature B cells are reduced, small pre-BII cells are increased and a significant impairment in immunoglobulin light chain DNA rearrangement is observed. We identified genes whose expression is deregulated in the pre-B cell compartment of these mice. In particular, we found that components of the pre-BCR, such as the surrogate light chain genes λ5 and VpreB, fail to be efficiently silenced in double-mutant mice. Strikingly, developmentally regulated nuclear repositioning of the λ5 gene is impaired in pre-B cells lacking OBF-1 and Aiolos. These studies uncover a novel role for OBF-1 and Aiolos in controlling the transcription and nuclear organization of genes involved in pre-BCR function

Cardiovascular disease, risk factors and heart rate variability in the elderly general population: Design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study

BACKGROUND: The increasing burden of cardiovascular diseases (CVD) in the ageing population of industrialized nations requires an intensive search for means of reducing this epidemic. In order to improve prevention, detection, therapy and prognosis of cardiovascular diseases on the population level in Eastern Germany, it is necessary to examine reasons for the East-West gradient of CVD morbidity and mortality, potential causal mechanisms and prognostic factors in the elderly. Psychosocial and nutritional factors have previously been discussed as possible causes for the unexplained part of the East-West gradient. A reduced heart rate variability appears to be associated with cardiovascular disease as well as with psychosocial and other cardiovascular risk factors and decreases with age. Nevertheless, there is a lack of population-based data to examine the role of heart rate variability and its interaction with psychosocial and nutritional factors regarding the effect on cardiovascular disease in the ageing population. There also is a paucity of epidemiological data describing the health situation in Eastern Germany. Therefore, we conduct a population-based study to examine the distribution of CVD, heart rate variability and CVD risk factors and their associations in an elderly East German population. This paper describes the design and objectives of the CARLA Study. METHODS/DESIGN: For this study, a random sample of 45–80 year-old inhabitants of the city of Halle (Saale) in Eastern Germany was drawn from the population registry. By the end of the baseline examination (2002–2005), 1750 study participants will have been examined. A multi-step recruitment strategy aims at achieving a 70 % response rate. Detailed information is collected on own and family medical history, socioeconomic, psychosocial, behavioural and biomedical factors. Medical examinations include anthropometric measures, blood pressure of arm and ankle, a 10-second and a 20-minute electrocardiogram, a general physical examination, an echocardiogram, and laboratory analyses of venous blood samples. On 200 participants, a 24-hour electrocardiogram is recorded. A detailed system of quality control ensures high data quality. A follow-up examination is planned. DISCUSSION: This study will help to elucidate pathways to CVD involving autonomic dysfunction and lifestyle factors which might be responsible for the CVD epidemic in some populations