SABERES E EXPERIÊNCIAS DE GESTANTES SOBRE AUTOCUIDADO PUERPERAL E CUIDADO DO/A RECÉM-NASCIDO/A MEDIANTE PRÁTICAS EDUCATIVAS

Objetivo: analisar saberes e experiências de gestantes sobre o autocuidado puerperal e cuidado do/a recém-nascido/a mediante práticas educativas. Método: estudo qualitativo, com 16 gestantes que frequentavam o pré-natal em maternidade pública de Salvador, Bahia. Aplicou-se, na coleta de dados, roteiro de entrevista semiestruturado e práticas educativas em saúde. Utilizou-se análise de conteúdo na modalidade temática. Resultados: emergiram três categorias: autocuidado no período pós-parto: relevante e indispensável; neonato e amamentação: aprender para melhor cuidar; e práticas educativas na gestação: o resultado esperado. Evidenciou-se necessidade e relevância das práticas educativas desde a gestação, contudo valorizou-se o cuidado do/a recém-nascido/a em relação ao autocuidado da mulher, podendo influenciar no (auto)cuidado das envolvidas. Considerações finais: as práticas educativas realizadas durante o pré-natal ofertaram subsídios para o empoderamento e a autonomia das mulheres ao retornarem ao domicílio, contudo, quando realizadas, distanciavam-se do autocuidado feminino, pois tendiam a valorizar apenas os cuidados destinados ao/a recém-nascido.Descritores: Gestantes. Cuidado Pré-Natal. Educação em Saúde. Conhecimento. Período Pós-Parto

A CULTURA ORGANIZACIONAL DEMARCA A DECISÃO DAS MICRO E PEQUENAS EMPRESAS DE INVESTIREM COM RECURSOS DE TERCEIROS?

Este estudo foi desenvolvido com o objetivo de identificar os fatores que influenciam as decisões de contratação de empréstimos para realizar investimentos em micro e pequenas empresas (MPE), e se este tipo de decisão tem uma relação com um tipo de cultura organizacional empreendedora característico dessa modalidade de empresas. A pesquisa foi feita com 45 MPE constantes no cadastro de clientes de uma instituição financeira de grande porte. Os dados foram coletados com a aplicação de um formulário estruturado, em entrevistas presenciais com os proprietários das empresas. Os resultados mostraram que o principal fator limitante do uso de crédito pelas MPE, para investimentos, são as elevadas taxas de juros praticadas no Brasil. Também mostraram que não há um tipo de cultura organizacional empreendedora que caracterize as MPE e tampouco que caracterize o grupo de MPE que se endividam para investir e as que não o fazem

EPIDEMIOLOGICAL CHARACTERIZATION OF PORCINE TOXOPLASMOSIS IN THE “ALTO SERTÃO” REGION OF SERGIPE, NORTHEASTERN BRAZIL

Toxoplasma gondii is the etiological agent of toxoplasmosis.Serological studies have demonstrated the parasite occurrence in swine from different regions; however there are no studies that can demonstrate epidemiological status of porcine toxoplasmosis in the Brazilian state of Sergipe. The study purposes were to verify the anti-Toxoplasma gondii antibodies presence and identify risk factors associated with infection in pigs. An amount of 230 blood samples of pigs over four months of age from 45 farms were collected and analyzed by indirect immunofluorescence antibody assay. An epidemiological questionnaire was applied on the properties of origin of the animals to identify risk factors associated with theinfection. A seroprevalence of 8.3% with the titre ranging from 64 (15/230) to 1024 (02/230) was found. Animals from the municipalities of Poço Redondo and Canindé de São Francisco showed the highest prevalences, 18.52% (5/27) and 12.90% (4/31), respectively. The seroprevalence found was considered low when compared to previous studies performed in Brazil, particularly in the northeast region. The age of slaughtered animals should be considered and positive association between the variables age and T. gondii infection was found. Most of swine sampled (194/230) were up to six months which may also influence in the seroprevalence. A low anti-T.gondii seroprevalence was observed in the present study, however it is concluded that T. gondii infection is present in pigs population. The knowledge about its frequency contributes to the establishment of strategies for disease control by appliance of prevention measures in livestock production

Complete blood count parameters as biomarkers of retinopathy of prematurity: a Portuguese multicenter study

© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Purpose: To evaluate complete blood count (CBC) parameters in the first week of life as predictive biomarkers for the development of retinopathy of prematurity (ROP). Methods: Multicenter, prospective, observational study of a cohort of preterm infants born with gestational age (GA) < 32 weeks or birth weight < 1500 g in eight Portuguese neonatal intensive care units. All demographic, clinical, and laboratory data from the first week of life were collected. Univariate logistic regression was used to assess risk factors for ROP and then multivariate regression was performed. Results: A total of 455 infants were included in the study. The median GA was 29.6 weeks, and the median birth weight was 1295 g. One hundred and seventy-two infants (37.8%) developed ROP. Median values of erythrocytes (p < 0.001), hemoglobin (p < 0.001), hematocrit (p < 0.001), mean corpuscular hemoglobin concentration (p < 0.001), lymphocytes (p = 0.035), and platelets (p = 0.003) of the group of infants diagnosed with ROP any stage were lower than those without ROP. Mean corpuscular volume (MCV) (p = 0.044), red blood cell distribution width (RDW) (p < 0.001), erythroblasts (p < 0.001), neutrophils (p = 0.030), neutrophils-lymphocytes ratio (p = 0.028), and basophils (p = 0.003) were higher in the ROP group. Higher values of MCV, erythroblasts, and basophils remained significantly associated with ROP after multivariate regression. Conclusion: In our cohort, the increase in erythroblasts, MCV, and basophils in the first week of life was significantly and independently associated with the development of ROP. These CBC parameters may be early predictive biomarkers for ROP.Open access funding provided by FCT|FCCN (b-on). This work was supported by the Laboratório de Genética and the Instituto de Saúde Ambiental (ISAMB) of the Faculdade de Medicina of Universidade de Lisboa and the Instituto de Investigação Científica Bento da Rocha Cabral. The writing of the manuscript was also supported by funds from Fundação para a Ciência e a Tecnologia to ISAMB (ref. UIDB/04295/2020 and UIDP/04295/2020). This work was also part of a doctoral project funding by the company CUF with a PhD grant in Medicine awarded in 2021 and by the Portuguese Society of Ophthalmology with a PhD grant awarded in 2019.info:eu-repo/semantics/publishedVersio

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms