12 research outputs found
"Footnotes in Gaza", El cómic-reportaje como género periodístico
The recent explosion of non-fiction comic has been followed by the birth of a genre characterized by current contents relate. This creative formula imports journalism codes to report facts, through sequential narrative, with a veracity objective. A circumstance which suggests a theoretical conflict against the normative tradition of journalism. This paper investigates the journalistic dimension of these products from an specific case of study: the analysis of Footnotes in Gaza. A comic that won 2010 award for investigative journalism of Fertel Foundation, and whose author, Joe Sacco, is considered one of the most respected names in this trend that hybridizes comics and journalism.La reciente explosión del cómic de no-ficción se ha visto acompañada del nacimiento de un subgénero que se caracteriza por la narración de contenidos de actualidad. Esta fórmula creativa importa códigos del periodismo para informar sobre hechos reales y con voluntad de veracidad en el relato secuencial. Una circunstancia que sugiere un conflicto teórico frente la tradición normativa del periodismo. Este trabajo investiga la dimensión periodística de estos productos a partir de un caso práctico: el análisis de Footnotes in Gaza. Un cómic premiado en 2010 como mejor trabajo periodístico de investigación por la Fundación Fertel y cuyo autor, Joe Sacco, está considerado uno de los nombres más reputados dentro de esta corriente de hibridación de cómic y periodismo
Social, economic, and health impact of the respiratory syncytial virus: a systematic search
BACKGROUND:
Bronchiolitis caused by the respiratory syncytial virus (RSV) and its related complications are common in infants born prematurely, with severe congenital heart disease, or bronchopulmonary dysplasia, as well as in immunosuppressed infants. There is a rich literature on the different aspects of RSV infection with a focus, for the most part, on specific risk populations. However, there is a need for a systematic global analysis of the impact of RSV infection in terms of use of resources and health impact on both children and adults. With this aim, we performed a systematic search of scientific evidence on the social, economic, and health impact of RSV infection.
METHODS:
A systematic search of the following databases was performed: MEDLINE, EMBASE, Spanish Medical Index, MEDES-MEDicina in Spanish, Cochrane Plus Library, and Google without time limits. We selected 421 abstracts based on the 6,598 articles identified. From these abstracts, 4 RSV experts selected the most relevant articles. They selected 65 articles. After reading the full articles, 23 of their references were also selected. Finally, one more article found through a literature information alert system was included.
RESULTS:
The information collected was summarized and organized into the following topics: 1. Impact on health (infections and respiratory complications, mid- to long-term lung function decline, recurrent wheezing, asthma, other complications such as otitis and rhino-conjunctivitis, and mortality; 2. Impact on resources (visits to primary care and specialists offices, emergency room visits, hospital admissions, ICU admissions, diagnostic tests, and treatments); 3. Impact on costs (direct and indirect costs); 4. Impact on quality of life; and 5. Strategies to reduce the impact (interventions on social and hygienic factors and prophylactic treatments).
CONCLUSIONS:
We concluded that 1. The health impact of RSV infection is relevant and goes beyond the acute episode phase; 2. The health impact of RSV infection on children is much better documented than the impact on adults; 3. Further research is needed on mid- and long-term impact of RSV infection on the adult population, especially those at high-risk; 4. There is a need for interventions aimed at reducing the impact of RSV infection by targeting health education, information, and prophylaxis in high-risk populations.The project was funded by an unrestricted grant from AbbVie.S
Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study
Background: Limited studies have evaluated the joint influence of redox-related metals and genetic variation on metabolic pathways. We analyzed the association of 11 metals with metabolic patterns, and the interacting role of candidate genetic variants, in 1145 participants from the Hortega Study, a population-based sample from Spain. Methods: Urine antimony (Sb), arsenic, barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), molybdenum (Mo) and vanadium (V), and plasma copper (Cu), selenium (Se) and zinc (Zn) were measured by ICP-MS and AAS, respectively. We summarized 54 plasma metabolites, measured with targeted NMR, by estimating metabolic principal components (mPC). Redox-related SNPs (N = 291) were measured by oligo-ligation assay. Results: In our study, the association with metabolic principal component (mPC) 1 (reflecting non-essential and essential amino acids, including branched chain, and bacterial co-metabolism versus fatty acids and VLDL subclasses) was positive for Se and Zn, but inverse for Cu, arsenobetaine-corrected arsenic (As) and Sb. The association with mPC2 (reflecting essential amino acids, including aromatic, and bacterial co-metabolism) was inverse for Se, Zn and Cd. The association with mPC3 (reflecting LDL subclasses) was positive for Cu, Se and Zn, but inverse for Co. The association for mPC4 (reflecting HDL subclasses) was positive for Sb, but inverse for plasma Zn. These associations were mainly driven by Cu and Sb for mPC1; Se, Zn and Cd for mPC2; Co, Se and Zn for mPC3; and Zn for mPC4. The most SNP-metal interacting genes were NOX1, GSR, GCLC, AGT and REN. Co and Zn showed the highest number of interactions with genetic variants associated to enriched endocrine, cardiovascular and neurological pathways. Conclusions: Exposures to Co, Cu, Se, Zn, As, Cd and Sb were associated with several metabolic patterns involved in chronic disease. Carriers of redox-related variants may have differential susceptibility to metabolic alterations associated to excessive exposure to metals.This work was supported by the Strategic Action for Research in Health sciences [CP12/03080, PI15/00071, PI10/0082, PI13/01848, PI14/00874, PI16/01402, PI21/00506 and PI11/00726], CIBER Fisio patología Obesidad y Nutrición (CIBEROBN) (CIBER-02-08-2009, CB06/03 and CB12/03/30,016), the State Agency for Research (PID2019-108973RB- C21 and C22), the Valencia Government (GRUPOS 03/101; PROMETEO/2009/029 and ACOMP/2013/039, IDI FEDER/2021/072 and GRISOLIAP/2021/119), the Castilla-Leon Government (GRS/279/A/08) and European Network of Excellence Ingenious Hypercare (EPSS-037093) from the European Commission. The Strategic Action for Research in Health sciences, CIBERDEM and CIBEROBN are initiatives from Carlos III Health Institute Madrid and cofunded with European Funds for Regional Development (FEDER). The State Agency for Research and Carlos III Health Institute belong to the Spanish Ministry of Science and Innovation. ADR received the support of a fellowship from “la Caixa” Foundation (ID 100010434) (fellowship code “LCF/BQ/DR19/11740016”). MGP received the support of a fellowship from “la Caixa” Foundation (ID 100010434, fellowship code LCFLCF/BQ/DI18/11660001). The funding bodies had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.S
Impacts of Use and Abuse of Nature in Catalonia with Proposals for Sustainable Management
This paper provides an overview of the last 40 years of use, and in many cases abuse, of the natural resources in Catalonia, a country that is representative of European countries in general, and especially those in the Mediterranean region. It analyses the use of natural resources made by mining, agriculture, livestock, logging, fishing, nature tourism, and energy production and consumption. This use results in an ecological footprint, i.e., the productive land and sea surface required to generate the consumed resources and absorb the resulting waste, which is about seven times the amount available, a very high number but very similar to other European countries.
This overexploitation of natural resources has a huge impact on land and its different forms of cover, air, and water. For the last 25 years, forests and urban areas have each gained almost 3% more of the territory at the expense of agricultural land; those municipalities bordering the sea have increased their number of inhabitants and activity, and although they only occupy 6.7% of the total surface area, they account for 43.3% of the population; air quality has stabilized since the turn of the century, and there has been some improvement in the state of aquatic ecosystems, but still only 36% are in good condition, while the remainder have suffered morphological changes and different forms of nonpoint source pollution; meanwhile the biodiversity of flora and fauna remains still under threat.
Environmental policies do not go far enough so there is a need for revision of the legislation related to environmental impact and the protection of natural areas, flora, and fauna. The promotion of environmental research must be accompanied by environmental education to foster a society which is Land 2021, 10, 144 3 of 53 more knowledgeable, has more control and influence over the decisions that deeply affect it. Indeed, nature conservation goes hand in hand with other social and economic challenges that require a more sustainable vision. Today’s problems with nature derive from the current economic model, which is environmentally unsustainable in that it does not take into account environmental impacts. Lastly, we propose a series of reasonable and feasible priority measures and actions related to each use made of the country’s natural resources, to the impacts they have had, and to their management, in the hope that these can contribute to improving the conservation and management of the environment and biodiversity and move towards sustainability.info:eu-repo/semantics/publishedVersio
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Advocating for a change of mentality in the development of metadata standards: historical celestial cartography as a specialization example
Viviamo in un contesto tecnologico estremamente mutevole, nel quale la creazione di nuovi strumenti di accesso a dati e informazioni ha incrementato il livello di specializzazione delle necessità informative degli utenti. In tale variabile scenario, anche le norme e il ruolo dei bibliotecari devono trasformarsi assieme ai servizi forniti agli utenti. L'assenza di standard specifici ha spinto i bibliotecari a improvvisare soluzioni locali nella catalogazione di risorse specialistiche, con il conseguente venir meno dei benefici legati all'interoperabilità globale tra le biblioteche e con altri istituti e iniziative. Dal momento che differenti standard di catalogazione, e altresì numerosi modelli concettuali, segnalano la necessità di affrontare specifici bisogni degli utenti, il primo scopo di questo contributo è di sostenere il soddisfacimento di tali necessità nello sviluppo degli standard di metadatazione. In particolare, la nostra metodologia consiste nell'esporre e chiarire i bisogni di una particolare categoria di utenti (astronomi e astrofisici) e proporre l'inserimento negli standard di elementi importanti per la descrizione delle risorse astronomiche. Tramite uno specifico esempio, mostreremo non solamente la possibile applicazione di questi elementi, ma altresì come il miglioramento del livello di specializzazione degli standard, e di conseguenza dei record realizzati sulla base delle loro norme, può certamente contribuire a una soluzione globale per un migliore reperimento dei dati scientifici.We live in a highly volatile technological environment, in which the generation of new data and information access tools has increased the level of specialization of the users’ information needs. In this changeable scenario, standards and the role of librarians must also evolve along with the services provided to users. The lack of specialization in standards is leading librarians to improvise local solutions when cataloguing specialized resources, thus failing to benefit global interoperability among libraries, and with other institutions and initiatives. As different cataloguing standards, as well as many conceptual models, point out the necessity to deal with the specific users’ needs, the main goal of this paper is to advocate for meeting those needs through the development of metadata standards. In particular, our methodology consists in showing and explaining the needs of a particular type of users (astronomers and astrophysicists) and proposing the inclusion in the standards of elements important for the description of historical astronomical resources. Through an example, we show not only the feasibility of application of these elements, but also how the enhancement of the level of specialization of the standards, and therefore of the records made under their rules, can definitely contribute to a global solution for a much improved scientific information retrieval
Recorrido por el entorno del Ribota y del Jalón
El presente trabajo consiste en el estudio de un itinerario en torno a la desembocadura del río Ribota en el río Jalón. El estudio se divide en las siguientes unidades temáticas: 1. Actividades relacionadas con la Geología. 2. Actividades relacionadas con la Física y la Química. 3. Actividades relacionadas con la Biología (fauna y flora). Estas actividades se organizan a su vez en tres bloques: previas a la visita, que tratan de los conocimientos previos y el material necesario; durante la visita, que consisten en la recogida de muestras, medidas de variables y todas aquellas observaciones que contribuyan a los objetivos propuestos en cada unidad temática; y posteriores a la visita, que incluyen el estudio y análisis de la información y material recogidos durante la visita y conclusiones del trabajo.AragónBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5; 28014 Madrid; Tel. +34917748000; [email protected]
Unique amino acid substitutions in the capsid proteins of foot-and-mouth disease virus from a persistent infection in cell culture
Maintenance of a persistent foot-and-mouth disease virus (FMDV) infection in BHK-21 cells involves a coevolution of cells and virus. The resident FMDV undergoes a number of phenotypic changes, including a gradual decrease in virion stability. Here we report the nucleotide sequence of the P1 genomic segment of the virus rescued after 100 passages of the carrier cells (R100). Only 5 of 15 mutations in P1 of R100 were silent. Nine amino acid substitutions were fixed on the viral capsid during persistence, and three of the variant amino acids are not represented in the corresponding position of any picornavirus sequenced to date. Cysteine at position 7 of VP3, that provides disulfide bridges at the FMDV fivefold axis, was substituted by valine, as determined by RNA, cDNA, and protein sequencing. The modified virus shows high buoyant density in cesium chloride and depicts the same sensitivity to photoinactivation by intercalating dyes as the parental FMDV C-S8c1. Amino acid substitutions fixed in VP1 resulted in altered antigenicity, as revealed by reactivity with monoclonal antibodies. In addition to defining at the molecular level the alterations the FMDV capsid underwent during persistence, the results show that positions which are highly invariant in an RNA genome may change when viral replication occurs in a modified environment
ODD 17. ApS les histoires de vie comme technique d’apprentissage social et éducatif
El proyecto ODS17 ApS "Historia de Vica como técnica de aprendizaje social y educativo" busca analizar la introducción de una metodología pedagógica, la técnica de “historias de vida”, en el aprendizaje del estudiantado de Trabajo Social, su transformación y repercusiones, así como dar a conocer los ODS en relación a la temática y las competencias transversales
Esta técnica es el sello identificador de una forma de empirismo, que insiste en una aproximación humanista a la realidad social (Pujada, 2002). La técnica de la historia de vida se toma como punto de referencia o hilo conductor desde el que trabajar los contenidos de la asignatura “Intermediación, Inserción y Prospección Laboral”. Ello supone una opción para descubrir una nueva e interesante forma de fijar el conocimiento asociando teoría y práctica, comprometiéndose a la reflexión y teorización, Se trabajan temáticas de análisis social, económico, político o cultural, profundizando en la historia, el género, las migraciones, la sanidad o laboral.
Se trata de una forma diferente de construir y reflexionar el conocimiento a partir del conjunto de experiencias de los relatos de las personas mayores, familiares y profesionales, de modo que los/as estudiantes se sientan partícipes de su propio proceso de aprendizaje, siendo una forma de adquirir competencias propias de la asignatura.
Desde el curso académico 2023-2024, la temática central de la historia de vida se centra en vida laboral de los abuelos y abuelas del estudiantado, principalmente. En la actualidad, a través de la metodología Aprendizaje Servicio, la propuesta busca salir del aula universitaria, ampliándose y enriqueciéndose.. Así se ha conformado un equipo motor coordinado desde la citada asignatura del Departamento de Trabajo Social y Servicios Sociales de la Facultad de Trabajo Social, Universidad Complutense de Madrid, en el que participan miembros de diversos Institutos de Educación Secundaria: IES Cañada Real de Valmojado (Toledo), Escuela Comarcal Arzobispo Morcillo de Valdemoro ( Madrid), IES La Fortuna de Leganés ( Madrid), IES Gerardo Diego, IES San Juan de la Cruz e IES Camilo José Cela de estos tres últimos pertenecientes a Pozuelo de Alarcón ( Madrid), el departamento de Derecho y Trabajo Social de la Facultad de Ciencias Sociales de la Universidad de Salamanca, En este curso se han sumado Eel IES San Isidro de Azuqueca de Heraneres ( Guadalajara), la asociación Jose Luis en Memoria de Constantina ( Sevilla) así como la Oficina de Atención al Estudiante de la Universidad de Extremadura. Por último, se ha constituido el grupo de trabajo de investigación de Historias de Vida como técnica de aprendizaje social y educativo.Universidad Complutense de MadridDepto. de Trabajo Social y Servicios SocialesFac. de Trabajo SocialTRUEsubmitte