Match running performance during fixture congestion in elite soccer: Research issues and future directions

Match congestion in elite soccer has been proposed to result in residual fatigue and underperformance in ensuing competition due to insufficient recovery time. In this article, matters relating to match congestion and running performance in elite soccer competition are discussed. The authors suggest a need to determine the extent to which elite players are in reality exposed to periods of match congestion hence to potential declines in performance. Despite evidence of exercise-induced muscle damage combined with a decline in physical performance up to 72-hours post-match, research using time-motion analyses suggest running performance represented by distances covered is unaffected over periods of match congestion. The authors recommend analysis of alternative movement variables including accelerations, decelerations and turns that are taxing metabolically and contribute greatly to muscle damage. Moreover, a holistic approach combining subjective ratings with biochemical, hormonal and immunological responses to exercise would be pertinent especially in players frequently exposed to match congestion. Contemporary practitioners typically implement various post-match recovery treatments during dense schedules in an attempt to accelerate recovery and ensure that subsequent running performance is not unduly affected. However, empirical evidence to support their efficacy in maintaining running performance is lacking and the authors recommend controlled intervention studies using match simulations in an attempt to verify their effectiveness. These points are critically addressed using findings from the current scientific literature while gaps in the current body of knowledge and future directions for research are highlighted

An outbreak of Salmonella Typhimurium phage type 135a in a child care centre

The authors report a cluster investigation of four notifications of Salmonella Typhimurium infection amongst children under five years of age within defined geographical area in southwest Brisbane. Eggs purchased from a local supplier who did not comply with recommended cleaning procedures for eggs may have been the source of this outbreak. (non-author abstract

Injury prevention strategies at the FIFA 2014 World Cup: perceptions and practices of the physicians from the 32 participating national teams

Purpose The available scientific research regarding injury prevention practices in international football is sparse. The purpose of this study was to quantify current practice with regard to (1) injury prevention of top-level footballers competing in an international tournament, and (2) determine the main challenges and issues faced by practitioners in these national teams. Methods A survey was administered to physicians of the 32 competing national teams at the FIFA 2014 World Cup. The survey included 4 sections regarding perceptions and practices concerning non-contact injuries: (1) risk factors, (2) screening tests and monitoring tools, (3) preventative strategies and (4) reflection on their experience at the World Cup. Results Following responses from all teams (100%), the present study revealed the most important intrinsic (previous injury, accumulated fatigue, agonist:antagonist muscle imbalance) and extrinsic (reduced recovery time, training load prior to and during World Cup, congested fixtures) risk factors during the FIFA 2014 World Cup. The 5 most commonly used tests for risk factors were: flexibility, fitness, joint mobility, balance and strength; monitoring tools commonly used were: medical screen, minutes/matches played, subjective and objective wellness, heart rate and biochemical markers. The 5 most important preventative exercises were: flexibility, core, combined contractions, balance and eccentric. Conclusions The present study showed that many of the National football (soccer) teams’ injury prevention perceptions and practices follow a coherent approach. There remains, however, a lack of consistent research findings to support some of these perceptions and practices

Defining the risk of human exposure to Australian bat lyssavirus through potential non-bat animal infection

Human infection with Australian bat lyssavirus (ABLV) was first reported in November 1996, six months after the first identification of the virus in a flying fox in May 1996. Only two human cases of ABLV infection have been described to date, although hundreds of potential human exposures to ABLV have been reported. Current public health guidance considers the risk of transmission of ABLV from a dog or cat to a person is very low. Furthermore, owners are advised that although the animal has a remote possibility of being infected with ABLV, it should be observed closely for at least three months and to report any behavioural changes that occur. The authors present two cases where the behaviour of dogs after potential exposure to ABLV posed significant questions for veterinary and public health authorities

IQRray, a new method for Affymetrix microarray quality control, and the homologous organ conservation score, a new benchmark method for quality control metrics.

MOTIVATION: Microarray results accumulated in public repositories are widely reused in meta-analytical studies and secondary databases. The quality of the data obtained with this technology varies from experiment to experiment, and an efficient method for quality assessment is necessary to ensure their reliability. RESULTS: The lack of a good benchmark has hampered evaluation of existing methods for quality control. In this study, we propose a new independent quality metric that is based on evolutionary conservation of expression profiles. We show, using 11 large organ-specific datasets, that IQRray, a new quality metrics developed by us, exhibits the highest correlation with this reference metric, among 14 metrics tested. IQRray outperforms other methods in identification of poor quality arrays in datasets composed of arrays from many independent experiments. In contrast, the performance of methods designed for detecting outliers in a single experiment like Normalized Unscaled Standard Error and Relative Log Expression was low because of the inability of these methods to detect datasets containing only low-quality arrays and because the scores cannot be directly compared between experiments. AVAILABILITY AND IMPLEMENTATION: The R implementation of IQRray is available at: ftp://lausanne.isb-sib.ch/pub/databases/Bgee/general/IQRray.R. CONTACT: [email protected] SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online

Study of star formation in NGC 1084

We present UBVRI broad band, H$\alpha$ narrow band photometry of the star forming complexes in the infra-red bright galaxy NGC 1084. Results of medium resolution spectroscopy of some of the brighter complexes are also discussed. Spectroscopic data is used to better estimate the internal reddening within the galaxy which is found to be highly variable and to calculate metallicity which is close to the solar value. Diagnostic diagram identifies the shocked regions within this galaxy. The narrow band H$\alpha$ flux and its equivalent width are used to determine the star formation rates of the complexes and the distribution of ages. Star formation rates for a few of the complexes are found to be as high as 0.5 $M_{\odot}$/year. The star forming complexes lie in the age range 3 Myr to 6.5 Myr. U-B vs V-I colour-colour mixed population model created using the Starburst99 model colours is used to estimate the ages of the stellar populations present within these regions. Using this technique, it is found that the star formation in NGC 1084 has taken place in a series of short bursts over the last 40 Myr or so. It is proposed that the likely trigger for enhanced star formation is merger with a gas rich dwarf galaxy.Comment: 9 figures and 6 tables, Accepted in MNRAS for publicatio

Effect of Resistance Training on Microvascular Density and eNOS Content in Skeletal Muscle of Sedentary Men

The effects of resistance training (RT) on muscle mass, strength and insulin sensitivity are well established, but the underlying mechanisms are only partially understood. The main aim of this study is to investigate whether RT induces changes in endothelial enzymes of the muscle microvasculature, which would increase NO bioavailability and could contribute to improved insulin sensitivity. Eight previously sedentary males (age 20±0.4y, BMI 24.5±0.9 kg.m-2) completed 6wk of RT 3x/week. Muscle biopsies were taken from the m. vastus lateralis and microvascular density and endothelial specific eNOS content, eNOS Ser1177 phosphorylation and NOX2 content were assessed pre- and post-RT using quantitative immunofluorescence microscopy. Whole body insulin sensitivity (measured as Matsuda Index), microvascular filtration capacity (functional measure of the total available endothelial surface area) and arterial stiffness (augmentation index, central and peripheral pulse wave velocity) were also measured. Measures of microvascular density, microvascular filtration capacity, microvascular eNOS content, basal eNOS phosphorylation and endothelial NOX2 content did not change from pre-RT to post-RT. RT increased insulin sensitivity (P <0.05) and reduced resting blood pressure and augmentation index (P <0.05), but did not change central or peripheral pulse wave velocity. In conclusion RT did not change any measure of muscle microvascular structure or function

Serving highly vulnerable families in home-visitation programs

Home-visitation programs for families with young children are growing in popularity in the US. These programs typically seek to prevent child abuse and neglect and/or promote optimal development for infants, toddlers, and/or preschool-age children. This paper focuses on improving the capacity of home-visitation programs to meet the complex needs of highly vulnerable families with young children. Poverty, maternal depression and substance abuse, and domestic violence are noted as factors that place young children at risk for poor outcomes. The challenges of providing home-visitation services to families in which these risk factors are present are discussed. Family engagement, matching services to families’ needs, and staff capabilities are highlighted as areas in which improvements can be made to enhance home-visitation programs’ capacity to serve highly vulnerable families. Recommendations are given for improving the effectiveness of home-visitation programs in serving these families, as well for addressing policy and research issues related to the further development and evaluation of these programs.First author draf