k-Gerbes, Line Bundles and Anomalies

We use sets of trivial line bundles for the realization of gerbes. For 1-gerbes the structure arises naturally for the Weyl fermion vacuum bundle at a fixed time. The Schwinger term is an obstruction in the triviality of a 1-gerbe.Comment: 26 page

Neutral Particles and Super Schwinger Terms

Z_2-graded Schwinger terms for neutral particles in 1 and 3 space dimensions are considered.Comment: 13 page

ECONOMIC BENEFITS OF CRITICAL HABITAT FOR THE MEXICAN SPOTTED OWL: A SCOPE TEST USING A MULTIPLE-BOUNDED CONTINGENT VALUATION SURVEY

A split-sample design is used to test for a difference between mean willingness to pay (WTP) for protecting the Mexican spotted owl versus protecting 62 threatened/endangered species which includes the Mexican spotted owl. The multiple bounded contingent valuation method is used in a mail survey of U.S. residents. The mean WTP amounts are statistically different at the 0.1 confidence level indicating the multiple-bounded mail survey passes the scope test. The range of estimated benefits of preserving the 4.6 million acres of critical habitat for the Mexican spotted owl substantially outweighs the costs of the recovery effort.Environmental Economics and Policy,

In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver

Cytochrome P450 (CYP) enzymes are widely studied for their involvement in metabolism of drugs and endogenous compounds. In porcine liver, CYP1A2,2Aand 2E1 are important for the metabolism of skatole.Feeding chicory roots to pigs is known to decrease the skatole concentration in plasma and fat. In the present study we investigated the effect of chicory on CYP mRNA and protein expression, as well as their activity. Male pigs were feed dried chicory root for 16 days before liver samples were collected. By the use of RT-PCR and Western blotting we showed that the mRNA and protein expression of CYP1A2 and 2A were increased in chicory fed pigs. The mRNA expression of CYP2E1 was increased, while there was no effect on protein expression. Activity of CYP1A2 and 2A were increased in chicory feed pigs; this was not the case for CYP2E1 activity. In conclusion; oral administration of chicory root for 16 days to pigs increased the mRNA expression of CYP1A2, 2A and 2E1; and the protein expression of CYP1A2 and 2A. The activities of CYP1A2 and 2A were increased

A procedure for standardization of color infrared film response

Various problems with color infrared film used for remote sensing applications which relate to the instability or variability of the relative sensitivities of the dye layers within the film and the resultant variations in color balance are indicated. A procedure developed and utilized to optimize film response and to achieve more consistent results is described. The procedure establishes a sensitometric aim point with which all new batches of film are compared. Through the use of color compensation filters and change in basic exposure, the new film is exposed to produce imagery with the response characteristics of the aim curves

Regulation of cytochrome P450 mRNA expression in primary porcine hepatocytes by selected secondary plant metabolites from chicory (Cichorium intybus L.)

Chicory (Cichorium intybus) has been shown to induce enzymes of pharmacokinetic relevance (cytochrome P450; CYP). The aim of this study was to investigate the effects of selected secondary plant metabolites with a global extract of chicory root, on the expression of hepatic CYP mRNA (1A2, 2A19, 2C33, 2D25, 2E1 and 3A29), using primary porcine hepatocytes. Of the tested secondary plant metabolites, artemisinin, scoparone, lactucin and esculetin all induced increased expression of specific CYPs, while esculin showed no effect. In contrast, a global extract of chicory root decreased the expression of CYP1A2, 2C33, 2D25 and 3A29 at high concentrations. The results suggest that purified secondary metabolites from chicory affect CYP expression and thereby might affect detoxification in general, and that global extracts of plants can have effects different from individual components

Feeding driet chicory root to pigs decrease androstenone accumulation in fat by increasing hepatic 3β hydroxysteroid dehydrogenase expression

The present study investigated the in vivo effect of chicory root on testicular steroid concentrations and androstenone metabolizing enzymes in entire male pigs. Furthermore, the effect on skatole and indole concentrations in plasma and adipose tissue was investigated. The pigs were divided into two groups; one receiving experimental feed containing 10% dried chicory root for 16 days before slaughter, the control group was fed a standard diet. Plasma, adipose and liver tissue samples were collected at slaughter. Plasma was analyzed for the concentration of testosterone, estradiol, insulin-like growth factor 1 (IGF-1), skatole and indole. Adipose tissue was analyzed for the concentration of androstenone, skatole and indole, while the liver tissue was analyzed for mRNA and protein expressions of 3β-hydroxysteroid dehydrogenase (3β-HSD), sulfotransferase 2A1 and heat-shock protein 70 (HSP70). The results showed that the androstenone concentrations in the adipose tissue of chicory fed pigs were significantly (p < 0.05) lower and indole concentrations were higher (p < 0.05) compared to control fed pigs. Moreover the chicory root fed pigs had increased mRNA and protein expression of 3β-HSD and decreased HSP70 expression (p < 0.05). Testosterone and IGF-1 concentrations in plasma as well as skatole concentrations in adipose tissue were not altered by dietary intake of chicory root. It is concluded that chicory root in the dietreduces the concentration of androstenone in adipose tissue via induction of 3�-HSD, and that these changes were not due to increased cellular stress

A Study of Realtime Summarization Metrics

Unexpected news events, such as natural disasters or other human tragedies, create a large volume of dynamic text data from official news media as well as less formal social media. Automatic real-time text summarization has become an important tool for quickly transforming this overabundance of text into clear, useful information for end-users including affected individuals, crisis responders, and interested third parties. Despite the importance of real-time summarization systems, their evaluation is not well understood as classic methods for text summarization are inappropriate for real-time and streaming conditions. The TREC 2013-2015 Temporal Summarization (TREC-TS) track was one of the first evaluation campaigns to tackle the challenges of real-time summarization evaluation, introducing new metrics, ground-truth generation methodology and dataset. In this paper, we present a study of TREC-TS track evaluation methodology, with the aim of documenting its design, analyzing its effectiveness, as well as identifying improvements and best practices for the evaluation of temporal summarization systems