1,776 research outputs found

    The common good and government in Jacques Maritain

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    No cabe duda que Maritain ha tenido una influencia considerable en las ideas políticas contemporáneas, en especial en la denominada social democracia. Es por esto que conviene revisar algunas de sus principales teorías respecto a las formas de gobierno y el bien común. Tratar las formas de gobierno y el bien común en Maritain lleva inevitablemente a tener que considerar aspectos metafísicos y antropológicos, en tanto, en el autor son estos aspectos los que de forma posterior determinan o por lo menos influyen de forma considerable en su teoría política. Como hemos mencionado Maritain concede una importancia significativa a el aspecto antropológico y metafísico, en los relativo al primero, este se hace manifiesto en la noción de persona concebida como un todo, como una realidad sustancial, mientras que el aspecto metafísico puede verse en la idea de Dios como el Bien Común Supremo.There is no doubt that Maritain has had a considerable influence on contemporary political ideas, especially on the so-called social democracy. This is why it is convenient to review some of his main theories regarding the forms of government and the common good. To deal with the forms of government and the common good in Maritain inevitably leads inevitably to consider metaphysical and anthropological aspects, while in the author it is these aspects that subsequently determine or at least considerably influence his political theory. As we have mentioned Maritain grants a significant importance to the anthropological and metaphysical aspect, in those relative to the first, this is made manifest in the notion of person conceived as a whole, as a substantial reality, while the metaphysical aspect can be seen in the idea of God as the Supreme Common Good

    A novel stepwise micro-TESE approach in non obstructive azoospermia

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    Background: The purpose of the study was to investigate whether micro-TESE can improve sperm retrieval rate (SRR) compared to conventional single TESE biopsy on the same testicle or to contralateral multiple TESE, by employing a novel stepwise micro-TESE approach in a population of poor prognosis patients with non-obstructive azoospermia (NOA). Methods: Sixty-four poor prognosis NOA men undergoing surgical testicular sperm retrieval for ICSI, from March 2007 to April 2013, were included in this study. Patients inclusion criteria were a) previous unsuccessful TESE, b) unfavorable histology (SCOS, MA, sclerahyalinosis), c) Klinefelter syndrome. We employed a stepwise micro-TESE consisting three-steps: 1) single conventional TESE biopsy; 2) micro-TESE on the same testis; 3) contralateral multiple TESE. Results: SRR was 28.1 % (18/64). Sperm was obtained in both the initial single conventional TESE and in the following micro-TESE. The positive or negative sperm retrieval was further confirmed by a contralateral multiple TESE, when performed. No significant pre-operative predictors of sperm retrieval, including patients’ age, previous negative TESE or serological markers (LH, FSH, inhibin B), were observed at univariate or multivariate analysis. Micro-TESE (step 2) did not improve sperm retrieval as compared to single TESE biopsy on the same testicle (step 1) or multiple contralateral TESE (step 3). Conclusions: Stepwise micro-TESE could represent an optimal approach for sperm retrieval in NOA men. In our view, it should be offered to NOA patients in order to gradually increase surgical invasiveness, when necessary. Stepwise micro-TESE might also reduce the costs, time and efforts involved in surgery

    Testicular histopathology, semen analysis and FSH, predictive value of sperm retrieval: supportive counseling in case of reoperation after testicular sperm extraction (TESE)

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    Background: To provide indicators for the likelihood of sperm retrieval in patients undergoing testicular sperm extraction is a major issue in the management of male infertility by TESE. The aim of our study was to determine the impact of different parameters, including testicular histopathology, on sperm retrieval in case of reoperation in patients undergoing testicular sperm extraction. Methods: We retrospectively analyzed 486 patients who underwent sperm extraction for intracytoplasmic sperm injection and testicular biopsy. Histology was classified into: normal spermatogenesis; hypospermatogenesis (reduction in the number of normal spermatogenetic cells); maturation arrest (absence of the later stages of spermatogenesis); and Sertoli cell only (absence of germ cells). Semen analysis and serum FSH, LH and testosterone were measured. Results: Four hundred thirty patients had non obstructive azoospermia, 53 severe oligozoospermia and 3 necrozoospermia. There were 307 (63%) successful sperm retrieval. Higher testicular volume, lower levels of FSH, and better histological features were predictive for sperm retrieval. The same parameters and younger age were predictive factors for shorter time for sperm recovery. After multivariable analysis, younger age, better semen parameters, better histological features and lower values of FSH remained predictive for shorter time for sperm retrieval while better semen and histology remained predictive factors for successful sperm retrieval. The predictive capacity of a score obtained by summing the points assigned for selected predictors (1 point for Sertoli cell only, 0.33 points for azoospermia, 0.004 points for each FSH mIU/ml) gave an area under the ROC curve of 0.843. Conclusions: This model can help the practitioner with counseling infertile men by reliably predicting the chance of obtaining spermatozoa with testicular sperm extraction when a repeat attempt is planne

    Teleagro: software architecture of georeferencing and detection of heat of cattle

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    The systems of livestock production contribute in a preponderant way to improve the quality of life of the communities, since it allows to support the production of the daily sustenance of the communities, to conserve the ecosystems, to promote the conservation of the wild life and to satisfy the values and traditions cultural Latin America, with its large wilderness areas, and a privileged climate favors the maintenance of livestock, to meet the demands of food and ensure regional and global food security. In Colombia, the agricultural sector contributes approximately 11.83% of the national GDP at current prices, according to the Bank of the Republic. Likewise, the livestock industry participates with 3.6%, in comparison with other sectors of the agricultural economy, the production of Colombian cattle doubles and triples to other sectors, such as poultry, coffee and floriculture. In addition, it contributes to the generation of employment in more than 25% of the total jobs generated in the agricultural sector and approximately 7% of the total employment of the Colombian economy (http://www.banrep.gov.co/is/pib). Within agricultural production, livestock occupy 38 million hectares, being 9 times larger than the area dedicated to agriculture. However, agriculture contributes 63% of the value of agricultural production, while livestock, mainly extensive, contributes 26% (FEDEGAN, Strategic Livestock Plan 2019). The large proportion of the área with agricultural vocation dedicated to precarious extensive livestock has explained the low agricultural productivity in Colombia, with very serious consequences for human and sustainable development. This document shows the results of the communications, software and hardware platforms to help the livestock sector to manage production

    Políticas públicas y salud mental en infantes en los centros de salud del distrito de Cajamarca, 2022

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    The present investigation raises as a general objective: to determine the relationship that exists between public policies and mental health in the childhood stage in the health centers of the Cajamarca district. We worked under a quantitative approach, the type of research is basic, the design is nonexperimental, with a transverse temporal cut. As a population, the databases of all the health centers within the district of Cajamarca belonging to the regional government were considered, these are three hospitals, a community health center and six medical posts, making a total of 10 health centers, of which 87 cases were studied. The results indicate that public policies are applied at a poor level, stress in infants occurs regularly, depression has a regular frequency, anxiety is between almost absent and regularly frequent, interaction with parents is neglectful and mental health is at a poor level. It is concluded that there is a direct and very strong significant relationship between public policies applied in health centers and mental health (p-value 0 0.001 and Spearman's Rho of 0.878).   La presente investigación plantea como objetivo general: determinar la relación que existe entre las políticas públicas y la salud mental en la etapa de la infancia en los centros de salud del distrito de Cajamarca. Se trabajó bajo un enfoque cuantitativo, tipo de investigación básica, diseño no experimental, de corte temporal transversal. Como población se consideraron las bases de datos de todos los centros de salud dentro del distrito de Cajamarca pertenecientes al gobierno regional estos son tres hospitales, un centro de salud comunitario y seis postas médicas, haciendo un total de 10 centros de salud, de los cuales se estudiaron 385 casos. Los resultados indican que las políticas públicas se aplican en un nivel deficiente, el estrés en los infantes se presenta de forma regular, la depresión presenta una frecuencia regular, la ansiedad está entre casi ausente y regularmente frecuente, la interacción con los padres es de forma negligente y la salud mental se encuentra en un nivel deficiente. Se concluye que existe una relación significativa directa y muy fuerte entre las políticas públicas aplicadas en los centros de salud y la salud mental (p-valor 0 0.001 y Rho de Spearman de 0.878). &nbsp

    Unbalanced Holographic Superconductors and Spintronics

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    We present a minimal holographic model for s-wave superconductivity with unbalanced Fermi mixtures, in 2+1 dimensions at strong coupling. The breaking of a U(1)_A "charge" symmetry is driven by a non-trivial profile for a charged scalar field in a charged asymptotically AdS_4 black hole. The chemical potential imbalance is implemented by turning on the temporal component of a U(1)_B "spin" field under which the scalar field is uncharged. We study the phase diagram of the model and comment on the eventual (non) occurrence of LOFF-like inhomogeneous superconducting phases. Moreover, we study "charge" and "spin" transport, implementing a holographic realization (and a generalization thereof to superconducting setups) of Mott's two-current model which provides the theoretical basis of modern spintronics. Finally we comment on possible string or M-theory embeddings of our model and its higher dimensional generalizations, within consistent Kaluza-Klein truncations and brane-anti brane setups.Comment: 45 pages, 15 figures; v2: two paragraphs below eq. (3.1) slightly modified, figure 5 (left) replaced, references added; v3: typos corrected, comments added, figure 12 replace

    APROVECHAMIENTO DE ESCORIAS METÁLICAS EN LADRILLOS CERÁMICOS: UNA REVISIÓN

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    Este documento presenta una revisión de la literatura sobre el aprovechamiento de diversas escorias metálicas en la fabricación de ladrillos cerámicos, con el objetivo de describir y analizar el comportamiento de estas unidades de ladrillo modificados, que consiste en sustituir un porcentaje del total de arcilla para una unidad de ladrillo, buscando mejorar sus propiedades mecánicas, en investigaciones realizadas, han dado muestra de óptimos resultados, al utilizar escorias de plomo, acero, bronce, ferrocromo, lodos, entre otros, pudiéndose reciclar y darlo el uso ya antes mencionado, así poder disminuir los impactos ambientales, provocadas por la contaminación que dichos residuos generan y agregar un plus en el rubro de la construcción. Se revisaron 35 artículos indexados entre los años 2012 al 2020 los cuales se distribuyen de la siguiente manera: 5 artículos son de Scopus, 3 de ResearchGate, 11 de ScienceDirect y 6 de Scielo, 8 de ProQuest, 2 de Latindex 2.0, sobre escorias metálicas, caracterización de arcillas y ladrillo cerámico

    A gastrointestinal rotavirus infection mouse model for immune modulation studies

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    <p>Abstract</p> <p>Background</p> <p>Rotaviruses are the single most important cause of severe diarrhea in young children worldwide. The current study was conducted to assess whether colostrum containing rotavirus-specific antibodies (Gastrogard-R<sup>®</sup>) could protect against rotavirus infection. In addition, this illness model was used to study modulatory effects of intervention on several immune parameters after re-infection.</p> <p>Methods</p> <p>BALB/c mice were treated by gavage once daily with Gastrogard-R<sup>® </sup>from the age of 4 to 10 days, and were inoculated with rhesus rotavirus (RRV) at 7 days of age. A secondary inoculation with epizootic-diarrhea infant-mouse (EDIM) virus was administered at 17 days of age. Disease symptoms were scored daily and viral shedding was measured in fecal samples during the post-inoculation periods. Rotavirus-specific IgM, IgG and IgG subclasses in serum, T cell proliferation and rotavirus-specific delayed-type hypersensitivity (DTH) responses were also measured.</p> <p>Results</p> <p>Primary inoculation with RRV induced a mild but consistent level of diarrhea during 3-4 days post-inoculation. All mice receiving Gastrogard-R<sup>® </sup>were 100% protected against rotavirus-induced diarrhea. Mice receiving both RRV and EDIM inoculation had a lower faecal-viral load following EDIM inoculation then mice receiving EDIM alone or Gastrogard-R<sup>®</sup>. Mice receiving Gastrogard-R<sup>® </sup>however displayed an enhanced rotavirus-specific T-cell proliferation whereas rotavirus-specific antibody subtypes were not affected.</p> <p>Conclusions</p> <p>Preventing RRV-induced diarrhea by Gastrogard-R<sup>® </sup>early in life showed a diminished protection against EDIM re-infection, but a rotavirus-specific immune response was developed including both B cell and T cell responses. In general, this intervention model can be used for studying clinical symptoms as well as the immune responses required for protection against viral re-infection.</p

    In Vitro Antiophidian Properties of Dipteryx alata Vogel Bark Extracts

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    Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Extracts from Dipteryx alata bark obtained with different solvents (hexane, dichloromethane, ethyl acetate and methanol) were mixed in vitro with Bothrops jararacussu (Bjssu, 40 mu g/mL) and Crotalus durissus terrificus (Cdt, 15 mu g/mL) snake venoms, and applied to a mouse phrenic nerve-diaphragm preparation to evaluate the possible neutralization of venom effects. Cdt venom neurotoxic effect was not inhibited by any of the extracts, while the neurotoxic and myotoxic actions of Bjssu venom were decreased by the methanolic extract. This inhibition appears to be augmented by tannins. Dichloromethane bark extract inhibited similar to 40% of Bjssu venom effects and delayed blockade induced by Cdt. The methodology used to determine which extract was active allows inferring that: (i) phenolic acids and flavonoids contained in the methanolic extract plus tannins were responsible mostly for neutralization of Bjssu effects; (ii) terpenoids from the dichloromethane extract may participate in the anti-Cdt and anti-Bjssu venom effects; (iii) a given extract could not inhibit venoms from different species even if those belong to the same family, so it is improper to generalize a certain plant as antiophidian; (iv) different polarity extracts do not present the same inhibitory capability, thus demonstrating the need for characterizing both venom pharmacology and the phytochemistry of medicinal plant compounds.15959565970Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)PROBIC/UNISOConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPESP [Proc. FAPESP 04/09705-8, 07/53883-6]FAPESP [07/51414-9, 08/05459-3]CNPq [Proc. 302206/2008-6
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